| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T E Robinson, M Noordhoorn, E M Chan, Z Mocsary, D M Camp, I Q Whisha. Relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6-OHDA lesion of the substantia nigra. Synapse (New York, N.Y.). vol 17. issue 1. 1994-08-23. PMID:8042143. |
relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6-ohda lesion of the substantia nigra. |
1994-08-23 |
2023-08-12 |
rat |
| S Chen, X Zhou, D Xu, Q Tang, X X. Parkinsonism induced with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in cats: behavioral, biochemical and pathological studies. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. vol 8. issue 4. 1994-08-12. PMID:8032069. |
reduction of the concentration of dopamine and its metabolites was determined in the substantia nigra and putamen by high performance liquid chromatography (hplc). |
1994-08-12 |
2023-08-12 |
cat |
| L P Martin, B L Waszcza. D1 agonist-induced excitation of substantia nigra pars reticulata neurons: mediation by D1 receptors on striatonigral terminals via a pertussis toxin-sensitive coupling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 7. 1994-08-11. PMID:7913124. |
iontophoresis of dopamine or the d1 agonist skf 38393 has been shown to elicit current-dependent increases in the firing of rat substantia nigra pars reticulata neurons, suggesting a discrete physiological role for the d1 dopamine receptor population in the substantia nigra. |
1994-08-11 |
2023-08-12 |
rat |
| J H Ryu, K Yanai, R Iwata, T Ido, T Watanab. Heterogeneous distributions of histamine H3, dopamine D1 and D2 receptors in rat brain. Neuroreport. vol 5. issue 5. 1994-08-08. PMID:8025257. |
this treatment resulted in similar decreases in histamine h3 and dopamine d1 receptor binding sites in the striatum and ipsilateral substantia nigra. |
1994-08-08 |
2023-08-12 |
rat |
| K D Keegan, G N Woodruff, R D Pinnoc. The pharmacology of neurotensin analogues on neurones in the rat substantia nigra, pars compacta in vitro. European journal of pharmacology. vol 253. issue 1-2. 1994-07-26. PMID:8013539. |
the effects of neurotensin and neurotensin analogues on dopamine neurones were studied in an in vitro slice preparation of rat substantia nigra, pars compacta using extracellular and intracellular recording techniques. |
1994-07-26 |
2023-08-12 |
rat |
| H Sauer, W H Oerte. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience. vol 59. issue 2. 1994-07-21. PMID:7516500. |
in order to develop a rodent model displaying a progressive degeneration of the dopamine neurons of the substantia nigra, we bilaterally injected the tracer substance fluorogold into the terminal field of the nigrostriatal projection, i.e. |
1994-07-21 |
2023-08-12 |
rat |
| O Stork, T Hashimoto, K Obat. Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience research. vol 19. issue 1. 1994-07-20. PMID:7911985. |
the number of th-positive cells was increased for both ish and imhc 8 h after a single administration of benzodiazepine diazepam, which facilitates gabaa-receptor-mediated transmission and reduces dopamine release in the substantia nigra (sn). |
1994-07-20 |
2023-08-12 |
rat |
| O Stork, T Hashimoto, K Obat. Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience research. vol 19. issue 1. 1994-07-20. PMID:7911985. |
in conclusion, gabaergic substances will activate th gene expression in snr neurons (1) through decreasing spontaneous somato-dendritic dopamine release in the substantia nigra and/or (2) by increasing the activity of these neurons. |
1994-07-20 |
2023-08-12 |
rat |
| A C Linthorst, P L van Giersbergen, M Gras, D H Versteeg, W de Jon. The nigrostriatal dopamine system: role in the development of hypertension in spontaneously hypertensive rats. Brain research. vol 639. issue 2. 1994-07-13. PMID:8205480. |
the effects of lesions in the pars compacta of the substantia nigra of 4-week-old spontaneously hypertensive rats (shr) and normotensive wistar-kyoto rats (wky) were studied on (a) changes in blood pressure during a period of 6 weeks following lesioning, and (b) dopamine and metabolite concentrations in the caudate nucleus and (c) the in vitro release of [3h]dopamine from caudate nucleus slices 6 weeks after the lesioning. |
1994-07-13 |
2023-08-12 |
rat |
| H Q Wu, R Schwarcz, P D Shepar. Excitatory amino acid-induced excitation of dopamine-containing neurons in the rat substantia nigra: modulation by kynurenic acid. Synapse (New York, N.Y.). vol 16. issue 3. 1994-06-27. PMID:7515199. |
kynurenic acid (kyna), an endogenous antagonist of ionotropic excitatory amino acid (eaa) receptors, was tested for its ability to modulate n-methyl-d-aspartate (nmda)- and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa)-induced excitation of dopamine (da)-containing neurons in the zona compacta of the rat substantia nigra (snc). |
1994-06-27 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. |
1994-06-23 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
an aberrant network of dopamine axons was found to pervade the rat substantia nigra following neonatal destruction of its dopamine nerve cell bodies and dendrites by cerebroventricular administration of 6-hydroxydopamine. |
1994-06-23 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
in rats 6-hydroxydopamine-lesioned at postnatal day 3 (p3) and examined at p7, p10, p15, p30 or later, some dopamine fibers were already present in the substantia nigra at p7; their number increased sharply until p15 and only slightly thereafter, assuming a topographic distribution reminiscent of the missing dopamine nerve cell bodies and dendrites. |
1994-06-23 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
a similar growth of dopamine fibers took place in the substantia nigra after lesions made at p6, p9 and p12, but was less pronounced after lesion at p15 and absent after lesion at p21 or later. |
1994-06-23 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
it will be of particular interest to investigate the functional consequences of the dopamine neoinnervation in the substantia nigra, where an eventual axonal release might thus be replacing the normal somatodendritic release of this amine. |
1994-06-23 |
2023-08-12 |
rat |
| C Gauchy, M Desban, J Glowinski, M L Keme. NMDA regulation of dopamine release from proximal and distal dendrites in the cat substantia nigra. Brain research. vol 635. issue 1-2. 1994-06-09. PMID:8173961. |
nmda regulation of dopamine release from proximal and distal dendrites in the cat substantia nigra. |
1994-06-09 |
2023-08-12 |
cat |
| C Gauchy, M Desban, J Glowinski, M L Keme. NMDA regulation of dopamine release from proximal and distal dendrites in the cat substantia nigra. Brain research. vol 635. issue 1-2. 1994-06-09. PMID:8173961. |
the nmda regulation of the dendritic release of [3h]dopamine ([3h]da) synthesized from [3h]tyrosine was investigated in vitro using a microsuperfusion procedure in the pars compacta (snc) and the pars reticulata (snr) of the cat substantia nigra. |
1994-06-09 |
2023-08-12 |
cat |
| B H Westerink, P de Boer, M Santiago, J B De Vrie. Do nerve terminals and cell bodies of nigrostriatal dopaminergic neurons of the rat contain similar receptors? Neuroscience letters. vol 167. issue 1-2. 1994-06-06. PMID:8177506. |
in separate experiments the same drugs were infused into the substantia nigra and effects on dendritic release of dopamine were recorded. |
1994-06-06 |
2023-08-12 |
rat |
| N Mitra, K P Mohanakumar, D K Gangul. Resistance of golden hamster to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: relationship with low levels of regional monoamine oxidase B. Journal of neurochemistry. vol 62. issue 5. 1994-05-18. PMID:8158138. |
effects of acute and chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were investigated for dopamine (da) and its metabolites, 3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxyphenylacetic acid, in nucleus caudatus putamen (ncp), limbic system, and substantia nigra (sn) of golden hamster and balb/c and c57/bl mice to obtain a clue for the variance of mptp toxicity between the strains and species. |
1994-05-18 |
2023-08-12 |
mouse |
| A L Scotti, D Monard, C Nitsc. Re-expression of glia-derived nexin/protease nexin 1 depends on mode of lesion-induction or terminal degeneration: observations after excitotoxin or 6-hydroxydopamine lesions of rat substantia nigra. Journal of neuroscience research. vol 37. issue 2. 1994-05-11. PMID:7908698. |
sustained de novo synthesis of gdn occurred in the dopamine depleted caudate putamen following excitotoxin or 6-hydroxydopamine induced degeneration of the substantia nigra and of the nigrostriatal pathway provided that the lesions were nearly complete. |
1994-05-11 |
2023-08-12 |
rat |