| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Warren B Zigman, Ira T Lot. Alzheimer's disease in Down syndrome: neurobiology and risk. Mental retardation and developmental disabilities research reviews. vol 13. issue 3. 2008-04-11. PMID:17910085. |
down syndrome (ds) is characterized by increased mortality rates, both during early and later stages of life, and age-specific mortality risk remains higher in adults with ds compared with the overall population of people with mental retardation and with typically developing populations. |
2008-04-11 |
2023-08-12 |
Not clear |
| David Patterso. Genetic mechanisms involved in the phenotype of Down syndrome. Mental retardation and developmental disabilities research reviews. vol 13. issue 3. 2008-04-11. PMID:17910086. |
down syndrome (ds) is the most common genetic cause of significant intellectual disability in the human population, occurring in roughly 1 in 700 live births. |
2008-04-11 |
2023-08-12 |
human |
| Leonard Abbeduto, Steven F Warren, Frances A Conner. Language development in Down syndrome: from the prelinguistic period to the acquisition of literacy. Mental retardation and developmental disabilities research reviews. vol 13. issue 3. 2008-04-11. PMID:17910087. |
down syndrome (ds) is associated with abnormalities in multiple organ systems and a characteristic phenotype that includes numerous behavioral features. |
2008-04-11 |
2023-08-12 |
Not clear |
| Ahmad Salehi, Mehrdad Faizi, Pavel V Belichenko, William C Moble. Using mouse models to explore genotype-phenotype relationship in Down syndrome. Mental retardation and developmental disabilities research reviews. vol 13. issue 3. 2008-04-11. PMID:17910089. |
down syndrome (ds) caused by trisomy 21 is characterized by a variety of phenotypes and involves multiple organs. |
2008-04-11 |
2023-08-12 |
mouse |
| Stephanie L Sherman, Emily G Allen, Lora H Bean, Sallie B Freema. Epidemiology of Down syndrome. Mental retardation and developmental disabilities research reviews. vol 13. issue 3. 2008-04-11. PMID:17910090. |
down syndrome (ds) is the most commonly identified genetic form of mental retardation and the leading cause of specific birth defects and medical conditions. |
2008-04-11 |
2023-08-12 |
Not clear |
| Rosa M Angulo-Barroso, Jianhua Wu, Dale A Ulric. Long-term effect of different treadmill interventions on gait development in new walkers with Down syndrome. Gait & posture. vol 27. issue 2. 2008-04-10. PMID:17499993. |
this longitudinal study investigated the long-term effect of different treadmill interventions on the development of gait patterns in infants with down syndrome (ds). |
2008-04-10 |
2023-08-12 |
human |
| Katherine Winter, Lorena Baccaglini, Scott Toma. A review of malocclusion among individuals with mental and physical disabilities. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 28. issue 1. 2008-04-10. PMID:18271770. |
this review examines the reported prevalence of malocclusion in individuals with down syndrome (ds), cerebral palsy (cp), cleft disorders, mental disabilities, and physical disabilities from 1976 to 2004. |
2008-04-10 |
2023-08-12 |
Not clear |
| Robin Roberson, Laura Toso, Daniel Abebe, Catherine Y Spon. Altered expression of KIF17, a kinesin motor protein associated with NR2B trafficking, may mediate learning deficits in a Down syndrome mouse model. American journal of obstetrics and gynecology. vol 198. issue 3. 2008-04-08. PMID:18313453. |
down syndrome (ds), a major cause of mental retardation, affects 1 of 800 newborns. |
2008-04-08 |
2023-08-12 |
mouse |
| Robin Roberson, Laura Toso, Daniel Abebe, Catherine Y Spon. Altered expression of KIF17, a kinesin motor protein associated with NR2B trafficking, may mediate learning deficits in a Down syndrome mouse model. American journal of obstetrics and gynecology. vol 198. issue 3. 2008-04-08. PMID:18313453. |
mouse models for down syndrome have been studied and found to have developmental and learning deficits, including the ts65dn (ds) mouse model. |
2008-04-08 |
2023-08-12 |
mouse |
| M Guijarro, C Valero, B Paule, J Gonzalez-Macias, J A Rianch. Bone mass in young adults with Down syndrome. Journal of intellectual disability research : JIDR. vol 52. issue Pt 3. 2008-04-03. PMID:18261017. |
down syndrome (ds) is a frequent cause of intellectual disability. |
2008-04-03 |
2023-08-12 |
Not clear |
| F A Conners, C J Rosenquist, L Arnett, M S Moore, L E Hum. Improving memory span in children with Down syndrome. Journal of intellectual disability research : JIDR. vol 52. issue Pt 3. 2008-04-03. PMID:18261023. |
down syndrome (ds) is characterized by impaired memory span, particularly auditory verbal memory span. |
2008-04-03 |
2023-08-12 |
Not clear |
| Carla Pinto Moura, Luís Miguel Cunha, Helena Vilarinho, Maria João Cunha, Diamantino Freitas, Miguel Palha, Siegfried M Pueschel, M Pais-Clement. Voice parameters in children with Down syndrome. Journal of voice : official journal of the Voice Foundation. vol 22. issue 1. 2008-04-02. PMID:17014985. |
down syndrome (ds) is the most frequent chromosomal disorder. |
2008-04-02 |
2023-08-12 |
Not clear |
| Cesar A Sommer, Erika C Pavarino-Bertelli, Eny M Goloni-Bertollo, Flavio Henrique-Silv. Identification of dysregulated genes in lymphocytes from children with Down syndrome. Genome. vol 51. issue 1. 2008-04-01. PMID:18356936. |
global transcriptome studies attempting to analyze the consequences of trisomy in down syndrome (ds) tissues have reported conflicting results, which have led to the suggestion that the analysis of specific tissues or cell types may be more productive. |
2008-04-01 |
2023-08-12 |
human |
| Yingyao Chen, Xu Qian, Jie Zhang, Jun Li, Annie Chu, Stuart O Schweitze. Preliminary study into the economic burden of Down syndrome in China. Birth defects research. Part A, Clinical and molecular teratology. vol 82. issue 1. 2008-03-31. PMID:18022893. |
to measure the economic burden of down syndrome (ds) in china is to facilitate strategic planning development for managing and preventing ds. |
2008-03-31 |
2023-08-12 |
Not clear |
| Y Ge, K M LaFiura, A A Dombkowski, Q Chen, S G Payton, S A Buck, S Salagrama, A E Diakiw, L H Matherly, J W Tau. The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. Leukemia. vol 22. issue 3. 2008-03-27. PMID:18094719. |
acute myeloid leukemia (aml) in down syndrome (ds) children has several unique features including a predominance of the acute megakaryocytic leukemia (amkl) phenotype, higher event-free survivals compared to non-ds children using cytosine arabinoside (ara-c)/anthracycline-based protocols and a uniform presence of somatic mutations in the x-linked transcription factor gene, gata1. |
2008-03-27 |
2023-08-12 |
Not clear |
| Erik Forestier, Shai Izraeli, Berna Beverloo, Oskar Haas, Andrea Pession, Kyra Michalová, Batia Stark, Christine J Harrison, Andrea Teigler-Schlegel, Bertil Johansso. Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study. Blood. vol 111. issue 3. 2008-03-26. PMID:17971484. |
children with down syndrome (ds) have a markedly increased risk of acute lymphoblastic leukemia (all) and acute myeloid leukemia (aml). |
2008-03-26 |
2023-08-12 |
Not clear |
| Johanna R Price, Joanne E Roberts, Elizabeth A Hennon, Mary C Berni, Kathleen L Anderson, John Sideri. Syntactic complexity during conversation of boys with fragile X syndrome and Down syndrome. Journal of speech, language, and hearing research : JSLHR. vol 51. issue 1. 2008-03-19. PMID:18230852. |
this study compared the syntax of boys who have fragile x syndrome (fxs) with and without autism spectrum disorder (asd) with that of (a) boys who have down syndrome (ds) and (b) typically developing (td) boys. |
2008-03-19 |
2023-08-12 |
Not clear |
| D Masjkey, S Bhattacharya, S Dhungel, C B Jha, S Shrestha, S R Ghimire, D Ra. Utility of phenotypic dermal indices in the detection of Down syndrome patients. Nepal Medical College journal : NMCJ. vol 9. issue 4. 2008-03-19. PMID:18298007. |
down syndrome (ds) is the most common cause of mental retardation. |
2008-03-19 |
2023-08-12 |
Not clear |
| Ronald H W Cheng, W Keung Leung, Esmonde F Corbe. Non-surgical periodontal therapy with adjunctive chlorhexidine use in adults with down syndrome: a prospective case series. Journal of periodontology. vol 79. issue 2. 2008-03-18. PMID:18251655. |
subjects with down syndrome (ds) experience a high prevalence of periodontal disease, and the management of this disease in subjects with ds is a challenge for oral health care providers. |
2008-03-18 |
2023-08-12 |
human |
| J M Biselli, E M Goloni-Bertollo, B L Zampieri, R Haddad, M N Eberlin, E C Pavarino-Bertell. Genetic polymorphisms involved in folate metabolism and elevated plasma concentrations of homocysteine: maternal risk factors for Down syndrome in Brazil. Genetics and molecular research : GMR. vol 7. issue 1. 2008-03-18. PMID:18273817. |
the aim of the present study was to investigate the effect of polymorphisms c677t and a1298c in the methylenetetrahydrofolate reductase (mthfr) gene, a2756g in methionine synthase reductase (mtr) gene and a80g in reduced folate carrier 1 (rfc1) gene, and plasma homocysteine (hcy), on the maternal risk for down syndrome (ds). |
2008-03-18 |
2023-08-12 |
Not clear |