| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Polina Stepensky, Rebecca Brooks, Elisha Waldman, Shoshana Revel-Vilk, Shai Izraeli, Igor Resnick, Michael Weintrau. A rare case of GATA1 negative chemoresistant acute megakaryocytic leukemia in an 8-month-old infant with trisomy 21. Pediatric blood & cancer. vol 54. issue 7. 2010-05-20. PMID:20108342. |
children with down syndrome (ds) have a unique form of acute megakaryocytic leukemia (amkl) characterized by the presence of mutations in the gata1 gene leading to increased chemosensitivity and a favorable outcome. |
2010-05-20 |
2023-08-12 |
Not clear |
| Giada Dogliotti, Emanuela Galliera, Federico Licastro, Massimiliano M Cors. Age-related changes in plasma levels of BDNF in Down syndrome patients. Immunity & ageing : I & A. vol 7. 2010-05-20. PMID:20181009. |
the prevalence of coronary artery diseases is low among down syndrome (ds) patients and they rarely die of atherosclerotic complications. |
2010-05-20 |
2023-08-12 |
Not clear |
| Giada Dogliotti, Emanuela Galliera, Federico Licastro, Massimiliano M Cors. Age-related changes in plasma levels of BDNF in Down syndrome patients. Immunity & ageing : I & A. vol 7. 2010-05-20. PMID:20181009. |
histopathological investigations showed no increase in atherosclerosis, or even a total lack of atherosclerotic changes, in ds aim: the aim of our study is to investigate the relationship between age and brain-derived neurotrophic factor (bdnf) levels in down syndrome (ds). |
2010-05-20 |
2023-08-12 |
Not clear |
| Julie Tandonnet, Jacqueline Clavel, André Baruchel, Fabienne Nacka, Yves Pére. Myeloid leukaemia in children with Down syndrome: report of the registry-based French experience between 1990 and 2003. Pediatric blood & cancer. vol 54. issue 7. 2010-05-20. PMID:20405513. |
to determine the epidemiology of myeloid leukaemia (ml) in children with down syndrome (ds) and the efficacy of two approaches, low-dose cytarabine-based regimen (ldc) and standard-dose intensive chemotherapy (sd). |
2010-05-20 |
2023-08-12 |
Not clear |
| Odessa Yabut, Jason Domogauer, Gabriella D'Arcangel. Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 11. 2010-05-18. PMID:20237271. |
the human dyrk1a gene is located on trisomic chromosome 21 in down syndrome (ds) patients, leading to its overexpression. |
2010-05-18 |
2023-08-12 |
mouse |
| B Tuysuz, A Yavuz, M Ozdil, J Caferler, H Ozo. Atypical Down syndrome phenotype in a girl with 21;21 translocation trisomy. Genetic counseling (Geneva, Switzerland). vol 21. issue 1. 2010-05-14. PMID:20420031. |
fish analyses by ls121 probe for the critical (21q22.2-22.3) region of down syndrome (ds) on interphase blood cells resulted with 30% two signals and 70% three signals, skin fibroblasts showed 84% single signal, 9% two signals and 7% three signals. |
2010-05-14 |
2023-08-12 |
Not clear |
| Christopher J Lemons, Douglas Fuch. Phonological awareness of children with Down syndrome: its role in learning to read and the effectiveness of related interventions. Research in developmental disabilities. vol 31. issue 2. 2010-05-07. PMID:19945821. |
some have suggested that this is not true for children with down syndrome (ds). |
2010-05-07 |
2023-08-12 |
Not clear |
| Teresa Iacono, Jennifer Torr, Hui Yi Won. Relationships amongst age, language and related skills in adults with Down syndrome. Research in developmental disabilities. vol 31. issue 2. 2010-05-07. PMID:20045630. |
studies into the effects of ageing on language in adults with down syndrome (ds) have tended to rely on measures that lack sensitivity to change because they fail to explore across linguistic domains or rely on proxy reports. |
2010-05-07 |
2023-08-12 |
human |
| Meghann Lloyd, Amy Burghardt, Dale A Ulrich, Rosa Angulo-Barros. Physical activity and walking onset in infants with Down syndrome. Adapted physical activity quarterly : APAQ. vol 27. issue 1. 2010-05-06. PMID:20147766. |
infants with down syndrome (ds) are described as being less active and they also experience significant delays in motor development. |
2010-05-06 |
2023-08-12 |
Not clear |
| A C Oliveira, I A Pordeus, C L Luz, S M Paiv. Mothers' perceptions concerning oral health of children and adolescents with Down syndrome: a qualitative approach. European journal of paediatric dentistry. vol 11. issue 1. 2010-05-04. PMID:20359278. |
the aim of this qualitative study was to investigate the perceptions of a group of mothers of children and adolescents with down syndrome (ds) concerning the overall health and oral health of their children. |
2010-05-04 |
2023-08-12 |
Not clear |
| Beatrijs L P Bloemers, Grada M van Bleek, Jan L L Kimpen, Louis Bon. Distinct abnormalities in the innate immune system of children with Down syndrome. The Journal of pediatrics. vol 156. issue 5. 2010-05-03. PMID:20172534. |
to analyze the frequency and phenotype of cells of the innate immune system in the peripheral blood of children with down syndrome (ds). |
2010-05-03 |
2023-08-12 |
Not clear |
| Patrick M Cowley, Lori L Ploutz-Snyder, Tracy Baynard, Kevin Heffernan, Sae Young Jae, Sharon Hsu, Miyoung Lee, Kenneth H Pitetti, Michael P Reiman, Bo Fernhal. Physical fitness predicts functional tasks in individuals with Down syndrome. Medicine and science in sports and exercise. vol 42. issue 2. 2010-04-29. PMID:19927019. |
individuals with down syndrome (ds) exhibit reduced strength and aerobic capacity, which may limit their ability to perform functional tasks of daily living. |
2010-04-29 |
2023-08-12 |
Not clear |
| Kate A Alford, Amy Slender, Lesley Vanes, Zhe Li, Elizabeth M C Fisher, Dean Nizetic, Stuart H Orkin, Irene Roberts, Victor L J Tybulewic. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. Blood. vol 115. issue 14. 2010-04-27. PMID:20154221. |
trisomy of human chromosome 21 (hsa21) results in down syndrome (ds), a disorder that affects many aspects of physiology, including hematopoiesis. |
2010-04-27 |
2023-08-12 |
mouse |
| P S Hans, R England, S Prowse, E Young, P Z Sheeha. UK and Ireland experience of cochlear implants in children with Down syndrome. International journal of pediatric otorhinolaryngology. vol 74. issue 3. 2010-04-26. PMID:20036016. |
down syndrome (ds) is associated with a high incidence of hearing loss. |
2010-04-26 |
2023-08-12 |
Not clear |
| Mona M Shete, Rose Mary S Stocks, Merry E Sebelik, Robert A Schoumache. Effects of adeno-tonsillectomy on polysomnography patterns in Down syndrome children with obstructive sleep apnea: a comparative study with children without Down syndrome. International journal of pediatric otorhinolaryngology. vol 74. issue 3. 2010-04-26. PMID:20097432. |
to determine if adeno-tonsillectomy (t&a) in children with down syndrome (ds) improves breathing, measured by apnea hypopnea index (ahi), rapid eye movement ahi (rem-ahi) and the lowest oxygen desaturation (sao2), and sleep disruption, measured by arousal index (ari) and time spent in stages 1-4 and rapid eye movement (rem) sleep and compare these results with a group of non-ds children with obstructive sleep apnea (osa). |
2010-04-26 |
2023-08-12 |
Not clear |
| Babu Rao Vundinti, Seema Korgaonkar, Kanjaksha Ghos. Familial small supernumerary marker chromosome (sSMC) (14)(:p11-q11:) [corrected] in a child with translocation Down syndrome. Indian journal of pediatrics. vol 76. issue 12. 2010-04-21. PMID:20012787. |
we report a case of familial small supernumerary marker chromosome (ssmc)in a child with translocation down syndrome (ds)and mother. |
2010-04-21 |
2023-08-12 |
Not clear |
| Beth A Smith, Nick Stergiou, Beverly D Ulric. Lyapunov exponent and surrogation analysis of patterns of variability: profiles in new walkers with and without down syndrome. Motor control. vol 14. issue 1. 2010-04-15. PMID:20237407. |
in previous studies we found that preadolescents with down syndrome (ds) produce higher amounts of variability (smith et al., 2007) and larger lyapunov exponent (lye) values (indicating more instability) during walking than their peers with typical development (td) (buzzi & ulrich, 2004). |
2010-04-15 |
2023-08-12 |
Not clear |
| Adriana S Lima, Bárbara R Cardoso, Silvia F Cozzolin. Nutritional status of zinc in children with Down syndrome. Biological trace element research. vol 133. issue 1. 2010-04-08. PMID:19468695. |
experimental and clinical studies have established that zinc metabolism is altered in individuals with down syndrome (ds). |
2010-04-08 |
2023-08-12 |
Not clear |
| Katheleen J Gardine. Molecular basis of pharmacotherapies for cognition in Down syndrome. Trends in pharmacological sciences. vol 31. issue 2. 2010-04-07. PMID:19963286. |
intellectual disability in down syndrome (ds) ranges from low normal to severely impaired and has a significant impact on the quality-of-life of the individuals affected and their families. |
2010-04-07 |
2023-08-12 |
mouse |
| Christian Arriagada, Miguel Bustamante, Illani Atwater, Eduardo Rojas, Raúl Caviedes, Pablo Caviede. Apoptosis is directly related to intracellular amyloid accumulation in a cell line derived from the cerebral cortex of a trisomy 16 mouse, an animal model of Down syndrome. Neuroscience letters. vol 470. issue 1. 2010-04-06. PMID:20043975. |
human down syndrome (ds) represents the most frequent cause of mental retardation associated to a genetic condition. |
2010-04-06 |
2023-08-12 |
mouse |