| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carolyn W Harle. Norepinephrine and serotonin axonal dynamics and clinical depression: a commentary on the interaction between serotonergic and noradrenergic axons during axonal regeneration. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637074. |
norepinephrine and serotonin axonal dynamics and clinical depression: a commentary on the interaction between serotonergic and noradrenergic axons during axonal regeneration. |
2004-01-05 |
2023-08-12 |
Not clear |
| Ying Liu, Yoshiyuki Ishida, Koh Shinoda, Shoji Nakamur. Interaction between serotonergic and noradrenergic axons during axonal regeneration. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637090. |
the differential roles of 5-ht and na axons in axonal regeneration may play a role in a variety of physiological functions related to these monoamines and possibly in the pathophysiology of clinical depression. |
2004-01-05 |
2023-08-12 |
rat |
| Andrew Holmes, Dennis L Murphy, Jacqueline N Crawle. Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biological psychiatry. vol 54. issue 10. 2003-12-29. PMID:14625137. |
abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. |
2003-12-29 |
2023-08-12 |
mouse |
| Andrew Holmes, Dennis L Murphy, Jacqueline N Crawle. Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biological psychiatry. vol 54. issue 10. 2003-12-29. PMID:14625137. |
evidence of a link between genetic variation of the serotonin transporter and depression and anxiety prompted the generation of serotonin transporter knockout mice. |
2003-12-29 |
2023-08-12 |
mouse |
| Feng Chen, Amir H Rezvani, Andrew J Lawrenc. Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment. Naunyn-Schmiedeberg's archives of pharmacology. vol 367. issue 2. 2003-12-23. PMID:12595953. |
the ability of sjw to affect 5-ht, dopamine and opioid systems in mesolimbic regions in the cns, either by a direct or by indirect (adaptation) mechanism, may help to explain the efficacy of sjw in the treatment of depression clinically and in some of the behavioural effects observed in experimental rodents. |
2003-12-23 |
2023-08-12 |
rat |
| Saoussen Bouali, Alexis Evrard, Michel Chastanet, Klaus-Peter Lesch, Michel Hamon, Joëlle Adrie. Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter. The European journal of neuroscience. vol 18. issue 8. 2003-12-23. PMID:14622181. |
the differential effects of testosterone and estradiol on 5-ht1a-mediated control of 5-ht neurotransmission might be related to the well-established gender differences in the vulnerability to depression. |
2003-12-23 |
2023-08-12 |
mouse |
| F Lopez-Rodriguez, C L Wilson, N T Maidment, R E Poland, J Enge. Total sleep deprivation increases extracellular serotonin in the rat hippocampus. Neuroscience. vol 121. issue 2. 2003-12-19. PMID:14522011. |
in this report we tested the hypothesis that total sleep deprivation induces an increase in extracellular serotonin (5-ht) levels in the hippocampus, a structure that has been proposed repeatedly to play a role in the pathophysiology of depression. |
2003-12-19 |
2023-08-12 |
rat |
| Dan J Stein, Jonathan Davidson, Soraya Seedat, Katherine Beeb. Paroxetine in the treatment of post-traumatic stress disorder: pooled analysis of placebo-controlled studies. Expert opinion on pharmacotherapy. vol 4. issue 10. 2003-12-18. PMID:14521492. |
paroxetine is a selective serotonin re-uptake inhibitor that has been found effective in the treatment of major depression as well as a range of anxiety disorders. |
2003-12-18 |
2023-08-12 |
Not clear |
| George I Papakostas, Timothy Petersen, John J Worthington, Pamela A Roffi, Jonathan E Alpert, Maurizio Fava, Andrew A Nierenber. A pilot, open study of sertraline in outpatients with treatment-resistant depression (TRD) or with a history of TRD who responded but later relapsed. International clinical psychopharmacology. vol 18. issue 5. 2003-12-16. PMID:12920390. |
while most depressed patients are prescribed a selective serotonin reuptake inhibitor (ssri) as an initial treatment, the use of ssris as a second or third-line treatment for depression is not as prevalent. |
2003-12-16 |
2023-08-12 |
Not clear |
| Pedro L Delgado, Francisco A Moreno, Larry Onate, Alan J Gelenber. Sequential catecholamine and serotonin depletion in mirtazapine-treated depressed patients. The international journal of neuropsychopharmacology. vol 5. issue 1. 2003-12-12. PMID:12057033. |
both 5-ht and catecholamine depletion led to a partial return of depression in most patients. |
2003-12-12 |
2023-08-12 |
Not clear |
| Demian Barbas, Luc DesGroseillers, Vincent F Castellucci, Thomas J Carew, Stéphane Marinesc. Multiple serotonergic mechanisms contributing to sensitization in aplysia: evidence of diverse serotonin receptor subtypes. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 5. 2003-12-10. PMID:14557610. |
the neuronal circuits mediating defensive reflexes contain a number of interneurons that respond to 5-ht in ways opposite to those of the sns, showing a decrease in excitability and/or synaptic depression. |
2003-12-10 |
2023-08-12 |
aplysia |
| Thomas C Baghai, Cornelius Schule, Peter Zwanzger, Peter Zill, Robin Ella, Daniela Eser, Tobias Deiml, Christo Minov, Rainer Rupprecht, Brigitta Bond. No Influence of a functional polymorphism within the serotonin transporter gene on partial sleep deprivation in major depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 4. issue 3. 2003-12-09. PMID:12872203. |
no influence of a functional polymorphism within the serotonin transporter gene on partial sleep deprivation in major depression. |
2003-12-09 |
2023-08-12 |
Not clear |
| Thomas C Baghai, Cornelius Schule, Peter Zwanzger, Peter Zill, Robin Ella, Daniela Eser, Tobias Deiml, Christo Minov, Rainer Rupprecht, Brigitta Bond. No Influence of a functional polymorphism within the serotonin transporter gene on partial sleep deprivation in major depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 4. issue 3. 2003-12-09. PMID:12872203. |
thus, the previously reported influence of the serotonin transporter gene on psd outcome in bipolar depression could not be confirmed in unipolar depressed patients. |
2003-12-09 |
2023-08-12 |
Not clear |
| Phil Skolnick, Piotr Popik, Aaron Janowsky, Bernard Beer, Arnold S Lipp. "Broad spectrum" antidepressants: is more better for the treatment of depression? Life sciences. vol 73. issue 25. 2003-11-25. PMID:14561522. |
"broad spectrum" antidepressants are compounds that inhibit the reuptake of norepinephrine, serotonin and dopamine, the three biogenic amines most closely linked to depression. |
2003-11-25 |
2023-08-12 |
human |
| Zubin Bhagwagar, Andrew J Montgomery, Paul M Grasby, Philip J Cowe. Lack of effect of a single dose of hydrocortisone on serotonin(1A) receptors in recovered depressed patients measured by positron emission tomography with [11C]WAY-100635. Biological psychiatry. vol 54. issue 9. 2003-11-21. PMID:14573316. |
elevated cortisol levels might account for the reduction in central serotonin 1a (5-hydroxytryptamine [5-ht](1a)) receptor binding and function observed in patients with major depression. |
2003-11-21 |
2023-08-12 |
human |
| Zubin Bhagwagar, Andrew J Montgomery, Paul M Grasby, Philip J Cowe. Lack of effect of a single dose of hydrocortisone on serotonin(1A) receptors in recovered depressed patients measured by positron emission tomography with [11C]WAY-100635. Biological psychiatry. vol 54. issue 9. 2003-11-21. PMID:14573316. |
we tested this hypothesis by studying the effect of acute administration of hydrocortisone on 5-ht(1a) receptor binding potential (bp) in subjects recovered from depression. |
2003-11-21 |
2023-08-12 |
human |
| Maurizio Fava, Patrick J McGrath, Wang-Pui She. Switching to reboxetine: an efficacy and safety study in patients with major depressive disorder unresponsive to fluoxetine. Journal of clinical psychopharmacology. vol 23. issue 4. 2003-11-20. PMID:12920412. |
the aim of the present study was to evaluate the efficacy and safety of an immediate switch to reboxetine, a selective noradrenaline reuptake inhibitor (selective nri), in patients with depression unresponsive to the selective serotonin reuptake inhibitor (ssri) fluoxetine. |
2003-11-20 |
2023-08-12 |
Not clear |
| Kyu-Sung Lee, Yong-Gil Na, Travis Dean-McKinney, Adam P Klausner, Jeremy B Tuttle, William D Steer. Alterations in voiding frequency and cystometry in the clomipramine induced model of endogenous depression and reversal with fluoxetine. The Journal of urology. vol 170. issue 5. 2003-11-20. PMID:14532855. |
because serotonin (5-ht) in the central nervous system may inhibit bladder activity, we postulated that depression associated with altered 5-ht function might be associated with overactive bladder (oab). |
2003-11-20 |
2023-08-12 |
rat |
| Kyu-Sung Lee, Yong-Gil Na, Travis Dean-McKinney, Adam P Klausner, Jeremy B Tuttle, William D Steer. Alterations in voiding frequency and cystometry in the clomipramine induced model of endogenous depression and reversal with fluoxetine. The Journal of urology. vol 170. issue 5. 2003-11-20. PMID:14532855. |
we examined a rat model of endogenous depression caused by lowering 5-ht for effects on voiding frequency (vf) and awake cystometry (cmg), and examined the effect of reversal using the selective serotonin reuptake inhibitor fluoxetine. |
2003-11-20 |
2023-08-12 |
rat |
| Michal Shayit, Gal Yadid, David H Overstreet, Aron Welle. 5-HT(1A) receptor subsensitivity in infancy and supersensitivity in adulthood in an animal model of depression. Brain research. vol 980. issue 1. 2003-11-12. PMID:12865163. |
5-ht(1a) receptor subsensitivity in infancy and supersensitivity in adulthood in an animal model of depression. |
2003-11-12 |
2023-08-12 |
rat |