| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Beninger, A M Colton, J L Ingles, K Jhamandas, R J Boegma. Picolinic acid blocks the neurotoxic but not the neuroexcitant properties of quinolinic acid in the rat brain: evidence from turning behaviour and tyrosine hydroxylase immunohistochemistry. Neuroscience. vol 61. issue 3. 1994-12-27. PMID:7969932. |
and apomorphine (0.5 mg/kg, s.c.), respectively, consistent with unilateral loss of dopamine cells in the substantia nigra. |
1994-12-27 |
2023-08-12 |
rat |
| B Landwehrmeyer, J M Palacio. Alterations of neurotransmitter receptors and neurotransmitter transporters in progressive supranuclear palsy. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7525868. |
densities of dopamine uptake sites and neurotensin receptors were significantly reduced in striatum and substantia nigra consistent with a localization of these binding sites on degenerating dopaminergic nigrostriatal projection neurons. |
1994-12-22 |
2023-08-12 |
Not clear |
| O Hornykiewicz, K Shanna. Brain monoamines in progressive supranuclear palsy--comparison with idiopathic Parkinson's disease. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964689. |
like idiopathic parkinson's disease (ipd), progressive supranuclear palsy (psp) is characterized, inter alia, by a pronounced non-overlapping loss of dopamine (da) in caudate, putamen and substantia nigra. |
1994-12-22 |
2023-08-12 |
Not clear |
| G A Hicks, A L Hudson, G Henderso. Localization of high affinity [3H]glibenclamide binding sites within the substantia nigra zona reticulata of the rat brain. Neuroscience. vol 61. issue 2. 1994-12-08. PMID:7969909. |
autoradiography was performed on coronal sections of midbrain with [3h]glibenclamide, [3h]ym-09151-2 (dopamine d2 receptor antagonist) and [3h]sch 23390 (dopamine d1 receptor antagonist) at three rostrocaudal levels of the substantia nigra. |
1994-12-08 |
2023-08-12 |
rat |
| E J Mufson, J S Kroin, T Sobreviela, M A Burke, J H Kordower, R D Penn, J A Mille. Intrastriatal infusions of brain-derived neurotrophic factor: retrograde transport and colocalization with dopamine containing substantia nigra neurons in rat. Experimental neurology. vol 129. issue 1. 1994-11-16. PMID:7523178. |
intrastriatal infusions of brain-derived neurotrophic factor: retrograde transport and colocalization with dopamine containing substantia nigra neurons in rat. |
1994-11-16 |
2023-08-12 |
human |
| K Chergui, H Akaoka, P J Charléty, C F Saunier, M Buda, G Chouve. Subthalamic nucleus modulates burst firing of nigral dopamine neurones via NMDA receptors. Neuroreport. vol 5. issue 10. 1994-11-10. PMID:7919161. |
the role of the subthalamic nucleus in the burst firing of dopamine neurones of the substantia nigra was investigated using extracellular single unit recordings combined with pressure or iontophoretic micro-injections in anaesthetized rats. |
1994-11-10 |
2023-08-12 |
rat |
| K Chergui, H Akaoka, P J Charléty, C F Saunier, M Buda, G Chouve. Subthalamic nucleus modulates burst firing of nigral dopamine neurones via NMDA receptors. Neuroreport. vol 5. issue 10. 1994-11-10. PMID:7919161. |
these data suggest that the subthalamic nucleus promotes burst discharge in a subpopulation of substantia nigra dopamine neurones via nmda receptors. |
1994-11-10 |
2023-08-12 |
rat |
| B Bowery, L A Rothwell, G R Seabroo. Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area. British journal of pharmacology. vol 112. issue 3. 1994-11-09. PMID:7921615. |
dopamine receptors, caused a slight but significant shift in the concentration-effect curve to quinpirole with an estimated pka of 6.97 +/- 0.13(n =4) in the substantia nigra and pka of 7.12 +/- 0.22 (n =4) in the ventral tegmental area.5. |
1994-11-09 |
2023-08-12 |
rat |
| B Bowery, L A Rothwell, G R Seabroo. Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area. British journal of pharmacology. vol 112. issue 3. 1994-11-09. PMID:7921615. |
comparison of these data with the binding affinity for cloned dopamine receptors demonstrates that the responses to quinpirole on dopaminergic neurones in both the a9 (substantia nigra) and a10(ventral tegmental area) brain areas are consistent with the activation of predominantly d2, and not d3 or d4 dopamine receptors. |
1994-11-09 |
2023-08-12 |
rat |
| K R Isaacs, D M Jacobowit. Mapping of the colocalization of calretinin and tyrosine hydroxylase in the rat substantia nigra and ventral tegmental area. Experimental brain research. vol 99. issue 1. 1994-11-02. PMID:7925794. |
the distribution of calretinin (cr), a calcium binding protein, was compared with that of tyrosine hydroxylase (th), the rate-limiting enzyme in the synthesis of dopamine, throughout the rostrocaudal extent of the rat substantia nigra (sn) and ventral tegmental area (vta). |
1994-11-02 |
2023-08-12 |
rat |
| D G Cole, L A Kobierski, C Konradi, S E Hyma. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 20. 1994-10-27. PMID:7937819. |
increased striatal c-fos expression ipsilateral to a unilateral lesion of the substantia nigra in rats treated with appropriate dopamine agonists provides a cellular marker of d1 receptor supersensitivity. |
1994-10-27 |
2023-08-12 |
rat |
| M Ia Voloshin, E P Lukhanina, B P Kolomiet. [The effect of a blockade of the dopamine D2 receptors in the cat neostriatum on the neuronal background activity and reactions of the reticular portion of the substantia nigra related to saccadic eye movements]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 80. issue 1. 1994-10-26. PMID:7522763. |
[the effect of a blockade of the dopamine d2 receptors in the cat neostriatum on the neuronal background activity and reactions of the reticular portion of the substantia nigra related to saccadic eye movements]. |
1994-10-26 |
2023-08-12 |
cat |
| L K Nisenbaum, S T Kitai, W R Crowley, C R Gerfe. Temporal dissociation between changes in striatal enkephalin and substance P messenger RNAs following striatal dopamine depletion. Neuroscience. vol 60. issue 4. 1994-10-24. PMID:7523989. |
changes in the levels of enkephalin and substance p messenger rna expression were examined in the striatum following dopamine depletion resulting from unilateral injection of 6-hydroxydopamine into the substantia nigra. |
1994-10-24 |
2023-08-12 |
Not clear |
| R Daniels, G F Harding, S J Anderso. Effect of dopamine and acetylcholine on the visual evoked potential. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 16. issue 2-3. 1994-10-18. PMID:7916338. |
dopamine is a neurotransmitter known to be present in the retina of primates and is found to be severely depleted in the substantia nigra of patients with parkinson's disease. |
1994-10-18 |
2023-08-12 |
Not clear |
| R Y Shen, C A Altar, L A Chiod. Brain-derived neurotrophic factor increases the electrical activity of pars compacta dopamine neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:8090745. |
chronic infusions of brain-derived neurotrophic factor (bdnf) immediately above the substantia nigra augment spontaneous locomotion, rotational behavior, and striatal dopamine (da) turnover, indicating that bdnf increases functions of the nigrostriatal da system. |
1994-10-14 |
2023-08-12 |
Not clear |
| D J Clarke, A P Payn. Neuroanatomical characterization of a new mutant rat with dopamine depletion in the substantia nigra. The European journal of neuroscience. vol 6. issue 5. 1994-10-03. PMID:7915606. |
neuroanatomical characterization of a new mutant rat with dopamine depletion in the substantia nigra. |
1994-10-03 |
2023-08-12 |
rat |
| M G Rosales, G Flores, S Hernández, D Martínez-Fong, J Aceve. Activation of subthalamic neurons produces NMDA receptor-mediated dendritic dopamine release in substantia nigra pars reticulata: a microdialysis study in the rat. Brain research. vol 645. issue 1-2. 1994-09-21. PMID:8062095. |
here we have studied whether the activation of the subthalamic neurons induces the release of dopamine (da) from dopaminergic dendrites in the pars reticulata of the substantia nigra. |
1994-09-21 |
2023-08-12 |
rat |
| D M Bronstein, H Ye, K R Pennypacker, P M Hudson, J S Hon. Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat. Brain research. Molecular brain research. vol 23. issue 3. 1994-09-12. PMID:7914658. |
d1 dopamine (da) receptor agonists induce the expression of the opioid peptide dynorphin (dyn) in the striatum, an effect accentuated several fold by removing the dopaminergic innervation to the striatum (e.g., by lesioning the da cell bodies in the substantia nigra [sn]). |
1994-09-12 |
2023-08-12 |
rat |
| M H Mark, J I Sage, D W Dickson, R E Heikkila, L Manzino, K O Schwarz, R C Duvoisi. Meige syndrome in the spectrum of Lewy body disease. Neurology. vol 44. issue 8. 1994-09-12. PMID:8058144. |
neurochemical analysis of postmortem brain tissue showed evidence for decreased dopamine turnover in the substantia nigra, striatum, and nucleus accumbens. |
1994-09-12 |
2023-08-12 |
Not clear |
| D Nakahara, W Maruyama, H Hashiguti, M Nao. Characterization of the in vivo action of (R)-salsolinol, an endogenous metabolite of alcohol, on serotonin and dopamine metabolism: a microdialysis study. Brain research. vol 644. issue 2. 1994-09-08. PMID:8050034. |
using a microdialysis-hplc technique in conscious rats, we examined the action of (r)-1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (r)-salsolinol (r-sal), a possible endogenous metabolite of alcohol, on serotonin (5-ht) and dopamine (da) metabolism in four regions of the brain: the striatum, the substantia nigra, the hippocampus and the hypothalamus. |
1994-09-08 |
2023-08-12 |
rat |