| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Sitz, K Baumgärtel, B Hämmerle, C Papadopoulos, P Hekerman, F J Tejedor, W Becker, B Lut. The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4. Neuroscience. vol 157. issue 3. 2009-04-14. PMID:18938227. |
dyrk1a is overexpressed in down syndrome (ds) and has recently been implicated in several neurodegenerative diseases. |
2009-04-14 |
2023-08-12 |
mouse |
| Frances K Wiseman, Kate A Alford, Victor L J Tybulewicz, Elizabeth M C Fishe. Down syndrome--recent progress and future prospects. Human molecular genetics. vol 18. issue R1. 2009-04-14. PMID:19297404. |
down syndrome (ds) is caused by trisomy of chromosome 21 (hsa21) and is associated with a number of deleterious phenotypes, including learning disability, heart defects, early-onset alzheimer's disease and childhood leukaemia. |
2009-04-14 |
2023-08-12 |
mouse |
| Joachim Höger, David Patterson, Harald Höger, Ki-Shuk Shim, Hermann Bubna-Littitz, Gert Lube. Mice transgenic for reduced folate carrier: an animal model of Down syndrome? Amino acids. vol 36. issue 2. 2009-04-10. PMID:18414976. |
in a previous publication we observed aberrant levels of the human reduced folate carrier (hrfc) in cortex from fetal down syndrome (ds) subjects. |
2009-04-10 |
2023-08-12 |
mouse |
| Randall J Roper, Justin F VanHorn, Colyn C Cain, Roger H Reeve. A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog. Mechanisms of development. vol 126. issue 3-4. 2009-04-10. PMID:19056491. |
trisomy 21 results in phenotypes collectively referred to as down syndrome (ds) including characteristic facial dysmorphology. |
2009-04-10 |
2023-08-12 |
mouse |
| Catherine L Carmichael, Ian J Majewski, Warren S Alexander, Donald Metcalf, Douglas J Hilton, Chelsee A Hewitt, Hamish S Scot. Hematopoietic defects in the Ts1Cje mouse model of Down syndrome. Blood. vol 113. issue 9. 2009-04-10. PMID:19109561. |
down syndrome (ds) persons are born with various hematopoietic abnormalities, ranging from relatively benign, such as neutrophilia and macrocytosis, to a more severe transient myeloproliferative disorder (tmd). |
2009-04-10 |
2023-08-12 |
mouse |
| A Siddiqui, T Lacroix, M R Stasko, J J Scott-McKean, A C S Costa, K J Gardine. Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801. Genes, brain, and behavior. vol 7. issue 7. 2009-04-10. PMID:19125866. |
down syndrome (ds), caused by trisomy of human chromosome 21 (chr21), is the most common genetic cause of intellectual disability. |
2009-04-10 |
2023-08-12 |
mouse |
| S Basu, V Pooniya, A Kumar, B K Da. Down syndrome with cerebral arteriovenous malformation. Annals of tropical paediatrics. vol 29. issue 1. 2009-04-07. PMID:19222937. |
down syndrome (ds) or trisomy 21 is one of the most common and best known of all chromosomal disorders. |
2009-04-07 |
2023-08-12 |
Not clear |
| Simona Ognjanovic, Susan Puumala, Logan G Spector, Franklin O Smith, Leslie L Robison, Andrew F Olshan, Julie A Ros. Maternal health conditions during pregnancy and acute leukemia in children with Down syndrome: A Children's Oncology Group study. Pediatric blood & cancer. vol 52. issue 5. 2009-04-06. PMID:19148952. |
children with down syndrome (ds) have about a 20-fold increased risk of developing leukemia. |
2009-04-06 |
2023-08-12 |
Not clear |
| Miguel Galeote, Pilar Soto, Elena Checa, Aurora Gómez, Elena Lamel. The acquisition of productive vocabulary in Spanish children with Down syndrome. Journal of intellectual & developmental disability. vol 33. issue 4. 2009-04-01. PMID:19039689. |
it is generally assumed that children with down syndrome (ds) present a deficit in lexical production relative to their cognitive abilities. |
2009-04-01 |
2023-08-12 |
Not clear |
| Karen Caplovitz Barrett, Deborah J Fidle. Tonguing behaviours in persons with Down syndrome: moderator of the effects of negative mood on behaviour problems. Journal of intellectual & developmental disability. vol 33. issue 4. 2009-04-01. PMID:19039690. |
there is concern that tongue protrusion may be maladaptive in individuals with down syndrome (ds). |
2009-04-01 |
2023-08-12 |
Not clear |
| Ewa Barg, Marta Bury, Tomasz Marczyk, Katarzyna Pałac, Magdalena Wirt. [Psychosexual problem in young people with Down syndrome in parents' opinions - personal experience]. Pediatric endocrinology, diabetes, and metabolism. vol 14. issue 4. 2009-03-31. PMID:19239790. |
down syndrome (ds) is a genetic disorder affecting psychomotor and psychosexual development connected with mental retardation and endocrine disorders. |
2009-03-31 |
2023-08-12 |
Not clear |
| V P Prasher, E Airuehia, A Patel, M S Haqu. Total serum cholesterol levels and Alzheimer's dementia in patients with Down syndrome. International journal of geriatric psychiatry. vol 23. issue 9. 2009-03-30. PMID:18395888. |
the risk for dementia in alzheimer's disease (dad) in adults with down syndrome (ds) is higher than in the general adult population. |
2009-03-30 |
2023-08-12 |
Not clear |
| Yoshiteru Kai, Chi Chiu Wang, Satoshi Kishigami, Yasuhiro Kazuki, Satoshi Abe, Masato Takiguchi, Yasuaki Shirayoshi, Toshiaki Inoue, Hisao Ito, Teruhiko Wakayama, Mitsuo Oshimur. Enhanced apoptosis during early neuronal differentiation in mouse ES cells with autosomal imbalance. Cell research. vol 19. issue 2. 2009-03-30. PMID:19015669. |
a common abnormal phenotype of down syndrome (ds), the most prevalent autosomal aneuploidy, shows a reduction in both the number and the density of neurons in the brain. |
2009-03-30 |
2023-08-12 |
mouse |
| Bo Fernhall, Tracy Baynard, Scott R Collier, Arturo Figueroa, Styliani Goulopoulou, Gary H Kamimori, Kenneth H Pitett. Catecholamine response to maximal exercise in persons with Down syndrome. The American journal of cardiology. vol 103. issue 5. 2009-03-27. PMID:19231341. |
individuals with down syndrome (ds) exhibit low peak aerobic capacities and heart rates. |
2009-03-27 |
2023-08-12 |
human |
| Gonçalo V Mendonça, Fernando D Pereira, Bo Fernhal. Walking economy in male adults with Down syndrome. European journal of applied physiology. vol 105. issue 1. 2009-03-26. PMID:18850109. |
the purpose of this study was to investigate walking economy in response to steady-state locomotion in adult males with down syndrome (ds) and in healthy controls. |
2009-03-26 |
2023-08-12 |
human |
| Monica Mohan, Peter K Carpenter, Cathy Bennet. Donepezil for dementia in people with Down syndrome. The Cochrane database of systematic reviews. issue 1. 2009-03-19. PMID:19160328. |
alzheimer's dementia (ad) is the most common form of dementia in people with down syndrome [ds]. |
2009-03-19 |
2023-08-12 |
Not clear |
| Monica Mohan, Cathy Bennett, Peter K Carpente. Galantamine for dementia in people with Down syndrome. The Cochrane database of systematic reviews. issue 1. 2009-03-19. PMID:19160342. |
alzheimer's dementia (ad) is the most common form of dementia in people with down syndrome (ds). |
2009-03-19 |
2023-08-12 |
Not clear |
| Monica Mohan, Cathy Bennett, Peter K Carpente. Memantine for dementia in people with Down syndrome. The Cochrane database of systematic reviews. issue 1. 2009-03-19. PMID:19160343. |
alzheimer's dementia (ad) is the most common form of dementia in people with down syndrome (ds). |
2009-03-19 |
2023-08-12 |
human |
| Monica Mohan, Cathy Bennett, Peter K Carpente. Rivastigmine for dementia in people with Down syndrome. The Cochrane database of systematic reviews. issue 1. 2009-03-19. PMID:19160344. |
alzheimer's dementia (ad) is the most common form of dementia in people with down syndrome (ds). |
2009-03-19 |
2023-08-12 |
Not clear |
| Ning Ma, Rui-Fang Niu, Yong-Jie M. Intersectin 1: a molecular linker in the central nervous system. Neuroscience bulletin. vol 24. issue 6. 2009-03-17. PMID:19037327. |
down syndrome (ds) is the most common cause of cognitive impairment associated with a congenital chromosomal abnormality, trisomy of chromosome 21. |
2009-03-17 |
2023-08-12 |
human |