| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alan F Schatzber. Employing pharmacologic treatment of bipolar disorder to greatest effect. The Journal of clinical psychiatry. vol 65 Suppl 15. 2005-01-18. PMID:15554791. |
atypical antipsychotics with the dual effect of blocking dopamine and serotonin receptors in the brain decrease psychosis, mania, and, according to some preliminary indications, possibly depression. |
2005-01-18 |
2023-08-12 |
Not clear |
| b' Nela Pivac, Dorotea M\\xc3\\xbcck-Seler, Maja Mustapi\\xc4\\x87, Korona Nenadi\\xc4\\x87-Sviglin, Dragica Kozari\\xc4\\x87-Kovaci\\xc4\\x8. Platelet serotonin concentration in alcoholic subjects. Life sciences. vol 76. issue 5. 2005-01-18. PMID:15556165.' |
comorbid depression in female alcoholics slightly elevated platelet 5-ht levels but these values were still reduced compared to values in healthy women. |
2005-01-18 |
2023-08-12 |
human |
| Madelon Y Bolling, Robert J Kohlenber. Reasons for quitting serotonin reuptake inhibitor therapy: paradoxical psychological side effects and patient satisfaction. Psychotherapy and psychosomatics. vol 73. issue 6. 2005-01-14. PMID:15479994. |
the goal of this study was to document the existence of psychological side effects associated with serotonin reuptake inhibitors (ssris) taken for depression and to determine their relationship to patients' decisions to stop treatment, and attitudes toward taking ssris again. |
2005-01-14 |
2023-08-12 |
Not clear |
| Shripad B Deshpande, Archana Jh. Aglycemia and ischemia depress monosynaptic and polysynaptic reflexes in neonatal rat spinal cord in vitro by involving different types of 5-hydroxytryptamine receptors. Neuroscience letters. vol 372. issue 1-2. 2005-01-14. PMID:15531110. |
involvement of 5-hydroxytryptaminergic (5-ht) system for aglycemia- and ischemia-induced depression of the spinal reflexes was evaluated. |
2005-01-14 |
2023-08-12 |
rat |
| Shripad B Deshpande, Archana Jh. Aglycemia and ischemia depress monosynaptic and polysynaptic reflexes in neonatal rat spinal cord in vitro by involving different types of 5-hydroxytryptamine receptors. Neuroscience letters. vol 372. issue 1-2. 2005-01-14. PMID:15531110. |
spiperone (5-ht(2a) antagonist) and ketanserin, (5-ht(2a/2c) antagonist) blocked the aglycemia-induced depression of the reflexes completely while ondansetron (5-ht(3) antagonist) attenuated it partially (as abolition times were around 50 min). |
2005-01-14 |
2023-08-12 |
rat |
| Constance Holde. Neuroscience. Mutant gene tied to poor serotonin production and depression. Science (New York, N.Y.). vol 306. issue 5704. 2005-01-14. PMID:15604378. |
mutant gene tied to poor serotonin production and depression. |
2005-01-14 |
2023-08-12 |
Not clear |
| J De Vry, R Schreiber, C Melon, M Dalmus, K R Jentzsc. 5-HT1A receptors are differentially involved in the anxiolytic- and antidepressant-like effects of 8-OH-DPAT and fluoxetine in the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14. issue 6. 2005-01-13. PMID:15589388. |
fluoxetine, a selective serotonin reuptake inhibitor, shows moderate efficacy and potency in the rat forced swimming depression test and the shock-induced ultrasonic vocalization anxiety test, whereas the 5-ht(1a) receptor agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) is highly efficient and potent in both models. |
2005-01-13 |
2023-08-12 |
rat |
| Mike Brile. Clinical experience with dual action antidepressants in different chronic pain syndromes. Human psychopharmacology. vol 19 Suppl 1. 2005-01-12. PMID:15378667. |
a common psychopharmacology between pain and depression suggests that compounds inhibiting the reuptake of serotonin and/or noradrenaline are likely to produce relief from chronic pain. |
2005-01-12 |
2023-08-12 |
Not clear |
| Demet Akin, D Hal Manier, Elaine Sanders-Bush, Richard C Shelto. Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 11. 2005-01-11. PMID:15187984. |
this study was intended to evaluate 5-ht(2a) receptor-coupled activation of phosphatidylinositol (pi) hydrolysis in subtypes of depression. |
2005-01-11 |
2023-08-12 |
Not clear |
| Thomas R Kosten, Therese A Koste. New medication strategies for comorbid substance use and bipolar affective disorders. Biological psychiatry. vol 56. issue 10. 2005-01-11. PMID:15556122. |
adding atypical antipsychotic agents might not improve valproate's efficacy, but combining gaba medications with selective serotonin reuptake inhibitors holds promise for sud with depression. |
2005-01-11 |
2023-08-12 |
Not clear |
| Masafumi Kodama, Takashi Fujioka, Ronald S Duma. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biological psychiatry. vol 56. issue 8. 2005-01-10. PMID:15476686. |
there has been increasing evidence that atypical antipsychotics are effective in the treatment of mood disorders or for augmenting 5-hydroxytryptamine selective reuptake inhibitors for treatment-resistant depression. |
2005-01-10 |
2023-08-12 |
rat |
| Nicole Praschak-Rieder, Douglas Hussey, Alan A Wilson, Anna Carella, Maggie Lee, Edward Dunn, Matthäus Willeit, R Michael Bagby, Sylvain Houle, Jeffrey H Meye. Tryptophan depletion and serotonin loss in selective serotonin reuptake inhibitor-treated depression: an [(18)F] MPPF positron emission tomography study. Biological psychiatry. vol 56. issue 8. 2005-01-10. PMID:15476688. |
tryptophan depletion and serotonin loss in selective serotonin reuptake inhibitor-treated depression: an [(18)f] mppf positron emission tomography study. |
2005-01-10 |
2023-08-12 |
Not clear |
| Nicole Praschak-Rieder, Douglas Hussey, Alan A Wilson, Anna Carella, Maggie Lee, Edward Dunn, Matthäus Willeit, R Michael Bagby, Sylvain Houle, Jeffrey H Meye. Tryptophan depletion and serotonin loss in selective serotonin reuptake inhibitor-treated depression: an [(18)F] MPPF positron emission tomography study. Biological psychiatry. vol 56. issue 8. 2005-01-10. PMID:15476688. |
recurrence of depressive symptoms after tryptophan depletion (td) in selective serotonin reuptake inhibitor (ssri)-treated depression is an important, unexplained phenomenon. |
2005-01-10 |
2023-08-12 |
Not clear |
| Nicole Praschak-Rieder, Douglas Hussey, Alan A Wilson, Anna Carella, Maggie Lee, Edward Dunn, Matthäus Willeit, R Michael Bagby, Sylvain Houle, Jeffrey H Meye. Tryptophan depletion and serotonin loss in selective serotonin reuptake inhibitor-treated depression: an [(18)F] MPPF positron emission tomography study. Biological psychiatry. vol 56. issue 8. 2005-01-10. PMID:15476688. |
with [(18)f] mppf positron emission tomography (pet), serotonin (5-hydroxytryptamine, 5-ht) 1a receptor binding potential (5-ht(1a)bp) was measured after td in various brain regions in citalopram-treated depression. |
2005-01-10 |
2023-08-12 |
Not clear |
| Alex Malinin, Benjamin Oshrine, Victor Serebruan. Treatment with selective serotonin reuptake inhibitors for enhancing wound healing. Medical hypotheses. vol 63. issue 1. 2005-01-06. PMID:15193359. |
selective serotonin reuptake inhibitors (ssris) are well-established medications for the treatment of mood disorders including major depression. |
2005-01-06 |
2023-08-12 |
Not clear |
| Tommi Tolmunen, Mikko Joensuu, Pirjo Irmeli Saarinen, Hanna Mussalo, Pasi Ahola, Ritva Vanninen, Jyrki Kuikka, Jari Tiihonen, Johannes Lehtone. Elevated midbrain serotonin transporter availability in mixed mania: a case report. BMC psychiatry. vol 4. 2004-12-30. PMID:15363105. |
results obtained from brain imaging studies indicate that serotonin transporter (sert) and dopamine transporter (dat) densities are altered in major depression. |
2004-12-30 |
2023-08-12 |
Not clear |
| H M van Praa. Can stress cause depression? Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 5. 2004-12-30. PMID:15363612. |
focussing on 5-hydroxytryptamine (5-ht) and the stress hormones, this question was answered in the affirmative, based on the following two considerations: changes in the 5-ht and stress hormone systems produced by sustained stress mimic to a substantial extent the disturbances in these systems that may be observed in depression. |
2004-12-30 |
2023-08-12 |
Not clear |
| H M van Praa. Can stress cause depression? Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 5. 2004-12-30. PMID:15363612. |
substantial evidence indicates that the 5-ht and stress hormone disturbances in depression are of pathophysiological significance and not merely a consequence of the depressed state or a product of stress generated by the depressed state. |
2004-12-30 |
2023-08-12 |
Not clear |
| Richard De La Garza, James J Mahone. A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: implications for animal models of anxiety and depression. Brain research. vol 1021. issue 2. 2004-12-23. PMID:15342269. |
the neurochemical results demonstrate distinct patterns of baseline and stress-induced monoamine turnover in wky rats, including alterations to da and 5-ht turnovers in prefrontal cortex and nucleus accumbens, two critical brain areas implicated in anxiety, depression and drug reward. |
2004-12-23 |
2023-08-12 |
rat |
| K M Smits, L J M Smits, J S A G Schouten, F F Stelma, P Nelemans, M H Prin. Influence of SERTPR and STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review. Molecular psychiatry. vol 9. issue 5. 2004-12-22. PMID:15037864. |
influence of sertpr and stin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review. |
2004-12-22 |
2023-08-12 |
Not clear |