| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Urbina, S Pineda, L Piñango, I Carreira, L Lim. [3H]Paroxetine binding to human peripheral lymphocyte membranes of patients with major depression before and after treatment with fluoxetine. International journal of immunopharmacology. vol 21. issue 10. 2003-08-06. PMID:12609459. |
we determined the density of serotonin uptake sites by the binding of [3h]paroxetine to blood peripheral lymphocyte membrane preparations of controls and of patients with major depression before and after treatment with fluoxetine for six weeks. |
2003-08-06 |
2023-08-12 |
human |
| J F W Deaki. Depression and antisocial personality disorder: two contrasting disorders of 5HT function. Journal of neural transmission. Supplementum. issue 64. 2003-08-06. PMID:12830930. |
depression and antisocial personality disorder: two contrasting disorders of 5ht function. |
2003-08-06 |
2023-08-12 |
Not clear |
| J F W Deaki. Depression and antisocial personality disorder: two contrasting disorders of 5HT function. Journal of neural transmission. Supplementum. issue 64. 2003-08-06. PMID:12830930. |
impaired 5ht functioning has been implicated in two very different psychiatric syndromes: antisocial personality disorder and depression. |
2003-08-06 |
2023-08-12 |
Not clear |
| Shamsah Sonawalla, Nabonita Chakraborty, Rajesh Parik. Treatment of major depression and anxiety with the selective serotonin re-uptake enhancer tianeptine in the outpatient psychiatric care setting of India. Journal of the Indian Medical Association. vol 101. issue 2. 2003-08-05. PMID:12841497. |
treatment of major depression and anxiety with the selective serotonin re-uptake enhancer tianeptine in the outpatient psychiatric care setting of india. |
2003-08-05 |
2023-08-12 |
Not clear |
| Shamsah Sonawalla, Nabonita Chakraborty, Rajesh Parik. Treatment of major depression and anxiety with the selective serotonin re-uptake enhancer tianeptine in the outpatient psychiatric care setting of India. Journal of the Indian Medical Association. vol 101. issue 2. 2003-08-05. PMID:12841497. |
in the outpatient psychiatric care setting, patients with major depression and anxiety comply poorly with traditional tricyclic antidepressants and specific serotonin re-uptake inhibitor treatment. |
2003-08-05 |
2023-08-12 |
Not clear |
| Thomas P Guck, Gary N Elsasser, Michael G Kavan, Eugene J Baron. Depression and congestive heart failure. Congestive heart failure (Greenwich, Conn.). vol 9. issue 3. 2003-08-04. PMID:12826775. |
pharmacologically, the selective serotonin reuptake inhibitors are recommended, whereas the tricyclic antidepressants are not recommended for depression in congestive heart failure patients. |
2003-08-04 |
2023-08-12 |
Not clear |
| Corrado Barbui, Mauro Percudani, Matthew Hotop. Economic evaluation of antidepressive agents: a systematic critique of experimental and observational studies. Journal of clinical psychopharmacology. vol 23. issue 2. 2003-08-01. PMID:12640216. |
the purpose of this study was to examine whether experimental and observational pharmacoeconomic analyses of antidepressant drugs support the choice of one of the selective serotonin reuptake inhibitors or newer antidepressants as first-line treatment for patients with major depression. |
2003-08-01 |
2023-08-12 |
Not clear |
| Avshalom Caspi, Karen Sugden, Terrie E Moffitt, Alan Taylor, Ian W Craig, HonaLee Harrington, Joseph McClay, Jonathan Mill, Judy Martin, Antony Braithwaite, Richie Poulto. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (New York, N.Y.). vol 301. issue 5631. 2003-08-01. PMID:12869766. |
a functional polymorphism in the promoter region of the serotonin transporter (5-ht t) gene was found to moderate the influence of stressful life events on depression. |
2003-08-01 |
2023-08-12 |
Not clear |
| Michelle Landry, Thérèse Di Paol. Effect of chronic estradiol, tamoxifen or raloxifene treatment on serotonin 5-HT1A receptor. Brain research. Molecular brain research. vol 112. issue 1-2. 2003-07-31. PMID:12670705. |
the 5-ht(1a) receptor has been suggested to be implicated in depression and anxiety. |
2003-07-31 |
2023-08-12 |
rat |
| Veronika Butterwec. Mechanism of action of St John's wort in depression : what is known? CNS drugs. vol 17. issue 8. 2003-07-28. PMID:12775192. |
in vivo st john's wort extract leads to a downregulation of beta-adrenergic receptors and an upregulation of serotonin 5-ht(2) receptors in the rat frontal cortex and causes changes in neurotransmitter concentrations in brain areas that are implicated in depression. |
2003-07-28 |
2023-08-12 |
rat |
| B Eggers, W Hermann, H Barthel, O Sabri, A Wagner, S Hess. The degree of depression in Hamilton rating scale is correlated with the density of presynaptic serotonin transporters in 23 patients with Wilson's disease. Journal of neurology. vol 250. issue 5. 2003-07-25. PMID:12736737. |
the degree of depression in hamilton rating scale is correlated with the density of presynaptic serotonin transporters in 23 patients with wilson's disease. |
2003-07-25 |
2023-08-12 |
Not clear |
| Stephen M Stah. The ups and downs of novel antiemetic drugs, part 2: an illustration. The Journal of clinical psychiatry. vol 64. issue 6. 2003-07-25. PMID:12823074. |
research into the neuropharmacology of vomiting is providing insight into the ways substance p and serotonin interact within the central nervous system that could lead to additional applications of neurokinin-1 antagonists for the treatment of depression and stress. |
2003-07-25 |
2023-08-12 |
Not clear |
| Joseph Zohar, Harman Keegstra, Lucien Barrele. Fluvoxamine as effective as clomipramine against symptoms of severe depression: results from a multicentre, double-blind study. Human psychopharmacology. vol 18. issue 2. 2003-07-22. PMID:12590404. |
although selective serotonin reuptake inhibitors (ssris) are better tolerated than tricyclic antidepressants, their efficacy in severe depression remains to be further elucidated. |
2003-07-22 |
2023-08-12 |
Not clear |
| Mirjami Pelkonen, Mauri Marttune. Child and adolescent suicide: epidemiology, risk factors, and approaches to prevention. Paediatric drugs. vol 5. issue 4. 2003-07-22. PMID:12662120. |
although studies on the effectiveness of selective serotonin reuptake inhibitors are limited in number, evidence supports their use as first-line antidepressant medication in youth depression. |
2003-07-22 |
2023-08-12 |
Not clear |
| Ciaran Mulholland, Gerard Lynch, David J King, Stephen J Coope. A double-blind, placebo-controlled trial of sertraline for depressive symptoms in patients with stable, chronic schizophrenia. Journal of psychopharmacology (Oxford, England). vol 17. issue 1. 2003-07-22. PMID:12680747. |
there have been no studies specifically examining the efficacy of selective serotonin reuptake inhibitor antidepressants for the symptoms of depression in schizophrenia. |
2003-07-22 |
2023-08-12 |
Not clear |
| N K Khabibullina, A V Shakirzyanova, A I Skorinkin, R A Afzalov, R A Giniatulli. Serotonin modulates neuromuscular transmission in frogs. Bulletin of experimental biology and medicine. vol 134. issue 1. 2003-07-17. PMID:12459855. |
serotonin produced no effect on end-plate currents during low frequency electrical stimulation of the motor nerve, but increased the amplitude depression of multiquantal currents during high-frequency stimulation similar to motor commands fired by motoneurons. |
2003-07-17 |
2023-08-12 |
Not clear |
| Rosana G Peñalva, Marike Lancel, Cornelia Flachskamm, Johannes M H M Reul, Florian Holsboer, Astrid C E Linthors. Effect of sleep and sleep deprivation on serotonergic neurotransmission in the hippocampus: a combined in vivo microdialysis/EEG study in rats. The European journal of neuroscience. vol 17. issue 9. 2003-07-16. PMID:12752789. |
given the putative role of 5-ht in the aetiology of depression and the therapeutical efficacy of selective serotonin reuptake inhibitors in this illness, we also studied hippocampal 5-ht during 4 h of sd and during the subsequent recovery period. |
2003-07-16 |
2023-08-12 |
rat |
| J L Rausch, M E Johnson, K M Corley, H M Hobby, N Shendarkar, Y Fei, V Ganapathy, F H Leibac. Depressed patients have higher body temperature: 5-HT transporter long promoter region effects. Neuropsychobiology. vol 47. issue 3. 2003-07-03. PMID:12759553. |
depression has been associated with a decrease in intracellular serotonin (5-ht) reuptake through its transporter, sert. |
2003-07-03 |
2023-08-12 |
Not clear |
| Henner Giedk. On the role of serotonin in sleep regulation and depression. A commentary on "Neurobiological bases for the relation between sleep and depression" (J. Adrien). Sleep medicine reviews. vol 7. issue 1. 2003-07-01. PMID:12586533. |
on the role of serotonin in sleep regulation and depression. |
2003-07-01 |
2023-08-12 |
Not clear |
| John F Grede. Physical symptoms of depression: unmet needs. The Journal of clinical psychiatry. vol 64 Suppl 7. 2003-07-01. PMID:12755646. |
serotonin and norepinephrine may be shared neurochemical links that tie depression and physical symptoms together. |
2003-07-01 |
2023-08-12 |
Not clear |