| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E J Wortelboer, I H Linskens, M P H Koster, P Stoutenbeek, H Cuckle, M A Blankenstein, G H A Visser, J M G van Vugt, P C J I Schiele. ADAM12s as a first-trimester screening marker of trisomy. Prenatal diagnosis. vol 29. issue 9. 2009-12-14. PMID:19544290. |
to evaluate the potential of maternal serum a disintegrin and metalloprotease 12-s (adam12s) as an additional marker for the combined test in the dutch first-trimester national down syndrome (ds) screening program. |
2009-12-14 |
2023-08-12 |
Not clear |
| Ira T Lott, Eric Doran, David M Walsh, Mary Ann Hil. Telemedicine, dementia and Down syndrome: implications for Alzheimer disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 2. issue 3. 2009-12-14. PMID:19595881. |
individuals with down syndrome (ds) who are at risk for dementia of the alzheimer type (dat) often live at sites remote from major medical centers. |
2009-12-14 |
2023-08-12 |
Not clear |
| Frédéric Delom, Emma Burt, Alex Hoischen, Joris Veltman, Jürgen Groet, Finbarr E Cotter, Dean Nizeti. Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix. Proteome science. vol 7. 2009-12-11. PMID:19715584. |
down syndrome (ds), caused by trisomy of human chromosome 21 (hsa21), is the most common genetic birth defect. |
2009-12-11 |
2023-08-12 |
human |
| Fumiko Yamato, Junji Takaya, Akihiro Yasuhara, Masayuki Teraguchi, Yumiko Ikemoto, Kazunari Kanek. Elevated intracellular calcium in neutrophils in patients with Down syndrome. Pediatrics international : official journal of the Japan Pediatric Society. vol 51. issue 4. 2009-12-09. PMID:19400826. |
neutrophils of patients with down syndrome (ds) are known to have numerous abnormalities associated with diminished resistance to infection. |
2009-12-09 |
2023-08-12 |
human |
| Alberto C S Costa, Melissa R Stasko, Cecilia Schmidt, Muriel T Davisso. Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pde6b(rd1). Behavioural brain research. vol 206. issue 1. 2009-12-09. PMID:19720087. |
the ts65dn mouse is the most studied and complete aneuploid model of down syndrome (ds) widely available. |
2009-12-09 |
2023-08-12 |
mouse |
| b' Lucia Migliore, Francesca Migheli, Fabio Copped\\xc3\\xa. Susceptibility to aneuploidy in young mothers of Down syndrome children. TheScientificWorldJournal. vol 9. 2009-12-02. PMID:19802501.' |
we recently observed an increased frequency of binucleated micronucleated lymphocytes in women who had a down syndrome (ds) child before 35 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from chromosomal malsegregation events, including chromosome 21 malsegregation. |
2009-12-02 |
2023-08-12 |
Not clear |
| Pornswan Wasant, Chaiyan Rajchagoo. Down syndrome parents' support group in Thailand Siriraj Hospital, fifteen years experience: a review. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 92. issue 9. 2009-12-01. PMID:19772188. |
it consists of a group of pediatricians, nurses, parents of children with down syndrome (ds) who received care at the genetics clinic, division of medical genetics, department of pediatrics, faculty of medicine siriraj hospital. |
2009-12-01 |
2023-08-12 |
human |
| Michael J Eckrich, Jennifer Domm, Richard Ho, James A Whitlock, Haydar Frangou. Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma. Pediatric blood & cancer. vol 53. issue 7. 2009-11-17. PMID:19760777. |
children with down syndrome (ds) are at increased risk for the development of acute leukemia but they rarely develop other hematologic malignancies or solid tumors. |
2009-11-17 |
2023-08-12 |
Not clear |
| J M Biselli, F B Machado, B L Zampieri, A F Alves da Silva, E M Goloni-Bertollo, R Haddad, M N Eberlin, H Vannucchi, V M Carvalho, E Medina-Acosta, E C Pavarino-Bertell. Double aneuploidy (48,XXY,+21) of maternal origin in a child born to a 13-year-old mother: evaluation of the maternal folate metabolism. Genetic counseling (Geneva, Switzerland). vol 20. issue 3. 2009-11-16. PMID:19852428. |
the infant was born to a 13-year-old mother and presented with the typical clinical features of down syndrome (ds). |
2009-11-16 |
2023-08-12 |
Not clear |
| Ana C Xavier, Yubin Ge, Jeffrey W Tau. Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathology. The Journal of molecular diagnostics : JMD. vol 11. issue 5. 2009-11-03. PMID:19710397. |
the patterns of malignancies in down syndrome (ds) are unique and highlight the relationship between chromosome 21 and cancer. |
2009-11-03 |
2023-08-12 |
Not clear |
| b' Fabio Copped\\xc3\\xa. The complex relationship between folate/homocysteine metabolism and risk of Down syndrome. Mutation research. vol 682. issue 1. 2009-10-29. PMID:19524060.' |
in 1999 it was first reported that impairments in folate/homocysteine metabolism, due to genetic polymorphisms of metabolic enzymes, could increase the risk for having an infant with down syndrome (ds). |
2009-10-29 |
2023-08-12 |
Not clear |
| Ija Talja, Tiia Reimand, Oivi Uibo, Koit Reimand, Silver Aun, Tiina Talvik, Paul A Janmey, Raivo Uib. Antibodies to neurofilaments. Annals of the New York Academy of Sciences. vol 1173. 2009-10-29. PMID:19758141. |
this study determines the occurrence of autoantibodies to the three neurofilament subunits in phosphorylated and dephosphorylated forms and relates these measures to age, human leukocyte antigen (hla), and severity of disease in down syndrome (ds). |
2009-10-29 |
2023-08-12 |
human |
| Diane C Cabelof, Hiral V Patel, Qing Chen, Holly van Remmen, Larry H Matherly, Yubin Ge, Jeffrey W Tau. Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome. Blood. vol 114. issue 13. 2009-10-27. PMID:19633202. |
down syndrome (ds) children have a unique genetic susceptibility to develop leukemia, in particular, acute megakaryocytic leukemia (amkl) associated with somatic gata1 mutations. |
2009-10-27 |
2023-08-12 |
Not clear |
| Holly Edwards, Chengzhi Xie, Katherine M LaFiura, Alan A Dombkowski, Steven A Buck, Julie L Boerner, Jeffrey W Taub, Larry H Matherly, Yubin G. RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia. Blood. vol 114. issue 13. 2009-10-27. PMID:19638627. |
the median level of runx1b transcripts in down syndrome (ds) children with acute megakaryocytic leukemia (amkl) were 4.4-fold (p < .001) lower than that in non-ds amkl cases. |
2009-10-27 |
2023-08-12 |
Not clear |
| Lisa J Russell, Melania Capasso, Inga Vater, Takashi Akasaka, Olivier A Bernard, Maria Jose Calasanz, Thiruppavaii Chandrasekaran, Elise Chapiro, Stephan Gesk, Mike Griffiths, David S Guttery, Claudia Haferlach, Lana Harder, Olaf Heidenreich, Julie Irving, Lyndal Kearney, Florence Nguyen-Khac, Lee Machado, Lynne Minto, Aneela Majid, Anthony V Moorman, Heather Morrison, Vikki Rand, Jonathan C Strefford, Claire Schwab, Holger Tönnies, Martin J S Dyer, Reiner Siebert, Christine J Harriso. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood. vol 114. issue 13. 2009-10-27. PMID:19641190. |
in down syndrome (ds) all and 2 non-ds bcp-all cell lines, crlf2 deregulation was associated with mutations of the jak2 pseudokinase domain, suggesting oncogenic cooperation as well as highlighting a link between non-ds all and jak2 mutations. |
2009-10-27 |
2023-08-12 |
Not clear |
| Juan C Kupferman, Charlotte M Druschel, Gabriel S Kupchi. Increased prevalence of renal and urinary tract anomalies in children with Down syndrome. Pediatrics. vol 124. issue 4. 2009-10-23. PMID:19752083. |
the goal was to investigate the prevalence of renal and urinary tract anomalies (rutas) in a down syndrome (ds) population. |
2009-10-23 |
2023-08-12 |
Not clear |
| Brian G Skotko, George T Capone, Priya S Kishnan. Postnatal diagnosis of Down syndrome: synthesis of the evidence on how best to deliver the news. Pediatrics. vol 124. issue 4. 2009-10-23. PMID:19786436. |
many parents of children with down syndrome (ds) have expressed dissatisfaction with how they learned about their child's diagnosis. |
2009-10-23 |
2023-08-12 |
Not clear |
| Joongkyu Park, Woo-Joo Song, Kwang Chul Chun. Function and regulation of Dyrk1A: towards understanding Down syndrome. Cellular and molecular life sciences : CMLS. vol 66. issue 20. 2009-10-22. PMID:19685005. |
down syndrome (ds) is associated with a variety of symptoms, such as incapacitating mental retardation and neurodegeneration (i.e., alzheimer's disease), that prevent patients from leading fully independent lives. |
2009-10-22 |
2023-08-12 |
Not clear |
| Loyse Hippolyte, Katia Iglesias, Koviljka Barisniko. A new emotional stroop-like task: application to the Down syndrome population. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 24. issue 3. 2009-10-21. PMID:19587065. |
the present study proposed to test the applicability of a new emotional stroop-like paradigm among 49 adults with down syndrome (ds), matched with typically developing children on gender and receptive vocabulary. |
2009-10-21 |
2023-08-12 |
human |
| Alberto Goday-Arno, Mariaina Cerda-Esteva, Juana Antonia Flores-Le-Roux, Juan José Chillaron-Jordan, Josep Maria Corretger, Juan Francisco Cano-Pére. Hyperthyroidism in a population with Down syndrome (DS). Clinical endocrinology. vol 71. issue 1. 2009-10-13. PMID:18793345. |
hyperthyroidism in a population with down syndrome (ds). |
2009-10-13 |
2023-08-12 |
Not clear |