| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L H Kulle. [Risk factors for dementia in the Cardiovascular Health Study cognition study]. Revista de neurologia. vol 37. issue 2. 2003-10-29. PMID:12938070. |
the chs found that age, modified mini mental state examination scores, cerebral ventricular size, severity of white matter lesions, number of mri identified infarcts, and the presence of the apoe 4 allele were predictors of dementia. |
2003-10-29 |
2023-08-12 |
human |
| L H Kulle. [Risk factors for dementia in the Cardiovascular Health Study cognition study]. Revista de neurologia. vol 37. issue 2. 2003-10-29. PMID:12938070. |
scores of global cognitive measures, the presence of the apoe 4 allele, and mri of the brain were strong predictors of dementia and ad. |
2003-10-29 |
2023-08-12 |
human |
| Michael J Finton, John A Lucas, Julie D Rippeth, Daryl L Bohac, Glenn E Smith, Robert J Ivnik, Ronald C Petersen, Neill R Graff-Radfor. Cognitive asymmetries associated with apolipoprotein E genotype in patients with Alzheimer's disease. Journal of the International Neuropsychological Society : JINS. vol 9. issue 5. 2003-09-23. PMID:12901781. |
although age and dementia severity also contributed to these patterns, apoe genotype appears to have a significant unique contribution to cognitive performance in these individuals. |
2003-09-23 |
2023-08-12 |
human |
| Annette Skraep Nielsen, Rivka Ravid, Wouter Kamphorst, Ole Steen Jørgense. Apolipoprotein E epsilon 4 in an autopsy series of various dementing disorders. Journal of Alzheimer's disease : JAD. vol 5. issue 2. 2003-09-16. PMID:12719629. |
previous studies on apoe epsilon 4 in dementing disorders other than ad have been rather conflicting, in particular concerning frontotemporal dementia (ftd) and vascular dementia (vd). |
2003-09-16 |
2023-08-12 |
human |
| S Engelborghs, B Dermaut, J Goeman, J Saerens, P Mariën, B A Pickut, M Van den Broeck, S Serneels, M Cruts, C Van Broeckhoven, P P De Dey. Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects. Journal of neurology, neurosurgery, and psychiatry. vol 74. issue 8. 2003-09-09. PMID:12876259. |
prospective belgian study of neurodegenerative and vascular dementia: apoe genotype effects. |
2003-09-09 |
2023-08-12 |
Not clear |
| J M Serra-Grabulosa, P Salgado-Pineda, C Junqué, C Solé-Padullés, P Moral, A López-Alomar, T López, A López-Guillén, N Bargalló, J M Mercader, I C Clemente, D Bartrés-Fa. Apolipoproteins E and C1 and brain morphology in memory impaired elders. Neurogenetics. vol 4. issue 3. 2003-08-01. PMID:12736801. |
previous research has shown that polymorphisms of the apolipoproteins e ( apoe) and apoc1 represent genetic risk factors for dementia and for cognitive impairment in the elderly. |
2003-08-01 |
2023-08-12 |
human |
| Yoon-Ho Choi, Ji-Hae Kim, Doh Kwan Kim, Jong-Won Kim, Duk-Kyung Kim, Mee Sook Lee, Cheol Ho Kim, Sang Chul Par. Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 58. issue 3. 2003-04-01. PMID:12634288. |
distributions of ace and apoe polymorphisms and their relations with dementia status in korean centenarians. |
2003-04-01 |
2023-08-12 |
human |
| Yoon-Ho Choi, Ji-Hae Kim, Doh Kwan Kim, Jong-Won Kim, Duk-Kyung Kim, Mee Sook Lee, Cheol Ho Kim, Sang Chul Par. Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 58. issue 3. 2003-04-01. PMID:12634288. |
genetic polymorphisms of angiotensin-converting enzyme (ace) and apolipoprotein e (apoe) have been reported to be associated with human longevity and dementia in the elderly. |
2003-04-01 |
2023-08-12 |
human |
| Paola Castelli, Ana Luisa Sosa, Carlos Campillo, Humberto Nicolini, Carlos Cruz-Fuente. Apolipoprotein E genotypes in a group of elderly subjects of Spanish descent living in Mexico City. International psychogeriatrics. vol 14. issue 3. 2003-03-26. PMID:12475089. |
the association between the apoe gene and alzheimer's disease and other forms of dementia has been widely documented, but its relevance as a genetic risk factor in specific ethnic groups other than caucasians in the united states and europe is limited. |
2003-03-26 |
2023-08-12 |
human |
| Paola Castelli, Ana Luisa Sosa, Carlos Campillo, Humberto Nicolini, Carlos Cruz-Fuente. Apolipoprotein E genotypes in a group of elderly subjects of Spanish descent living in Mexico City. International psychogeriatrics. vol 14. issue 3. 2003-03-26. PMID:12475089. |
the higher frequency of the epsilon4 allele in the affected group (chi2 = 14.5; df = 4, p = .006) confirms an association between this apoe molecular variant and dementia in elderly spaniards. |
2003-03-26 |
2023-08-12 |
human |
| Mary N Haan, Dan M Mungas, Hector M Gonzalez, Teresa A Ortiz, Ananth Acharya, William J Jagus. Prevalence of dementia in older latinos: the influence of type 2 diabetes mellitus, stroke and genetic factors. Journal of the American Geriatrics Society. vol 51. issue 2. 2003-03-25. PMID:12558712. |
to estimate dementia prevalence in older mexican americans, determine the distribution of dementia by etiology, and evaluate the contribution of type 2 diabetes mellitus, stroke, and apolipoprotein e (apoe) genotype to dementia. |
2003-03-25 |
2023-08-12 |
Not clear |
| Asha Naidu, Qiang Xu, Rosanne Catalano, Barbara Cordel. Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468034. |
our finding that protein geranylgeranylation is required for apoe secretion in the brain parenchyma provides another contributing mechanism to explain the effective properties of statins against the development of dementia. |
2003-02-25 |
2023-08-12 |
Not clear |
| A Frank, E Díez-Tejedor, M J Bullido, F Valdivieso, P Barreir. APOE genotype in cerebrovascular disease and vascular dementia. Journal of the neurological sciences. vol 203-204. 2003-01-23. PMID:12417379. |
apoe genotype in cerebrovascular disease and vascular dementia. |
2003-01-23 |
2023-08-12 |
Not clear |
| A Frank, E Díez-Tejedor, M J Bullido, F Valdivieso, P Barreir. APOE genotype in cerebrovascular disease and vascular dementia. Journal of the neurological sciences. vol 203-204. 2003-01-23. PMID:12417379. |
the fact that the allele epsilon 4 of the apolipoprotein e (apoe) gene could act like a risk factor not only in late-onset familial and sporadic alzheimer's disease (ad) but also in cerebrovascular disease (cvd) and vascular dementia (vad) is still controversial. |
2003-01-23 |
2023-08-12 |
Not clear |
| Latchezar Traykov, Anne-Sophie Rigaud, Sophie Baudic, Alain Smagghe, François Boller, Françoise Forett. Apolipoprotein E epsilon 4 allele frequency in demented and cognitively impaired patients with and without cerebrovascular disease. Journal of the neurological sciences. vol 203-204. 2003-01-23. PMID:12417380. |
controversy exists regarding the apolipoprotein e (apoe) epsilon 4 allele association with vascular dementia (vad). |
2003-01-23 |
2023-08-12 |
human |
| Latchezar Traykov, Anne-Sophie Rigaud, Sophie Baudic, Alain Smagghe, François Boller, Françoise Forett. Apolipoprotein E epsilon 4 allele frequency in demented and cognitively impaired patients with and without cerebrovascular disease. Journal of the neurological sciences. vol 203-204. 2003-01-23. PMID:12417380. |
we examined the apoe phenotypes in a sample of 452 subjects: 219 with ad, 45 with vad, 62 with mixed dementia (md), 45 with mild cognitive impairment (mci) without cvd, 27 in which vascular disease was the most probable cause of cognitive decline (vascular mild cognitive impairment, vmci) and 54 normal controls (nc). |
2003-01-23 |
2023-08-12 |
human |
| H-M Huang, Y-M Kuo, H-C Ou, C-C Lin, L-J Chu. Apolipoprotein E polymorphism in various dementias in Taiwan Chinese population. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 11. 2003-01-22. PMID:12454737. |
to verify the association between apoe4 frequency and various dementias in taiwan chinese individuals, apoe genotypes were determined in patients with dementia of alzheimer's type (ad), vascular dementia (vd), dementias due to other general medical conditions (od), and dementia of alzheimer's type with cerebral vascular disease (mixed type dementia; md). |
2003-01-22 |
2023-08-12 |
Not clear |
| Kelly L Lange, Mark W Bondi, David P Salmon, Douglas Galasko, Dean C Delis, Ronald G Thomas, Leon J Tha. Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of APOE genotype. Journal of the International Neuropsychological Society : JINS. vol 8. issue 7. 2002-11-26. PMID:12405546. |
results revealed a precipitous decline in verbal memory abilities 1 to 2 years prior to the onset of the dementia syndrome, but there was little effect of apoe genotype on the rate of this memory decline. |
2002-11-26 |
2023-08-12 |
human |
| Scott M Hofer, Helen Christensen, Andrew J Mackinnon, Ailsa E Korten, Anthony F Jorm, Alexander S Henderson, Simon Eastea. Change in cognitive functioning associated with apoE genotype in a community sample of older adults. Psychology and aging. vol 17. issue 2. 2002-11-25. PMID:12061406. |
the results of latent growth curve analyses are reported for individuals genotyped for apoe at the 2nd measurement occasion (n = 601) and for a subsample of individuals without probable or definite dementia during the 1st or 2nd occasion (n = 434). |
2002-11-25 |
2023-08-12 |
Not clear |
| T Anttila, E-L Helkala, M Kivipelto, M Hallikainen, K Alhainen, H Heinonen, A Mannermaa, J Tuomilehto, H Soininen, A Nissine. Midlife income, occupation, APOE status, and dementia: a population-based study. Neurology. vol 59. issue 6. 2002-10-16. PMID:12297572. |
midlife income, occupation, apoe status, and dementia: a population-based study. |
2002-10-16 |
2023-08-12 |
Not clear |