| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L K Nisenbaum, S T Kitai, W R Crowley, C R Gerfe. Temporal dissociation between changes in striatal enkephalin and substance P messenger RNAs following striatal dopamine depletion. Neuroscience. vol 60. issue 4. 1994-10-24. PMID:7523989. |
changes in the levels of enkephalin and substance p messenger rna expression were examined in the striatum following dopamine depletion resulting from unilateral injection of 6-hydroxydopamine into the substantia nigra. |
1994-10-24 |
2023-08-12 |
Not clear |
| R Daniels, G F Harding, S J Anderso. Effect of dopamine and acetylcholine on the visual evoked potential. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 16. issue 2-3. 1994-10-18. PMID:7916338. |
dopamine is a neurotransmitter known to be present in the retina of primates and is found to be severely depleted in the substantia nigra of patients with parkinson's disease. |
1994-10-18 |
2023-08-12 |
Not clear |
| R Y Shen, C A Altar, L A Chiod. Brain-derived neurotrophic factor increases the electrical activity of pars compacta dopamine neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:8090745. |
chronic infusions of brain-derived neurotrophic factor (bdnf) immediately above the substantia nigra augment spontaneous locomotion, rotational behavior, and striatal dopamine (da) turnover, indicating that bdnf increases functions of the nigrostriatal da system. |
1994-10-14 |
2023-08-12 |
Not clear |
| D J Clarke, A P Payn. Neuroanatomical characterization of a new mutant rat with dopamine depletion in the substantia nigra. The European journal of neuroscience. vol 6. issue 5. 1994-10-03. PMID:7915606. |
neuroanatomical characterization of a new mutant rat with dopamine depletion in the substantia nigra. |
1994-10-03 |
2023-08-12 |
rat |
| M G Rosales, G Flores, S Hernández, D Martínez-Fong, J Aceve. Activation of subthalamic neurons produces NMDA receptor-mediated dendritic dopamine release in substantia nigra pars reticulata: a microdialysis study in the rat. Brain research. vol 645. issue 1-2. 1994-09-21. PMID:8062095. |
here we have studied whether the activation of the subthalamic neurons induces the release of dopamine (da) from dopaminergic dendrites in the pars reticulata of the substantia nigra. |
1994-09-21 |
2023-08-12 |
rat |
| D M Bronstein, H Ye, K R Pennypacker, P M Hudson, J S Hon. Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat. Brain research. Molecular brain research. vol 23. issue 3. 1994-09-12. PMID:7914658. |
d1 dopamine (da) receptor agonists induce the expression of the opioid peptide dynorphin (dyn) in the striatum, an effect accentuated several fold by removing the dopaminergic innervation to the striatum (e.g., by lesioning the da cell bodies in the substantia nigra [sn]). |
1994-09-12 |
2023-08-12 |
rat |
| M H Mark, J I Sage, D W Dickson, R E Heikkila, L Manzino, K O Schwarz, R C Duvoisi. Meige syndrome in the spectrum of Lewy body disease. Neurology. vol 44. issue 8. 1994-09-12. PMID:8058144. |
neurochemical analysis of postmortem brain tissue showed evidence for decreased dopamine turnover in the substantia nigra, striatum, and nucleus accumbens. |
1994-09-12 |
2023-08-12 |
Not clear |
| D Nakahara, W Maruyama, H Hashiguti, M Nao. Characterization of the in vivo action of (R)-salsolinol, an endogenous metabolite of alcohol, on serotonin and dopamine metabolism: a microdialysis study. Brain research. vol 644. issue 2. 1994-09-08. PMID:8050034. |
using a microdialysis-hplc technique in conscious rats, we examined the action of (r)-1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (r)-salsolinol (r-sal), a possible endogenous metabolite of alcohol, on serotonin (5-ht) and dopamine (da) metabolism in four regions of the brain: the striatum, the substantia nigra, the hippocampus and the hypothalamus. |
1994-09-08 |
2023-08-12 |
rat |
| T E Robinson, M Noordhoorn, E M Chan, Z Mocsary, D M Camp, I Q Whisha. Relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6-OHDA lesion of the substantia nigra. Synapse (New York, N.Y.). vol 17. issue 1. 1994-08-23. PMID:8042143. |
relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6-ohda lesion of the substantia nigra. |
1994-08-23 |
2023-08-12 |
rat |
| S Chen, X Zhou, D Xu, Q Tang, X X. Parkinsonism induced with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in cats: behavioral, biochemical and pathological studies. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. vol 8. issue 4. 1994-08-12. PMID:8032069. |
reduction of the concentration of dopamine and its metabolites was determined in the substantia nigra and putamen by high performance liquid chromatography (hplc). |
1994-08-12 |
2023-08-12 |
cat |
| L P Martin, B L Waszcza. D1 agonist-induced excitation of substantia nigra pars reticulata neurons: mediation by D1 receptors on striatonigral terminals via a pertussis toxin-sensitive coupling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 7. 1994-08-11. PMID:7913124. |
iontophoresis of dopamine or the d1 agonist skf 38393 has been shown to elicit current-dependent increases in the firing of rat substantia nigra pars reticulata neurons, suggesting a discrete physiological role for the d1 dopamine receptor population in the substantia nigra. |
1994-08-11 |
2023-08-12 |
rat |
| J H Ryu, K Yanai, R Iwata, T Ido, T Watanab. Heterogeneous distributions of histamine H3, dopamine D1 and D2 receptors in rat brain. Neuroreport. vol 5. issue 5. 1994-08-08. PMID:8025257. |
this treatment resulted in similar decreases in histamine h3 and dopamine d1 receptor binding sites in the striatum and ipsilateral substantia nigra. |
1994-08-08 |
2023-08-12 |
rat |
| K D Keegan, G N Woodruff, R D Pinnoc. The pharmacology of neurotensin analogues on neurones in the rat substantia nigra, pars compacta in vitro. European journal of pharmacology. vol 253. issue 1-2. 1994-07-26. PMID:8013539. |
the effects of neurotensin and neurotensin analogues on dopamine neurones were studied in an in vitro slice preparation of rat substantia nigra, pars compacta using extracellular and intracellular recording techniques. |
1994-07-26 |
2023-08-12 |
rat |
| H Sauer, W H Oerte. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience. vol 59. issue 2. 1994-07-21. PMID:7516500. |
in order to develop a rodent model displaying a progressive degeneration of the dopamine neurons of the substantia nigra, we bilaterally injected the tracer substance fluorogold into the terminal field of the nigrostriatal projection, i.e. |
1994-07-21 |
2023-08-12 |
rat |
| O Stork, T Hashimoto, K Obat. Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience research. vol 19. issue 1. 1994-07-20. PMID:7911985. |
the number of th-positive cells was increased for both ish and imhc 8 h after a single administration of benzodiazepine diazepam, which facilitates gabaa-receptor-mediated transmission and reduces dopamine release in the substantia nigra (sn). |
1994-07-20 |
2023-08-12 |
rat |
| O Stork, T Hashimoto, K Obat. Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience research. vol 19. issue 1. 1994-07-20. PMID:7911985. |
in conclusion, gabaergic substances will activate th gene expression in snr neurons (1) through decreasing spontaneous somato-dendritic dopamine release in the substantia nigra and/or (2) by increasing the activity of these neurons. |
1994-07-20 |
2023-08-12 |
rat |
| A C Linthorst, P L van Giersbergen, M Gras, D H Versteeg, W de Jon. The nigrostriatal dopamine system: role in the development of hypertension in spontaneously hypertensive rats. Brain research. vol 639. issue 2. 1994-07-13. PMID:8205480. |
the effects of lesions in the pars compacta of the substantia nigra of 4-week-old spontaneously hypertensive rats (shr) and normotensive wistar-kyoto rats (wky) were studied on (a) changes in blood pressure during a period of 6 weeks following lesioning, and (b) dopamine and metabolite concentrations in the caudate nucleus and (c) the in vitro release of [3h]dopamine from caudate nucleus slices 6 weeks after the lesioning. |
1994-07-13 |
2023-08-12 |
rat |
| H Q Wu, R Schwarcz, P D Shepar. Excitatory amino acid-induced excitation of dopamine-containing neurons in the rat substantia nigra: modulation by kynurenic acid. Synapse (New York, N.Y.). vol 16. issue 3. 1994-06-27. PMID:7515199. |
kynurenic acid (kyna), an endogenous antagonist of ionotropic excitatory amino acid (eaa) receptors, was tested for its ability to modulate n-methyl-d-aspartate (nmda)- and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa)-induced excitation of dopamine (da)-containing neurons in the zona compacta of the rat substantia nigra (snc). |
1994-06-27 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. |
1994-06-23 |
2023-08-12 |
rat |
| F G Fernandes Xavier, G Doucet, M Geffard, L Descarrie. Dopamine neoinnervation in the substantia nigra and hyperinnervation in the interpeduncular nucleus of adult rat following neonatal cerebroventricular administration of 6-hydroxydopamine. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:8190274. |
an aberrant network of dopamine axons was found to pervade the rat substantia nigra following neonatal destruction of its dopamine nerve cell bodies and dendrites by cerebroventricular administration of 6-hydroxydopamine. |
1994-06-23 |
2023-08-12 |
rat |