| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hsiu-Fen Lin, Chiou-Lian Lai, Chih-Ta Tai, Ruey-Tay Lin, Ching-Kuan Li. Apolipoprotein E polymorphism in ischemic cerebrovascular diseases and vascular dementia patients in Taiwan. Neuroepidemiology. vol 23. issue 3. 2004-08-26. PMID:15084782. |
this study aims to clarify the association between apolipoprotein e gene (apoe) polymorphism, ischemic cerebrovascular diseases (icvd) and vascular dementia (vad) in taiwan chinese. |
2004-08-26 |
2023-08-12 |
Not clear |
| John F Ervin, Catherine Pannell, Mari Szymanski, Kathleen Welsh-Bohmer, Donald E Schmechel, Christine M Hulett. Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis. Journal of neuropathology and experimental neurology. vol 63. issue 7. 2004-08-26. PMID:15290898. |
we analyzed smooth muscle actin (sma) immunoreactivity in brain blood vessels of 10 apoe 4,4 alzheimer disease (ad) patients and 10 apoe 3,3 ad patients matched for age, sex, and duration of dementia. |
2004-08-26 |
2023-08-12 |
Not clear |
| R F Itzhaki, C B Dobson, S J Shipley, M A Woznia. The role of viruses and of APOE in dementia. Annals of the New York Academy of Sciences. vol 1019. 2004-08-20. PMID:15246985. |
the role of viruses and of apoe in dementia. |
2004-08-20 |
2023-08-12 |
Not clear |
| J Klages, J D Fis. The relation between APOE status and neuropsychological memory test performance: an analysis of the Canadian Study of Health and Aging. Brain and cognition. vol 49. issue 2. 2004-08-19. PMID:15259389. |
while the apoe epsilon4 allele was associated with slightly lower memory test performance for persons without cognitive impairment at baseline, it only increased their risk of developing dementia if their memory was below average. |
2004-08-19 |
2023-08-12 |
human |
| J Cervilla, M Prince, S Joels, S Lovestone, A Man. Premorbid cognitive testing predicts the onset of dementia and Alzheimer's disease better than and independently of APOE genotype. Journal of neurology, neurosurgery, and psychiatry. vol 75. issue 8. 2004-08-18. PMID:15258208. |
premorbid cognitive testing predicts the onset of dementia and alzheimer's disease better than and independently of apoe genotype. |
2004-08-18 |
2023-08-12 |
Not clear |
| J Cervilla, M Prince, S Joels, S Lovestone, A Man. Premorbid cognitive testing predicts the onset of dementia and Alzheimer's disease better than and independently of APOE genotype. Journal of neurology, neurosurgery, and psychiatry. vol 75. issue 8. 2004-08-18. PMID:15258208. |
to determine whether a cognitive test package can predict the onset of dementia up to 11 years later, and the extent to which this prediction is independent of that provided by apoe genotype. |
2004-08-18 |
2023-08-12 |
Not clear |
| Jean-Charles Lambert, Claudine Berr, Dominique Cottel, Philippe Amouyel, Nicole Helbecqu. APOE promoter polymorphisms and dementia in the elderly. Neuroscience letters. vol 365. issue 2. 2004-08-09. PMID:15245790. |
apoe promoter polymorphisms and dementia in the elderly. |
2004-08-09 |
2023-08-12 |
human |
| Jean-Charles Lambert, Claudine Berr, Dominique Cottel, Philippe Amouyel, Nicole Helbecqu. APOE promoter polymorphisms and dementia in the elderly. Neuroscience letters. vol 365. issue 2. 2004-08-09. PMID:15245790. |
previous observations suggest a contribution of two apoe promoter polymorphisms (-219 g/t and -491 a/t) in dementia. |
2004-08-09 |
2023-08-12 |
human |
| Jean-Charles Lambert, Claudine Berr, Dominique Cottel, Philippe Amouyel, Nicole Helbecqu. APOE promoter polymorphisms and dementia in the elderly. Neuroscience letters. vol 365. issue 2. 2004-08-09. PMID:15245790. |
haplotype estimations including the two promoter and the coding apoe polymorphisms indicated that the -491a/-219t/4 haplotype was at risk for the development of dementia (or = 3.5 (95% ci, 2.5-5.0), p < 0.0001), whereas the -491a/-219g/4 haplotype was not (or = 1.1 (95% ci, 0.6-2.1)). |
2004-08-09 |
2023-08-12 |
human |
| A J C Slooter, M Cruts, A Hofman, P J Koudstaal, D van der Kuip, M A J de Ridder, J C M Witteman, M M B Breteler, C Van Broeckhoven, C M van Duij. The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study. Neurology. vol 62. issue 7. 2004-08-02. PMID:15079025. |
the impact of apoe on myocardial infarction, stroke, and dementia: the rotterdam study. |
2004-08-02 |
2023-08-12 |
Not clear |
| A J C Slooter, M Cruts, A Hofman, P J Koudstaal, D van der Kuip, M A J de Ridder, J C M Witteman, M M B Breteler, C Van Broeckhoven, C M van Duij. The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study. Neurology. vol 62. issue 7. 2004-08-02. PMID:15079025. |
it is unclear how the apoe genotype contributes to the incidence of vascular diseases and dementia. |
2004-08-02 |
2023-08-12 |
Not clear |
| A J C Slooter, M Cruts, A Hofman, P J Koudstaal, D van der Kuip, M A J de Ridder, J C M Witteman, M M B Breteler, C Van Broeckhoven, C M van Duij. The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study. Neurology. vol 62. issue 7. 2004-08-02. PMID:15079025. |
apoe is not strongly related to vascular diseases, but contributes substantially to dementia incidence. |
2004-08-02 |
2023-08-12 |
Not clear |
| Frank-Erik de Leeuw, Florence Richard, Jan Cees de Groot, Cornelia M van Duijn, Albert Hofman, Jan Van Gijn, Monique M B Bretele. Interaction between hypertension, apoE, and cerebral white matter lesions. Stroke. vol 35. issue 5. 2004-05-19. PMID:15060316. |
the epsilon4 allele of the apolipoprotein e gene (apoe) may be a candidate because this allele is associated with both the vascular risk factors and the consequences (cognitive impairment, dementia) of wmls. |
2004-05-19 |
2023-08-12 |
Not clear |
| M Boccardi, F Sabattoli, C Testa, A Beltramello, H Soininen, G B Frison. APOE and modulation of Alzheimer's and frontotemporal dementia. Neuroscience letters. vol 356. issue 3. 2004-05-10. PMID:15036621. |
the epsilon4 allele of the apoe might modulate the expression of degenerative dementias by enhancing the specific effects of neurodegenerative diseases on the brain. |
2004-05-10 |
2023-08-12 |
Not clear |
| Kalpana Luthra, Manjari Tripathi, Rahul Grover, Manjari Dwivedi, Amit Kumar, A B De. Apolipoprotein E gene polymorphism in Indian patients with Alzheimer's disease and vascular dementia. Dementia and geriatric cognitive disorders. vol 17. issue 3. 2004-05-03. PMID:14739533. |
however, the association of apoe polymorphism with vascular dementia (vad) is yet to be established in this population. |
2004-05-03 |
2023-08-12 |
Not clear |
| Deng Chen, Jun-Wu Zhang, Zhen-Xin Zhang, Hua-Lu Zhao, Xiao-Qing Li, Ya-Ning Wu, Qiu-Ming Q. [Apolipoprotein E gene polymorphisms and Alzheimer disease]. Yi chuan xue bao = Acta genetica Sinica. vol 30. issue 12. 2004-04-22. PMID:14986436. |
in addition, our results showed that the distributions of apoe alleles and genotypes were comparable among mild, moderate and severe dementia patients (p > 0.05), suggesting that apoe gene polymorphism was not likely to contribute to dementia severity of ad patients. |
2004-04-22 |
2023-08-12 |
human |
| Bogusław Paradowski, Tadeusz Dobosz, Maria Sasiadek, Małgorzata Szczepania. [Apolipoprotein E and tau protein in vascular dementia]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 15. issue 85. 2004-03-08. PMID:14593964. |
in 33 patients meeting the ninds-airen criteria of possible diagnosis of vascular dementia (vd) apoe genotype and tau protein level in cerebrospinal fluid were determined. |
2004-03-08 |
2023-08-12 |
Not clear |
| Bogusław Paradowski, Tadeusz Dobosz, Maria Sasiadek, Małgorzata Szczepania. [Apolipoprotein E and tau protein in vascular dementia]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 15. issue 85. 2004-03-08. PMID:14593964. |
the authors emphasize that apoe e4 and tau protein level determination is not very useful in the differential diagnosis of dementia. |
2004-03-08 |
2023-08-12 |
Not clear |
| Y Ji, Y Gong, W Gan, T Beach, D M Holtzman, T Wisniewsk. Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients. Neuroscience. vol 122. issue 2. 2004-03-01. PMID:14614898. |
these age dependent differences in the effects of apoe isoforms on neuronal integrity may relate to the increased risk of dementia in aged individuals with the apoe4 allele. |
2004-03-01 |
2023-08-12 |
mouse |
| Kathleen A Lane, Sujuan Gao, Siu L Hui, Jill R Murrell, Kathleen S Hall, Hugh C Hendri. Apolipoprotein E and mortality in African-Americans and Yoruba. Journal of Alzheimer's disease : JAD. vol 5. issue 5. 2004-02-24. PMID:14646029. |
we used data from the indianapolis-ibadan dementia study to examine this association between apoe and mortality in 354 african-americans from indianapolis and 968 yoruba from ibadan, nigeria. |
2004-02-24 |
2023-08-12 |
human |