| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Tsao, C Kindelberge. Variability of cognitive development in children with Down syndrome: relevance of good reasons for using the cluster procedure. Research in developmental disabilities. vol 30. issue 3. 2009-05-20. PMID:19036558. |
the main goal of this cross-sectional study was to demonstrate that, in addition to a main change during childhood, the cognitive development of children with down syndrome (ds) is characterized by interindividual variability in their cognitive functioning. |
2009-05-20 |
2023-08-12 |
Not clear |
| Joy Vink, Maddelena Incerti, Laura Toso, Robin Roberson, Daniel Abebe, Catherine Y Spon. Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors. American journal of obstetrics and gynecology. vol 200. issue 5. 2009-05-18. PMID:19327737. |
down syndrome (ds) affects 1/800 infants. |
2009-05-18 |
2023-08-12 |
mouse |
| Robert Lyle, Frédérique Béna, Sarantis Gagos, Corinne Gehrig, Gipsy Lopez, Albert Schinzel, James Lespinasse, Armand Bottani, Sophie Dahoun, Laurence Taine, Martine Doco-Fenzy, Pascale Cornillet-Lefèbvre, Anna Pelet, Stanislas Lyonnet, Annick Toutain, Laurence Colleaux, Jürgen Horst, Ingo Kennerknecht, Nobuaki Wakamatsu, Maria Descartes, Judy C Franklin, Lina Florentin-Arar, Sophia Kitsiou, Emilie Aït Yahya-Graison, Maher Costantine, Pierre-Marie Sinet, Jean M Delabar, Stylianos E Antonaraki. Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21. European journal of human genetics : EJHG. vol 17. issue 4. 2009-05-08. PMID:19002211. |
down syndrome (ds) is one of the most frequent congenital birth defects, and the most common genetic cause of mental retardation. |
2009-05-08 |
2023-08-12 |
Not clear |
| Monika J Stankiewicz, John D Crispin. ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells. Blood. vol 113. issue 14. 2009-05-08. PMID:19168790. |
people with down syndrome (ds), who are trisomic for hsa21, are predisposed to acute megakaryoblastic leukemia (amkl). |
2009-05-08 |
2023-08-12 |
human |
| Taís de S Lopes, Daniele M Ferreira, Rosangela A Pereira, Gloria V da Veiga, Vania M R de Marin. Assessment of anthropometric indexes of children and adolescents with Down syndrome. Jornal de pediatria. vol 84. issue 4. 2009-05-05. PMID:18688549. |
to compare the agreement in the classification of the weight-for-age (w/a) and height-for-age (ha) indexes for children and adolescents with down syndrome (ds) according to selected international reference distributions. |
2009-05-05 |
2023-08-12 |
Not clear |
| Andrea Contestabile, Tatiana Fila, Renata Bartesaghi, Elisabetta Cian. Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome. Brain pathology (Zurich, Switzerland). vol 19. issue 2. 2009-05-01. PMID:18482164. |
mental retardation, the hallmark of down syndrome (ds), has been attributed to the reduced number of neurons populating the ds brain. |
2009-05-01 |
2023-08-12 |
mouse |
| Sébastien Malinge, Shai Izraeli, John D Crispin. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood. vol 113. issue 12. 2009-04-28. PMID:19139078. |
children with down syndrome (ds) show a spectrum of clinical anomalies, including cognitive impairment, cardiac malformations, and craniofacial dysmorphy. |
2009-04-28 |
2023-08-12 |
Not clear |
| Eliza Porto-Cunha, Suelly Cecilia Olivan Limong. Communicative profile used by children with Down syndrome. Pro-fono : revista de atualizacao cientifica. vol 20. issue 4. 2009-04-23. PMID:19142467. |
the communication of children with down syndrome (ds) is frequently impaired due to difficulties in the phonological, syntactic and semantic aspects of language. |
2009-04-23 |
2023-08-12 |
Not clear |
| S B Freeman, C P Torfs, P A Romitti, M H Royle, C Druschel, C A Hobbs, S L Sherma. Congenital gastrointestinal defects in Down syndrome: a report from the Atlanta and National Down Syndrome Projects. Clinical genetics. vol 75. issue 2. 2009-04-16. PMID:19021635. |
we report down syndrome (ds)-associated congenital gastrointestinal (gi) defects identified during a 15 year, population-based study of the etiology and phenotypic consequences of trisomy 21. |
2009-04-16 |
2023-08-12 |
Not clear |
| Fabio Coppedè, Francesca Migheli, Stefania Bargagna, Gabriele Siciliano, Ivana Antonucci, Liborio Stuppia, Giandomenico Palka, Lucia Miglior. Association of maternal polymorphisms in folate metabolizing genes with chromosome damage and risk of Down syndrome offspring. Neuroscience letters. vol 449. issue 1. 2009-04-15. PMID:18983896. |
we analyzed the role of six common polymorphisms in folate metabolizing genes as possible risk factors for having a child with down syndrome (ds) in 94 italian mothers of a ds child (mds) and 113 matched control mothers, both aged less than 35 years at conception. |
2009-04-15 |
2023-08-12 |
Not clear |
| Jason Lockrow, Annamalai Prakasam, Peng Huang, Heather Bimonte-Nelson, Kumar Sambamurti, Ann-Charlotte Granhol. Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model. Experimental neurology. vol 216. issue 2. 2009-04-15. PMID:19135442. |
down syndrome (ds) individuals develop several neuropathological hallmarks seen in alzheimer's disease, including cognitive decline and the early loss of cholinergic markers in the basal forebrain. |
2009-04-15 |
2023-08-12 |
mouse |
| J H Sitz, K Baumgärtel, B Hämmerle, C Papadopoulos, P Hekerman, F J Tejedor, W Becker, B Lut. The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4. Neuroscience. vol 157. issue 3. 2009-04-14. PMID:18938227. |
dyrk1a is overexpressed in down syndrome (ds) and has recently been implicated in several neurodegenerative diseases. |
2009-04-14 |
2023-08-12 |
mouse |
| Frances K Wiseman, Kate A Alford, Victor L J Tybulewicz, Elizabeth M C Fishe. Down syndrome--recent progress and future prospects. Human molecular genetics. vol 18. issue R1. 2009-04-14. PMID:19297404. |
down syndrome (ds) is caused by trisomy of chromosome 21 (hsa21) and is associated with a number of deleterious phenotypes, including learning disability, heart defects, early-onset alzheimer's disease and childhood leukaemia. |
2009-04-14 |
2023-08-12 |
mouse |
| Joachim Höger, David Patterson, Harald Höger, Ki-Shuk Shim, Hermann Bubna-Littitz, Gert Lube. Mice transgenic for reduced folate carrier: an animal model of Down syndrome? Amino acids. vol 36. issue 2. 2009-04-10. PMID:18414976. |
in a previous publication we observed aberrant levels of the human reduced folate carrier (hrfc) in cortex from fetal down syndrome (ds) subjects. |
2009-04-10 |
2023-08-12 |
mouse |
| Randall J Roper, Justin F VanHorn, Colyn C Cain, Roger H Reeve. A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog. Mechanisms of development. vol 126. issue 3-4. 2009-04-10. PMID:19056491. |
trisomy 21 results in phenotypes collectively referred to as down syndrome (ds) including characteristic facial dysmorphology. |
2009-04-10 |
2023-08-12 |
mouse |
| Catherine L Carmichael, Ian J Majewski, Warren S Alexander, Donald Metcalf, Douglas J Hilton, Chelsee A Hewitt, Hamish S Scot. Hematopoietic defects in the Ts1Cje mouse model of Down syndrome. Blood. vol 113. issue 9. 2009-04-10. PMID:19109561. |
down syndrome (ds) persons are born with various hematopoietic abnormalities, ranging from relatively benign, such as neutrophilia and macrocytosis, to a more severe transient myeloproliferative disorder (tmd). |
2009-04-10 |
2023-08-12 |
mouse |
| A Siddiqui, T Lacroix, M R Stasko, J J Scott-McKean, A C S Costa, K J Gardine. Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801. Genes, brain, and behavior. vol 7. issue 7. 2009-04-10. PMID:19125866. |
down syndrome (ds), caused by trisomy of human chromosome 21 (chr21), is the most common genetic cause of intellectual disability. |
2009-04-10 |
2023-08-12 |
mouse |
| S Basu, V Pooniya, A Kumar, B K Da. Down syndrome with cerebral arteriovenous malformation. Annals of tropical paediatrics. vol 29. issue 1. 2009-04-07. PMID:19222937. |
down syndrome (ds) or trisomy 21 is one of the most common and best known of all chromosomal disorders. |
2009-04-07 |
2023-08-12 |
Not clear |
| Simona Ognjanovic, Susan Puumala, Logan G Spector, Franklin O Smith, Leslie L Robison, Andrew F Olshan, Julie A Ros. Maternal health conditions during pregnancy and acute leukemia in children with Down syndrome: A Children's Oncology Group study. Pediatric blood & cancer. vol 52. issue 5. 2009-04-06. PMID:19148952. |
children with down syndrome (ds) have about a 20-fold increased risk of developing leukemia. |
2009-04-06 |
2023-08-12 |
Not clear |
| Miguel Galeote, Pilar Soto, Elena Checa, Aurora Gómez, Elena Lamel. The acquisition of productive vocabulary in Spanish children with Down syndrome. Journal of intellectual & developmental disability. vol 33. issue 4. 2009-04-01. PMID:19039689. |
it is generally assumed that children with down syndrome (ds) present a deficit in lexical production relative to their cognitive abilities. |
2009-04-01 |
2023-08-12 |
Not clear |