| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elisa Fucà, Stefano Vicari, Floriana Costanz. Adaptive and Behavioral Profiles in Down Syndrome and Co-Occurring Autism Spectrum Disorder: A Case-Control Study. Autism research : official journal of the International Society for Autism Research. 2024-12-19. PMID:39698871. |
down syndrome (ds) is the most frequent genetic cause of intellectual disability (id). |
2024-12-19 |
2024-12-21 |
human |
| Savannah Tallino, Rachel Etebari, Ian McDonough, Hector Leon, Isabella Sepulveda, Wendy Winslow, Samantha K Bartholomew, Sylvia E Perez, Elliott J Mufson, Ramon Velazque. Assessing the Benefit of Dietary Choline Supplementation Throughout Adulthood in the Ts65Dn Mouse Model of Down Syndrome. Nutrients. vol 16. issue 23. 2024-12-17. PMID:39683562. |
down syndrome (ds) is the most common cause of early-onset alzheimer's disease (ad). |
2024-12-17 |
2024-12-21 |
mouse |
| Jamie Linert, Lizbeth H Finestack, Leonard Abbedut. Syntactic Growth of Adolescent Boys With Fragile X Syndrome or Down Syndrome: A Longitudinal Study. Journal of speech, language, and hearing research : JSLHR. 2024-12-16. PMID:39680808. |
the current study addresses a gap in the literature regarding syntactic development of adolescent boys with fragile x syndrome (fxs) and down syndrome (ds). |
2024-12-16 |
2024-12-21 |
Not clear |
| Tommaso Balestra, Lisa M Niswander, Asen Bagashev, Joseph P Loftus, Savannah L Ross, Robert K Chen, Samantha M McClellan, Jacob J Junco, Diego A Bárcenas López, Karen R Rabin, Terry J Fry, Sarah K Tasia. Co-targeting of the thymic stromal lymphopoietin receptor to decrease immunotherapeutic resistance in CRLF2-rearranged Ph-like and Down syndrome acute lymphoblastic leukemia. Leukemia. 2024-12-16. PMID:39681640. |
crlf2 rearrangements occur in >50% of ph-like and down syndrome (ds)-associated b-acute lymphoblastic leukemia (all) and induce constitutive kinase signaling targetable by the jak1/2 inhibitor ruxolitinib under current clinical investigation. |
2024-12-16 |
2024-12-21 |
mouse |
| Kirby M Sherman, Catrina J Silveira, Mingquan Yan, Ling Yu, Abigail Leon, Kasey Klages, Lauren G White, Hannah M Smith, Sarah M Wolff, Alyssa Falck, Ken Muneoka, Regina Brunauer, Dana Gaddy, Larry J Suva, Lindsay A Dawso. Male Down syndrome Ts65Dn mice have impaired bone regeneration. Bone. 2024-12-15. PMID:39675408. |
to determine the bone regenerative capacity of down syndrome (ds) mice, male and female dp16 and ts65dn ds mice underwent amputation of the digit tip (the terminal phalanx (p3)). |
2024-12-15 |
2024-12-21 |
mouse |
| Brett S Nickerson, Michael R Esco, George Schaefer, Elroy J Aguiar, Stefan A Czerwinsk. A descriptive analysis of sarcopenia markers in young adults with down syndrome. Experimental gerontology. vol 199. 2024-12-14. PMID:39667712. |
most body composition research in individuals with down syndrome (ds) has focused on overweight and obesity. |
2024-12-14 |
2024-12-21 |
Not clear |
| Lucas A Gillenwater, Matthew D Galbraith, Angela L Rachubinski, Neetha Paul Eduthan, Kelly D Sullivan, Joaquin M Espinosa, James C Costell. Integrated analysis of immunometabolic interactions in Down syndrome. Science advances. vol 10. issue 50. 2024-12-13. PMID:39671500. |
down syndrome (ds), caused by trisomy 21 (t21), results in immune and metabolic dysregulation. |
2024-12-13 |
2024-12-21 |
Not clear |
| Elizabeth Chorvinsky, Surajit Bhattacharya, Betelehem Solomon Bera, Allison Welham, Karim Ismat, Claire M Lawlor, Diego Preciado, Jose L Gomez, Hiroki Morizono, Dinesh K Pillai, Maria J Gutierrez, Jyoti K Jaiswal, Gustavo Nin. Dysregulated airway epithelial antiviral immunity in Down Syndrome impairs type III IFN response and amplifies airway inflammation during RSV infection. bioRxiv : the preprint server for biology. 2024-12-09. PMID:39651190. |
trisomy 21 (ts21), also known as down syndrome (ds), increases pediatric mortality risk from respiratory syncytial virus (rsv) by nine-fold, yet its underlying immunological basis remains unclear. |
2024-12-09 |
2024-12-12 |
Not clear |
| Mitsuhiro Masaki, Yuka Iizuka, Karin Sugawara, Yuki Uchikawa, Honoka Isobe, Fuyumi Hattori, Koki Mano, Keiko Saito, Ayaka Sugino, Kana Kato, Kenji Sakain. Association of walking and activities of daily living with muscle thickness of the trunk and lower extremity muscles in children with down syndrome. Developmental neurorehabilitation. 2024-12-09. PMID:39651966. |
we examined the association of walking and activities of daily living(adl) with trunk and lower extremity muscle thickness in children with down syndrome (ds). |
2024-12-09 |
2024-12-12 |
Not clear |
| Weili Shi, Shixiu Lia. [Research progress on the cognitive deficit of Down syndrome patients]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 41. issue 12. 2024-12-09. PMID:39653359. |
as the most common chromosomal disorder compatible to life, down syndrome (ds) is caused by an extra copy of chromosome 21. |
2024-12-09 |
2024-12-12 |
Not clear |
| Atsushi Kohso, Hidemi Toyoda, Ryo Hanaki, Kaori Niwa, Yosuke Okumura, Mari Morimoto, Takahiro Ito, Masahiro Hirayam. Inotuzumab ozogamicin for relapse prevention in a boy with Down syndrome and relapsed acute lymphoblastic leukemia. International journal of hematology. 2024-12-08. PMID:39648271. |
children with down syndrome (ds) have an increased risk of bcp-all and higher rates of relapse and toxicity, including treatment-related mortality. |
2024-12-08 |
2024-12-11 |
Not clear |
| Jingjing Zhang, Yuuya Kohzuka, Kathleen M Bennett, Fernanda R Almeid. Case reports of oral appliance therapy on three young adults with Down syndrome and OSA. Journal of prosthodontics : official journal of the American College of Prosthodontists. 2024-12-04. PMID:39632349. |
patients with down syndrome (ds) have a high incidence of obstructive sleep apnea (osa) due to hypotonia, weight, underdeveloped midface, and relative macroglossia. |
2024-12-04 |
2024-12-07 |
Not clear |
| Sara R Sherman, Ronald Jackson, Natalia S Lima, Brooks A Hibner, Bo Fernhall, Tracy Baynar. Blunted Exercise Pressor Response to Isometric Knee Extension and Post Exercise Ischemia in Individuals with Down Syndrome. Medicine and science in sports and exercise. 2024-12-03. PMID:39625363. |
individuals with down syndrome (ds) exhibit autonomic dysfunction, which contributes to reduced work capacity. |
2024-12-03 |
2024-12-06 |
Not clear |
| Sanae Yamazaki, Jun Miyauchi, Hideaki Sato, Yuko Takahashi, Takayuki Amikur. Autopsy case of a stillbirth with transient abnormal myelopoiesis associated with Down syndrome: Immunohistochemical demonstration of GATA1 mutation in placental tissues. Pathology international. 2024-12-02. PMID:39620384. |
transient abnormal myelopoiesis (tam) in neonates with down syndrome (ds) exhibits hematological features that are indistinguishable from those of acute megakaryoblastic leukemia. |
2024-12-02 |
2024-12-06 |
Not clear |
| Ahmed Nageeb Mahmoud, John Paul Prodoehl, Maria F Echeverry-Martinez, Daniel S Horwit. Hemiarthroplasty for Hip Fracture in Down Syndrome: A Retrospective Series of Five Cases. Hip & pelvis. vol 36. issue 4. 2024-12-02. PMID:39620569. |
there is limited evidence regarding the outcomes of hip hemiarthroplasty (ha) following trauma in individuals living with down syndrome (ds). |
2024-12-02 |
2024-12-06 |
Not clear |
| Michael J Foster, Jeffrey Chu, Jacqueline Shaia, Rishi P Singh, Katherine E Talcot. Prevalence and diversity of retinal disease in adults with Down syndrome. Eye (London, England). 2024-11-29. PMID:39613904. |
while epidemiologic data exists for some ophthalmic diseases in people with down syndrome (ds), like strabismus and amblyopia, no studies explore the prevalence of retinal disease in people with ds on a large scale. |
2024-11-29 |
2024-12-02 |
Not clear |
| Michael J Foster, Jeffrey Chu, Jacqueline Shaia, Rishi P Singh, Katherine E Talcot. Prevalence and diversity of retinal disease in adults with Down syndrome. Eye (London, England). 2024-11-29. PMID:39613904. |
to evaluate previous studies on physiology and/or anatomy in retinal models representing ds or in the retinas of people with ds, all relevant terms related to down syndrome, retina, and retinal diseases were searched in pubmed and scopus. |
2024-11-29 |
2024-12-02 |
Not clear |
| Melissa J Alldred, Kyrillos W Ibrahim, Harshitha Pidikiti, Gabriela Chiosis, Elliott J Mufson, Grace E Stutzmann, Stephen D Ginsber. Down syndrome frontal cortex layer III and layer V pyramidal neurons exhibit lamina specific degeneration in aged individuals. Acta neuropathologica communications. vol 12. issue 1. 2024-11-28. PMID:39605035. |
selective vulnerability of neuronal populations occurs in both down syndrome (ds) and alzheimer's disease (ad), resulting in disproportional degeneration of pyramidal neurons (pns) affecting memory and executive function. |
2024-11-28 |
2024-11-30 |
human |
| Stephanie L Santoro, Ayesha Harisinghani, Caroline Bregman, Clorinda Cottrell, Margaret B Pulsifer, Mikayla Shaffer, Amy Torres, Brian G Skotko, Nicolas M Oreskovi. Implementing a Quality Improvement Initiative to Screen for Dementia in a Down Syndrome Specialty Clinic. American journal of medical genetics. Part A. 2024-11-28. PMID:39607288. |
using quality improvement methods, we aimed to implement a protocol to assess for dementia among adults with down syndrome (ds). |
2024-11-28 |
2024-11-30 |
Not clear |
| Letícia Abdelnour Zuanon, Juliana Dela Líbera, João Victor Soares Rodrigues, Pedro Henrique Petrilli, Alexia Ribeiro Horikawa, Márcio José Possari Dos Santos, Letícia Helena Theodoro, Karina Helga Leal Turci. Pressure pain threshold of the mastigatory muscles and reaction to touch in adults with down syndrome and neurotypicals: cross-sectional study. Journal of bodywork and movement therapies. vol 40. 2024-11-27. PMID:39593493. |
down syndrome (ds) is currently the most common chromosomal condition associated with intellectual disability in the global population and is characterized by a variety of additional clinical findings. |
2024-11-27 |
2024-11-29 |
Not clear |