| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Marey-Semper, M Gelman, M Lévi-Straus. The high sensitivity to rotenone of striatal dopamine uptake suggests the existence of a constitutive metabolic deficiency in dopaminergic neurons from the substantia nigra. The European journal of neuroscience. vol 5. issue 8. 1994-02-15. PMID:7904221. |
the high sensitivity to rotenone of striatal dopamine uptake suggests the existence of a constitutive metabolic deficiency in dopaminergic neurons from the substantia nigra. |
1994-02-15 |
2023-08-12 |
mouse |
| J L Hudson, C G van Horne, I Strömberg, S Brock, J Clayton, J Masserano, B J Hoffer, G A Gerhard. Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats. Brain research. vol 626. issue 1-2. 1994-02-14. PMID:8281427. |
our results indicate that an animal which has greater than a 90% depletion of dopamine in the striatum might not rotate substantially on apomorphine, without a concomitant depletion of > 50% of the da content in the corresponding substantia nigra. |
1994-02-14 |
2023-08-12 |
rat |
| G Engberg, T Kling-Petersen, H Nissbrand. GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra. Synapse (New York, N.Y.). vol 15. issue 3. 1994-02-09. PMID:8278899. |
gabab-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra. |
1994-02-09 |
2023-08-12 |
rat |
| R M Wu, C C Chiueh, A Pert, D L Murph. Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP+ in vivo. European journal of pharmacology. vol 243. issue 3. 1994-02-04. PMID:8276076. |
in addition, intranigral co-administration of l-deprenyl (4.2 nmol) with mpp+ (4.2 nmol) completely protected nigral neurons from probable oxidative injuries induced by mpp+ (4.2 nmol), as reflected by a near 50% loss of striatal dopamine ipsilateral to the side of infusion of drug into the substantia nigra. |
1994-02-04 |
2023-08-12 |
Not clear |
| K Rasmussen, J J Howbert, M E Stockto. Inhibition of A9 and A10 dopamine cells by the cholecystokinin-B antagonist LY262691: mediation through feedback pathways from forebrain sites. Synapse (New York, N.Y.). vol 15. issue 2. 1994-01-19. PMID:8259526. |
the diphenylpyrazolidinone cholecystokinin-b (cck-b) antagonist ly262691 has been shown to decrease the number of spontaneously active dopamine (da) cells in the ventral tegmental area (a10) and substantia nigra (a9) of the anesthetized rat. |
1994-01-19 |
2023-08-12 |
rat |
| J Liptrot, D Holdup, O Phillipso. 1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol depletes catecholamines in rat brain. Journal of neurochemistry. vol 61. issue 6. 1993-12-23. PMID:7504086. |
after intracerebroventricular infusion, tmiq caused reductions in dopamine concentrations in substantia nigra, striatum, hypothalamus, and dorsal raphe, and reduction in noradrenaline concentrations in locus coeruleus. |
1993-12-23 |
2023-08-12 |
rat |
| J Liptrot, D Holdup, O Phillipso. 1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol depletes catecholamines in rat brain. Journal of neurochemistry. vol 61. issue 6. 1993-12-23. PMID:7504086. |
comparisons between tmiq and mptp showed that they were approximately equipotent in depleting dopamine in the substantia nigra, hypothalamus, and dorsal raphe. |
1993-12-23 |
2023-08-12 |
rat |
| J Liptrot, D Holdup, O Phillipso. 1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol depletes catecholamines in rat brain. Journal of neurochemistry. vol 61. issue 6. 1993-12-23. PMID:7504086. |
pretreatment of animals with a combination of monoamine oxidase a and b inhibitors completely prevented the tmiq-induced reductions in dopamine concentrations in substantia nigra and hypothalamus. |
1993-12-23 |
2023-08-12 |
rat |
| J Glowinski, J C Beaujoua. [Functional properties of tachykinin receptors in the central nervous system]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 187. issue 1. 1993-12-23. PMID:8242423. |
nevertheless, biological responses of the nk2 type have been shown both in the substantia nigra and the striatum in studies on dopamine release. |
1993-12-23 |
2023-08-12 |
Not clear |
| M A Päivärinta, R J Marttila, J O Rinne, U K Rinn. Dopaminergic neurotransmission in chronic herpes simplex virus brain infection in rabbits. Journal of neural transmission. General section. vol 93. issue 3. 1993-12-21. PMID:7692884. |
dopamine (da), noradrenaline, serotonin and their metabolites were determined in the substantia nigra, caudate nucleus, putamen, nucleus accumbens, and olfactory tubercles using hplc with electrochemical detection. |
1993-12-21 |
2023-08-12 |
Not clear |
| J L Montastruc, O Rascol, J M Senar. Current status of dopamine agonists in Parkinson's disease management. Drugs. vol 46. issue 3. 1993-12-21. PMID:7693430. |
ergot derivatives (bromocriptine, lisuride, pergolide) are believed to act independently of the dying cells of the substantia nigra, acting instead directly on postsynaptic dopamine receptors in the striatum. |
1993-12-21 |
2023-08-12 |
Not clear |
| D M Yurek, S B Hipken. Intranigral injections of SCH 23390 inhibit amphetamine-induced rotational behavior. Brain research. vol 623. issue 1. 1993-12-21. PMID:8221093. |
rats were given unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway and permanent indwelling cannula were surgically implanted into the non-lesioned side of the brain; cannula were used for direct injections of dopamine antagonists into the pars reticulata region of the non-lesioned substantia nigra. |
1993-12-21 |
2023-08-12 |
rat |
| J Dymeck. [Neurotransplantations: experimental studies]. Neurologia i neurochirurgia polska. vol 27. issue 3. 1993-12-13. PMID:8232738. |
before the intracerebral transplantations of adrenal medulla and fetal substantia nigra in parkinsonian patients were introduced to restore the dopamine deficit, many intensive experimental studies were performed during the last decades. |
1993-12-13 |
2023-08-12 |
Not clear |
| P R Paetsch, A J Greenshaw, A V Juori. Phenylalanine in the caudate nucleus of dopamine depleted rats. Neurochemical research. vol 18. issue 9. 1993-12-07. PMID:7694165. |
dopamine depleting lesions of the substantia nigra result in a reduction of the striatal accumulation of 2-phenylethylamine following monoamine oxidase inhibition. |
1993-12-07 |
2023-08-12 |
rat |
| P R Paetsch, A J Greenshaw, A V Juori. Phenylalanine in the caudate nucleus of dopamine depleted rats. Neurochemical research. vol 18. issue 9. 1993-12-07. PMID:7694165. |
the present experiments assessed the effects of dopamine depletion induced by 6-ohda (7 days following 8 micrograms/4 microliters unilateral substantia nigra injection) on striatal concentrations of phenylalanine, dopamine, 5-hydroxytryptamine and their metabolites. |
1993-12-07 |
2023-08-12 |
rat |
| W J McBride, E Chernet, W Dyr, L Lumeng, T K L. Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats. Alcohol (Fayetteville, N.Y.). vol 10. issue 5. 1993-12-07. PMID:8216885. |
the densities of dopamine d2 recognition sites labelled with [3h]sulpiride were determined in the caudate-putamen, nucleus accumbens (medial and lateral portions), olfactory tubercle, substantia nigra (pars reticulata and pars compacta), and ventral tegmental area (vta) of alcohol-naive, selectively bred p (n = 7) and np (n = 7) rats using quantitative autoradiography. |
1993-12-07 |
2023-08-12 |
rat |
| H Nagasawa, K Kogure, T Id. Simultaneous demonstration of neurotransmitter and receptor systems of the rat brain using in vivo double autoradiography. The Tohoku journal of experimental medicine. vol 169. issue 1. 1993-11-17. PMID:8105560. |
the [3h]ym-09151-2 was also found to be accumulated in the substantia nigra which is known to correspond with the distribution of dopamine d2 receptors. |
1993-11-17 |
2023-08-12 |
rat |
| A Castaño, J Cano, A Machad. Low selenium diet affects monoamine turnover differentially in substantia nigra and striatum. Journal of neurochemistry. vol 61. issue 4. 1993-10-21. PMID:8376988. |
turnover of dopamine, noradrenaline, serotonin, and their metabolites has been measured in striatum and substantia nigra of adult female rats that were fed control or selenium-deficient diets for 15 days. |
1993-10-21 |
2023-08-12 |
rat |
| A Castaño, J Cano, A Machad. Low selenium diet affects monoamine turnover differentially in substantia nigra and striatum. Journal of neurochemistry. vol 61. issue 4. 1993-10-21. PMID:8376988. |
the most striking result was the increase of dopamine turnover (63%) and 3-methoxytyramine turnover (55%) in substantia nigra between control and experimental animals. |
1993-10-21 |
2023-08-12 |
rat |
| J Grenhoff, M Nisell, S Ferré, G Aston-Jones, T H Svensso. Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat. Journal of neural transmission. General section. vol 93. issue 1. 1993-10-20. PMID:8373553. |
electrical stimulation techniques were employed in the chloral hydrate anaesthetized male rat to evaluate if the pontine noradrenergic nucleus locus coeruleus can influence the activity of midbrain dopamine neurons in the ventral tegmental area and zona compacta, substantia nigra. |
1993-10-20 |
2023-08-12 |
rat |