| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Myriam Guerra, Maria Gine-Garriga, Bo Fernhal. Reliability of Wingate testing in adolescents with Down syndrome. Pediatric exercise science. vol 21. issue 1. 2009-06-09. PMID:19411710. |
the wingate anaerobic test (want) has not been used to assess individuals with down syndrome (ds) and it is unknown if it is reliable in this population. |
2009-06-09 |
2023-08-12 |
human |
| Joongkyu Park, Yohan Oh, Kwang Chul Chun. Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1. BMB reports. vol 42. issue 1. 2009-06-08. PMID:19192387. |
the most common genetic disorder down syndrome (ds) displays various developmental defects including mental retardation, learning and memory deficit, the early onset of alzheimer's disease (ad), congenital heart disease, and craniofacial abnormalities. |
2009-06-08 |
2023-08-12 |
human |
| Josefine Palle, Palle Josefine, Britt-Marie Frost, Frost Britt-Marie, Curt Petersson, Petersson Curt, Henrik Hasle, Hasle Henrik, Marit Hellebostad, Hellebostad Marit, Jukka Kanerva, Kanerva Jukka, Kjeld Schmiegelow, Schmiegelow Kjeld, Gudmar Lönnerholm, Lönnerholm Gudma. Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia. Anti-cancer drugs. vol 20. issue 1. 2009-06-04. PMID:19342996. |
we studied the pharmacokinetics of 6-thioguanine (6tg) in 50 children treated for newly diagnosed acute myeloid leukemia, four of them with down syndrome (ds). |
2009-06-04 |
2023-08-12 |
Not clear |
| Kevin S Heffernan, Jacob J Sosnoff, Edward Ofori, Sae Young Jae, Tracy Baynard, Scott R Collier, Stella Goulopoulou, Arturo Figueroa, Jeffrey A Woods, Kenneth H Pitetti, Bo Fernhal. Complexity of force output during static exercise in individuals with Down syndrome. Journal of applied physiology (Bethesda, Md. : 1985). vol 106. issue 4. 2009-05-29. PMID:19164775. |
force variability is greater in individuals with down syndrome (ds) compared with persons without ds and is similar to that seen with normal aging. |
2009-05-29 |
2023-08-12 |
Not clear |
| Krithika Nandakumar, Susan J Lea. Bifocals in Down Syndrome Study (BiDS): design and baseline visual function. Optometry and vision science : official publication of the American Academy of Optometry. vol 86. issue 3. 2009-05-28. PMID:19182702. |
among children and young people with down syndrome (ds) there is a high prevalence of reduced accommodation. |
2009-05-28 |
2023-08-12 |
Not clear |
| Nadia P Belichenko, Pavel V Belichenko, Alexander M Kleschevnikov, Ahmad Salehi, Roger H Reeves, William C Moble. The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 18. 2009-05-28. PMID:19420260. |
down syndrome (ds) can be modeled in mice segmentally trisomic for mouse chromosome 16. |
2009-05-28 |
2023-08-12 |
mouse |
| Amos Gaikwad, Cassia L Rye, Meenakshi Devidas, Nyla A Heerema, Andrew J Carroll, Shai Izraeli, Sharon E Plon, Giuseppe Basso, Andrea Pession, Karen R Rabi. Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukaemia. British journal of haematology. vol 144. issue 6. 2009-05-26. PMID:19120350. |
recurrent, prognostically significant chromosomal abnormalities occur in approximately 75% of paediatric acute lymphoblastic leukaemia (all), but only infrequently in children with down syndrome (ds) and all. |
2009-05-26 |
2023-08-12 |
Not clear |
| V P Prasher, S G Sajith, S D Rees, A Patel, S Tewari, N Schupf, W B Zigma. Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down syndrome. International journal of geriatric psychiatry. vol 23. issue 11. 2009-05-21. PMID:18464295. |
virtually all adults with down syndrome (ds) have neuropathological manifestations of dementia in alzheimer's disease (dad) but not all develop clinical psychopathology. |
2009-05-21 |
2023-08-12 |
Not clear |
| John Van Borsel, An Vandermeule. Cluttering in Down syndrome. Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP). vol 60. issue 6. 2009-05-20. PMID:19011303. |
to study the occurrence of cluttering in individuals with down syndrome (ds) taking into account the wide range of symptoms that may be found in cluttering. |
2009-05-20 |
2023-08-12 |
Not clear |
| R Tsao, C Kindelberge. Variability of cognitive development in children with Down syndrome: relevance of good reasons for using the cluster procedure. Research in developmental disabilities. vol 30. issue 3. 2009-05-20. PMID:19036558. |
the main goal of this cross-sectional study was to demonstrate that, in addition to a main change during childhood, the cognitive development of children with down syndrome (ds) is characterized by interindividual variability in their cognitive functioning. |
2009-05-20 |
2023-08-12 |
Not clear |
| Joy Vink, Maddelena Incerti, Laura Toso, Robin Roberson, Daniel Abebe, Catherine Y Spon. Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors. American journal of obstetrics and gynecology. vol 200. issue 5. 2009-05-18. PMID:19327737. |
down syndrome (ds) affects 1/800 infants. |
2009-05-18 |
2023-08-12 |
mouse |
| Robert Lyle, Frédérique Béna, Sarantis Gagos, Corinne Gehrig, Gipsy Lopez, Albert Schinzel, James Lespinasse, Armand Bottani, Sophie Dahoun, Laurence Taine, Martine Doco-Fenzy, Pascale Cornillet-Lefèbvre, Anna Pelet, Stanislas Lyonnet, Annick Toutain, Laurence Colleaux, Jürgen Horst, Ingo Kennerknecht, Nobuaki Wakamatsu, Maria Descartes, Judy C Franklin, Lina Florentin-Arar, Sophia Kitsiou, Emilie Aït Yahya-Graison, Maher Costantine, Pierre-Marie Sinet, Jean M Delabar, Stylianos E Antonaraki. Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21. European journal of human genetics : EJHG. vol 17. issue 4. 2009-05-08. PMID:19002211. |
down syndrome (ds) is one of the most frequent congenital birth defects, and the most common genetic cause of mental retardation. |
2009-05-08 |
2023-08-12 |
Not clear |
| Monika J Stankiewicz, John D Crispin. ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells. Blood. vol 113. issue 14. 2009-05-08. PMID:19168790. |
people with down syndrome (ds), who are trisomic for hsa21, are predisposed to acute megakaryoblastic leukemia (amkl). |
2009-05-08 |
2023-08-12 |
human |
| Taís de S Lopes, Daniele M Ferreira, Rosangela A Pereira, Gloria V da Veiga, Vania M R de Marin. Assessment of anthropometric indexes of children and adolescents with Down syndrome. Jornal de pediatria. vol 84. issue 4. 2009-05-05. PMID:18688549. |
to compare the agreement in the classification of the weight-for-age (w/a) and height-for-age (ha) indexes for children and adolescents with down syndrome (ds) according to selected international reference distributions. |
2009-05-05 |
2023-08-12 |
Not clear |
| Andrea Contestabile, Tatiana Fila, Renata Bartesaghi, Elisabetta Cian. Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome. Brain pathology (Zurich, Switzerland). vol 19. issue 2. 2009-05-01. PMID:18482164. |
mental retardation, the hallmark of down syndrome (ds), has been attributed to the reduced number of neurons populating the ds brain. |
2009-05-01 |
2023-08-12 |
mouse |
| Sébastien Malinge, Shai Izraeli, John D Crispin. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood. vol 113. issue 12. 2009-04-28. PMID:19139078. |
children with down syndrome (ds) show a spectrum of clinical anomalies, including cognitive impairment, cardiac malformations, and craniofacial dysmorphy. |
2009-04-28 |
2023-08-12 |
Not clear |
| Eliza Porto-Cunha, Suelly Cecilia Olivan Limong. Communicative profile used by children with Down syndrome. Pro-fono : revista de atualizacao cientifica. vol 20. issue 4. 2009-04-23. PMID:19142467. |
the communication of children with down syndrome (ds) is frequently impaired due to difficulties in the phonological, syntactic and semantic aspects of language. |
2009-04-23 |
2023-08-12 |
Not clear |
| S B Freeman, C P Torfs, P A Romitti, M H Royle, C Druschel, C A Hobbs, S L Sherma. Congenital gastrointestinal defects in Down syndrome: a report from the Atlanta and National Down Syndrome Projects. Clinical genetics. vol 75. issue 2. 2009-04-16. PMID:19021635. |
we report down syndrome (ds)-associated congenital gastrointestinal (gi) defects identified during a 15 year, population-based study of the etiology and phenotypic consequences of trisomy 21. |
2009-04-16 |
2023-08-12 |
Not clear |
| Fabio Coppedè, Francesca Migheli, Stefania Bargagna, Gabriele Siciliano, Ivana Antonucci, Liborio Stuppia, Giandomenico Palka, Lucia Miglior. Association of maternal polymorphisms in folate metabolizing genes with chromosome damage and risk of Down syndrome offspring. Neuroscience letters. vol 449. issue 1. 2009-04-15. PMID:18983896. |
we analyzed the role of six common polymorphisms in folate metabolizing genes as possible risk factors for having a child with down syndrome (ds) in 94 italian mothers of a ds child (mds) and 113 matched control mothers, both aged less than 35 years at conception. |
2009-04-15 |
2023-08-12 |
Not clear |
| Jason Lockrow, Annamalai Prakasam, Peng Huang, Heather Bimonte-Nelson, Kumar Sambamurti, Ann-Charlotte Granhol. Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model. Experimental neurology. vol 216. issue 2. 2009-04-15. PMID:19135442. |
down syndrome (ds) individuals develop several neuropathological hallmarks seen in alzheimer's disease, including cognitive decline and the early loss of cholinergic markers in the basal forebrain. |
2009-04-15 |
2023-08-12 |
mouse |