| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel H Aslan, M Katherine Sayre, Pradyumna K Bharadwaj, Madeline Ally, Silvio Maltagliati, Mark H C Lai, Rand R Wilcox, Yann C Klimentidis, Gene E Alexander, David A Raichle. Associations Between Walking Pace, APOE-ε4 Genotype, and Brain Health in Middle-Aged to Older Adults. Medicine and science in sports and exercise. 2025-01-09. PMID:39780372. |
poor physical function and possession of the e4 allele of the apolipoprotein e (apoe) gene are each associated with increased dementia risk, but it is unclear how these exposures interact to influence brain health. |
2025-01-09 |
2025-01-13 |
human |
| Francesca Mariani, Andres Damian, Alice Leites, Lucia Cortabarría, Laura Bocos, Sofia Santero, Valeria Contreras, Rodolfo Ferrando, Margarita García-Fontes, Laura Reyes, Florencia Arredondo, Juan Andrés Abin-Carriquiry, Mercedes Menendez, Alejandra Amestoy, Maren Torheim, Roberto Superchi, Ramon Suarez, Fabian Preciozzi, Laura Uriarte, Leandro Dansilio, Sergio Dansilio, Ana Charamelo, Ricardo Allegri, Paulo Caramelli, Francisco Lopera, Ricardo Nitrini, Gustavo Sevlever, Ana Luisa Sosa, Ismael Luis Calandri, Lucia Crivelli, Rosa Maria Salinas-Contreras, Claudia Kimie Suemoto, Lina Marcela Vellila, Monica Sanches Yassud. Clinical Manifestations. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 3. 2025-01-03. PMID:39750386. |
we describe the distribution of apoe alleles in healthy subjects at risk of developing dementia in uruguay, and its association with cognitive assessment and risk factors for dementia. |
2025-01-03 |
2025-01-05 |
human |
| Li Shang, Liling Dong, Chenhui Mao, Xinying Huang, Shanshan Chu, Wei Jin, Tianyi Wang, Bo Li, Jialu Bao, Yuyue Qiu, Yuhan Jiang, Yixuan Huang, Jing Ga. Clinical Manifestations. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 3. 2025-01-03. PMID:39750702. |
the aim of this study was to clarify the effect of apoe ε2 on different cognitive domains in dementia patients. |
2025-01-03 |
2025-01-05 |
Not clear |
| Jiao-Jiao Ren, Zhi-Hao Li, Wen-Fang Zhong, Pei-Liang Chen, Xiao-Meng Wang, Wei-Qi Song, Chen Ma. Salt added at the table, APOE genotype and incident dementia. Maturitas. vol 193. 2024-12-27. PMID:39729935. |
salt added at the table, apoe genotype and incident dementia. |
2024-12-27 |
2024-12-30 |
Not clear |
| Namitha Thalekkara Haridas, Jose M Sanchez-Bornot, Paula L McClean, KongFatt Wong-Li. Autoencoder imputation of missing heterogeneous data for Alzheimer's disease classification. Healthcare technology letters. vol 11. issue 6. 2024-12-25. PMID:39720752. |
the authors focused on extreme (≥40%) missing at random of key features which depend on ad progression; identified as the history of a mother having ad, apoe ε4 alleles, and clinical dementia rating. |
2024-12-25 |
2024-12-27 |
Not clear |
| Sarah M Philippi, Kailash Bp, Towfique Raj, Joseph M Castellan. APOE genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia. Annals of clinical and translational neurology. 2024-12-17. PMID:39689057. |
apoe genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia. |
2024-12-17 |
2024-12-21 |
human |
| Victoria J Williams, Ralph Trane, Kamil Sicinski, Pamela Herd, Michal Engelman, Sanjay Asthan. Midlife and late-life environmental exposures on dementia risk in the Wisconsin Longitudinal Study: The modifying effects of ApoE. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-11-22. PMID:39576060. |
midlife and late-life environmental exposures on dementia risk in the wisconsin longitudinal study: the modifying effects of apoe. |
2024-11-22 |
2024-11-24 |
Not clear |
| Yuriko Katsumata, Xian Wu, Khine Zin Aung, David W Fardo, Davis C Woodworth, S Ahmad Sajjadi, Sandra O Tomé, Dietmar Rudolf Thal, Juan C Troncoso, Koping Chang, Charles Mock, Peter T Nelso. Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer's pathologies. Acta neuropathologica. vol 148. issue 1. 2024-11-15. PMID:39546031. |
in terms of clinical impact, participants with pure late-nc tended to die after having received a diagnosis of dementia: 56% died with dementia among apoe ε4 non-carrier participants, comparable to 61% with pure adnc. |
2024-11-15 |
2024-11-18 |
human |
| Mollie Monnig, Krish Sha. Linking alcohol use to Alzheimer's disease: Interactions with aging and APOE along immune pathways. Medical research archives. vol 12. issue 8. 2024-11-15. PMID:39544182. |
carriers of the apoe ε4 allele show elevated risk of dementia in relation to several lifestyle factors, including alcohol use. |
2024-11-15 |
2024-11-17 |
Not clear |
| Michelle M Dunk, Ira Driscoll, Mark A Espeland, Kathleen M Hayden, Simin Liu, Rami Nassir, Ginny Natale, Aladdin H Shadyab, Jo Ann E Manso. Relationships between APOE, Type 2 Diabetes, and Cardiovascular Disease in Postmenopausal Women. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024-10-04. PMID:39364911. |
the apolipoprotein e (apoe) ε4 allele, type 2 diabetes mellitus (t2dm), and cardiovascular disease (cvd) are well-established risk factors for dementia. |
2024-10-04 |
2024-10-07 |
Not clear |
| Michelle M Dunk, Ira Driscoll, Mark A Espeland, Kathleen M Hayden, Simin Liu, Rami Nassir, Ginny Natale, Aladdin H Shadyab, Jo Ann E Manso. Relationships between APOE, Type 2 Diabetes, and Cardiovascular Disease in Postmenopausal Women. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024-10-04. PMID:39364911. |
relationships between apoe and incidence of t2dm and cvd are not fully understood but may shed light on the mechanisms underlying dementia pathogenesis. |
2024-10-04 |
2024-10-07 |
Not clear |
| Feng Deng, Maria-Eleni Dounavi, Emanuele R G Plini, Karen Ritchie, Graciela Muniz-Terrera, Siobhan Hutchinson, Paresh Malhotra, Craig W Ritchie, Brian Lawlor, Lorina Nac. Cardiovascular risk of dementia is associated with brain-behaviour changes in cognitively healthy, middle-aged individuals. Neurobiology of aging. vol 144. 2024-09-18. PMID:39293163. |
associations of cognition and fc with apolipoprotein ε4 (apoe ε4) genotype, family history of dementia, and the cardiovascular risk factors, aging, and incidence of dementia (caide) score were investigated. |
2024-09-18 |
2024-09-21 |
Not clear |
| Sisi Yang, Ziliang Ye, Panpan He, Yuanyuan Zhang, Mengyi Liu, Chun Zhou, Yanjun Zhang, Xiaoqin Gan, Yu Huang, Hao Xiang, Xianhui Qi. Plasma proteomics for risk prediction of Alzheimer's disease in the general population. Aging cell. 2024-09-10. PMID:39252463. |
we aimed to develop and validate a protein risk score for predicting alzheimer's disease (ad) and compare its performance with a validated clinical risk model (cognitive health and dementia risk index for ad [cogdrisk-ad]) and apolipoprotein e (apoe) genotypes. |
2024-09-10 |
2024-09-13 |
human |
| Tamara Shiner, Gitit Kavé, Anat Mirelman, Keren Regev, Yoav Piura, Orly Goldstein, Mali Gana Weisz, Anat Bar-Shira, Tanya Gurevich, Avi Orr-Urtreger, Roy N Alcalay, Nir Giladi, Noa Bregma. Effect of GBA1 Mutations and APOE Polymorphisms on Survival and Progression Among Ashkenazi Jews with Dementia with Lewy Bodies. Movement disorders : official journal of the Movement Disorder Society. 2024-08-30. PMID:39212252. |
effect of gba1 mutations and apoe polymorphisms on survival and progression among ashkenazi jews with dementia with lewy bodies. |
2024-08-30 |
2024-09-04 |
Not clear |
| Miguel Baquero, Laura Ferré-González, Lourdes Álvarez-Sánchez, Inés Ferrer-Cairols, Lorena García-Vallés, Mar Peretó, Luis Raga, Gemma García-Lluch, Carmen Peña-Bautista, Beatriz Muria, Aitana Prieto, Inés Jareño, Consuelo Cháfer-Pericá. Insights from a 7-Year Dementia Cohort (VALCODIS): ApoE Genotype Evaluation. Journal of clinical medicine. vol 13. issue 16. 2024-08-29. PMID:39200877. |
insights from a 7-year dementia cohort (valcodis): apoe genotype evaluation. |
2024-08-29 |
2024-09-01 |
Not clear |
| Petrice M Cogswell, Trevor J Andrews, Jerome A Barakos, Frederik Barkhof, Suzie Bash, Marc Daniel Benayoun, Gloria C Chiang, Ana M Franceschi, Clifford R Jack, Jay J Pillai, Tina Young Poussaint, Cyrus A Raji, Vijay K Ramanan, Jody Tanabe, Lawrence Tanenbaum, Christopher T Whitlow, Fang F Yu, Greg Zaharchuk, Michael Zeinah, Tammie S Benzinge. Alzheimer's Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for ARIA Monitoring. AJNR. American journal of neuroradiology. 2024-08-23. PMID:39179297. |
based on consensus discussion within an expanded asnr alzheimer's, aria, and dementia study group, we will: (1) summarize the fda guidelines for evaluation of radiographic aria; (2) review the three key mri sequences for aria monitoring and standardized imaging protocols based on asnr-industry collaborations; (3) provide imaging recommendations for three key patient scenarios; (4) highlight the role of the radiologist in the care team for this population; (5) discuss implementation of mri protocols to detect aria in diverse practice settings; and (6) present results of the 2023 asnr international neuroradiologist practice survey on dementia and aria imaging.abbreviations: ad = alzheimer's disease; aria = amyloid-related imaging abnormalities; apoe = apolipoprotein-e; cms = centers for medicare & medicaid services; mci = mild cognitive impairment. |
2024-08-23 |
2024-08-27 |
Not clear |
| Rodrigo Canovas, Paul Maruff, Christopher J Fowler, Stephanie R Rainey-Smith, Colin L Masters, James D Doeck. Clinical Manifestations. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 19 Suppl 18. 2024-08-07. PMID:39112039. |
positive ad biomarkers, (e.g., amyloid, tau, or apoe ε4 carriage), increase rates of cognitive decline and transition to dementia. |
2024-08-07 |
2024-08-10 |
Not clear |
| Paul C R Hopkins, Claire Troakes, Andrew King, Guy Tea. Transmembrane and coiled-coil 2 associates with Alzheimer's disease pathology in the human brain. Brain pathology (Zurich, Switzerland). 2024-07-31. PMID:39084860. |
at the protein level, western blots of human brain extracts revealed that human brain-derived tmcc2 exists as at least three isoforms, the relative abundance of which varied between the temporal gyrus and cerebellum and was influenced by apoe and/or dementia status. |
2024-07-31 |
2024-08-03 |
human |
| Courtney M Kloske, Michael E Belloy, Elizabeth E Blue, Gregory R Bowman, Maria C Carrillo, Xiaoying Chen, Ornit Chiba-Falek, Albert A Davis, Gilbert Di Paolo, Francesca Garretti, David Gate, Lesley R Golden, Jay W Heinecke, Joachim Herz, Yadong Huang, Costantino Iadecola, Lance A Johnson, Takahisa Kanekiyo, Celeste M Karch, Anastasia Khvorova, Sascha J Koppes-den Hertog, Bruce T Lamb, Paige E Lawler, Yann Le Guen, Alexandra Litvinchuk, Chia-Chen Liu, Simin Mahinrad, Edoardo Marcora, Claudia Marino, Danny M Michaelson, Justin J Miller, Josh M Morganti, Priyanka S Narayan, Michel S Naslavsky, Marlies Oosthoek, Kapil V Ramachandran, Abhirami Ramakrishnan, Ana-Caroline Raulin, Aiko Robert, Rasha N M Saleh, Claire Sexton, Nilomi Shah, Francis Shue, Isabel J Sible, Andrea Soranno, Michael R Strickland, Julia Tcw, Manon Thierry, Li-Huei Tsai, Ryan A Tuckey, Jason D Ulrich, Rik van der Kant, Na Wang, Cheryl L Wellington, Stacie C Weninger, Hussein N Yassine, Na Zhao, Guojun Bu, Alison M Goate, David M Holtzma. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-07-20. PMID:39031528. |
advancements in apoe and dementia research: highlights from the 2023 aaic advancements: apoe conference. |
2024-07-20 |
2024-07-24 |
Not clear |
| Zhao Yao, Jie Wang, Tianfang Zhang, Hongjing Ai, Zeinab Abdelrahman, Xiaohong Wu, Daming Wang, Fenfen Chen, Ziwei Zhang, Xiaosheng Wang, Zuyun Liu, Zuobing Che. Age, sex, and APOE gene-specific associations between dynapenic obesity and dementia in a large cohort. The journal of nutrition, health & aging. vol 28. issue 8. 2024-07-10. PMID:38986174. |
age, sex, and apoe gene-specific associations between dynapenic obesity and dementia in a large cohort. |
2024-07-10 |
2024-07-13 |
Not clear |