| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pornswan Wasant, Chaiyan Rajchagoo. Down syndrome parents' support group in Thailand Siriraj Hospital, fifteen years experience: a review. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 92. issue 9. 2009-12-01. PMID:19772188. |
it consists of a group of pediatricians, nurses, parents of children with down syndrome (ds) who received care at the genetics clinic, division of medical genetics, department of pediatrics, faculty of medicine siriraj hospital. |
2009-12-01 |
2023-08-12 |
human |
| Michael J Eckrich, Jennifer Domm, Richard Ho, James A Whitlock, Haydar Frangou. Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma. Pediatric blood & cancer. vol 53. issue 7. 2009-11-17. PMID:19760777. |
children with down syndrome (ds) are at increased risk for the development of acute leukemia but they rarely develop other hematologic malignancies or solid tumors. |
2009-11-17 |
2023-08-12 |
Not clear |
| J M Biselli, F B Machado, B L Zampieri, A F Alves da Silva, E M Goloni-Bertollo, R Haddad, M N Eberlin, H Vannucchi, V M Carvalho, E Medina-Acosta, E C Pavarino-Bertell. Double aneuploidy (48,XXY,+21) of maternal origin in a child born to a 13-year-old mother: evaluation of the maternal folate metabolism. Genetic counseling (Geneva, Switzerland). vol 20. issue 3. 2009-11-16. PMID:19852428. |
the infant was born to a 13-year-old mother and presented with the typical clinical features of down syndrome (ds). |
2009-11-16 |
2023-08-12 |
Not clear |
| Ana C Xavier, Yubin Ge, Jeffrey W Tau. Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathology. The Journal of molecular diagnostics : JMD. vol 11. issue 5. 2009-11-03. PMID:19710397. |
the patterns of malignancies in down syndrome (ds) are unique and highlight the relationship between chromosome 21 and cancer. |
2009-11-03 |
2023-08-12 |
Not clear |
| b' Fabio Copped\\xc3\\xa. The complex relationship between folate/homocysteine metabolism and risk of Down syndrome. Mutation research. vol 682. issue 1. 2009-10-29. PMID:19524060.' |
in 1999 it was first reported that impairments in folate/homocysteine metabolism, due to genetic polymorphisms of metabolic enzymes, could increase the risk for having an infant with down syndrome (ds). |
2009-10-29 |
2023-08-12 |
Not clear |
| Ija Talja, Tiia Reimand, Oivi Uibo, Koit Reimand, Silver Aun, Tiina Talvik, Paul A Janmey, Raivo Uib. Antibodies to neurofilaments. Annals of the New York Academy of Sciences. vol 1173. 2009-10-29. PMID:19758141. |
this study determines the occurrence of autoantibodies to the three neurofilament subunits in phosphorylated and dephosphorylated forms and relates these measures to age, human leukocyte antigen (hla), and severity of disease in down syndrome (ds). |
2009-10-29 |
2023-08-12 |
human |
| Diane C Cabelof, Hiral V Patel, Qing Chen, Holly van Remmen, Larry H Matherly, Yubin Ge, Jeffrey W Tau. Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome. Blood. vol 114. issue 13. 2009-10-27. PMID:19633202. |
down syndrome (ds) children have a unique genetic susceptibility to develop leukemia, in particular, acute megakaryocytic leukemia (amkl) associated with somatic gata1 mutations. |
2009-10-27 |
2023-08-12 |
Not clear |
| Holly Edwards, Chengzhi Xie, Katherine M LaFiura, Alan A Dombkowski, Steven A Buck, Julie L Boerner, Jeffrey W Taub, Larry H Matherly, Yubin G. RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia. Blood. vol 114. issue 13. 2009-10-27. PMID:19638627. |
the median level of runx1b transcripts in down syndrome (ds) children with acute megakaryocytic leukemia (amkl) were 4.4-fold (p < .001) lower than that in non-ds amkl cases. |
2009-10-27 |
2023-08-12 |
Not clear |
| Lisa J Russell, Melania Capasso, Inga Vater, Takashi Akasaka, Olivier A Bernard, Maria Jose Calasanz, Thiruppavaii Chandrasekaran, Elise Chapiro, Stephan Gesk, Mike Griffiths, David S Guttery, Claudia Haferlach, Lana Harder, Olaf Heidenreich, Julie Irving, Lyndal Kearney, Florence Nguyen-Khac, Lee Machado, Lynne Minto, Aneela Majid, Anthony V Moorman, Heather Morrison, Vikki Rand, Jonathan C Strefford, Claire Schwab, Holger Tönnies, Martin J S Dyer, Reiner Siebert, Christine J Harriso. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood. vol 114. issue 13. 2009-10-27. PMID:19641190. |
in down syndrome (ds) all and 2 non-ds bcp-all cell lines, crlf2 deregulation was associated with mutations of the jak2 pseudokinase domain, suggesting oncogenic cooperation as well as highlighting a link between non-ds all and jak2 mutations. |
2009-10-27 |
2023-08-12 |
Not clear |
| Juan C Kupferman, Charlotte M Druschel, Gabriel S Kupchi. Increased prevalence of renal and urinary tract anomalies in children with Down syndrome. Pediatrics. vol 124. issue 4. 2009-10-23. PMID:19752083. |
the goal was to investigate the prevalence of renal and urinary tract anomalies (rutas) in a down syndrome (ds) population. |
2009-10-23 |
2023-08-12 |
Not clear |
| Brian G Skotko, George T Capone, Priya S Kishnan. Postnatal diagnosis of Down syndrome: synthesis of the evidence on how best to deliver the news. Pediatrics. vol 124. issue 4. 2009-10-23. PMID:19786436. |
many parents of children with down syndrome (ds) have expressed dissatisfaction with how they learned about their child's diagnosis. |
2009-10-23 |
2023-08-12 |
Not clear |
| Joongkyu Park, Woo-Joo Song, Kwang Chul Chun. Function and regulation of Dyrk1A: towards understanding Down syndrome. Cellular and molecular life sciences : CMLS. vol 66. issue 20. 2009-10-22. PMID:19685005. |
down syndrome (ds) is associated with a variety of symptoms, such as incapacitating mental retardation and neurodegeneration (i.e., alzheimer's disease), that prevent patients from leading fully independent lives. |
2009-10-22 |
2023-08-12 |
Not clear |
| Loyse Hippolyte, Katia Iglesias, Koviljka Barisniko. A new emotional stroop-like task: application to the Down syndrome population. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 24. issue 3. 2009-10-21. PMID:19587065. |
the present study proposed to test the applicability of a new emotional stroop-like paradigm among 49 adults with down syndrome (ds), matched with typically developing children on gender and receptive vocabulary. |
2009-10-21 |
2023-08-12 |
human |
| Alberto Goday-Arno, Mariaina Cerda-Esteva, Juana Antonia Flores-Le-Roux, Juan José Chillaron-Jordan, Josep Maria Corretger, Juan Francisco Cano-Pére. Hyperthyroidism in a population with Down syndrome (DS). Clinical endocrinology. vol 71. issue 1. 2009-10-13. PMID:18793345. |
hyperthyroidism in a population with down syndrome (ds). |
2009-10-13 |
2023-08-12 |
Not clear |
| Alberto Goday-Arno, Mariaina Cerda-Esteva, Juana Antonia Flores-Le-Roux, Juan José Chillaron-Jordan, Josep Maria Corretger, Juan Francisco Cano-Pére. Hyperthyroidism in a population with Down syndrome (DS). Clinical endocrinology. vol 71. issue 1. 2009-10-13. PMID:18793345. |
thyroid disorders are frequent in patients with down syndrome (ds). |
2009-10-13 |
2023-08-12 |
Not clear |
| Martin Benesch, Andrea Moser, Petra Sovinz, Herwig Lackner, Wolfgang Schwinger, Hans Eder, Christian Urba. Medulloblastoma in a child with down syndrome: long-term remission with multimodality treatment. Pediatric blood & cancer. vol 53. issue 6. 2009-10-13. PMID:19489060. |
a 4(3/4)-year-old male with down syndrome (ds) presented with unsteady gait and fatigue. |
2009-10-13 |
2023-08-12 |
Not clear |
| Yuanxin Chen, Victor V Dyakin, Craig A Branch, Babak Ardekani, Dunsheng Yang, David N Guilfoyle, Jesse Peterson, Corrinne Peterhoff, Stephen D Ginsberg, Anne M Cataldo, Ralph A Nixo. In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model. Neurobiology of aging. vol 30. issue 9. 2009-10-09. PMID:18180075. |
in vivo quantitative magnetic resonance imaging (mri) was employed to detect brain pathology and map its distribution within control, disomic mice (2n) and in ts65dn and ts1cje trisomy mice with features of human down syndrome (ds). |
2009-10-09 |
2023-08-12 |
mouse |
| Floyd Sarsoza, Tommy Saing, Rakez Kayed, Robert Dahlin, Malcolm Dick, Camille Broadwater-Hollifield, Scott Mobley, Ira Lott, Eric Doran, Daniel Gillen, Clifford Anderson-Bergman, David H Cribbs, Charles Glabe, Elizabeth Hea. A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain. Acta neuropathologica. vol 118. issue 4. 2009-10-08. PMID:19360426. |
beta-amyloid (abeta) is thought to be a key contributor to the pathogenesis of alzheimer disease (ad) in the general population and in adults with down syndrome (ds). |
2009-10-08 |
2023-08-12 |
mouse |
| Harold L Kleinert, Carol A Lunney, Lynn Campbell, James E Ferguso. Improving residents' understanding of issues, comfort levels, and patient needs regarding screening for and diagnosing Down syndrome. American journal of obstetrics and gynecology. vol 201. issue 3. 2009-10-08. PMID:19631921. |
this study assessed obstetrics and gynecology and pediatrics residents' knowledge about down syndrome (ds) and their comfort in delivering a prenatal or postnatal diagnosis of ds before and after interaction with a web-based tutorial. |
2009-10-08 |
2023-08-12 |
Not clear |
| Julie-Anne Little, J Margaret Woodhouse, Kathryn J Saunder. Corneal power and astigmatism in Down syndrome. Optometry and vision science : official publication of the American Academy of Optometry. vol 86. issue 6. 2009-10-06. PMID:19390470. |
corneal and crystalline lens shape differ in down syndrome (ds) compared with developmentally normal populations. |
2009-10-06 |
2023-08-12 |
Not clear |