| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Marchi, G Volpe, A Augliera, A Codignola, G Lunardi, M Raiter. Cholinergic modulation of dopamine release in corpus striatum and substantia nigra of the rat. Neurochemistry international. vol 20 Suppl. 1995-01-30. PMID:1365441. |
cholinergic modulation of dopamine release in corpus striatum and substantia nigra of the rat. |
1995-01-30 |
2023-08-11 |
rat |
| A Zuddas, F Vaglini, F Fornai, G U Corsin. Selective lesion of the nigrostriatal dopaminergic pathway by MPTP and acetaldehyde or diethyldithiocarbamate. Neurochemistry international. vol 20 Suppl. 1995-01-30. PMID:1365444. |
here we show that these drugs enhance the depletion of dopamine in the striatum and markedly increase mptp-induced death of da neurons in the substantia nigra. |
1995-01-30 |
2023-08-11 |
mouse |
| M L Pucak, A A Grac. Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996424. |
systemic administration of dopamine antagonists increases the activity of some dopamine neurons in the substantia nigra, and this effect is thought to occur through two potential mechanisms: 1) local blockade of dopamine acting at somatodendritic autoreceptors or 2) blockade of receptors on postsynaptic targets in the striatum, resulting in long-loop feedback modulation. |
1995-01-17 |
2023-08-12 |
rat |
| M L Pucak, A A Grac. Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996424. |
thus, dopamine antagonists most likely increase dopamine cell firing rate by blockade of somatodendritic autoreceptors, suggesting that the basal activity of the cells is dependent in part on dendritically released dopamine within the substantia nigra. |
1995-01-17 |
2023-08-12 |
rat |
| K X Huang, J R Walter. Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996456. |
induces a small (averaging 20% above base line) increase in firing rates of snpr neurons in normal rats and significantly inhibits snpr single unit activity in rats studied 6 to 26 weeks after 6-hydroxydopamine (6-ohda)-induced substantia nigra dopamine cell lesion. |
1995-01-17 |
2023-08-12 |
rat |
| Y F Tsai, H W Tsai, M Y Ta. Comparison of brain dopamine depletion induced by low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in young and aged rats. Neuroscience research. vol 20. issue 1. 1995-01-05. PMID:7984338. |
effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) on dopamine levels in the striatum (st), substantia nigra (sn), olfactory tubercle (ot), ventral tegmental area (vta) and nucleus accumbens (na) were studied in young (1 month) and old (21 months) male long-evans rats. |
1995-01-05 |
2023-08-12 |
rat |
| B Hitzemann, K Dains, S Kanes, R Hitzeman. Further studies on the relationship between dopamine cell density and haloperidol-induced catalepsy. The Journal of pharmacology and experimental therapeutics. vol 271. issue 2. 1994-12-29. PMID:7965819. |
previous data have suggested that the genetic variability in the sensitivity to haloperidol-induced catalepsy is associated with the number of dopamine neurons in the substantia nigra zona compacta (snzc). |
1994-12-29 |
2023-08-12 |
mouse |
| A Flamez, J P de Backer, N Wilczak, G Vauquelin, J de Keyse. [3H]Clozapine is not a suitable radioligand for the labelling of D4 dopamine receptors in postmortem human brain. Neuroscience letters. vol 175. issue 1-2. 1994-12-29. PMID:7970202. |
we found that, in membranes of postmortem human striatum, amygdala, frontal cortex and substantia nigra, neither dopamine nor the dopamine agonist apomorphine displaced the binding of [3h]clozapine (5-20 nm). |
1994-12-29 |
2023-08-12 |
human |
| R J Beninger, A M Colton, J L Ingles, K Jhamandas, R J Boegma. Picolinic acid blocks the neurotoxic but not the neuroexcitant properties of quinolinic acid in the rat brain: evidence from turning behaviour and tyrosine hydroxylase immunohistochemistry. Neuroscience. vol 61. issue 3. 1994-12-27. PMID:7969932. |
and apomorphine (0.5 mg/kg, s.c.), respectively, consistent with unilateral loss of dopamine cells in the substantia nigra. |
1994-12-27 |
2023-08-12 |
rat |
| B Landwehrmeyer, J M Palacio. Alterations of neurotransmitter receptors and neurotransmitter transporters in progressive supranuclear palsy. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7525868. |
densities of dopamine uptake sites and neurotensin receptors were significantly reduced in striatum and substantia nigra consistent with a localization of these binding sites on degenerating dopaminergic nigrostriatal projection neurons. |
1994-12-22 |
2023-08-12 |
Not clear |
| O Hornykiewicz, K Shanna. Brain monoamines in progressive supranuclear palsy--comparison with idiopathic Parkinson's disease. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964689. |
like idiopathic parkinson's disease (ipd), progressive supranuclear palsy (psp) is characterized, inter alia, by a pronounced non-overlapping loss of dopamine (da) in caudate, putamen and substantia nigra. |
1994-12-22 |
2023-08-12 |
Not clear |
| G A Hicks, A L Hudson, G Henderso. Localization of high affinity [3H]glibenclamide binding sites within the substantia nigra zona reticulata of the rat brain. Neuroscience. vol 61. issue 2. 1994-12-08. PMID:7969909. |
autoradiography was performed on coronal sections of midbrain with [3h]glibenclamide, [3h]ym-09151-2 (dopamine d2 receptor antagonist) and [3h]sch 23390 (dopamine d1 receptor antagonist) at three rostrocaudal levels of the substantia nigra. |
1994-12-08 |
2023-08-12 |
rat |
| E J Mufson, J S Kroin, T Sobreviela, M A Burke, J H Kordower, R D Penn, J A Mille. Intrastriatal infusions of brain-derived neurotrophic factor: retrograde transport and colocalization with dopamine containing substantia nigra neurons in rat. Experimental neurology. vol 129. issue 1. 1994-11-16. PMID:7523178. |
intrastriatal infusions of brain-derived neurotrophic factor: retrograde transport and colocalization with dopamine containing substantia nigra neurons in rat. |
1994-11-16 |
2023-08-12 |
human |
| K Chergui, H Akaoka, P J Charléty, C F Saunier, M Buda, G Chouve. Subthalamic nucleus modulates burst firing of nigral dopamine neurones via NMDA receptors. Neuroreport. vol 5. issue 10. 1994-11-10. PMID:7919161. |
the role of the subthalamic nucleus in the burst firing of dopamine neurones of the substantia nigra was investigated using extracellular single unit recordings combined with pressure or iontophoretic micro-injections in anaesthetized rats. |
1994-11-10 |
2023-08-12 |
rat |
| K Chergui, H Akaoka, P J Charléty, C F Saunier, M Buda, G Chouve. Subthalamic nucleus modulates burst firing of nigral dopamine neurones via NMDA receptors. Neuroreport. vol 5. issue 10. 1994-11-10. PMID:7919161. |
these data suggest that the subthalamic nucleus promotes burst discharge in a subpopulation of substantia nigra dopamine neurones via nmda receptors. |
1994-11-10 |
2023-08-12 |
rat |
| B Bowery, L A Rothwell, G R Seabroo. Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area. British journal of pharmacology. vol 112. issue 3. 1994-11-09. PMID:7921615. |
dopamine receptors, caused a slight but significant shift in the concentration-effect curve to quinpirole with an estimated pka of 6.97 +/- 0.13(n =4) in the substantia nigra and pka of 7.12 +/- 0.22 (n =4) in the ventral tegmental area.5. |
1994-11-09 |
2023-08-12 |
rat |
| B Bowery, L A Rothwell, G R Seabroo. Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area. British journal of pharmacology. vol 112. issue 3. 1994-11-09. PMID:7921615. |
comparison of these data with the binding affinity for cloned dopamine receptors demonstrates that the responses to quinpirole on dopaminergic neurones in both the a9 (substantia nigra) and a10(ventral tegmental area) brain areas are consistent with the activation of predominantly d2, and not d3 or d4 dopamine receptors. |
1994-11-09 |
2023-08-12 |
rat |
| K R Isaacs, D M Jacobowit. Mapping of the colocalization of calretinin and tyrosine hydroxylase in the rat substantia nigra and ventral tegmental area. Experimental brain research. vol 99. issue 1. 1994-11-02. PMID:7925794. |
the distribution of calretinin (cr), a calcium binding protein, was compared with that of tyrosine hydroxylase (th), the rate-limiting enzyme in the synthesis of dopamine, throughout the rostrocaudal extent of the rat substantia nigra (sn) and ventral tegmental area (vta). |
1994-11-02 |
2023-08-12 |
rat |
| D G Cole, L A Kobierski, C Konradi, S E Hyma. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 20. 1994-10-27. PMID:7937819. |
increased striatal c-fos expression ipsilateral to a unilateral lesion of the substantia nigra in rats treated with appropriate dopamine agonists provides a cellular marker of d1 receptor supersensitivity. |
1994-10-27 |
2023-08-12 |
rat |
| M Ia Voloshin, E P Lukhanina, B P Kolomiet. [The effect of a blockade of the dopamine D2 receptors in the cat neostriatum on the neuronal background activity and reactions of the reticular portion of the substantia nigra related to saccadic eye movements]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 80. issue 1. 1994-10-26. PMID:7522763. |
[the effect of a blockade of the dopamine d2 receptors in the cat neostriatum on the neuronal background activity and reactions of the reticular portion of the substantia nigra related to saccadic eye movements]. |
1994-10-26 |
2023-08-12 |
cat |