| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Darlene H Moak, Raymond F Anton, Patricia K Latham, Konstantin E Voronin, Randolph L Waid, Ramon Durazo-Arviz. Sertraline and cognitive behavioral therapy for depressed alcoholics: results of a placebo-controlled trial. Journal of clinical psychopharmacology. vol 23. issue 6. 2004-03-19. PMID:14624185. |
selective serotonin reuptake inhibitors (ssris) are effective in the treatment of depression and also had decreased drinking in some studies of heavy drinkers and alcoholics. |
2004-03-19 |
2023-08-12 |
human |
| Bárbara Arias, Rosa Catalán, Cristóbal Gastó, Blanca Gutiérrez, Lourdes Fañaná. 5-HTTLPR polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-weeks follow up study. Journal of clinical psychopharmacology. vol 23. issue 6. 2004-03-19. PMID:14624186. |
5-httlpr polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-weeks follow up study. |
2004-03-19 |
2023-08-12 |
Not clear |
| Michael P Jankowski, Susan R Sesac. Prefrontal cortical projections to the rat dorsal raphe nucleus: ultrastructural features and associations with serotonin and gamma-aminobutyric acid neurons. The Journal of comparative neurology. vol 468. issue 4. 2004-03-18. PMID:14689484. |
these results provide potential anatomical substrates whereby the pfc can both directly and indirectly regulate the activity of serotonin neurons in the drn and possibly contribute to the pathophysiology of depression. |
2004-03-18 |
2023-08-12 |
human |
| Andrew Herxheime. Treating major depression in children and adolescents: use of selective serotonin reuptake inhibitors needs urgent clarification. BMJ (Clinical research ed.). vol 328. issue 7438. 2004-03-18. PMID:14988211. |
treating major depression in children and adolescents: use of selective serotonin reuptake inhibitors needs urgent clarification. |
2004-03-18 |
2023-08-12 |
Not clear |
| Sylvie Lemonde, Anastasia Rogaeva, Paul R Alber. Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene. Journal of neurochemistry. vol 88. issue 4. 2004-03-15. PMID:14756806. |
regulation of serotonin (5-ht)1a receptor expression in brain is implicated in mood disorders such as depression and anxiety. |
2004-03-15 |
2023-08-12 |
human |
| Willy L Bonkale, Shayna Murdock, Janine E Janosky, Mark C Austi. Normal levels of tryptophan hydroxylase immunoreactivity in the dorsal raphe of depressed suicide victims. Journal of neurochemistry. vol 88. issue 4. 2004-03-15. PMID:14756817. |
many factors influence and regulate serotonin synthesis, and it is conceivable that alterations exist at other levels of regulation of serotonin biosynthesis in depression. |
2004-03-15 |
2023-08-12 |
human |
| Ennapadam S Krishnamoorth. Treatment of depression in patients with epilepsy: problems, pitfalls, and some solutions. Epilepsy & behavior : E&B. vol 4 Suppl 3. 2004-03-11. PMID:14592640. |
antidepressant drugs, including tricyclics and selective serotonin reuptake inhibitors, can be used to treat patients with epilepsy and comorbid depression. |
2004-03-11 |
2023-08-12 |
Not clear |
| R Ramasubb. Serotonin transporter gene functional polymorphism: a plausible candidate gene for increased vascular risk in depression. Medical hypotheses. vol 61. issue 1. 2004-03-10. PMID:12781638. |
serotonin transporter gene functional polymorphism: a plausible candidate gene for increased vascular risk in depression. |
2004-03-10 |
2023-08-12 |
Not clear |
| J Roy. [Depressive disorders in children and adolescents]. Anales del sistema sanitario de Navarra. vol 25 Suppl 3. 2004-03-10. PMID:12861248. |
recent research into the treatment of depression in children and adolescents has been focused on the effectiveness of cognitive-behavioural therapy and selective serotonin reuptake inhibitors. |
2004-03-10 |
2023-08-12 |
Not clear |
| Thomas E Joiner, Frank Johnson, Ken Soderstrom, Jessica S Brow. Is there an association between serotonin transporter gene polymorphism and family history of depression? Journal of affective disorders. vol 77. issue 3. 2004-03-09. PMID:14612228. |
is there an association between serotonin transporter gene polymorphism and family history of depression? |
2004-03-09 |
2023-08-12 |
Not clear |
| Thomas E Joiner, Frank Johnson, Ken Soderstrom, Jessica S Brow. Is there an association between serotonin transporter gene polymorphism and family history of depression? Journal of affective disorders. vol 77. issue 3. 2004-03-09. PMID:14612228. |
to date, research examining the relationship between the serotonin transporter gene and depression has yielded both positive and negative results. |
2004-03-09 |
2023-08-12 |
Not clear |
| Thomas E Joiner, Frank Johnson, Ken Soderstrom, Jessica S Brow. Is there an association between serotonin transporter gene polymorphism and family history of depression? Journal of affective disorders. vol 77. issue 3. 2004-03-09. PMID:14612228. |
this study will attempt to add further evidence to that body of literature by examining the relationship between the serotonin transporter gene and a family history of depression while controlling for a family history of completed suicide. |
2004-03-09 |
2023-08-12 |
Not clear |
| G Rubio, L San, F López-Munoz, P García-García, C Alam. [Combination therapy with reboxetine for major depression patients who are partial or nonresponders to serotonin selective reuptake inhibitors]. Actas espanolas de psiquiatria. vol 31. issue 6. 2004-03-08. PMID:14639507. |
[combination therapy with reboxetine for major depression patients who are partial or nonresponders to serotonin selective reuptake inhibitors]. |
2004-03-08 |
2023-08-12 |
Not clear |
| Tracy M Felton, Tommy B Kang, Stephan Hjorth, Sidney B Auerbac. Effects of selective serotonin and serotonin/noradrenaline reuptake inhibitors on extracellular serotonin in rat diencephalon and frontal cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 367. issue 3. 2004-02-24. PMID:12644903. |
some clinical reports suggest that tricyclic antidepressants which block both noradrenaline and serotonin (5-ht) reuptake (snris) are more effective than selective 5-ht reuptake inhibitors (ssris) in treating severe depression. |
2004-02-24 |
2023-08-12 |
rat |
| S Akhondzadeh, H Faraji, M Sadeghi, K Afkham, H Fakhrzadeh, A Kamalipou. Double-blind comparison of fluoxetine and nortriptyline in the treatment of moderate to severe major depression. Journal of clinical pharmacy and therapeutics. vol 28. issue 5. 2004-02-24. PMID:14632962. |
some psychiatrists have the impression that selective serotonin re-uptake inhibitors may not work as well as tricyclic anti-depressants in severe depression and/or melancholia. |
2004-02-24 |
2023-08-12 |
Not clear |
| Thomas Frodl, Eva M Meisenzahl, Peter Zill, Thomas Baghai, Dan Rujescu, Gerda Leinsinger, Ronald Bottlender, Cornelius Schüle, Peter Zwanzger, Rolf R Engel, Rainer Rupprecht, Brigitta Bondy, Maximilian Reiser, Hans-Jürgen Mölle. Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. Archives of general psychiatry. vol 61. issue 2. 2004-02-24. PMID:14757594. |
reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. |
2004-02-24 |
2023-08-12 |
Not clear |
| Thomas Frodl, Eva M Meisenzahl, Peter Zill, Thomas Baghai, Dan Rujescu, Gerda Leinsinger, Ronald Bottlender, Cornelius Schüle, Peter Zwanzger, Rolf R Engel, Rainer Rupprecht, Brigitta Bondy, Maximilian Reiser, Hans-Jürgen Mölle. Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. Archives of general psychiatry. vol 61. issue 2. 2004-02-24. PMID:14757594. |
substantial evidence supports a role for dysfunction of the serotonin transporter in the pathogenesis of major depression. |
2004-02-24 |
2023-08-12 |
Not clear |
| S Hesse, H Barthel, W Hermann, T Murai, R Kluge, A Wagner, O Sabri, B Egger. Regional serotonin transporter availability and depression are correlated in Wilson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 8. 2004-02-19. PMID:12898347. |
regional serotonin transporter availability and depression are correlated in wilson's disease. |
2004-02-19 |
2023-08-12 |
Not clear |
| Gary R Morrow, Jane T Hickok, Joseph A Roscoe, Richard F Raubertas, Paul L R Andrews, Patrick J Flynn, Harry E Hynes, Tarit K Banerjee, Jeffrey J Kirshner, David K Kin. Differential effects of paroxetine on fatigue and depression: a randomized, double-blind trial from the University of Rochester Cancer Center Community Clinical Oncology Program. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. vol 21. issue 24. 2004-02-13. PMID:14673053. |
fatigue and depression typically occur together in cancer patients, suggesting a common etiology, perhaps based on serotonin. |
2004-02-13 |
2023-08-12 |
Not clear |
| Gary R Morrow, Jane T Hickok, Joseph A Roscoe, Richard F Raubertas, Paul L R Andrews, Patrick J Flynn, Harry E Hynes, Tarit K Banerjee, Jeffrey J Kirshner, David K Kin. Differential effects of paroxetine on fatigue and depression: a randomized, double-blind trial from the University of Rochester Cancer Center Community Clinical Oncology Program. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. vol 21. issue 24. 2004-02-13. PMID:14673053. |
this randomized clinical trial tested whether paroxetine, a selective serotonin reuptake inhibitor antidepressant known to modulate brain serotonin, would reduce fatigue in cancer patients and whether any reduction was related to depression. |
2004-02-13 |
2023-08-12 |
Not clear |