| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Senanarong, K Harnphadungkit, P Lertrit, C Mitrpant, S Udompunthurak, C Limwong, N Prayoonwiwat, N Poungvari. Experience of ApoE study in Thai elderly. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 84. issue 2. 2001-05-21. PMID:11336076. |
the association between apoe e4 and dementia is reported in alzheimer's disease and other dementia such as in multi-infarct dementia. |
2001-05-21 |
2023-08-12 |
Not clear |
| R Cacabelos, A Alvarez, L Fenández-Novoa, V R Lombard. A pharmacogenomic approach to Alzheimer's disease. Acta neurologica Scandinavica. Supplementum. vol 176. 2001-05-17. PMID:11261800. |
using a matrix genetic model, including apoe, ps1 and ps2 allelic variants, we have studied the distribution of 36 different genotypes in the ad population (n= 479) and the genotype-related cognitive response to a multifactorial therapy in ad patients with mild-to-moderate dementia. |
2001-05-17 |
2023-08-12 |
Not clear |
| M F Jefferson, S Burlinson, A Burns, D Mann, S Pickering-Brown, F Owen, C Sriwardhana, N Pendleton, M A Hora. Clinical features of dementia associated with apolipoprotein epsilon4: discrimination with a neural network genetic algorithm. International journal of geriatric psychiatry. vol 16. issue 1. 2001-04-12. PMID:11180489. |
it is unclear whether the apoe epsilon4 allele is associated with distinct clinical features in dementia. |
2001-04-12 |
2023-08-12 |
Not clear |
| R Frikke-Schmidt, B G Nordestgaard, D Thudium, M L Moes Grønholdt, A Tybjaerg-Hanse. APOE genotype predicts AD and other dementia but not ischemic cerebrovascular disease. Neurology. vol 56. issue 2. 2001-04-05. PMID:11160955. |
apoe genotype predicts ad and other dementia but not ischemic cerebrovascular disease. |
2001-04-05 |
2023-08-12 |
Not clear |
| R Frikke-Schmidt, B G Nordestgaard, D Thudium, M L Moes Grønholdt, A Tybjaerg-Hanse. APOE genotype predicts AD and other dementia but not ischemic cerebrovascular disease. Neurology. vol 56. issue 2. 2001-04-05. PMID:11160955. |
the hypothesis that apoe genotype, through its effect on lipoproteins, is a common risk factor for ischemic cerebrovascular disease (icvd), ad, and other dementia (od) was tested. |
2001-04-05 |
2023-08-12 |
Not clear |
| B Paradowski, M Szczepaniak, T Dobosz, M Sasiade. [Apolipoprotein E(ApoE)and tau protein in Alzheimer type dementia]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 9. issue 53. 2001-03-08. PMID:11204323. |
[apolipoprotein e(apoe)and tau protein in alzheimer type dementia]. |
2001-03-08 |
2023-08-12 |
Not clear |
| Y Ihara, T Hayabara, K Sasaki, R Kawada, Y Nakashima, S Kurod. Relationship between oxidative stress and apoE phenotype in Alzheimer's disease. Acta neurologica Scandinavica. vol 102. issue 6. 2001-02-15. PMID:11125747. |
to investigate the relationship between oxidative stress and apoe phenotype in dementia of alzheimer type (dat). |
2001-02-15 |
2023-08-12 |
Not clear |
| N Durany, P Riederer, F F Cruz-Sánche. Apolipoprotein E genotype in Spanish schizophrenic patients. Psychiatric genetics. vol 10. issue 2. 2001-01-26. PMID:10994644. |
schizophrenia is in some cases associated with cognitive impairment similar to that of alzheimer patients; therefore, one may postulate that the apoe gene, whose role in the dementia of alzheimer's type has been clearly demonstrated, may also be involved in schizophrenia. |
2001-01-26 |
2023-08-12 |
Not clear |
| J M Johnston, V Nazar-Stewart, S F Kelsey, M I Kamboh, M Gangul. Relationships between cerebrovascular events, APOE polymorphism and Alzheimer's disease in a community sample. Neuroepidemiology. vol 19. issue 6. 2000-12-27. PMID:11060506. |
to investigate whether the apoe*4 allele modified the relationship between cerebrovascular events and alzheimer's disease (ad), we collected evidence of previous stroke or transient ischemic attack (tia) and determined apoe genotype among 102 subjects with ad and 375 nondemented subjects in a community-based study of dementia. |
2000-12-27 |
2023-08-12 |
human |
| C K Rosenberg, M A Pericak-Vance, A M Saunders, J R Gilbert, P C Gaskell, C M Hulett. Lewy body and Alzheimer pathology in a family with the amyloid-beta precursor protein APP717 gene mutation. Acta neuropathologica. vol 100. issue 2. 2000-12-22. PMID:10963361. |
a cousin without the app717 mutation who was apoe 3, 4, developed dementia at age 60 and died at age 75. |
2000-12-22 |
2023-08-12 |
Not clear |
| T Rodriguez Martin, A M Calella, S Silva, E Munna, P Modena, R Chiesa, S Terrevazzi, R M Ruggieri, R Palermo, F Piccoli, R Confalonieri, P Tiraboschi, C Fragiacomo, P Quadri, U Lucca, G Forlon. Apolipoprotein E and intronic polymorphism of presenilin 1 and alpha-1-antichymotrypsin in Alzheimer's disease and vascular dementia. Dementia and geriatric cognitive disorders. vol 11. issue 5. 2000-10-11. PMID:10940674. |
apolipoprotein e (apoe) genotypes, presenilin 1 (ps-1) and alpha(1)-antichymotrypsin (act) polymorphism and the association of the genotypes were examined in patients with alzheimer's disease (ad, n = 121) or vascular dementia (vd, n = 68) in comparison with elderly controls (n = 125). |
2000-10-11 |
2023-08-12 |
Not clear |
| J Shi, G Perry, M A Smith, R P Friedlan. Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease. Neurobiology of aging. vol 21. issue 2. 2000-08-24. PMID:10867221. |
here, we review studies on the cerebral vasculature, cardiac vasculature, and apoe that lead us to contend that vascular abnormalities are likely an important mechanism underlying dementia. |
2000-08-24 |
2023-08-12 |
Not clear |
| B S Harhangi, M C de Rijk, C M van Duijn, C Van Broeckhoven, A Hofman, M M Bretele. APOE and the risk of PD with or without dementia in a population-based study. Neurology. vol 54. issue 6. 2000-08-18. PMID:10746597. |
apoe and the risk of pd with or without dementia in a population-based study. |
2000-08-18 |
2023-08-12 |
Not clear |
| B S Harhangi, M C de Rijk, C M van Duijn, C Van Broeckhoven, A Hofman, M M Bretele. APOE and the risk of PD with or without dementia in a population-based study. Neurology. vol 54. issue 6. 2000-08-18. PMID:10746597. |
to study the association between apoe genotype and pd with or without dementia. |
2000-08-18 |
2023-08-12 |
Not clear |
| S Y Bookheimer, M H Strojwas, M S Cohen, A M Saunders, M A Pericak-Vance, J C Mazziotta, G W Smal. Patterns of brain activation in people at risk for Alzheimer's disease. The New England journal of medicine. vol 343. issue 7. 2000-08-17. PMID:10944562. |
the epsilon4 allele of the apolipoprotein e gene (apoe) is the chief known genetic risk factor for alzheimer's disease, the most common cause of dementia late in life. |
2000-08-17 |
2023-08-12 |
Not clear |
| T Katsuya, N Sato, T Asai, M Fukuda, S Takiuchi, Y Fu, R Hanayama, A Moriguchi, H Rakugi, J Higaki, T Ogihar. Association of polymorphism in the promoter region of the apolipoprotein E gene with diastolic blood pressure in normotensive Japanese. Hypertension research : official journal of the Japanese Society of Hypertension. vol 23. issue 3. 2000-08-04. PMID:10821138. |
the epsilon4 allele of apolipoprotein e (apoe) is reported to be a genetic risk factor of atherosclerosis through hyperlipidemia and late-onset alzheimer's dementia. |
2000-08-04 |
2023-08-12 |
human |
| J W Knittweis, W A McMulle. The effect of apoE on dementia is not through atherosclerosis: the Rotterdam study. Neurology. vol 54. issue 12. 2000-07-31. PMID:10881278. |
the effect of apoe on dementia is not through atherosclerosis: the rotterdam study. |
2000-07-31 |
2023-08-12 |
Not clear |
| M Nishiyama, Y Kato, M Hashimoto, S Yukawa, K Omor. Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method. Journal of epidemiology. vol 10. issue 3. 2000-07-19. PMID:10860300. |
although, it was not strongly related to the severity of senile dementia, a weak association between the apoe genotype and the severity of dementia was suggested. |
2000-07-19 |
2023-08-12 |
Not clear |
| M Nishiyama, Y Kato, M Hashimoto, S Yukawa, K Omor. Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method. Journal of epidemiology. vol 10. issue 3. 2000-07-19. PMID:10860300. |
the results suggest that the apoe epsilon 4 genotype and the mthfr mutation are associated with the clinical phenotype and the clinical onset of senile dementia. |
2000-07-19 |
2023-08-12 |
Not clear |
| S M Pickering-Brown, F Owen, A Isaacs, J Snowden, A Varma, D Neary, R Furlong, S E Daniel, N J Cairns, D M Man. Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology. Experimental neurology. vol 163. issue 2. 2000-07-17. PMID:10833320. |
here we have investigated the frequency of the epsilon4 allele of the apolipoprotein (apoe) gene in ftd and in other non-alzheimer forms of dementia related to ftd such as motor neurone disease dementia, semantic dementia, progressive aphasia, progressive supranuclear palsy, and corticobasal degeneration. |
2000-07-17 |
2023-08-12 |
Not clear |