| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M L Levy, J L Cummings, L A Fairbanks, D L Sultzer, G W Smal. Apolipoprotein E genotype and noncognitive symptoms in Alzheimer's disease. Biological psychiatry. vol 45. issue 4. 1999-05-13. PMID:10071711. |
we sought to clarify the relationship between apoe status and noncognitive symptoms in alzheimer's disease patients. |
1999-05-13 |
2023-08-12 |
Not clear |
| L V Kessing, O S Jørgense. Apolipoprotein E-epsilon 4 frequency in affective disorder. Biological psychiatry. vol 45. issue 4. 1999-05-13. PMID:10071713. |
the epsilon 4 allele of apolipoprotein e (apoe) as well as affective disorder have been found to be associated with alzheimer's disease, but it is unclear whether cognitive impairment in affective disorder or subtypes of affective disorder is mediated by the epsilon 4 allele of apoe. |
1999-05-13 |
2023-08-12 |
Not clear |
| P Kehoe, M Krawczak, P S Harper, M J Owen, A L Jone. Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length. Journal of medical genetics. vol 36. issue 2. 1999-05-12. PMID:10051007. |
apolipoprotein e (apoe) genotype, in turn, is known to influence ao in alzheimer disease, rendering the apoe gene a likely candidate to affect ao in other neurological diseases too. |
1999-05-12 |
2023-08-12 |
Not clear |
| A Salehi, V Gonzalez Martinez, D F Swaa. A sex difference and no effect of ApoE type on the amount of cytoskeletal alterations in the nucleus basalis of Meynert in Alzheimer's disease. Neurobiology of aging. vol 19. issue 6. 1999-05-11. PMID:10192208. |
a sex difference and no effect of apoe type on the amount of cytoskeletal alterations in the nucleus basalis of meynert in alzheimer's disease. |
1999-05-11 |
2023-08-12 |
Not clear |
| A Salehi, V Gonzalez Martinez, D F Swaa. A sex difference and no effect of ApoE type on the amount of cytoskeletal alterations in the nucleus basalis of Meynert in Alzheimer's disease. Neurobiology of aging. vol 19. issue 6. 1999-05-11. PMID:10192208. |
there were no significant differences in the area covered by alz-50 or in the proportion of alz-50-stained neurons in the nucleus basalis of meynert of alzheimer's disease (ad) patients with one or two apoe epsilon4 alleles as compared with those without any apoe e4 allele. |
1999-05-11 |
2023-08-12 |
Not clear |
| J R Oliveira, C M Shimokomaki, P R Brito-Marques, R M Gallindo, M Okuma, L G Maia, P A Otto, M R Passos-Bueno, M Zat. The association of the short variant of the 5-HTTPLR polymorphism and the apoE epsilon4 allele does not increase the risk for late onset Alzheimer's disease. Molecular psychiatry. vol 4. issue 1. 1999-05-07. PMID:10089003. |
the association of the short variant of the 5-httplr polymorphism and the apoe epsilon4 allele does not increase the risk for late onset alzheimer's disease. |
1999-05-07 |
2023-08-12 |
Not clear |
| R D Moir, C S Atwood, D M Romano, M H Laurans, X Huang, A I Bush, J D Smith, R E Tanz. Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations. Biochemistry. vol 38. issue 14. 1999-04-29. PMID:10194381. |
the epsilon 4 allele of apolipoprotein e (apoe) has been found to be a risk factor for late-onset alzheimer's disease (ad). |
1999-04-29 |
2023-08-12 |
human |
| L Bronge, S E Fernaeus, M Blomberg, M Ingelson, L Lannfelt, B Isberg, L O Wahlun. White matter lesions in Alzheimer patients are influenced by apolipoprotein E genotype. Dementia and geriatric cognitive disorders. vol 10. issue 2. 1999-04-27. PMID:10026381. |
to analyse the influence of apolipoprotein e (apoe) genotype on the extent of white matter lesions (wmls) in alzheimer's disease (ad), we examined 60 ad patients with magnetic resonance imaging. |
1999-04-27 |
2023-08-12 |
Not clear |
| S C Samuels, J M Silverman, D B Marin, E R Peskind, S G Younki, D A Greenberg, E Schnur, J Santoro, K L Davi. CSF beta-amyloid, cognition, and APOE genotype in Alzheimer's disease. Neurology. vol 52. issue 3. 1999-04-23. PMID:10025785. |
csf beta-amyloid, cognition, and apoe genotype in alzheimer's disease. |
1999-04-23 |
2023-08-12 |
Not clear |
| B Mazur-Kolecka, J Frackowiak, J Krzeslowska, N Ramakrishna, T Haske, M R Emmerling, W Zhang, K S Kim, H M Wisniewsk. Apolipoprotein E alters metabolism of AbetaPP in cells engaged in beta-amyloidosis. Journal of neuropathology and experimental neurology. vol 58. issue 3. 1999-04-23. PMID:10197820. |
canine smooth muscle cells (smcs), cultured from amyloid-affected brain blood vessels accumulate alzheimer amyloid-beta peptide (abeta) intracellularly, either spontaneously or after treatment with apolipoprotein e (apoe). |
1999-04-23 |
2023-08-12 |
Not clear |
| D Bartrés-Faz, I Clement. [Apolipoproteins and cognitive deterioration]. Actas luso-espanolas de neurologia, psiquiatria y ciencias afines. vol 26. issue 6. 1999-04-22. PMID:9972590. |
apoe epsilon 4 is a well documented risk factor for late-onset alzheimer's disease (ad). |
1999-04-22 |
2023-08-12 |
human |
| H Wiebusch, J Poirier, P Sévigny, K Schapper. Further evidence for a synergistic association between APOE epsilon4 and BCHE-K in confirmed Alzheimer's disease. Human genetics. vol 104. issue 2. 1999-04-20. PMID:10190327. |
further evidence for a synergistic association between apoe epsilon4 and bche-k in confirmed alzheimer's disease. |
1999-04-20 |
2023-08-12 |
Not clear |
| T Nishimura, M Takeda, K Shinosaki, T Nishikawa, Y Nakamura, Y Yoshida, H Sasaki, H Arai, S Hirai, M Shouji, K Isse, K Tanaka, M Hamamoto, H Yamamoto, T Matsubayashi, K Nakashima, K Urakami, Y Adachi, S Nakamura, H Toji, H Yoshid. Basic and clinical studies on ApoE gene typing by line probe assay (LiPA) as a biological marker for Alzheimer's disease and related disorders: multicenter study in Japan. Methods and findings in experimental and clinical pharmacology. vol 20. issue 9. 1999-04-14. PMID:10022033. |
basic and clinical studies on apoe gene typing by line probe assay (lipa) as a biological marker for alzheimer's disease and related disorders: multicenter study in japan. |
1999-04-14 |
2023-08-12 |
Not clear |
| K Yamauchi, M Tozuka, T Nakabayashi, M Sugano, H Hidaka, Y Kondo, T Katsuyam. Apolipoprotein E in cerebrospinal fluid: relation to phenotype and plasma apolipoprotein E concentrations. Clinical chemistry. vol 45. issue 4. 1999-04-14. PMID:10102909. |
apolipoprotein (apo) e may be related to the development of alzheimer disease, but data on apoe in cerebrospinal fluid (csf) are limited. |
1999-04-14 |
2023-08-12 |
Not clear |
| C Lancashire, R Mileusnic, S P Ros. Apolipoprotein E antibodies affect the retention of passive avoidance memory in the chick. Neural plasticity. vol 6. issue 3. 1999-04-13. PMID:9920680. |
isoforms of apolipoprotein e (apoe) have been implicated as risk factors in alzheimer's disease. |
1999-04-13 |
2023-08-12 |
chicken |
| K Winkler, H Scharnagl, U Tisljar, H Hoschützky, I Friedrich, M M Hoffmann, M Hüttinger, H Wieland, W Mär. Competition of Abeta amyloid peptide and apolipoprotein E for receptor-mediated endocytosis. Journal of lipid research. vol 40. issue 3. 1999-04-13. PMID:10064733. |
the genetic polymorphism of apolipoprotein e (apoe) is associated with the age of onset and relative risk of alzheimer's disease (ad). |
1999-04-13 |
2023-08-12 |
Not clear |
| A J Slooter, P de Knijff, A Hofman, M Cruts, M M Breteler, C Van Broeckhoven, L M Havekes, C M van Duij. Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study. Neuroscience letters. vol 248. issue 1. 1999-03-30. PMID:9665654. |
the apoe*4 allele of the apolipoprotein e gene (apoe) is an important risk factor for alzheimer's disease. |
1999-03-30 |
2023-08-12 |
Not clear |
| A J Slooter, P de Knijff, A Hofman, M Cruts, M M Breteler, C Van Broeckhoven, L M Havekes, C M van Duij. Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study. Neuroscience letters. vol 248. issue 1. 1999-03-30. PMID:9665654. |
it has been suggested that levels of apolipoprotein e (apoe) in plasma are increased in alzheimer's disease. |
1999-03-30 |
2023-08-12 |
Not clear |
| A J Slooter, P de Knijff, A Hofman, M Cruts, M M Breteler, C Van Broeckhoven, L M Havekes, C M van Duij. Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study. Neuroscience letters. vol 248. issue 1. 1999-03-30. PMID:9665654. |
in this population-based study, we found that serum apoe levels were lower in alzheimer patients compared to non-demented controls (0.75 micromol/l (sd 0.35), vs. 0.83 micromol/l (sd 0.40), p < 0.05). |
1999-03-30 |
2023-08-12 |
Not clear |
| A J Slooter, P de Knijff, A Hofman, M Cruts, M M Breteler, C Van Broeckhoven, L M Havekes, C M van Duij. Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study. Neuroscience letters. vol 248. issue 1. 1999-03-30. PMID:9665654. |
this finding is in accordance with lower serum apoe levels as observed in carriers of the apoe*4 allele, who are over-represented in alzheimer's disease. |
1999-03-30 |
2023-08-12 |
Not clear |