Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jia Chen, Xiaomin Liang, Binghu Li, Xiaojiang Jiang, Zhiqiang X. Gender-related association of brain-derived neurotrophic factor gene 196A/G polymorphism with Alzheimer's disease--a meta-analysis including 6854 cases and 6868 controls. The International journal of neuroscience. vol 124. issue 10. 2015-05-12. PMID:24279351. |
epidemiological studies have evaluated the associations between brain-derived neurotrophic factor (bdnf) 196a/g gene polymorphism and alzheimer's disease (ad) risk. |
2015-05-12 |
2023-08-12 |
Not clear |
Angela Passaro, Edoardo Dalla Nora, Mario L Morieri, Cecilia Soavi, Juana M Sanz, Amedeo Zurlo, Renato Fellin, Giovanni Zulian. Brain-derived neurotrophic factor plasma levels: relationship with dementia and diabetes in the elderly population. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 70. issue 3. 2015-04-17. PMID:24621946. |
we investigated the relationship between plasma bdnf levels, dementia, and diabetes in a sample of 164 community-dwelling elderly individuals, including 50 participants with vascular dementia, 44 with late onset alzheimer's disease, 23 with cerebrovascular disease not dementia, and 47 controls (c). |
2015-04-17 |
2023-08-12 |
human |
Angela Passaro, Edoardo Dalla Nora, Mario L Morieri, Cecilia Soavi, Juana M Sanz, Amedeo Zurlo, Renato Fellin, Giovanni Zulian. Brain-derived neurotrophic factor plasma levels: relationship with dementia and diabetes in the elderly population. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 70. issue 3. 2015-04-17. PMID:24621946. |
a progressive reductions of bdnf plasma levels from c (383.9 ± 204.6 pg/ml), to cerebrovascular disease not dementia (377.1 ± 130.2), to vascular dementia (313.3 ± 114.8), to late onset alzheimer's disease (264.7 ± 147.7) was observed, (late onset alzheimer's disease vs c, p: .03; late onset alzheimer's disease vs cerebrovascular disease not dementia, p: .002). |
2015-04-17 |
2023-08-12 |
human |
Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayam. Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease. Dementia and geriatric cognitive disorders extra. vol 5. issue 1. 2015-04-15. PMID:25873928. |
association between dna methylation of the bdnf promoter region and clinical presentation in alzheimer's disease. |
2015-04-15 |
2023-08-13 |
Not clear |
Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayam. Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease. Dementia and geriatric cognitive disorders extra. vol 5. issue 1. 2015-04-15. PMID:25873928. |
in the present study, we examined whether dna methylation of the brain-derived neurotrophic factor (bdnf) promoter is associated with the manifestation and clinical presentation of alzheimer's disease (ad). |
2015-04-15 |
2023-08-13 |
Not clear |
Laura Psotta, Carolin Rockahr, Michael Gruss, Elmar Kirches, Katharina Braun, Volkmar Lessmann, Jörg Bock, Thomas Endre. Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model. Frontiers in behavioral neuroscience. vol 9. 2015-04-08. PMID:25852506. |
impact of an additional chronic bdnf reduction on learning performance in an alzheimer mouse model. |
2015-04-08 |
2023-08-13 |
mouse |
Laura Psotta, Carolin Rockahr, Michael Gruss, Elmar Kirches, Katharina Braun, Volkmar Lessmann, Jörg Bock, Thomas Endre. Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model. Frontiers in behavioral neuroscience. vol 9. 2015-04-08. PMID:25852506. |
there is increasing evidence that brain-derived neurotrophic factor (bdnf) plays a crucial role in alzheimer's disease (ad) pathology. |
2015-04-08 |
2023-08-13 |
mouse |
Filippo Vairo, Fernanda Sperb-Ludwig, Matheus Wilke, Kristiane Michellin-Tirelli, Cristina Netto, Eurico Camargo Neto, Ida Vanessa Doederlein Schwart. Brain-derived neurotrophic factor expression increases after enzyme replacement therapy in Gaucher disease. Journal of neuroimmunology. vol 278. 2015-03-23. PMID:25468270. |
a reduction in bdnf expression has been reported in patients with parkinson's disease, alzheimer's disease and dementia with lewy bodies. |
2015-03-23 |
2023-08-13 |
Not clear |
André Jerónimo-Santos, Vânia L Batalha, Christa E Müller, Younis Baqi, Ana Maria Sebastião, Luisa V Lopes, Maria José Diógene. Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP. Neuropharmacology. vol 83. 2015-01-29. PMID:24747180. |
impairments in bdnf signalling have been associated to several neurodegenerative disorders such as alzheimer's disease (ad). |
2015-01-29 |
2023-08-13 |
rat |
Jung Hoon Koo, In Su Kwon, Eun Bum Kang, Chang Kuk Lee, Nam Hee Lee, Man Geun Kwon, In Ho Cho, Joon Yong Ch. Neuroprotective effects of treadmill exercise on BDNF and PI3-K/Akt signaling pathway in the cortex of transgenic mice model of Alzheimer's disease. Journal of exercise nutrition & biochemistry. vol 17. issue 4. 2015-01-08. PMID:25566426. |
neuroprotective effects of treadmill exercise on bdnf and pi3-k/akt signaling pathway in the cortex of transgenic mice model of alzheimer's disease. |
2015-01-08 |
2023-08-13 |
mouse |
Robert D Wyse, Gary L Dunbar, Julien Rossigno. Use of genetically modified mesenchymal stem cells to treat neurodegenerative diseases. International journal of molecular sciences. vol 15. issue 2. 2014-12-18. PMID:24463293. |
specifically, glial cell-derived neurotrophic factor (gdnf), nerve growth factor (ngf), and brain derived neurotrophic factor (bdnf) have been recognized as therapeutic trophic factors for parkinson's, alzheimer's and huntington's diseases, respectively. |
2014-12-18 |
2023-08-12 |
Not clear |
Jan Pláteník, Zdeněk Fišar, Richard Buchal, Roman Jirák, Eva Kitzlerová, Martina Zvěřová, Jiří Raboc. GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24334212. |
gsk3β, creb, and bdnf in peripheral blood of patients with alzheimer's disease and depression. |
2014-12-11 |
2023-08-12 |
Not clear |
Jan Pláteník, Zdeněk Fišar, Richard Buchal, Roman Jirák, Eva Kitzlerová, Martina Zvěřová, Jiří Raboc. GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24334212. |
glycogen synthase kinase-3β (gsk3β), camp-response element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) play critical roles in neuronal survival, synaptic plasticity and memory and participate in the pathophysiology of both depressive disorder and alzheimer's disease (ad). |
2014-12-11 |
2023-08-12 |
Not clear |
Atish Prakash, Anil Kuma. Role of nuclear receptor on regulation of BDNF and neuroinflammation in hippocampus of β-amyloid animal model of Alzheimer's disease. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24277156. |
role of nuclear receptor on regulation of bdnf and neuroinflammation in hippocampus of β-amyloid animal model of alzheimer's disease. |
2014-12-01 |
2023-08-12 |
rat |
Naoki Adachi, Tadahiro Numakawa, Misty Richards, Shingo Nakajima, Hiroshi Kunug. New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases. World journal of biological chemistry. vol 5. issue 4. 2014-11-26. PMID:25426265. |
we also introduce implications of bdnf in several brain-related diseases including alzheimer's disease, huntington's disease, depression and schizophrenia. |
2014-11-26 |
2023-08-13 |
Not clear |
Mayara Chaves Faria, Gisele Santos Gonçalves, Natália Pessoa Rocha, Edgar Nunes Moraes, Maria Aparecida Bicalho, Marco Túlio Gualberto Cintra, Jonas Jardim de Paula, Luís Felipe José Ravic de Miranda, Alessandro Clayton de Souza Ferreira, Antônio Lúcio Teixeira, Karina Braga Gomes, Maria das Graças Carvalho, Lirlândia P Sous. Increased plasma levels of BDNF and inflammatory markers in Alzheimer's disease. Journal of psychiatric research. vol 53. 2014-11-24. PMID:24576746. |
increased plasma levels of bdnf and inflammatory markers in alzheimer's disease. |
2014-11-24 |
2023-08-12 |
Not clear |
Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra Harrington, Pierrick Bourgeat, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruf. Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study. PloS one. vol 9. issue 1. 2014-11-12. PMID:24475133. |
effect of bdnf val66met on memory decline and hippocampal atrophy in prodromal alzheimer's disease: a preliminary study. |
2014-11-12 |
2023-08-12 |
Not clear |
Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra Harrington, Pierrick Bourgeat, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruf. Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study. PloS one. vol 9. issue 1. 2014-11-12. PMID:24475133. |
cross-sectional genetic association studies have reported equivocal results on the relationship between the brain-derived neurotrophic factor (bdnf) val66met and risk of alzheimer's disease (ad). |
2014-11-12 |
2023-08-12 |
Not clear |
Tomoyuki Nagata, Nobuyuki Kobayashi, Shunichiro Shinagawa, Hisashi Yamada, Kazuhiro Kondo, Kazuhiko Nakayam. Plasma BDNF levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or Alzheimer disease. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 4. 2014-11-07. PMID:24253237. |
plasma bdnf levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or alzheimer disease. |
2014-11-07 |
2023-08-12 |
Not clear |
Tomoyuki Nagata, Nobuyuki Kobayashi, Shunichiro Shinagawa, Hisashi Yamada, Kazuhiro Kondo, Kazuhiko Nakayam. Plasma BDNF levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or Alzheimer disease. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 4. 2014-11-07. PMID:24253237. |
in the present study, we examined whether neuropsychiatric symptoms were correlated with plasma brain-derived neurotrophic factor (bdnf) levels as a state marker or were associated with the bdnf polymorphism val66met in patients with amnestic mild cognitive impairment (a-mci) or alzheimer disease (ad). |
2014-11-07 |
2023-08-12 |
Not clear |