Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Tomoyuki Nagata, Nobuyuki Kobayashi, Shunichiro Shinagawa, Hisashi Yamada, Kazuhiro Kondo, Kazuhiko Nakayam. Plasma BDNF levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or Alzheimer disease. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 4. 2014-11-07. PMID:24253237. |
next, we investigated the correlation between the plasma bdnf level and the behavioral pathology in alzheimer disease (behave-ad) subscale scores, which reflect neuropsychiatric symptoms. |
2014-11-07 |
2023-08-12 |
Not clear |
Jenq-Lin Yang, Yu-Ting Lin, Pei-Chin Chuang, Vilhelm A Bohr, Mark P Mattso. BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1. Neuromolecular medicine. vol 16. issue 1. 2014-10-28. PMID:24114393. |
bdnf levels are reduced in brain regions affected in alzheimer's, parkinson's, and huntington's diseases, and elevation of bdnf levels can ameliorate neuronal dysfunction and degeneration in experimental models of these diseases. |
2014-10-28 |
2023-08-12 |
mouse |
Nirmal Sonali, Manjari Tripathi, Rajesh Sagar, Subbiah Vivekanandha. Val66Met polymorphism and BDNF levels in Alzheimer's disease patients in North Indian population. The International journal of neuroscience. vol 123. issue 6. 2014-10-24. PMID:23270505. |
val66met polymorphism and bdnf levels in alzheimer's disease patients in north indian population. |
2014-10-24 |
2023-08-12 |
Not clear |
Nirmal Sonali, Manjari Tripathi, Rajesh Sagar, Subbiah Vivekanandha. Val66Met polymorphism and BDNF levels in Alzheimer's disease patients in North Indian population. The International journal of neuroscience. vol 123. issue 6. 2014-10-24. PMID:23270505. |
analysis of serum brain-derived neurotrophic factor (bdnf) levels in alzheimer's disease (ad), amnestic mild cognitive impairment (amci) and controls with bdnf gene polymorphism and cognitive function were investigated. |
2014-10-24 |
2023-08-12 |
Not clear |
Flávia Gomes de Melo Coelho, Thays Martins Vital, Angelica Miki Stein, Franciel José Arantes, André Veloso Rueda, Rosana Camarini, Elizabeth Teodorov, Ruth Ferreira Santos-Galduró. Acute aerobic exercise increases brain-derived neurotrophic factor levels in elderly with Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 39. issue 2. 2014-10-21. PMID:24164734. |
studies indicate the involvement of brain-derived neurotrophic factor (bdnf) in the pathogenesis of alzheimer's disease (ad). |
2014-10-21 |
2023-08-12 |
Not clear |
Tadahiro Numakaw. Possible protective action of neurotrophic factors and natural compounds against common neurodegenerative diseases. Neural regeneration research. vol 9. issue 16. 2014-10-15. PMID:25317165. |
it has been suggested that altered levels/function of brain-derived neurotrophic factor (bdnf) play a role in the pathophysiology of neurodegenerative diseases including alzheimer's disease. |
2014-10-15 |
2023-08-13 |
Not clear |
Jillian C Belrose, Raheleh Masoudi, Bernadeta Michalski, Margaret Fahnestoc. Increased pro-nerve growth factor and decreased brain-derived neurotrophic factor in non-Alzheimer's disease tauopathies. Neurobiology of aging. vol 35. issue 4. 2014-09-29. PMID:24112788. |
alterations in the expression and signaling of brain-derived neurotrophic factor (bdnf) and the precursor to nerve growth factor (ngf), prongf, play a role in the neuronal and cognitive dysfunction of alzheimer's disease. |
2014-09-29 |
2023-08-12 |
human |
Jillian C Belrose, Raheleh Masoudi, Bernadeta Michalski, Margaret Fahnestoc. Increased pro-nerve growth factor and decreased brain-derived neurotrophic factor in non-Alzheimer's disease tauopathies. Neurobiology of aging. vol 35. issue 4. 2014-09-29. PMID:24112788. |
aggregated amyloid-β has been shown to down-regulate specific bdnf transcripts in alzheimer's disease, but the role of tau pathology in neurotrophin dysregulation has not been investigated. |
2014-09-29 |
2023-08-12 |
human |
B Lu, G Nagappan, Y L. BDNF and synaptic plasticity, cognitive function, and dysfunction. Handbook of experimental pharmacology. vol 220. 2014-08-26. PMID:24668475. |
converging evidence now strongly suggest that deficits in bdnf signaling contribute to the pathogenesis of several major diseases and disorders such as huntington's disease, alzheimer's disease, and depression. |
2014-08-26 |
2023-08-12 |
Not clear |
Duygu Gezen-Ak, Erdinç Dursun, Haşmet Hanağası, Başar Bilgiç, Ebba Lohman, Ömür Selin Araz, Irem L Atasoy, Merve Alaylıoğlu, Burak Önal, Hakan Gürvit, Selma Yılmaze. BDNF, TNFα, HSP90, CFH, and IL-10 serum levels in patients with early or late onset Alzheimer's disease or mild cognitive impairment. Journal of Alzheimer's disease : JAD. vol 37. issue 1. 2014-08-11. PMID:23948885. |
bdnf, tnfα, hsp90, cfh, and il-10 serum levels in patients with early or late onset alzheimer's disease or mild cognitive impairment. |
2014-08-11 |
2023-08-12 |
Not clear |
Robyn A Honea, Carlos Cruchaga, Rodrigo D Perea, Andrew J Saykin, Jeffrey M Burns, Daniel R Weinberger, Alison M Goat. Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration. PloS one. vol 8. issue 9. 2014-07-18. PMID:24086677. |
there is accumulating evidence that neurotrophins, like brain-derived neurotrophic factor (bdnf), may impact aging and alzheimer's disease. |
2014-07-18 |
2023-08-12 |
human |
Robyn A Honea, Carlos Cruchaga, Rodrigo D Perea, Andrew J Saykin, Jeffrey M Burns, Daniel R Weinberger, Alison M Goat. Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration. PloS one. vol 8. issue 9. 2014-07-18. PMID:24086677. |
our goal was to test whether bdnf single nucleotide polymorphisms (snps) impact alzheimer's disease-related brain imaging and cognitive markers of disease. |
2014-07-18 |
2023-08-12 |
human |
Young-Je Si. Treadmill exercise alleviates impairment of spatial learning ability through enhancing cell proliferation in the streptozotocin-induced Alzheimer's disease rats. Journal of exercise rehabilitation. vol 10. issue 2. 2014-05-30. PMID:24877042. |
decreased cell proliferation with decrement of bdnf and trkb expressions in the hippocampus were observed in the stz-induced alzheimer's disease rats. |
2014-05-30 |
2023-08-13 |
rat |
Mariacarla Ventriglia, Roberta Zanardini, Cristina Bonomini, Orazio Zanetti, Daniele Volpe, Patrizio Pasqualetti, Massimo Gennarelli, Luisella Bocchio-Chiavett. Serum brain-derived neurotrophic factor levels in different neurological diseases. BioMed research international. vol 2013. 2014-04-07. PMID:24024214. |
consistent evidence indicates the involvement of the brain-derived neurotrophic factor (bdnf) in neurodegenerative disorders such as alzheimer's disease (ad) and parkinson's disease (pd). |
2014-04-07 |
2023-08-12 |
human |
Galit Weinstein, Alexa S Beiser, Seung Hoan Choi, Sarah R Preis, Tai C Chen, Demetrios Vorgas, Rhoda Au, Aleksandra Pikula, Philip A Wolf, Anita L DeStefano, Ramachandran S Vasan, Sudha Seshadr. Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. JAMA neurology. vol 71. issue 1. 2014-03-17. PMID:24276217. |
some prior studies showed lower circulating bdnf in persons with alzheimer disease (ad) compared with control participants; however, it remains uncertain whether reduced levels precede dementia onset. |
2014-03-17 |
2023-08-12 |
human |
Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra D Harrington, Pierrick Bourgeat, Olivier Salvado, David Darby, Peter J Snyder, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Pradeep J Nathan, Paul Maruf. BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease. Neurobiology of aging. vol 34. issue 11. 2014-03-05. PMID:23769397. |
bdnf val66met, aβ amyloid, and cognitive decline in preclinical alzheimer's disease. |
2014-03-05 |
2023-08-12 |
Not clear |
Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra D Harrington, Pierrick Bourgeat, Olivier Salvado, David Darby, Peter J Snyder, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Pradeep J Nathan, Paul Maruf. BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease. Neurobiology of aging. vol 34. issue 11. 2014-03-05. PMID:23769397. |
brain-derived neurotrophic factor (bdnf) val66met polymorphism has previously been implicated in alzheimer's disease (ad)-related cognitive impairment. |
2014-03-05 |
2023-08-12 |
Not clear |
Annamaria Cimini, Roberta Gentile, Barbara D'Angelo, Elisabetta Benedetti, Loredana Cristiano, Maria Laura Avantaggiati, Antonio Giordano, Claudio Ferri, Giovambattista Desider. Cocoa powder triggers neuroprotective and preventive effects in a human Alzheimer's disease model by modulating BDNF signaling pathway. Journal of cellular biochemistry. vol 114. issue 10. 2014-02-28. PMID:23554028. |
cocoa powder triggers neuroprotective and preventive effects in a human alzheimer's disease model by modulating bdnf signaling pathway. |
2014-02-28 |
2023-08-12 |
human |
W Zhang, P J Wang, M H Li, X L Gao, G J Gu, Z H Sha. 1H-MRS can monitor metabolites changes of lateral intraventricular BDNF infusion into a mouse model of Alzheimer's disease in vivo. Neuroscience. vol 245. 2014-02-19. PMID:23608100. |
1h-mrs can monitor metabolites changes of lateral intraventricular bdnf infusion into a mouse model of alzheimer's disease in vivo. |
2014-02-19 |
2023-08-12 |
mouse |
Tomi Rantamäki, Susanna Kemppainen, Henri Autio, Saara Stavén, Hennariikka Koivisto, Masami Kojima, Hanna Antila, Pasi O Miettinen, Elisa Kärkkäinen, Nina Karpova, Liisa Vesa, Lothar Lindemann, Marius C Hoener, Heikki Tanila, Eero Castré. The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease. PloS one. vol 8. issue 7. 2014-02-07. PMID:23844236. |
the impact of bdnf gene deficiency to the memory impairment and brain pathology of appswe/ps1de9 mouse model of alzheimer's disease. |
2014-02-07 |
2023-08-12 |
mouse |