| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Renato Souza Oliveira, João Quadrado Gil, Andreia Rosa, Maria João Quadrado, Mauro Campo. Scheimpflug Tomographic Indices for Classifying Normal, Down Syndrome and Clinical Keratoconus in Pediatric Patients. Diagnostics (Basel, Switzerland). vol 14. issue 17. 2024-09-14. PMID:39272718. |
the study aimed to evaluate the precision of different pentacam indices in diagnosing keratoconus (kc) in pediatric patients with and without down syndrome (ds) and determine suitable cutoff values. |
2024-09-14 |
2024-09-16 |
Not clear |
| b' A Bari\\xc5\\xa1i\\xc4\\x87, M Ergovi\\xc4\\x87 Ravan\\xc4\\x8di\\xc4\\x87, D Majstorovi\\xc4\\x87, J Vranekovi\\xc4\\x8. The Impact of the COVID-19 Pandemic on Individuals with Down Syndrome: A Croatian Survey. Balkan journal of medical genetics : BJMG. vol 27. issue 1. 2024-09-12. PMID:39263648.' |
among the most vulnerable groups in society are populations with multiple comorbidities, including individuals with down syndrome (ds). |
2024-09-12 |
2024-09-14 |
Not clear |
| Juliana Vieira de Barros Arcoverde, Carla Fernandes Dos Santos, Maria Cecília Magalhães Luckwu, Raysa Samanta Moraes Laranjeira, Aldianne Milene Dos Santos Barbosa, Thays Maria Costa de Lucena, Jaqueline de Azevêdo Silva, Neide Santo. Expression profile of inflammasome genes in individuals with Down syndrome. Genetics and molecular biology. vol 47. issue 4. 2024-09-12. PMID:39264098. |
down syndrome (ds), affecting 1 in 700 live births, is the most prevalent chromosomal disorder among newborns. |
2024-09-12 |
2024-09-14 |
human |
| Brigitte Fauroux, Silvia Sacco, Vincent Couloigner, Alessandro Amaddeo, Aimé Ravel, Emmanuelle Prioux, Jeanne Toulas, Cécile Cieuta-Walti, Hervé Walti, Romain Luscan, Ségolène Falquero, Manon Clert, Marie-Anne Caillaud, Livio De Sanctis, Sonia Khirani, Isabelle Marey, Clotilde Mirche. Early detection and treatment of obstructive sleep apnoea in infants with Down syndrome: a prospective, non-randomised, controlled, interventional study. The Lancet regional health. Europe. vol 45. 2024-09-12. PMID:39262447. |
infants with down syndrome (ds) are at high risk of obstructive sleep apnoea (osa) which is associated with neurocognitive dysfunction and behaviour problems. |
2024-09-12 |
2024-09-14 |
Not clear |
| Maha Siddiqui, Sumaira Farooqui, Jaza Rizvi, Bashir Ahmed Soomro, Muhammad Usman Kha. Effects of Simulated Equestrian Therapy in Improving Motor Proficiency among Down Syndrome Children - A Randomized Controlled Trial. International journal of exercise science. vol 17. issue 1. 2024-09-11. PMID:39257644. |
this study was conducted at dar-ul-sukun institute and dr. ziauddin hospital from april to september 2023 by enrolling a total of 56 participants with down syndrome (ds) after obtaining informed, voluntary assent from the guardians of the participants. |
2024-09-11 |
2024-09-13 |
human |
| Beatriz Helena Brugnaro, Camila R G Lima, Isabelle G R DA Costa, Gesica Fernandes, Ana Carolina DE Campos, Peter Rosenbaum, Silvia Letícia Pavão, Nelci Adriana C F Roch. Personal and environmental factors and household assistance in Down syndrome: cross-sectional study. Anais da Academia Brasileira de Ciencias. vol 96. issue suppl 1. 2024-09-11. PMID:39258691. |
however, it is not known how these factors can impact independence in household chores in children/adolescents with down syndrome (ds). |
2024-09-11 |
2024-09-13 |
Not clear |
| Guillermo Cueto-Robledo, Ernesto Roldan-Valadez, Melissa Garcia-Lezama, Marisol Garcia-Cesar, Dulce-Iliana Navarro-Vergara, Maria-Berenice Torres-Roja. Updated review on pulmonary arterial hypertension: Differences between down syndrome and non-down syndrome populations. Current problems in cardiology. vol 49. issue 12. 2024-09-11. PMID:39260114. |
pulmonary arterial hypertension (pah) is a major concern in patients with down syndrome (ds) and congenital heart disease (chd). |
2024-09-11 |
2024-09-14 |
Not clear |
| Tan Huang, Sharida Fakurazi, Pike-See Cheah, King-Hwa Lin. Chromosomal and cellular therapeutic approaches for Down syndrome: A research update. Biochemical and biophysical research communications. vol 735. 2024-09-11. PMID:39260337. |
in individuals with down syndrome (ds), an additional hsa21 chromosome copy leads to the overexpression of a myriad of hsa21 genes, disrupting the transcription of the entire genome. |
2024-09-11 |
2024-09-14 |
human |
| Daniel Miezah, Melanie Porter, Jennifer Batchelor, Poli Gavria, Kelsie Boulton, Jessica Reev. Everyday Executive Functioning Profiles in Adults with Down Syndrome. Journal of autism and developmental disorders. 2024-09-09. PMID:39249575. |
research on everyday executive functions in individuals with down syndrome (ds) has focused mostly on children and adolescents. |
2024-09-09 |
2024-09-11 |
Not clear |
| Angela John Thurman, Amanda Dimachkie Nunnally, Vivian Nguyen, Elizabeth Berry-Kravis, Audra Sterling, Jamie Edgin, Debra Hamilton, Jeannie Aschkenasy, Leonard Abbedut. Short-term and Long-term Stability of the Autism Diagnostic Observation Schedule (ADOS-2) Calibrated Comparison Scores (CCS) and Classification Scores in Youth with Down Syndrome or Fragile X Syndrome with Intellectual Disability. Journal of autism and developmental disorders. 2024-09-09. PMID:39251531. |
autism diagnosis in individuals with fragile x syndrome (fxs) or down syndrome (ds) with co-occurring intellectual disability is complex since clinicians often must consider other co-occurring behavioral features. |
2024-09-09 |
2024-09-13 |
Not clear |
| Federico Bellelli, Ernesto Consorti, Sara Garlini, Fabio Recalcati, Marco Froldi, Marco Proietti, Matteo Cesar. Frailty in Persons With Down Syndrome: Results From the REVIVIS Study. Journal of the American Medical Directors Association. 2024-09-07. PMID:39243800. |
to determine frailty prevalence and identify possible nonclinical factors associated with this condition in community-dwelling individuals with down syndrome (ds). |
2024-09-07 |
2024-09-10 |
Not clear |
| Weili Shi, Rui Chen, Mingjie Zhou, Yunian Li, Yuwei Zhang, Jikui Wang, Bingtao Hao, Shixiu Lia. Methyltransferase METTL3 governs the modulation of SH3BGR expression through m6A methylation modification, imparting influence on apoptosis in the context of Down syndrome-associated cardiac development. Cell death discovery. vol 10. issue 1. 2024-09-05. PMID:39237501. |
down syndrome (ds), caused by an additional chromosome 21, has a high risk of congenital heart defects (chd), one of the primary causes of mortality in ds newborns. |
2024-09-05 |
2024-09-08 |
mouse |
| Weili Shi, Rui Chen, Mingjie Zhou, Yunian Li, Yuwei Zhang, Jikui Wang, Bingtao Hao, Shixiu Lia. Methyltransferase METTL3 governs the modulation of SH3BGR expression through m6A methylation modification, imparting influence on apoptosis in the context of Down syndrome-associated cardiac development. Cell death discovery. vol 10. issue 1. 2024-09-05. PMID:39237501. |
to elucidate the pathogenetic mechanisms underlying this condition, we explored the role of rna m6a methylation, regulated by mettl3, in ds cardiac development and its impact on the expression of sh3bgr, a gene located at down syndrome congenital heart disease (ds-chd) minimal region. |
2024-09-05 |
2024-09-08 |
mouse |
| Fergus Edward Cheok, Natania Rae Xiangqin Tan, Yu Yi Chan, Bryan Wei Zhi Wong, Gwyneth Kong, Zubair Amin, Yvonne Peng Mei N. Quality of life of family caregivers of children and young adults with Down syndrome: A systematic review and meta-analysis. Annals of the Academy of Medicine, Singapore. vol 53. issue 8. 2024-09-04. PMID:39230317. |
the aims of this systematic review and meta-analysis are to synthesise quality of life (qol) of family caregivers of children and young adults with down syndrome (ds) and determine factors affecting their qol. |
2024-09-04 |
2024-09-06 |
Not clear |
| Yu Yi Chan, Bryan Wei Zhi Wong, Fergus Edward Cheok, Natania Rae Xiangqin Tan, Gwyneth Kong, Zubair Amin, Yvonne Peng Mei N. Quality of life of children and young adults with Down syndrome from caregivers' perspective: A systematic review and meta-analysis. Annals of the Academy of Medicine, Singapore. vol 53. issue 8. 2024-09-04. PMID:39230318. |
down syndrome (ds) negatively impacts the well-being of affected individuals. |
2024-09-04 |
2024-09-06 |
Not clear |
| Hideomi Takizawa, Masahiro Takahashi, Hiroshi Yoshida, Tetsutaro Yamaguchi, Koutaro Mak. Three-dimensional assessment of the nasopharyngeal airway in Down syndrome during the mixed dentition period: a case-control study. The Angle orthodontist. 2024-09-03. PMID:39223719. |
in this retrospective case-control study, we aimed to evaluate the nasopharyngeal airway volume of children with down syndrome (ds) and compare the results with those of control participants well matched for sex and age. |
2024-09-03 |
2024-09-05 |
human |
| Angela L Rachubinski, Lina R Patel, Elise M Sannar, Ryan M Kammeyer, Jessica Sanders, Belinda A Enriquez-Estrada, Kayleigh R Worek, Deborah J Fidler, Jonathan D Santoro, Joaquin M Espinos. JAK inhibition in Down Syndrome Regression Disorder. Journal of neuroimmunology. vol 395. 2024-08-31. PMID:39216159. |
down syndrome regression disorder (drsd) is an uncommon but devastating condition affecting primarily adolescents and young adults with down syndrome (ds). |
2024-08-31 |
2024-09-04 |
Not clear |
| Amina Triki, Rihab Borji, Rabeb Laatar, Sonia Sahli, Haithem Reba. The effect of dual-task training on postural and cognitive performances in adolescents with down syndrome. Research in developmental disabilities. vol 153. 2024-08-31. PMID:39216176. |
therefore, it seems of interest to explore the effect of such training modality in individuals with down syndrome (ds) presenting both cognitive and postural deficits. |
2024-08-31 |
2024-09-04 |
Not clear |
| Emily K Schworer, Matthew D Zammit, Jiebiao Wang, Benjamin L Handen, Tobey Betthauser, Charles M Laymon, Dana L Tudorascu, Annie D Cohen, Shahid H Zaman, Beau M Ances, Mark Mapstone, Elizabeth Head, William E Klunk, Bradley T Christian, Sigan L Hartle. Amyloid age and tau PET timeline to symptomatic Alzheimer's disease in Down syndrome. medRxiv : the preprint server for health sciences. 2024-08-30. PMID:39211859. |
adults with down syndrome (ds) are at risk for alzheimer's disease (ad). |
2024-08-30 |
2024-09-04 |
Not clear |
| Hannah Saternos, Eric D Hamlett, Samuel Guzman, Elizabeth Head, Ann-Charlotte Granholm, Aurélie Ledreu. Unique Pathology in the Locus Coeruleus of Individuals with Down Syndrome. Journal of Alzheimer's disease : JAD. 2024-08-30. PMID:39213062. |
down syndrome (ds) is one of the most commonly occurring chromosomal conditions. |
2024-08-30 |
2024-09-04 |
Not clear |