| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marc Steffens, Thomas J Feuerstei. Receptor-independent depression of DA and 5-HT uptake by cannabinoids in rat neocortex--involvement of Na(+)/K(+)-ATPase. Neurochemistry international. vol 44. issue 7. 2004-07-28. PMID:15209421. |
receptor-independent depression of da and 5-ht uptake by cannabinoids in rat neocortex--involvement of na(+)/k(+)-atpase. |
2004-07-28 |
2023-08-12 |
rat |
| Yusong Guo, Lingdong Kong, Yemin Wang, Zhiqi Huan. Antidepressant evaluation of polysaccharides from a Chinese herbal medicine Banxia-houpu decoction. Phytotherapy research : PTR. vol 18. issue 3. 2004-07-20. PMID:15103666. |
the results indicate that the mode of action of polysaccharides from banxia-houpu decoction in depression might be related to both 5-ht and da systems. |
2004-07-20 |
2023-08-12 |
mouse |
| C Barbui, G Guaiana, M Hotop. Amitriptyline for inpatients and SSRIs for outpatients with depression? Systematic review and meta-regression analysis. Pharmacopsychiatry. vol 37. issue 3. 2004-07-19. PMID:15179966. |
although the selective serotonin reuptake inhibitors (ssris) are widely used as first-line agents in depression, amitriptyline, a reference tricyclic (tca) agent, has the edge in terms of efficacy over control antidepressants (ads), but it is not clear whether this advantage can be attributed to a more favourable profile in inpatients, but not in outpatients, with depression. |
2004-07-19 |
2023-08-12 |
Not clear |
| N Ozaki, D Goldman, W H Kaye, K Plotnicov, B D Greenberg, J Lappalainen, G Rudnick, D L Murph. Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Molecular psychiatry. vol 8. issue 11. 2004-07-16. PMID:14593431. |
two common serotonin transporter (sert) untranslated region gene variants have been intensively studied, but remain inconclusively linked to depression and other neuropsychiatric disorders. |
2004-07-16 |
2023-08-12 |
Not clear |
| M Willeit, N Praschak-Rieder, A Neumeister, P Zill, F Leisch, J Stastny, E Hilger, N Thierry, A Konstantinidis, D Winkler, K Fuchs, W Sieghart, H Aschauer, M Ackenheil, B Bondy, S Kaspe. A polymorphism (5-HTTLPR) in the serotonin transporter promoter gene is associated with DSM-IV depression subtypes in seasonal affective disorder. Molecular psychiatry. vol 8. issue 11. 2004-07-16. PMID:14593433. |
a polymorphism (5-httlpr) in the serotonin transporter promoter gene is associated with dsm-iv depression subtypes in seasonal affective disorder. |
2004-07-16 |
2023-08-12 |
human |
| David E Adson, Matt G Kushner, Kathryn M Eiben, S Charles Schul. Preliminary experience with adjunctive quetiapine in patients receiving selective serotonin reuptake inhibitors. Depression and anxiety. vol 19. issue 2. 2004-07-15. PMID:15022147. |
treatment of depression and anxiety disorders with selective serotonin reuptake inhibitors (ssris) has been shown by numerous studies to be generally effective. |
2004-07-15 |
2023-08-12 |
Not clear |
| Sarah Aronson, Pedro Delgad. Escitalopram. Drugs of today (Barcelona, Spain : 1998). vol 40. issue 2. 2004-07-13. PMID:15045034. |
escitalopram, a selective serotonin reuptake inhibitor (ssri) was recently approved by the united states food and drug administration (fda) for the treatment of major depression. |
2004-07-13 |
2023-08-12 |
Not clear |
| Frank G Gilliam, Juan Santos, Victoria Vahle, Jewell Carter, Kelly Brown, Hrvoje Hecimovi. Depression in epilepsy: ignoring clinical expression of neuronal network dysfunction? Epilepsia. vol 45 Suppl 2. 2004-07-13. PMID:15186342. |
although the density of serotonin receptors is greatest in limbic brain regions commonly involved in human epilepsy, such as the mesial temporal and prefrontal areas, no prior randomized controlled trials have evaluated the efficacy of serotonin reuptake inhibitors for depression in epilepsy. |
2004-07-13 |
2023-08-12 |
human |
| A M Myint, Y K Ki. Cytokine-serotonin interaction through IDO: a neurodegeneration hypothesis of depression. Medical hypotheses. vol 61. issue 5-6. 2004-07-06. PMID:14592780. |
the interaction between brain 5-ht level and the activity of its autoreceptors plays a role in mood changes and depression. |
2004-07-06 |
2023-08-12 |
Not clear |
| Patricia K Corey-Lisle, Rowena Nash, Paul Stang, Ralph Swindl. Response, partial response, and nonresponse in primary care treatment of depression. Archives of internal medicine. vol 164. issue 11. 2004-07-06. PMID:15197045. |
this study identifies factors related to poor response to depression treatment with selective serotonin reuptake inhibitors (ssris) in primary care settings by (1) examining clinical response taking into account treatment, (2) comparing baseline characteristics and outcomes between patients classified by response, and (3) examining characteristics predicting poor response. |
2004-07-06 |
2023-08-12 |
Not clear |
| Phebe Tucker, Katherine L Beebe, Christie Burgin, Dorothy B Wyatt, Don E Parker, Barbara K Masters, Ola Nawa. Paroxetine treatment of depression with posttraumatic stress disorder: effects on autonomic reactivity and cortisol secretion. Journal of clinical psychopharmacology. vol 24. issue 2. 2004-07-06. PMID:15206659. |
results demonstrate that sampled comorbid patients had autonomic reactivity patterns similar to ptsd that responded to selective serotonin reuptake inhibitor treatment but had diurnal cortisol secretion patterns different from depression or that expected for ptsd, which did not change with treatment. |
2004-07-06 |
2023-08-12 |
human |
| Pavel A Petukhov, Jianrong Zhang, Cheng Z Wang, Yan Ping Ye, Kenneth M Johnson, Alan P Kozikowsk. Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring. Journal of medicinal chemistry. vol 47. issue 12. 2004-07-02. PMID:15163183. |
the present results may have important implications for the elucidation of the structural differences between da, 5-ht, and ne transporters and for the further design of new leads for development of cocaine abuse medication as well as certain neurological disorders such as adhd and depression. |
2004-07-02 |
2023-08-12 |
Not clear |
| Roger S McIntyre, Claire O'Donova. The human cost of not achieving full remission in depression. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 49. issue 3 Suppl 1. 2004-07-01. PMID:15147032. |
available pharmacoeconomic data and randomized, controlled clinical trials published in the last 5 years identified through medline searches with terms including burden, cost, economics, serotonin reuptake inhibitors (also, specific agents), venlafaxine, nefazadone, mirtazapine, psychotherapy, remission, and depression were reviewed. |
2004-07-01 |
2023-08-12 |
human |
| Raymond W Lam, Sidney H Kenned. Evidence-based strategies for achieving and sustaining full remission in depression: focus on metaanalyses. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 49. issue 3 Suppl 1. 2004-07-01. PMID:15147033. |
strategies that have demonstrated improved rates of full remission in the treatment of depression include venlafaxine as initial antidepressant therapy, which has been shown to provide higher rates of remission when compared with serotonin reuptake inhibitors and tricyclic antidepressants. |
2004-07-01 |
2023-08-12 |
human |
| Kiran Rabher. Special issues in the management of depression in older patients. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 49. issue 3 Suppl 1. 2004-07-01. PMID:15147035. |
managing depression in older patients can be done effectively with the antidepressant therapies currently available, including selective serotonin reuptake inhibitors (ssris), venlafaxine, and mirtazapine. |
2004-07-01 |
2023-08-12 |
Not clear |
| Karen A Sawabini, Ray L Watt. Treatment of depression in Parkinson's disease. Parkinsonism & related disorders. vol 10 Suppl 1. 2004-06-29. PMID:15109585. |
the use of serotonin reuptake inhibitors and tricyclic antidepressants in the treatment of depression in pd is widespread in clinical practice. |
2004-06-29 |
2023-08-12 |
Not clear |
| Hiske M van der Stelt, Laus M Broersen, Berend Olivier, Herman G M Westenber. Effects of dietary tryptophan variations on extracellular serotonin in the dorsal hippocampus of rats. Psychopharmacology. vol 172. issue 2. 2004-06-28. PMID:14647968. |
there is evidence to suggest that the efficacy of selective serotonin reuptake inhibitors (ssris) in depression is dependent on the availability of serotonin (5-ht) in the brain. |
2004-06-28 |
2023-08-12 |
rat |
| Weidong Yang, Qingde Wang, Stephen J Kanes, John M Murray, Kazuko Nishikur. Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy. Brain research. Molecular brain research. vol 124. issue 1. 2004-06-28. PMID:15093687. |
altered rna editing of serotonin 5-ht2c receptor induced by interferon: implications for depression associated with cytokine therapy. |
2004-06-28 |
2023-08-12 |
human |
| Weidong Yang, Qingde Wang, Stephen J Kanes, John M Murray, Kazuko Nishikur. Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy. Brain research. Molecular brain research. vol 124. issue 1. 2004-06-28. PMID:15093687. |
it has been speculated that rna editing may play a role in several pharmacological and behavioral processes where the serotonergic plasticity is mediated through 5-ht(2c)r. interferon-alpha (ifn-alpha) often causes severe depression in patients treated for chronic viral hepatitis and certain malignancies. |
2004-06-28 |
2023-08-12 |
human |
| Weidong Yang, Qingde Wang, Stephen J Kanes, John M Murray, Kazuko Nishikur. Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy. Brain research. Molecular brain research. vol 124. issue 1. 2004-06-28. PMID:15093687. |
our results support the hypothesis that 5-ht(2c)r mrna editing has causative relevance in the pathophysiology of depression associated with cytokine therapy. |
2004-06-28 |
2023-08-12 |
human |