| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alberto Goday-Arno, Mariaina Cerda-Esteva, Juana Antonia Flores-Le-Roux, Juan José Chillaron-Jordan, Josep Maria Corretger, Juan Francisco Cano-Pére. Hyperthyroidism in a population with Down syndrome (DS). Clinical endocrinology. vol 71. issue 1. 2009-10-13. PMID:18793345. |
thyroid disorders are frequent in patients with down syndrome (ds). |
2009-10-13 |
2023-08-12 |
Not clear |
| Martin Benesch, Andrea Moser, Petra Sovinz, Herwig Lackner, Wolfgang Schwinger, Hans Eder, Christian Urba. Medulloblastoma in a child with down syndrome: long-term remission with multimodality treatment. Pediatric blood & cancer. vol 53. issue 6. 2009-10-13. PMID:19489060. |
a 4(3/4)-year-old male with down syndrome (ds) presented with unsteady gait and fatigue. |
2009-10-13 |
2023-08-12 |
Not clear |
| Yuanxin Chen, Victor V Dyakin, Craig A Branch, Babak Ardekani, Dunsheng Yang, David N Guilfoyle, Jesse Peterson, Corrinne Peterhoff, Stephen D Ginsberg, Anne M Cataldo, Ralph A Nixo. In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model. Neurobiology of aging. vol 30. issue 9. 2009-10-09. PMID:18180075. |
in vivo quantitative magnetic resonance imaging (mri) was employed to detect brain pathology and map its distribution within control, disomic mice (2n) and in ts65dn and ts1cje trisomy mice with features of human down syndrome (ds). |
2009-10-09 |
2023-08-12 |
mouse |
| Floyd Sarsoza, Tommy Saing, Rakez Kayed, Robert Dahlin, Malcolm Dick, Camille Broadwater-Hollifield, Scott Mobley, Ira Lott, Eric Doran, Daniel Gillen, Clifford Anderson-Bergman, David H Cribbs, Charles Glabe, Elizabeth Hea. A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain. Acta neuropathologica. vol 118. issue 4. 2009-10-08. PMID:19360426. |
beta-amyloid (abeta) is thought to be a key contributor to the pathogenesis of alzheimer disease (ad) in the general population and in adults with down syndrome (ds). |
2009-10-08 |
2023-08-12 |
mouse |
| Harold L Kleinert, Carol A Lunney, Lynn Campbell, James E Ferguso. Improving residents' understanding of issues, comfort levels, and patient needs regarding screening for and diagnosing Down syndrome. American journal of obstetrics and gynecology. vol 201. issue 3. 2009-10-08. PMID:19631921. |
this study assessed obstetrics and gynecology and pediatrics residents' knowledge about down syndrome (ds) and their comfort in delivering a prenatal or postnatal diagnosis of ds before and after interaction with a web-based tutorial. |
2009-10-08 |
2023-08-12 |
Not clear |
| Julie-Anne Little, J Margaret Woodhouse, Kathryn J Saunder. Corneal power and astigmatism in Down syndrome. Optometry and vision science : official publication of the American Academy of Optometry. vol 86. issue 6. 2009-10-06. PMID:19390470. |
corneal and crystalline lens shape differ in down syndrome (ds) compared with developmentally normal populations. |
2009-10-06 |
2023-08-12 |
Not clear |
| S Lanfranchi, B Carretti, G Spanò, C Cornold. A specific deficit in visuospatial simultaneous working memory in Down syndrome. Journal of intellectual disability research : JIDR. vol 53. issue 5. 2009-09-30. PMID:19396941. |
recent studies have demonstrated that individuals with down syndrome (ds) present both central and verbal working memory deficits compared with controls matched for mental age, whereas evidence on visuospatial working memory (vswm) has remained ambiguous. |
2009-09-30 |
2023-08-12 |
Not clear |
| Priya S Kishnani, Barbara R Sommer, Benjamin L Handen, Benjamin Seltzer, George T Capone, Gail A Spiridigliozzi, James H Heller, Sharon Richardson, Thomas McRa. The efficacy, safety, and tolerability of donepezil for the treatment of young adults with Down syndrome. American journal of medical genetics. Part A. vol 149A. issue 8. 2009-09-30. PMID:19606472. |
the objective of our study was to assess the efficacy and safety of donepezil in young adults with down syndrome (ds) but no evidence of alzheimer disease (ad). |
2009-09-30 |
2023-08-12 |
human |
| Claudio Babiloni, Giorgio Albertini, Paolo Onorati, Fabrizio Vecchio, Paola Buffo, Marco Sarà, Claudia Condoluci, Francesca Pistoia, Filippo Carducci, Paolo M Rossin. Inter-hemispheric functional coupling of eyes-closed resting EEG rhythms in adolescents with Down syndrome. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 120. issue 9. 2009-09-23. PMID:19643663. |
we tested the hypothesis that inter-hemispheric directional functional coupling of eyes-closed resting eeg rhythms is abnormal in adolescents with down syndrome (ds). |
2009-09-23 |
2023-08-12 |
Not clear |
| b' J Flores-Lujano, M L Perez-Saldivar, E M Fuentes-Panan\\xc3\\xa1, C Gorodezky, R Bernaldez-Rios, M A Del Campo-Martinez, A Martinez-Avalos, A Medina-Sanson, R Paredes-Aguilera, J De Diego-Flores Chapa, V Bolea-Murga, M C Rodriguez-Zepeda, R Rivera-Luna, M A Palomo-Colli, L Romero-Guzman, P Perez-Vera, M Alvarado-Ibarra, F Salamanca-G\\xc3\\xb3mez, A Fajardo-Gutierrez, J M Mej\\xc3\\xada-Arangur\\xc3\\xa. Breastfeeding and early infection in the aetiology of childhood leukaemia in Down syndrome. British journal of cancer. vol 101. issue 5. 2009-09-18. PMID:19707206.' |
for a child to develop acute leukaemia (al), environmental exposure may not be sufficient: interaction with a susceptibility factor to the disease, such as down syndrome (ds), may also be necessary. |
2009-09-18 |
2023-08-12 |
Not clear |
| Elizabeth Barnes, Joanne Roberts, Steven H Long, Gary E Martin, Mary C Berni, Kerry C Mandulak, John Sideri. Phonological accuracy and intelligibility in connected speech of boys with fragile X syndrome or Down syndrome. Journal of speech, language, and hearing research : JSLHR. vol 52. issue 4. 2009-09-17. PMID:19641081. |
to compare the phonological accuracy and speech intelligibility of boys with fragile x syndrome with autism spectrum disorder (fxs-asd), fragile x syndrome only (fxs-o), down syndrome (ds), and typically developing (td) boys. |
2009-09-17 |
2023-08-12 |
Not clear |
| Jeroen C Vis, Hanneke Thoonsen, Marielle G Duffels, Rianne A de Bruin-Bon, Sylvia A Huisman, Arie P van Dijk, Elke S Hoendermis, Rolf M Berger, Berto J Bouma, Barbara J Mulde. Six-minute walk test in patients with Down syndrome: validity and reproducibility. Archives of physical medicine and rehabilitation. vol 90. issue 8. 2009-09-15. PMID:19651279. |
to examine the validity of the six-minute walk test (6mwt) as a tool to evaluate functional exercise performance in patients with down syndrome (ds). |
2009-09-15 |
2023-08-12 |
Not clear |
| Marcia R Amorim, Alexandre B C Figueiredo, Alessandra Splendore, Isis Q Magalhães, Maria S Pombo-de-Oliveira, Kênia B El-Jaick, Maria Lydia D'andrea, Jozina Aquino, Dora Márcia Alencar, Silvia R Brandalise, Lilian Burlemaqui, Teresa Cristina Cardoso, Eni Guimarães Carvalho, Virginia M Coser, Imaruí Costa, Dolores Dorea, Mauricio Drumond, Venâncio Gomes Lopes, Núbia Mendonça, Maria Lucia M Lee, Luis Fernando Lopes, Carmen M Mendonça, Flávia Nogueira, Flávia Pimenta, Vitória P Pinheiro, Denise Bousfield Da Silva, Elaine Sobral, Fernando R Vargas, Fernando Wernec. Detection of mutations in GATA1 gene using automated denaturing high-performance liquid chromatography and direct sequencing in children with Down syndrome. Leukemia & lymphoma. vol 50. issue 5. 2009-08-27. PMID:19452320. |
in this study, we have evaluated the dhplc screening method and direct sequencing for the detection of gata1 mutations in peripheral blood and bone marrow aspirates samples from children with down syndrome (ds). |
2009-08-27 |
2023-08-12 |
Not clear |
| Kyung Ah Koo, Nam Doo Kim, Yong Sog Chon, Min-Su Jung, Burm-Jong Lee, Jung Ho Kim, Woo-Joo Son. QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitors. Bioorganic & medicinal chemistry letters. vol 19. issue 8. 2009-08-26. PMID:19282176. |
individuals with down syndrome (ds) suffer from mental retardation. |
2009-08-26 |
2023-08-12 |
mouse |
| David Patterso. Molecular genetic analysis of Down syndrome. Human genetics. vol 126. issue 1. 2009-08-25. PMID:19526251. |
down syndrome (ds) is caused by trisomy of all or part of human chromosome 21 (hsa21) and is the most common genetic cause of significant intellectual disability. |
2009-08-25 |
2023-08-12 |
mouse |
| Jan O Korbel, Tal Tirosh-Wagner, Alexander Eckehart Urban, Xiao-Ning Chen, Maya Kasowski, Li Dai, Fabian Grubert, Chandra Erdman, Michael C Gao, Ken Lange, Eric M Sobel, Gillian M Barlow, Arthur S Aylsworth, Nancy J Carpenter, Robin Dawn Clark, Monika Y Cohen, Eric Doran, Tzipora Falik-Zaccai, Susan O Lewin, Ira T Lott, Barbara C McGillivray, John B Moeschler, Mark J Pettenati, Siegfried M Pueschel, Kathleen W Rao, Lisa G Shaffer, Mordechai Shohat, Alexander J Van Riper, Dorothy Warburton, Sherman Weissman, Mark B Gerstein, Michael Snyder, Julie R Korenber. The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 29. 2009-08-25. PMID:19597142. |
down syndrome (ds), or trisomy 21, is a common disorder associated with several complex clinical phenotypes. |
2009-08-25 |
2023-08-12 |
human |
| Fabian Fernandez, Jonathan C Trinidad, Martina Blank, Dong-Dong Feng, Alma L Burlingame, Craig C Garne. Normal protein composition of synapses in Ts65Dn mice: a mouse model of Down syndrome. Journal of neurochemistry. vol 110. issue 1. 2009-08-21. PMID:19453946. |
down syndrome (ds) is the most prevalent form of intellectual disability caused by the triplication of approximately 230 genes on chromosome 21. |
2009-08-21 |
2023-08-12 |
mouse |
| Mara Dierssen, Yann Herault, Xavier Estivil. Aneuploidy: from a physiological mechanism of variance to Down syndrome. Physiological reviews. vol 89. issue 3. 2009-08-20. PMID:19584316. |
in this review, we focus on down syndrome (ds) as the prototype of "genomic disorder" induced by copy number change. |
2009-08-20 |
2023-08-12 |
mouse |
| Heiko Reutter, Arend Bökenkamp, Anne-Karolin Ebert, Wolfgang Rösch, Thomas M Boemers, Markus M Nöthen, Michael Ludwi. Possible association of Down syndrome and exstrophy-epispadias complex: report of two new cases and review of the literature. European journal of pediatrics. vol 168. issue 7. 2009-08-19. PMID:18923839. |
in the past, several midline defects have been associated with down syndrome (ds) on a regular basis, e.g. |
2009-08-19 |
2023-08-12 |
Not clear |
| A Myrelid, B Jonsson, C Guthenberg, U von Döbeln, G Annerén, J Gustafsso. Increased neonatal thyrotropin in Down syndrome. Acta paediatrica (Oslo, Norway : 1992). vol 98. issue 6. 2009-08-19. PMID:19239410. |
down syndrome (ds) is frequently associated with thyroid dysfunction. |
2009-08-19 |
2023-08-12 |
Not clear |