| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew D Krysta. Depression and insomnia in women. Clinical cornerstone. vol 6 Suppl 1B. 2004-11-16. PMID:15457812. |
medications related to the serotonin system-the selective serotonin reuptake inhibitors, or ssris-appear to be uniquely effective in the treatment of insomnia and depression experienced by women. |
2004-11-16 |
2023-08-12 |
Not clear |
| Aygun Ertugrul, James L Kennedy, Mario Masellis, Vincenzo S Basile, Karuna Jayathilake, Herbert Y Meltze. No association of the T102C polymorphism of the serotonin 2A receptor gene (HTR2A) with suicidality in schizophrenia. Schizophrenia research. vol 69. issue 2-3. 2004-11-15. PMID:15469201. |
additional evidence for a role of serotonin (5-ht) in the pathogenesis of suicidal behavior is provided by a recent report that the 5-ht2a (htr2a) t102c polymorphism was associated with suicidality in patients with major depression. |
2004-11-15 |
2023-08-12 |
Not clear |
| Tsunenori Hirayama, Tomoko Kobayashi, Takehisa Fujita, Osamu Fujin. [Two cases of adult Down syndrome treated with selective serotonin re-uptake inhibitor for behavior disorders]. No to hattatsu = Brain and development. vol 36. issue 5. 2004-11-09. PMID:15461027. |
selective serotonin re-uptake inhibitor (ssri) is effective for depression and panic disorders. |
2004-11-09 |
2023-08-12 |
Not clear |
| Anette Schra. Psychiatric aspects of Parkinson's disease--an update. Journal of neurology. vol 251. issue 7. 2004-10-20. PMID:15258780. |
depression is a common problem in early as well as advanced pd, and selective serotonin reuptake inhibitors, reboxetine, and tricyclic antidepressants have been reported to be effective and well tolerated antidepressants. |
2004-10-20 |
2023-08-12 |
Not clear |
| Prem Chopra, Chee Ng, Isaac Schweitze. Serotonin syndrome associated with fluoxetine and olanzapine. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 5. issue 2. 2004-10-14. PMID:15179671. |
this case report describes a patient with treatment-resistant depression treated with fluoxetine and olanzapine who developed serotonin syndrome. |
2004-10-14 |
2023-08-12 |
Not clear |
| Wolfgang Retz, Petra Retz-Junginger, Tillmann Supprian, Johannes Thome, Michael Rösle. Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathology. Behavioral sciences & the law. vol 22. issue 3. 2004-10-13. PMID:15211560. |
a deletion/insertion polymorphism within the 5-ht transporter (5-htt) promoter gene (5-htt gene-linked polymorphic region, 5-httlpr) is thought to be associated with several psychopathological phenotypes related to disturbed impulse control, anxiety and depression. |
2004-10-13 |
2023-08-12 |
Not clear |
| Mark Ansorge, Cornelia Tanneberger, Benjamin Davies, Franz Theuring, Heike Kussero. Analysis of the murine 5-HT receptor gene promoter in vitro and in vivo. The European journal of neuroscience. vol 20. issue 2. 2004-09-30. PMID:15233746. |
the expression level of the 5-ht(1a) receptor gene (htr1a) in the central nervous system (cns) is implicated in the aetiology and treatment of anxiety disorders and depression. |
2004-09-30 |
2023-08-12 |
mouse |
| Maria Nobile, Maria Giulia Cataldo, Roberto Giorda, Marco Battaglia, Cinzia Baschirotto, Monica Bellina, Cecilia Marino, Massimo Molten. A case-control and family-based association study of the 5-HTTLPR in pediatric-onset depressive disorders. Biological psychiatry. vol 56. issue 4. 2004-09-30. PMID:15312818. |
the aim of this work was to explore the possible association between childhood- and early-adolescent-onset dsm-iv depressive disorders (dd; including major depression and dysthymia) and the serotonin transporter-linked promoter polymorphism (5-httlpr) locus. |
2004-09-30 |
2023-08-12 |
Not clear |
| Rouzanna L Djavadia. Serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals. Acta neurobiologiae experimentalis. vol 64. issue 2. 2004-09-30. PMID:15366252. |
finally mechanisms by which serotonin and its receptors influence neurogenesis in the adult dg are summarized and hypotheses linking the decreased rate of dg neurogenesis with mechanisms of depression are discussed. |
2004-09-30 |
2023-08-12 |
Not clear |
| Geoffrey K Isbister, Steven J Bowe, Andrew Dawson, Ian M Whyt. Relative toxicity of selective serotonin reuptake inhibitors (SSRIs) in overdose. Journal of toxicology. Clinical toxicology. vol 42. issue 3. 2004-09-29. PMID:15362595. |
selective serotonin reuptake inhibitors (ssris) have increasingly replaced tricyclic antidepressants (tcas) in the treatment of depression. |
2004-09-29 |
2023-08-12 |
Not clear |
| Alexander Neumeiste. Tryptophan depletion, serotonin, and depression: where do we stand? Psychopharmacology bulletin. vol 37. issue 4. 2004-09-28. PMID:15131521. |
tryptophan depletion, serotonin, and depression: where do we stand? |
2004-09-28 |
2023-08-12 |
Not clear |
| Alexander Neumeiste. Tryptophan depletion, serotonin, and depression: where do we stand? Psychopharmacology bulletin. vol 37. issue 4. 2004-09-28. PMID:15131521. |
tryptophan depletion is a widely used paradigm to study serotonin system-related mechanisms in the pathophysiology and treatment of depression. |
2004-09-28 |
2023-08-12 |
Not clear |
| Alexander Neumeiste. Tryptophan depletion, serotonin, and depression: where do we stand? Psychopharmacology bulletin. vol 37. issue 4. 2004-09-28. PMID:15131521. |
the behavioral data in healthy controls with and without genetic risk for depression, and in patient populations during the symptomatic phase of depression and when being remitted, suggest a trait abnormality of serotonin function in depression and that antidepressants may compensate for the underlying deficit. |
2004-09-28 |
2023-08-12 |
Not clear |
| V Fenik, R O Davies, L Kubi. Combined antagonism of aminergic excitatory and amino acid inhibitory receptors in the XII nucleus abolishes REM sleep-like depression of hypoglossal motoneuronal activity. Archives italiennes de biologie. vol 142. issue 3. 2004-09-24. PMID:15260378. |
we conclude that the rem sleep-like depression of xii motoneuronal activity can be fully accounted for by all or some of the following mechanisms: a withdrawal of motoneuronal excitation mediated by norepinephrine and serotonin and increased inhibition mediated by gaba and glycine. |
2004-09-24 |
2023-08-12 |
rat |
| Christina S Barr, Timothy K Newman, Melanie Schwandt, Courtney Shannon, Rachel L Dvoskin, Stephen G Lindell, Julie Taubman, Bill Thompson, Maribeth Champoux, Klaus Peter Lesch, David Goldman, Stephen J Suomi, J Dee Higle. Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 33. 2004-09-23. PMID:15302939. |
a polymorphism in the human serotonin transporter gene promoter (5-httlpr) is associated with anxiety and increased risk for developing depression in the face of adversity. |
2004-09-23 |
2023-08-12 |
human |
| Robert N Golde. Making advances where it matters: improving outcomes in mood and anxiety disorders. CNS spectrums. vol 9. issue 6 Suppl 4. 2004-09-21. PMID:15181381. |
selective serotonin reuptake inhibitors (ssris) are safe and effective treatments for major depression and anxiety disorders, and have become the most widely prescribed antidepressants worldwide. |
2004-09-21 |
2023-08-12 |
Not clear |
| D A Slattery, A L Hudson, D J Nut. Invited review: the evolution of antidepressant mechanisms. Fundamental & clinical pharmacology. vol 18. issue 1. 2004-09-20. PMID:14748749. |
the identification of their mechanism of action, and those of reserpine and amphetamine, in the 1960s, led to the monoamine theories of depression being postulated; first, with noradrenaline then 5-hydroxytryptamine being considered the more important amine. |
2004-09-20 |
2023-08-12 |
Not clear |
| Andrew H Kemp, Marcus A Gray, Richard B Silberstein, Stuart M Armstrong, Pradeep J Natha. Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humans. NeuroImage. vol 22. issue 3. 2004-09-16. PMID:15219580. |
the serotonergic system is one of the major systems targeted in the pharmacological treatment of a wide range of mood disorders including depression; however, little is known about the neurophysiological mechanisms underlying the effects of serotonin (5-ht) on affective phenomena including emotional behaviours, mood and emotional processing. |
2004-09-16 |
2023-08-12 |
human |
| Riina Häidkind, Marika Eller, Ants Kask, Maarike Harro, Ago Rinken, Lars Oreland, Jaanus Harr. Increased behavioural activity of rats in forced swimming test after partial denervation of serotonergic system by parachloroamphetamine treatment. Neurochemistry international. vol 45. issue 5. 2004-09-16. PMID:15234115. |
these data suggest that partial 5-ht denervation with low doses of pca, which elicits a specific pattern of neurodegeneration, results in an increased behavioural activity, and that the traditional interpretation of the measures in forced swimming test, despite of the test's predictive power in revealing antidepressants acting on monoaminergic systems, is not adequate for studies on the neurochemical basis of depression. |
2004-09-16 |
2023-08-12 |
rat |
| X Henry Hu, Scott A Bull, Enid M Hunkeler, Eileen Ming, Janelle Y Lee, Bruce Fireman, Leona E Markso. Incidence and duration of side effects and those rated as bothersome with selective serotonin reuptake inhibitor treatment for depression: patient report versus physician estimate. The Journal of clinical psychiatry. vol 65. issue 7. 2004-09-13. PMID:15291685. |
incidence and duration of side effects and those rated as bothersome with selective serotonin reuptake inhibitor treatment for depression: patient report versus physician estimate. |
2004-09-13 |
2023-08-12 |
Not clear |