| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lyndal Kearney, David Gonzalez De Castro, Jenny Yeung, Julia Procter, Sharon W Horsley, Minenori Eguchi-Ishimae, Caroline M Bateman, Kristina Anderson, Tracy Chaplin, Bryan D Young, Christine J Harrison, Helena Kempski, Chi Wai E So, Anthony M Ford, Mel Greave. Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia. Blood. vol 113. issue 3. 2009-02-17. PMID:18927438. |
children with down syndrome (ds) have a greatly increased risk of acute megakaryoblastic leukemia (amkl) and acute lymphoblastic leukemia (all). |
2009-02-17 |
2023-08-12 |
Not clear |
| Marcia R Amorim, Crisiane Wais Zanrosso, Isis Q Magalhães, Simone C Pereira, Alexandre Figueiredo, Mariana Emerenciano, Vitoria Regia Pinheiro, Maria Lydia d'Andréa, Ieda M Orioli, Sergio Koifman, Maria S Pombo-de-Oliveir. MTHFR 677C-->T and 1298A-->C polymorphisms in children with Down syndrome and acute myeloid leukemia in Brazil. Pediatric hematology and oncology. vol 25. issue 8. 2009-02-17. PMID:19065440. |
down syndrome (ds) is an important risk factor associated with acute leukemia (al). |
2009-02-17 |
2023-08-12 |
Not clear |
| Karen Bonde Larsen, Henning Laursen, Niels Graem, Grethe Badsberg Samuelsen, Nenad Bogdanovic, Bente Pakkenber. Reduced cell number in the neocortical part of the human fetal brain in Down syndrome. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 190. issue 5. 2009-02-13. PMID:18722098. |
mental retardation is seen in all individuals with down syndrome (ds) and different brain abnormalities are reported. |
2009-02-13 |
2023-08-12 |
human |
| D S Sulemanji, A Donmez, E A Akpek, Y Ali. Vascular catheterization is difficult in infants with Down syndrome. Acta anaesthesiologica Scandinavica. vol 53. issue 1. 2009-02-12. PMID:19032563. |
our aim was to compare difficulties in vascular access interventions in infants with and without down syndrome (ds) undergoing congenital heart surgery. |
2009-02-12 |
2023-08-12 |
Not clear |
| Yong Yu, Po-Yin Chu, David N Bowser, Damien J Keating, Daphne Dubach, Ian Harper, Josephine Tkalcevic, David I Finkelstein, Melanie A Pritchar. Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities. Human molecular genetics. vol 17. issue 21. 2009-02-10. PMID:18676989. |
enlarged early endosomes in the neurons of young down syndrome (ds) and pre-alzheimer's disease (ad) brains suggest that a disturbance in endocytosis is one of the earliest hallmarks of ad pathogenesis in both conditions. |
2009-02-10 |
2023-08-12 |
mouse |
| Jeroen Wouters, Michel E Weijerman, A Marceline van Furth, Marco W J Schreurs, J Bart A Crusius, B Mary E von Blomberg, Laura R de Baaij, Chantal J M Broers, Reinoud J B J Gemk. Prospective human leukocyte antigen, endomysium immunoglobulin A antibodies, and transglutaminase antibodies testing for celiac disease in children with Down syndrome. The Journal of pediatrics. vol 154. issue 2. 2009-02-10. PMID:18822429. |
to assess the effect of a prospective screening strategy for the early diagnosis of celiac disease (cd) in children with down syndrome (ds). |
2009-02-10 |
2023-08-12 |
human |
| Pavel V Belichenko, Alexander M Kleschevnikov, Eliezer Masliah, Chengbiao Wu, Ryoko Takimoto-Kimura, Ahmad Salehi, William C Moble. Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome. The Journal of comparative neurology. vol 512. issue 4. 2009-02-09. PMID:19034952. |
down syndrome (ds) is a neurological disorder causing impaired learning and memory. |
2009-02-09 |
2023-08-12 |
mouse |
| Julie-Anne Little, J Margaret Woodhouse, Jan S Lauritzen, Kathryn J Saunder. Vernier acuity in Down syndrome. Investigative ophthalmology & visual science. vol 50. issue 2. 2009-02-06. PMID:18824732. |
down syndrome (ds) is associated with reduced visual performance. |
2009-02-06 |
2023-08-12 |
Not clear |
| T Toki, R Kanezaki, S Adachi, H Fujino, G Xu, T Sato, K Suzuki, H Tauchi, M Endo, E It. The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia. Leukemia. vol 23. issue 1. 2009-02-06. PMID:18830255. |
transient leukemia (tl) has been observed in approximately 10% of newborn infants with down syndrome (ds). |
2009-02-06 |
2023-08-12 |
Not clear |
| C B Santos-Rebouças, J C Corrêa, A Bonomo, N Fintelman-Rodrigues, K C V Moura, C S C Rodrigues, J M Santos, M M G Pimente. The impact of folate pathway polymorphisms combined to nutritional deficiency as a maternal predisposition factor for Down syndrome. Disease markers. vol 25. issue 3. 2009-02-04. PMID:19096127. |
with the purpose of evaluating this relationship, we compared the frequencies of 677c>t and 1298a>c polymorphisms in the methylenetetrahydrofolate reductase gene (mthfr) and 66a>g in the methionine synthase reductase gene (mtrr) between 103 young mothers of down syndrome (ds) individuals and 108 control mothers, whose offspring was karyotypically normal, correlating it with an estimative of folate and - related micronutrients levels intake. |
2009-02-04 |
2023-08-12 |
Not clear |
| G M Savva, J K Morri. Ascertainment and accuracy of Down syndrome cases reported in congenital anomaly registers in England and Wales. Archives of disease in childhood. Fetal and neonatal edition. vol 94. issue 1. 2009-02-03. PMID:18375610. |
we estimate the ascertainment and accuracy of records of down syndrome (ds) on national and regional registers in england and wales. |
2009-02-03 |
2023-08-12 |
Not clear |
| L Tiano, L Padella, P Carnevali, O Gabrielli, F Bruge, F Principi, G P Littarr. Coenzyme Q10 and oxidative imbalance in Down syndrome: biochemical and clinical aspects. BioFactors (Oxford, England). vol 32. issue 1-4. 2009-02-03. PMID:19096112. |
down syndrome (ds) is a chromosomal abnormality (trisomy 21) associated with mental retardation and alzheimer-like dementia, characteristic change of the individual's phenotype and premature ageing. |
2009-02-03 |
2023-08-12 |
Not clear |
| Ved Chauhan, Lina Ji, Abha Chauha. Anti-amyloidogenic, anti-oxidant and anti-apoptotic role of gelsolin in Alzheimer's disease. Biogerontology. vol 9. issue 6. 2009-02-02. PMID:18704746. |
fibrillar amyloid beta-protein (abeta) is a major component of amyloid plaques in the brains of individuals with alzheimer's disease (ad) and of adults with down syndrome (ds). |
2009-02-02 |
2023-08-12 |
mouse |
| X Altafaj, J Ortiz-Abalia, M Fernández, M C Potier, J Laffaire, N Andreu, M Dierssen, C González-García, V Ceña, E Martí, C Filla. Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome. Neurobiology of disease. vol 32. issue 3. 2009-01-28. PMID:18773961. |
transgenic mice overexpressing dyrk1a (tgdyrk1a), a down syndrome (ds) candidate gene, exhibit motor and cognitive alterations similar to those observed in ds individuals. |
2009-01-28 |
2023-08-12 |
mouse |
| Marcus T R Roofthooft, Hester van Meer, Wim G Rietman, Tjark Ebels, Rolf M F Berge. Down syndrome and aberrant right subclavian artery. European journal of pediatrics. vol 167. issue 9. 2009-01-22. PMID:18172685. |
down syndrome (ds) may be associated with various organ system disorders. |
2009-01-22 |
2023-08-12 |
Not clear |
| Alfredo G Linossier, Carlos Y Valenzuela, Héctor Toled. Differences of the oral colonization by Streptococcus of the mutans group in children and adolescents with Down syndrome, mental retardation and normal controls. Medicina oral, patologia oral y cirugia bucal. vol 13. issue 9. 2009-01-22. PMID:18758394. |
to compare the concentration and serotype of streptococcus mutans in saliva of down syndrome (ds), mental retarded (mr) and healthy control (c) individuals of the región metropolitana sur of santiago of chile. |
2009-01-22 |
2023-08-12 |
Not clear |
| Antonia M W Coppus, Heleen M Evenhuis, Gert-Jan Verberne, Frank E Visser, Ben A Oostra, Piet Eikelenboom, Willem A van Gool, A Cecile J W Janssens, Cornelia M van Duij. Survival in elderly persons with Down syndrome. Journal of the American Geriatrics Society. vol 56. issue 12. 2009-01-22. PMID:19093931. |
the longer life expectancy now experienced by persons with down syndrome (ds) makes it necessary to know the factors influencing survival in older persons with this syndrome. |
2009-01-22 |
2023-08-12 |
Not clear |
| E J Wortelboer, M P H Koster, Ph Stoutenbeek, J G Loeber, G H A Visser, P C J I Schiele. Fifteen years of triple tests in The Netherlands; the life cycle of a screening test. Prenatal diagnosis. vol 28. issue 10. 2009-01-13. PMID:18821712. |
this report provides an overview of 15 years prenatal screening for down syndrome (ds). |
2009-01-13 |
2023-08-12 |
Not clear |
| Oliver Tunstall-Pedoe, Anindita Roy, Anastasios Karadimitris, Josu de la Fuente, Nicholas M Fisk, Phillip Bennett, Alice Norton, Paresh Vyas, Irene Robert. Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations. Blood. vol 112. issue 12. 2009-01-12. PMID:18689547. |
down syndrome (ds) children have a high frequency of acute megakaryoblastic leukemia (amkl) in early childhood. |
2009-01-12 |
2023-08-12 |
Not clear |
| Catarina Lundin, Jesper Heldrup, Tomas Ahlgren, Tor Olofsson, Bertil Johansso. B-cell precursor t(8;14)(q11;q32)-positive acute lymphoblastic leukemia in children is strongly associated with Down syndrome or with a concomitant Philadelphia chromosome. European journal of haematology. vol 82. issue 1. 2009-01-12. PMID:19067745. |
there is a male preponderance, particularly in patients with down syndrome (ds) or in children with concomitant t(9;22)(q34;q11). |
2009-01-12 |
2023-08-12 |
Not clear |