| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Magal, P Burnham, S Varon, J C Loui. Convergent regulation by ciliary neurotrophic factor and dopamine of tyrosine hydroxylase expression in cultures of rat substantia nigra. Neuroscience. vol 52. issue 4. 1993-04-15. PMID:8095711. |
ciliary neurotrophic factor and dopamine were found to enhance the expression of tyrosine hydroxylase immunoreactivity in cultured neurons from the substantia nigra of 16-day-old rat fetuses. |
1993-04-15 |
2023-08-12 |
rat |
| V M Pickel, J Chan, S R Sesac. Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra. Brain research. vol 602. issue 2. 1993-04-13. PMID:8095430. |
cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra. |
1993-04-13 |
2023-08-12 |
mouse |
| V M Pickel, J Chan, S R Sesac. Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra. Brain research. vol 602. issue 2. 1993-04-13. PMID:8095430. |
dynorphin and other kappa opioid agonists are thought to elicit aversive actions and changes in motor activity through direct or indirect modulation of dopamine neurons in ventral tegmental area (vta) and substantia nigra (sn), respectively. |
1993-04-13 |
2023-08-12 |
mouse |
| J P Heaton, S J Varri. Effects of streptozotocin-induced diabetes on dopaminergic functioning in the rat: analysis of yawning behavior. Pharmacology, biochemistry, and behavior. vol 44. issue 3. 1993-04-12. PMID:8451264. |
dopamine turnover in the substantia nigra of diabetic rats has been shown to be decreased following administration of amphetamine or apomorphine (17,21). |
1993-04-12 |
2023-08-12 |
rat |
| A Elverfors, J Jonason, G Jonason, G Leonsson, H Nissbrand. Determination of release of endogenous dopamine from superfused substantia nigra slices. Journal of neuroscience methods. vol 45. issue 3. 1993-04-09. PMID:1363484. |
determination of release of endogenous dopamine from superfused substantia nigra slices. |
1993-04-09 |
2023-08-11 |
Not clear |
| A Elverfors, J Jonason, G Jonason, G Leonsson, H Nissbrand. Determination of release of endogenous dopamine from superfused substantia nigra slices. Journal of neuroscience methods. vol 45. issue 3. 1993-04-09. PMID:1363484. |
dopamine (da) is synthesized and released not only from the terminals of the nigrostriatal dopaminergic neuronal pathway but also from cell bodies and dendrites in the substantia nigra (sn). |
1993-04-09 |
2023-08-11 |
Not clear |
| J Fornaguera, R K Schwarting, F Boix, J P Husto. Behavioral indices of moderate nigro-striatal 6-hydroxydopamine lesion: a preclinical Parkinson's model. Synapse (New York, N.Y.). vol 13. issue 2. 1993-04-02. PMID:7680495. |
asymmetries in turning and scanning were investigated in rats with different degrees of neostriatal dopamine depletion after unilateral injections of 6-hydroxydopamine into the substantia nigra. |
1993-04-02 |
2023-08-12 |
rat |
| L T Meltzer, C L Christoffersen, K A Serpa, A Razmpou. Comparison of the effects of the cholecystokinin-B receptor antagonist, PD 134308, and the cholecystokinin-A receptor antagonist, L-364,718, on dopamine neuronal activity in the substantia nigra and ventral tegmental area. Synapse (New York, N.Y.). vol 13. issue 2. 1993-04-02. PMID:8446920. |
comparison of the effects of the cholecystokinin-b receptor antagonist, pd 134308, and the cholecystokinin-a receptor antagonist, l-364,718, on dopamine neuronal activity in the substantia nigra and ventral tegmental area. |
1993-04-02 |
2023-08-12 |
rat |
| E Ronken, F L Van Muiswinkel, A H Mulder, A N Schoffelmee. Opioid receptor-mediated inhibition of evoked catecholamine release from cultured neurons of rat ventral mesencephalon and locus coeruleus. European journal of pharmacology. vol 230. issue 3. 1993-04-01. PMID:8095023. |
the effects of selective opioid agonists on the evoked release of [3h]dopamine and [3h]noradrenaline were studied in cultured dopaminergic neurons of the ventral mesencephalon (containing the substantia nigra and ventral tegmental area) and in cultured neurons of the noradrenergic locus coeruleus, respectively. |
1993-04-01 |
2023-08-12 |
human |
| S N Schiffmann, J J Vanderhaeghe. Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 3. 1993-03-30. PMID:7680065. |
the a2a receptor is mainly expressed by neurons projecting to the globus pallidus and expressing also the dopamine d2 receptor and enkephalin, but very sparsely by neurons projecting to the substantia nigra that express the dopamine d1 receptor and substance p. we have further examined the regulatory effect of the a2 receptors on striatal gene expression using in situ hybridization histochemistry and quantitative autoradiography. |
1993-03-30 |
2023-08-12 |
rat |
| C D Blaha, P Win. Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmental nucleus-lesioned rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 3. 1993-03-30. PMID:8441002. |
modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmental nucleus-lesioned rats. |
1993-03-30 |
2023-08-12 |
rat |
| E Molina-Holgado, K M Dewar, L Grondin, N M van Gelder, T A Reade. Amino acid levels and gamma-aminobutyric acidA receptors in rat neostriatum, cortex, and thalamus after neonatal 6-hydroxydopamine lesion. Journal of neurochemistry. vol 60. issue 3. 1993-03-24. PMID:8382266. |
dopamine fibers arising from the substantia nigra represent a major input to the neostriatum where, besides their classic neurotransmitter role, they are seemingly involved in the regulation of amino acid neurotransmitter release. |
1993-03-24 |
2023-08-12 |
rat |
| K Tsou, J A Girault, P Greengar. Dopamine D1 agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra. Journal of neurochemistry. vol 60. issue 3. 1993-03-24. PMID:8436957. |
dopamine d1 agonist skf 38393 increases the state of phosphorylation of arpp-21 in substantia nigra. |
1993-03-24 |
2023-08-12 |
Not clear |
| K Takada, T Murai, T Kanayama, N Koshikaw. Effects of midazolam and flunitrazepam on the release of dopamine from rat striatum measured by in vivo microdialysis. British journal of anaesthesia. vol 70. issue 2. 1993-03-23. PMID:8435263. |
flunitrazepam 10 mumol litre-1 also decreased striatal dopamine release when infused through a dialysis probe placed into the striatum, but it failed to affect striatal dopamine release when infused into the ipsilateral substantia nigra. |
1993-03-23 |
2023-08-12 |
rat |
| P B Silverma. Sensitization, response fluctuation and long-term effect of SKF-82958 and bromocriptine in the hemi-parkinsonian rat. European journal of pharmacology. vol 229. issue 2-3. 1993-03-02. PMID:1362705. |
rats with a unilateral 6-hydroxydopamine lesion of substantia nigra were treated with the dopamine agonists skf-82958 (d1 receptor selective) or bromocriptine (d2 receptor-selective) and their circling response recorded. |
1993-03-02 |
2023-08-11 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
using microdialysis in the ventral tegmental area and medial substantia nigra, the effect of repeated cocaine was examined on the extracellular levels of dopamine. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
in separate animals, the basal concentration of dopamine in the ventral tegmental area/medial substantia nigra was measured by determining the concentration of dopamine at which no net flux occurred across the dialysis membrane in vivo. |
1993-02-24 |
2023-08-12 |
rat |
| K Rasmussen, J F Czachura, M E Stockton, J J Howber. Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 264. issue 1. 1993-02-23. PMID:8423546. |
the diphenylpyrazolidinone cholecystokinin (cck)-b antagonist ly262691 has recently been demonstrated to decrease the number of spontaneously active dopamine (da) cells in the ventral tegmental area (a10) and substantia nigra (a9) of the anesthetized rat. |
1993-02-23 |
2023-08-12 |
rat |
| G Tunniclif. Significance of gamma-hydroxybutyric acid in the brain. General pharmacology. vol 23. issue 6. 1993-02-19. PMID:1487112. |
ghb might play a role as a neurotransmitter, particularly being involved in influencing dopamine release in the substantia nigra. |
1993-02-19 |
2023-08-11 |
Not clear |
| B H Westerink, M Santiago, J B De Vrie. In vivo evidence for a concordant response of terminal and dendritic dopamine release during intranigral infusion of drugs. Naunyn-Schmiedeberg's archives of pharmacology. vol 346. issue 6. 1993-02-18. PMID:1362452. |
in the present study we have administered prototypical drugs of 5 different receptors (d-2, gaba-a, gaba-b, nmda, kainate) to the substantia nigra by infusion via a microdialysis probe, whereas the release of dopamine and 3,4-dihydroxyphenylacetic acid (dopac) were recorded both in the substantia nigra and (by a second microdialysis probe) in the ipsilateral striatum. |
1993-02-18 |
2023-08-11 |
Not clear |