| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nathan A Gillespie, John B Whitfield, Ben Williams, Andrew C Heath, Nicholas G Marti. The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression. Psychological medicine. vol 35. issue 1. 2005-05-17. PMID:15842033. |
we attempted to replicate the study by caspi and colleagues [science (2003) 301, 386-389] which reported a significant interaction between serotonin transporter (5-httlpr) genotype and stressful life events when predicting major depression. |
2005-05-17 |
2023-08-12 |
Not clear |
| P M Wehmeier, M Kluge, A Maras, D Riemann, M Berger, R Kohnen, R W Dittmann, W F Gatta. Fluoxetine versus trimipramine in the treatment of depression in geriatric patients. Pharmacopsychiatry. vol 38. issue 1. 2005-05-16. PMID:15706460. |
fluoxetine, a selective serotonin reuptake inhibitor (ssri), and trimipramine, a tricyclic antidepressant (tca), were compared in terms of efficacy and tolerability in a six-week, parallel group, double-blind pilot study in 41 geriatric patients with major depression (61 - 85 years old). |
2005-05-16 |
2023-08-12 |
Not clear |
| John J Worthington, Gustavo Kinrys, Lisa E Wygant, Mark H Pollac. Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients. International clinical psychopharmacology. vol 20. issue 1. 2005-05-10. PMID:15602109. |
aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients. |
2005-05-10 |
2023-08-12 |
human |
| John J Worthington, Gustavo Kinrys, Lisa E Wygant, Mark H Pollac. Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients. International clinical psychopharmacology. vol 20. issue 1. 2005-05-10. PMID:15602109. |
we report on patients with depression and anxiety disorders, including panic disorder, generalized anxiety disorder, social anxiety and post-traumatic stress disorder, who had an incomplete response to a variety of selective serotonin reuptake inhibitors (ssris) and who received augmentation with aripiprazole. |
2005-05-10 |
2023-08-12 |
human |
| Xiomara A Perez, Anne M Andrew. Chronoamperometry to determine differential reductions in uptake in brain synaptosomes from serotonin transporter knockout mice. Analytical chemistry. vol 77. issue 3. 2005-05-05. PMID:15679349. |
in humans, a commonly expressed genetic variant of the serotonin transporter gene results in 40% reductions in sert expression that have been linked to increases in anxiety-related personality traits and susceptibility to stress-associated depression. |
2005-05-05 |
2023-08-12 |
mouse |
| Tiffany Field, Miguel Diego, Maria Hernandez-Reif, Karla Gil, Yanexy Ver. Prenatal maternal cortisol, fetal activity and growth. The International journal of neuroscience. vol 115. issue 3. 2005-05-04. PMID:15825247. |
the women were given the ces-d for depression and the state-trait anxiety inventory and were asked to provide a urine sample to be assayed for cortisol, norepinephrine, epinephrine, dopamine, and serotonin. |
2005-05-04 |
2023-08-12 |
Not clear |
| Jean-Michel Le Mellédo, Jorge Pere. Selective serotonin reuptake inhibitors (SSRIs) and depression after myocardial infarction (MI). Journal of psychiatry & neuroscience : JPN. vol 30. issue 2. 2005-04-29. PMID:15798791. |
selective serotonin reuptake inhibitors (ssris) and depression after myocardial infarction (mi). |
2005-04-29 |
2023-08-12 |
Not clear |
| Motoko Honda, Keiko Imaida, Mitsuo Tanabe, Hideki On. Endogenously released 5-hydroxytryptamine depresses the spinal monosynaptic reflex via 5-HT1D receptors. European journal of pharmacology. vol 503. issue 1-3. 2005-04-25. PMID:15496296. |
previously, we have shown that 5-ht1b receptors mediate the monosynaptic reflex depression induced by exogenously applied 5-ht that was formed from the precursor l-5-hydroxytryptophan in spinalized rats. |
2005-04-25 |
2023-08-12 |
rat |
| Motoko Honda, Keiko Imaida, Mitsuo Tanabe, Hideki On. Endogenously released 5-hydroxytryptamine depresses the spinal monosynaptic reflex via 5-HT1D receptors. European journal of pharmacology. vol 503. issue 1-3. 2005-04-25. PMID:15496296. |
the depletion of 5-ht abolished the monosynaptic reflex depression, but the increase in polysynaptic reflexes was maintained, suggesting that endogenous 5-ht released by dl-p-chloroamphetamine mediates depression of the monosynaptic reflex in the spinal cord. |
2005-04-25 |
2023-08-12 |
rat |
| Motoko Honda, Keiko Imaida, Mitsuo Tanabe, Hideki On. Endogenously released 5-hydroxytryptamine depresses the spinal monosynaptic reflex via 5-HT1D receptors. European journal of pharmacology. vol 503. issue 1-3. 2005-04-25. PMID:15496296. |
the depression of the monosynaptic reflex was antagonized by gr127935 (n-[methoxy-3-(4-methyl-l-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1-biphenyl]-4-carboxamide; 5-ht1b/1d receptor antagonist) and brl15572 (3-[4-(4-chlorophenyl)piperazin-1-yl]-1,1-diphenyl-2-propanol; 5-ht1d receptor antagonist) but not by isamoltane (5-ht(1b) receptor antagonist). |
2005-04-25 |
2023-08-12 |
rat |
| Patricia L Haynes, John R McQuaid, John Kelsoe, Mark Rapaport, J Christian Gilli. Affective state and EEG sleep profile in response to rapid tryptophan depletion in recently recovered nonmedicated depressed individuals. Journal of affective disorders. vol 83. issue 2-3. 2005-04-22. PMID:15555723. |
tfd is thought to reduce cerebral serotonin, a neurotransmitter implicated in depression. |
2005-04-22 |
2023-08-12 |
Not clear |
| Maria Waselus, Rita J Valentino, Elisabeth J Van Bockstael. Ultrastructural evidence for a role of gamma-aminobutyric acid in mediating the effects of corticotropin-releasing factor on the rat dorsal raphe serotonin system. The Journal of comparative neurology. vol 482. issue 2. 2005-04-18. PMID:15611993. |
the dorsal raphe nucleus (drn) serotonin (5-ht) system has been implicated in acute responses to stress and in stress-related psychiatric disorders such as anxiety and depression. |
2005-04-18 |
2023-08-12 |
rat |
| Theodore B Henry, Jeong-Wook Kwon, Kevin L Armbrust, Marsha C Blac. Acute and chronic toxicity of five selective serotonin reuptake inhibitors in Ceriodaphnia dubia. Environmental toxicology and chemistry. vol 23. issue 9. 2005-04-14. PMID:15379001. |
selective serotonin reuptake inhibitors (ssris) are drugs used to treat clinical depression in humans, and have been detected in low concentrations in surface waters. |
2005-04-14 |
2023-08-12 |
Not clear |
| Martin B Keller, Frank J L Ruwe, Cecile J J G Janssens, J M Ad Sitsen, Riitta Jokinen, Janusz Janczewsk. Relapse prevention with gepirone ER in outpatients with major depression. Journal of clinical psychopharmacology. vol 25. issue 1. 2005-04-08. PMID:15643103. |
to evaluate long-term efficacy and tolerability of the serotonin 5-ht1a receptor agonist, gepirone extended release (er), a multicenter, randomized, placebo-controlled relapse prevention study was performed in patients with recurrent major depression (dsm-iv criteria). |
2005-04-08 |
2023-08-12 |
Not clear |
| Matthias R Lemke, Gerd Fuchs, Irene Gemende, Birgit Herting, Christian Oehlwein, Heinz Reichmann, Jürgen Rieke, Jens Volkman. Depression and Parkinson's disease. Journal of neurology. vol 251 Suppl 6. 2005-04-08. PMID:15675721. |
tricyclic and newer, selective antidepressants including serotonin and noradrenaline reuptake inhibitors (ssri, snri) appear to be effective in treating depression in pd. |
2005-04-08 |
2023-08-12 |
Not clear |
| David J Nut. Overview of diagnosis and drug treatments of anxiety disorders. CNS spectrums. vol 10. issue 1. 2005-04-07. PMID:15618947. |
the common co-existence of depression with all of the anxiety disorders means that the selective serotonin reuptake inhibitors are now generally considered to be the first-line treatments but the benzodiazepines have some utility especially in promoting sleep and working acutely to reduce extreme distress. |
2005-04-07 |
2023-08-12 |
Not clear |
| Jack M Gorman, Andrew Korotzer, Guojin S. Efficacy comparison of escitalopram and citalopram in the treatment of major depressive disorder: pooled analysis of placebo-controlled trials. CNS spectrums. vol 7. issue 4 Suppl 1. 2005-04-04. PMID:15131492. |
citalopram is a racemic selective serotonin reuptake inhibitor (ssri) indicated for the treatment of depression. |
2005-04-04 |
2023-08-12 |
Not clear |
| Jack M Gorman, Andrew Korotzer, Guojin S. Efficacy comparison of escitalopram and citalopram in the treatment of major depressive disorder: pooled analysis of placebo-controlled trials. CNS spectrums. vol 7. issue 4 Suppl 1. 2005-04-04. PMID:15131492. |
citalopram is a racemate and its serotonin reuptake inhibitory activity resides primarily in the single s-isomer, escitalopram, which is now being evaluated for its potential usefulness in the treatment of depression and other psychiatric disorders. |
2005-04-04 |
2023-08-12 |
Not clear |
| Orli Kampf-Sherf, Zoli Zlotogorski, Asaf Gilboa, Lynn Speedie, Jossef Lereya, Paula Rosca, Yehuda Shavi. Neuropsychological functioning in major depression and responsiveness to selective serotonin reuptake inhibitors antidepressants. Journal of affective disorders. vol 82. issue 3. 2005-04-04. PMID:15555698. |
neuropsychological functioning in major depression and responsiveness to selective serotonin reuptake inhibitors antidepressants. |
2005-04-04 |
2023-08-12 |
Not clear |
| Rebecca A Richell, J F William Deakin, Ian M Anderso. Effect of acute tryptophan depletion on the response to controllable and uncontrollable noise stress. Biological psychiatry. vol 57. issue 3. 2005-04-01. PMID:15691531. |
previous research provides evidence linking serotonin (5-hydroxytryptamine, 5-ht) with stress and depression. |
2005-04-01 |
2023-08-12 |
Not clear |