| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shu-chi Hsiung, Mella Adlersberg, Victoria Arango, J John Mann, Hadassah Tamir, Kuo-peing Li. Attenuated 5-HT1A receptor signaling in brains of suicide victims: involvement of adenylyl cyclase, phosphatidylinositol 3-kinase, Akt and mitogen-activated protein kinase. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969265. |
positron emission tomography studies in major depression show reduced serotonin (5-ht)1a receptor antagonist-binding potentials in many brain regions including occipital cortex. |
2003-11-12 |
2023-08-12 |
human |
| Daniel Reyes-Haro, Guadalupe García-Alcocer, Ricardo Miledi, Jesús García-Colung. Uptake of serotonin by adult rat corpus callosum is partially reduced by common antidepressants. Journal of neuroscience research. vol 74. issue 1. 2003-11-10. PMID:13130511. |
the present data show that na(+)-dependent 5-ht uptake occurs in the cc and optic nerve and that this uptake is partially sensitive to antidepressants and probably mediated by the serotonin transporter, which may be relevant during depression. |
2003-11-10 |
2023-08-12 |
rat |
| Marc J Kaufman, Michael E Henry, Blaise deB Frederick, John Hennen, Rosemond A Villafuerte, Eve P Stoddard, Mark E Schmidt, Bruce M Cohen, Perry F Rensha. Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. Biological psychiatry. vol 54. issue 5. 2003-11-07. PMID:12946882. |
the selective serotonin reuptake inhibitor (ssri) discontinuation syndrome (ds) is an important potential complication of treatment for major depression. |
2003-11-07 |
2023-08-12 |
human |
| N Z Lu, A J Eshleman, A Janowsky, C L Bethe. Ovarian steroid regulation of serotonin reuptake transporter (SERT) binding, distribution, and function in female macaques. Molecular psychiatry. vol 8. issue 3. 2003-11-04. PMID:12660809. |
the serotonin reuptake transporter (sert) plays an important role in serotonin neurotransmission and in several psychopathological disorders such as depression and anxiety disorders. |
2003-11-04 |
2023-08-12 |
Not clear |
| Mikael Landén, Elias Eriksso. How does premenstrual dysphoric disorder relate to depression and anxiety disorders? Depression and anxiety. vol 17. issue 3. 2003-11-04. PMID:12768646. |
supporting both these notions, the treatment of choice for pmdd, the serotonin reuptake inhibitors (sris), is also first line of treatment for depression and for most anxiety disorders. |
2003-11-04 |
2023-08-12 |
human |
| P Polla. [Psychic disorders]. Revue neurologique. vol 158 Spec no 1. 2003-10-30. PMID:12690672. |
it is suggested that the first-line treatment of depression in parkinson's disease is the class of the selective serotonin reuptake inhibitors. |
2003-10-30 |
2023-08-12 |
Not clear |
| Nancy E E Van Loey, Maarten J M Van So. Psychopathology and psychological problems in patients with burn scars: epidemiology and management. American journal of clinical dermatology. vol 4. issue 4. 2003-10-23. PMID:12680803. |
from general trauma literature, it is concluded that cognitive (behavioral) and pharmacological (selective serotonin reuptake inhibitors) interventions have a positive effect on depression. |
2003-10-23 |
2023-08-12 |
human |
| Murray Alpert, Raul R Silva, Enrique R Pouge. Prediction of treatment response in geriatric depression from baseline folate level: interaction with an SSRI or a tricyclic antidepressant. Journal of clinical psychopharmacology. vol 23. issue 3. 2003-10-23. PMID:12826993. |
one hypothesis consistent with this is that fol deficiency causes a lowering of cns serotonin that contributes to depression. |
2003-10-23 |
2023-08-12 |
Not clear |
| Nela Pivac, Dorotea Mück-Seler, Marina Sagud, Miro Jakovljević, Maja Mustapić, Alma Mihaljević-Pele. Long-term sertraline treatment and peripheral biochemical markers in female depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 5. 2003-10-23. PMID:12921906. |
peripheral biochemical markers, platelet serotonin (5-ht) and platelet monoamine oxidase (mao) activity were determined spectrofluorimetrically at baseline and after 4 and 24 weeks of sertraline (a selective serotonin reuptake inhibitor (ssri)) treatment in 15 female nonsuicidal, nonpsychotic patients with major depression and compared with 15 drug-free healthy women. |
2003-10-23 |
2023-08-12 |
human |
| Nela Pivac, Dorotea Mück-Seler, Marina Sagud, Miro Jakovljević, Maja Mustapić, Alma Mihaljević-Pele. Long-term sertraline treatment and peripheral biochemical markers in female depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 5. 2003-10-23. PMID:12921906. |
the aim of the study was to determine the effects of 4 and 24 weeks of sertraline treatment on platelet 5-ht concentration and platelet mao activity in depressed patients subdivided according to the treatment response into remitters, responders and nonresponders after 4 and 24 weeks of sertraline treatment based on the 70%, 50-69% and <49% reductions in baseline montgomery-asperg depression rating scale (madrs) scores, respectively. |
2003-10-23 |
2023-08-12 |
human |
| S N Seidman, S P Roos. Sexual dysfunction and depression. Current psychiatry reports. vol 3. issue 3. 2003-10-21. PMID:11353583. |
interest in the relationship between sexual dysfunction and depression has risen substantially, prompted primarily by 1) the 1998 food and drug administration approval of sildenafil citrate as the first oral therapy of erectile dysfunction, and 2) the widespread clinical use of selective serotonin reuptake inhibitors, which prominently impair orgasm, and possibly libido and arousal. |
2003-10-21 |
2023-08-12 |
Not clear |
| Beverly H Brummett, Ilene C Siegler, Douglas R McQuoid, Ingrid K Svenson, Douglas A Marchuk, David C Steffen. Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. Psychiatric genetics. vol 13. issue 1. 2003-10-21. PMID:12605095. |
associations among the neo personality inventory, revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. |
2003-10-21 |
2023-08-12 |
Not clear |
| Beverly H Brummett, Ilene C Siegler, Douglas R McQuoid, Ingrid K Svenson, Douglas A Marchuk, David C Steffen. Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. Psychiatric genetics. vol 13. issue 1. 2003-10-21. PMID:12605095. |
the short variant of the serotonin transporter gene-linked functional polymorphic region (5-httlpr) has been associated with personality traits related to anxiety, hostility, and depression. |
2003-10-21 |
2023-08-12 |
Not clear |
| Dorotea Mück-Seler, Nela Pivac, Miro Jakovljević, Marina Sagud, Alma Mihaljević-Pele. Platelet 5-HT concentration and comorbid depression in war veterans with and without posttraumatic stress disorder. Journal of affective disorders. vol 75. issue 2. 2003-10-17. PMID:12798257. |
platelet 5-ht concentration and comorbid depression in war veterans with and without posttraumatic stress disorder. |
2003-10-17 |
2023-08-12 |
Not clear |
| Dorotea Mück-Seler, Nela Pivac, Miro Jakovljević, Marina Sagud, Alma Mihaljević-Pele. Platelet 5-HT concentration and comorbid depression in war veterans with and without posttraumatic stress disorder. Journal of affective disorders. vol 75. issue 2. 2003-10-17. PMID:12798257. |
the present study focused on platelet serotonin (5-ht) concentration and symptoms of comorbid depression in war veterans with or without ptsd. |
2003-10-17 |
2023-08-12 |
Not clear |
| Kouichi Kanetani, Mahito Kimura, Shunkichi End. Therapeutic effects of milnacipran (serotonin noradrenalin reuptake inhibitor) on depression following mild and moderate traumatic brain injury. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 70. issue 4. 2003-10-17. PMID:12928711. |
therapeutic effects of milnacipran (serotonin noradrenalin reuptake inhibitor) on depression following mild and moderate traumatic brain injury. |
2003-10-17 |
2023-08-12 |
Not clear |
| Kouichi Kanetani, Mahito Kimura, Shunkichi End. Therapeutic effects of milnacipran (serotonin noradrenalin reuptake inhibitor) on depression following mild and moderate traumatic brain injury. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 70. issue 4. 2003-10-17. PMID:12928711. |
the present study investigated the efficacy and safety of milnacipran, a serotonin noradrenalin reuptake inhibitor (snri), for the treatment of depression following mild and moderate traumatic brain injury (mmtbi). |
2003-10-17 |
2023-08-12 |
Not clear |
| Kouichi Kanetani, Mahito Kimura, Shunkichi End. Therapeutic effects of milnacipran (serotonin noradrenalin reuptake inhibitor) on depression following mild and moderate traumatic brain injury. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 70. issue 4. 2003-10-17. PMID:12928711. |
while other reports have been published on the use of antidepressants such as selective serotonin reuptake inhibitors (ssris) and tricyclics for the treatment of depression following mmtbi, no previous study has examined the use of a snri for this condition. |
2003-10-17 |
2023-08-12 |
Not clear |
| Sylvie Lemonde, Gustavo Turecki, David Bakish, Lisheng Du, Pavel D Hrdina, Christopher D Bown, Adolfo Sequeira, Neena Kushwaha, Stephen J Morris, Ajoy Basak, Xiao-Ming Ou, Paul R Alber. Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 25. 2003-10-14. PMID:14507979. |
impaired repression at a 5-hydroxytryptamine 1a receptor gene polymorphism associated with major depression and suicide. |
2003-10-14 |
2023-08-12 |
drosophila_melanogaster |
| Mike Brile. New hope in the treatment of painful symptoms in depression. Current opinion in investigational drugs (London, England : 2000). vol 4. issue 1. 2003-10-10. PMID:12625027. |
in primary care, physical symptoms such as pain, are the principal presenting symptoms, and a common psychopharmacology between pain and depression suggests that compounds that inhibit the reuptake of both serotonin and norepinephrine are likely to produce the greatest relief from depression and chronic pain. |
2003-10-10 |
2023-08-12 |
Not clear |