| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer D Klages, John D Fisk, Kenneth Rockwoo. APOE genotype, vascular risk factors, memory test performance and the five-year risk of vascular cognitive impairment or Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 20. issue 5. 2005-12-01. PMID:16166776. |
the apoe epsilon4 gene and poor memory test performance have each been associated with an increased risk of developing dementia, but the relationship between these risk factors in predicting dementia is unclear. |
2005-12-01 |
2023-08-12 |
Not clear |
| Spencer R Wetter, Dean C Delis, Wes S Houston, Mark W Jacobson, Amy Lansing, Krystal Cobell, David P Salmon, Mark W Bond. Deficits in inhibition and flexibility are associated with the APOE-E4 allele in nondemented older adults. Journal of clinical and experimental neuropsychology. vol 27. issue 8. 2005-11-30. PMID:16207619. |
this prospective study of nondemented older adults at genetic risk for ad and other types of dementia (i.e., apoe e4 allele) utilized a new stroop test that includes a dual executive-function condition requiring both response inhibition and cognitive switching. |
2005-11-30 |
2023-08-12 |
human |
| Chengxuan Qiu, Laura Fratiglion. Epidemiology of cerebrovascular disease related cognitive decline. International psychogeriatrics. vol 15 Suppl 1. 2005-11-15. PMID:16191225. |
cerebrovascluar disease may lead to cognitive decline and promote the clinical expression of dementia directly or by interaction with apoe epsilon4. |
2005-11-15 |
2023-08-12 |
Not clear |
| Anna Juhász, András Palotás, Zoltán Janka, Agnes Rimanóczy, Miklós Palotás, Nikoletta Bódi, Krisztina Boda, Marianna Zana, Gábor Vincze, János Kálmá. ApoE -491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population. Neurochemical research. vol 30. issue 5. 2005-10-31. PMID:16176061. |
apoe -491a/t promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in hungarian alzheimer's dementia population. |
2005-10-31 |
2023-08-12 |
Not clear |
| Rose Calhoun-Haney, Claire Murph. Apolipoprotein epsilon4 is associated with more rapid decline in odor identification than in odor threshold or Dementia Rating Scale scores. Brain and cognition. vol 58. issue 2. 2005-09-15. PMID:15919549. |
these results suggest that declines in odor identification occur before declines in other measures of dementia in persons at risk for ad because of their apoe allele genetic status. |
2005-09-15 |
2023-08-12 |
human |
| L Mosconi, D Perani, S Sorbi, K Herholz, B Nacmias, V Holthoff, E Salmon, J-C Baron, M T R De Cristofaro, A Padovani, B Borroni, M Franceschi, L Bracco, A Pup. MCI conversion to dementia and the APOE genotype: a prediction study with FDG-PET. Neurology. vol 63. issue 12. 2005-08-15. PMID:15623696. |
mci conversion to dementia and the apoe genotype: a prediction study with fdg-pet. |
2005-08-15 |
2023-08-12 |
Not clear |
| Eric M Reiman, Kewei Chen, Gene E Alexander, Richard J Caselli, Daniel Bandy, David Osborne, Ann M Saunders, John Hard. Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 23. 2005-07-27. PMID:15932949. |
apolipoprotein e (apoe) epsilon4 gene dose (i.e., the number of epsilon4 alleles in a person's apoe genotype) is associated with a higher risk of ad and a younger age at dementia onset. |
2005-07-27 |
2023-08-12 |
human |
| Eric M Reiman, Kewei Chen, Gene E Alexander, Richard J Caselli, Daniel Bandy, David Osborne, Ann M Saunders, John Hard. Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 23. 2005-07-27. PMID:15932949. |
we previously found that cognitively normal late-middle-aged apoe epsilon4 carriers have abnormally low cmrgl in the same brain regions as patients with probable alzheimer's dementia. |
2005-07-27 |
2023-08-12 |
human |
| Adriano Jimenez-Escrig, Estrella Gomez-Tortosa, Manuel Baron, Alberto Rabano, Mauricio Arcos-Burgos, Luis Guillermo Palacios, Antonio Yusta, Pilar Anta, Immaculada Perez, Margarita Hierro, David G Munoz, Sagrario Barquer. A multigenerational pedigree of late-onset Alzheimer's disease implies new genetic causes. Brain : a journal of neurology. vol 128. issue Pt 7. 2005-07-18. PMID:15843424. |
seven out of 12 cases were apolipoprotein e (apoe) epsilon3/3, although the presence of an apoe epsilon4 allele was associated with an increased risk of dementia (odd ratio 6.17; 95% confidence interval: 1.15-33.15), but not to an earlier age of onset. |
2005-07-18 |
2023-08-12 |
human |
| A E Ashley-Koch, Y Shao, J B Rimmler, P C Gaskell, K A Welsh-Bohmer, C E Jackson, W K Scott, J L Haines, M A Pericak-Vanc. An autosomal genomic screen for dementia in an extended Amish family. Neuroscience letters. vol 379. issue 3. 2005-06-24. PMID:15843063. |
these data suggested that a genetic etiology independent of apoe may underlie the dementia observed in this population. |
2005-06-24 |
2023-08-12 |
Not clear |
| Timo E Strandberg, Kaisu Pitkala, Johanna Eerola, Reijo Tilvis, Pentti J Tienar. Interaction of herpesviridae, APOE gene, and education in cognitive impairment. Neurobiology of aging. vol 26. issue 7. 2005-05-20. PMID:15748778. |
these results demonstrate an interaction of specific genetic (apoe) and environmental (education and herpesviridae) risk factors in the development of cognitive impairment and indicate that not only the epsilon4 allele of apoe but also the epsilon3 haplotype is a risk factor for dementia. |
2005-05-20 |
2023-08-12 |
Not clear |
| Laura Jean Podewils, Eliseo Guallar, Lewis H Kuller, Linda P Fried, Oscar L Lopez, Michelle Carlson, Constantine G Lyketso. Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. American journal of epidemiology. vol 161. issue 7. 2005-05-12. PMID:15781953. |
physical activity, apoe genotype, and dementia risk: findings from the cardiovascular health cognition study. |
2005-05-12 |
2023-08-12 |
human |
| A F Jorm, P Butterworth, K J Anstey, H Christensen, S Easteal, J Maller, K A Mather, R I Turakulov, W Wen, P Sachde. Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities. Psychological medicine. vol 34. issue 8. 2005-04-19. PMID:15724880. |
the present study examined a range of possible determinants of memory complaints, covering psychiatric and personality factors, medical history, cognitive test performance, and biological risk factors for dementia (apoe genotype, hippocampus and amygdala volumes, and white-matter hyperintensities). |
2005-04-19 |
2023-08-12 |
Not clear |
| H Luukinen, P Viramo, M Herala, K Kervinen, Y A Kesäniemi, O Savola, S Winqvist, J Jokelainen, M Hillbo. Fall-related brain injuries and the risk of dementia in elderly people: a population-based study. European journal of neurology. vol 12. issue 2. 2005-03-16. PMID:15679695. |
in a population scoring > or =28 points in the baseline mmse an apolipoprotein e (apoe) epsilon4 phenotype was also associated with younger age at the time of detecting dementia; 3.56 (1.35-9.34), and the effect of brain injury and apoe epsilon4 phenotype was synergistic; 7.68 (2.32-25.3). |
2005-03-16 |
2023-08-12 |
human |
| H Luukinen, P Viramo, M Herala, K Kervinen, Y A Kesäniemi, O Savola, S Winqvist, J Jokelainen, M Hillbo. Fall-related brain injuries and the risk of dementia in elderly people: a population-based study. European journal of neurology. vol 12. issue 2. 2005-03-16. PMID:15679695. |
we conclude that fall-related tbi predicts earlier onset of dementia and the effect is especially high amongst subjects who carry the apoe epsilon4 allele. |
2005-03-16 |
2023-08-12 |
human |
| János Kálmán, Anna Juhász, Agnes Rimanóczy, András Palotás, Miklós Palotás, Krisztina Boda, János Márki-Zay, Eva Csibri, Zoltán Jank. The nitric oxide synthase-3 codon 298 polymorphism is not associated with late-onset sporadic Alzheimer's dementia and Lewy body disease in a sample from Hungary. Psychiatric genetics. vol 13. issue 4. 2005-01-11. PMID:14639046. |
an association study was performed between apolipoprotein e (apoe) polymorphism and the common structural polymorphism glu/asp at codon 298 of the nitric oxide synthase (nos3) gene in late-onset sporadic alzheimer's dementia probands (load), diffuse lewy body dementia cases (dlbd) and controls in a hungarian sample. |
2005-01-11 |
2023-08-12 |
Not clear |
| János Kálmán, Anna Juhász, Agnes Rimanóczy, András Palotás, Miklós Palotás, Krisztina Boda, János Márki-Zay, Eva Csibri, Zoltán Jank. The nitric oxide synthase-3 codon 298 polymorphism is not associated with late-onset sporadic Alzheimer's dementia and Lewy body disease in a sample from Hungary. Psychiatric genetics. vol 13. issue 4. 2005-01-11. PMID:14639046. |
the frequency of individuals who carried the apoe epsilon4 allele was significantly more common in both dementia groups (load, 20%; dlbd, 27%; control, 8%; control versus dlbd, chi2=13.264, degrees of freedom=2, p<0.001; control versus load, chi2=6.628, degrees of freedom=2, p<0.036). |
2005-01-11 |
2023-08-12 |
Not clear |
| L Flicker, R N Martins, J Thomas, J Acres, K Taddei, P Norman, K Jamrozik, O P Almeid. Homocysteine, Alzheimer genes and proteins, and measures of cognition and depression in older men. Journal of Alzheimer's disease : JAD. vol 6. issue 3. 2004-10-07. PMID:15201487. |
the epsilon4 allele of apolipoprotein e (apoe), and the plasma levels of apoe, amyloid beta-protein precursor, amyloid beta1-40 (abeta40) and homocysteine (hcy) have all been correlated with the presence of dementia. |
2004-10-07 |
2023-08-12 |
Not clear |
| Chava B Pocernich, Rukhsana Sultana, Eugene Hone, Jadwiga Turchan, Ralph N Martins, Vittorio Calabrese, Avindra Nath, D Allan Butterfiel. Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes. Journal of neuroscience research. vol 77. issue 4. 2004-10-04. PMID:15264223. |
the epsilon4 allele of the apolipoprotein e (apoe) gene currently is thought to play a role as a risk factor for the development of hiv dementia. |
2004-10-04 |
2023-08-12 |
mouse |
| M Rosich-Estragó, L Figuera-Terré, B Mulet-Pérez, M T Arrufat-Cardús, A Pascual San Emeterio, I Arbeola-Rigau, A Labad-Alquézar, E Vilella-Cuadrad. [Dementia and cognitive impairment pattern: its association with epsilon4 allele of apolipoprotein E gene]. Revista de neurologia. vol 38. issue 9. 2004-09-24. PMID:15152345. |
this disease is characterized by a typical progressive cognitive impairment pattern, different from that of other primary dementias such as dementia with lewy bodies or frontotemporal and vascular dementias, for which there are no conclusive results on the influence of the apoe genotype. |
2004-09-24 |
2023-08-12 |
Not clear |