| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Anttila, E-L Helkala, M Kivipelto, M Hallikainen, K Alhainen, H Heinonen, A Mannermaa, J Tuomilehto, H Soininen, A Nissine. Midlife income, occupation, APOE status, and dementia: a population-based study. Neurology. vol 59. issue 6. 2002-10-16. PMID:12297572. |
to examine the relationship between socioeconomic factors and apoe carrier status on the development of dementia. |
2002-10-16 |
2023-08-12 |
Not clear |
| Abbas Parsian, Brad Racette, L Jane Goldsmith, Joel S Perlmutte. Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset. Genomics. vol 79. issue 3. 2002-06-04. PMID:11863377. |
apolipoprotein e (apoe) allele epsilon4 has been associated with familial and sporadic late-onset senile dementia of the alzheimer's type. |
2002-06-04 |
2023-08-12 |
Not clear |
| Abbas Parsian, Brad Racette, L Jane Goldsmith, Joel S Perlmutte. Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset. Genomics. vol 79. issue 3. 2002-06-04. PMID:11863377. |
to investigate the role of this gene in the development of dementia associated with pd and age at onset of pd, we evaluated the frequency of apoe gene polymorphism in a sample of pd patients with (n=118) and without (n=167) a family history, as well as matched normal controls (n=96). |
2002-06-04 |
2023-08-12 |
Not clear |
| Abbas Parsian, Brad Racette, L Jane Goldsmith, Joel S Perlmutte. Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset. Genomics. vol 79. issue 3. 2002-06-04. PMID:11863377. |
we conclude that apoe does not play an important role in susceptibility to pd or age at onset of pd, but may play a role in dementia associated with pd in our sample. |
2002-06-04 |
2023-08-12 |
Not clear |
| M Riemenschneider, J Diehl, U Müller, H Förstl, A Kur. Apolipoprotein E polymorphism in German patients with frontotemporal degeneration. Journal of neurology, neurosurgery, and psychiatry. vol 72. issue 5. 2002-05-22. PMID:11971052. |
the apolipoprotein e (apoe) polymorphism, designated as epsilon2, epsilon3, epsilon4, is a genetic risk factor associated with several forms of dementia. |
2002-05-22 |
2023-08-12 |
Not clear |
| Rita Peila, Beatriz L Rodriguez, Lenore J Laune. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes. vol 51. issue 4. 2002-05-10. PMID:11916953. |
type 2 diabetes, apoe gene, and the risk for dementia and related pathologies: the honolulu-asia aging study. |
2002-05-10 |
2023-08-12 |
human |
| Rita Peila, Beatriz L Rodriguez, Lenore J Laune. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes. vol 51. issue 4. 2002-05-10. PMID:11916953. |
we evaluated the association of diabetes alone or combined with the apolipoprotein e (apoe) gene with incident dementia and neuropathological outcomes in a population-based cohort of 2,574 japanese-american men enrolled in the honolulu-asia aging study, including 216 subjects who underwent autopsy. |
2002-05-10 |
2023-08-12 |
human |
| Henry Brodaty, Philip Mitchell, Georgina Luscombe, John J Kwok, Renee F Badenhop, Rod McKenzie, Peter R Schofiel. Familial idiopathic basal ganglia calcification (Fahr's disease) without neurological, cognitive and psychiatric symptoms is not linked to the IBGC1 locus on chromosome 14q. Human genetics. vol 110. issue 1. 2002-05-09. PMID:11810290. |
we genotyped all family members for microsatellite markers at the ibgc1 locus and polymorphisms of the apoe, vldl, alpha1-act, bche-k, app, ps1, ps2 and tau genes and tested these for linkage to ibgc, dementia and bipolar disorder. |
2002-05-09 |
2023-08-12 |
Not clear |
| Henry Brodaty, Philip Mitchell, Georgina Luscombe, John J Kwok, Renee F Badenhop, Rod McKenzie, Peter R Schofiel. Familial idiopathic basal ganglia calcification (Fahr's disease) without neurological, cognitive and psychiatric symptoms is not linked to the IBGC1 locus on chromosome 14q. Human genetics. vol 110. issue 1. 2002-05-09. PMID:11810290. |
of the eight dementia gene markers tested, the only positive lod score was for the apoe epsilon4 polymorphism and dementia/severe cognitive impairment. |
2002-05-09 |
2023-08-12 |
Not clear |
| M D Benedetti, A Salviati, S Filipponi, M Manfredi, L De Togni, M Gomez Lira, G Stenta, E Fincati, M Pampanin, N Rizzuto, G Dant. Prevalence of dementia and apolipoprotein e genotype distribution in the elderly of buttapietra, verona province, Italy. Neuroepidemiology. vol 21. issue 2. 2002-05-07. PMID:11901276. |
we investigated the prevalence of dementia and the apolipoprotein e (apoe) genotype distribution in the elderly of buttapietra, a village near verona, italy. |
2002-05-07 |
2023-08-12 |
Not clear |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
polymorphisms within the genes encoding apolipoprotein e (apoe), apolipoprotein ci (apoci), alpha1-antichymotrypsin (act), the low-density lipoprotein (ldl) receptor and lipoprotein lipase were investigated in patients suffering from alzheimer's dementia and non-demented psychiatric patients as control subjects. |
2002-05-02 |
2023-08-12 |
human |
| Z Janka, A Juhász, A Rimanóczy A, K Boda, J Márki-Zay, J Kálmá. Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias. Molecular psychiatry. vol 7. issue 1. 2002-04-19. PMID:11803456. |
(3-8) the importance of cardiovascular risk factors in the pathomechanism of alzheimer's disease (ad) and vascular dementia (vd)(9-13) prompted us to examine the genetic effect of pon2 gene codon 311 (cys-->ser; pon2*s) polymorphism and the relationship between the pon2*s allele and the other dementia risk factor, the apoe polymorphism in these dementias. |
2002-04-19 |
2023-08-12 |
Not clear |
| M Riemenschneider, M Schmolke, N Lautenschlager, H Vanderstichele, E Vanmechelen, W G Guder, A Kur. Association of CSF apolipoprotein E, Abeta42 and cognition in Alzheimer's disease. Neurobiology of aging. vol 23. issue 2. 2002-02-28. PMID:11804704. |
in this study we extended our observations on apoe, as another plaque component, and investigated the association between csf apoe concentrations and cognitive performance after stratification for the apoe genotype in 62 patients with ad, 19 other forms of dementia and 18 controls. |
2002-02-28 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
association of apoe epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. |
2002-02-12 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
the common apolipoprotein e (apoe) alleles epsilon2, epsilon3, and epsilon4 are associated with the risk of dementia and cardiovascular disease. |
2002-02-12 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
we investigated the contribution of these apoe gene variants to dementia and cardiovascular mortality in old age using a population-based cohort of 648 subjects aged 85 years and over (leiden 85-plus study). |
2002-02-12 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
genotypes containing an apoe epsilon4 allele were associated with a 4.1-fold (95% ci, 2.2-7.7) increased risk of dementia as compared to the epsilon3/epsilon3 genotype in old subjects. |
2002-02-12 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
in conclusion, both the apoe epsilon2/epsilon3/epsilon4 and the -219g/t variant were identified as risk factors for dementia but not cardiovascular mortality in old age. |
2002-02-12 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
our results support the hypothesis that both the isoform and the amount of apoe may influence the risk of dementia. |
2002-02-12 |
2023-08-12 |
human |
| Bastiaan T Heijmans, P Eline Slagboom, Jacobijn Gussekloo, Simone Droog, A Margot Lagaay, Cornelis Kluft, Dick L Knook, Rudi G J Westendor. Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. American journal of medical genetics. vol 107. issue 3. 2002-02-12. PMID:11807900. |
furthermore, they emphasize that variation at the apoe locus has a higher impact on the risk of dementia than on the risk of cardiovascular disease in old age. |
2002-02-12 |
2023-08-12 |
human |