| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert J Carey, Ernest N Damianopoulo. Serotonin and conditioning: focus on Pavlovian psychostimulant drug conditioning. Behavioural brain research. vol 282. 2015-09-21. PMID:25446748. |
serotonin containing neurons are located in nuclei deep in the brainstem and send axons throughout the central nervous system from the spinal cord to the cerebral cortex. |
2015-09-21 |
2023-08-13 |
Not clear |
| Hai Lin, Bong Ha Heo, Woong Mo Kim, Yong Chul Kim, Myung Ha Yoo. Antiallodynic effect of tianeptine via modulation of the 5-HT7 receptor of GABAergic interneurons in the spinal cord of neuropathic rats. Neuroscience letters. vol 598. 2015-09-14. PMID:25982324. |
we examined the antiallodynic effect of intrathecal tianeptine in neuropathic pain rats and determined the involvement of 5-hydroxytryptamine type 7 (5-ht7) receptor of the gabaergic interneurons in the spinal cord. |
2015-09-14 |
2023-08-13 |
rat |
| Matthew I Becker, David Parke. Changes in functional properties and 5-HT modulation above and below a spinal transection in lamprey. Frontiers in neural circuits. vol 8. 2015-07-30. PMID:25653594. |
these results show changes in 5-ht modulation and cellular and synaptic properties after recovery from a spinal cord transection. |
2015-07-30 |
2023-08-13 |
Not clear |
| Mousumi Ghosh, Damien D Pears. The role of the serotonergic system in locomotor recovery after spinal cord injury. Frontiers in neural circuits. vol 8. 2015-07-30. PMID:25709569. |
following spinal cord injury (sci) there is a disruption of descending serotonergic projections to spinal motor areas, which results in a subsequent depletion in 5-ht, the dysregulation of 5-ht transporters as well as the elevated expression, super-sensitivity and/or constitutive auto-activation of specific 5-ht receptors. |
2015-07-30 |
2023-08-13 |
Not clear |
| Mousumi Ghosh, Damien D Pears. The role of the serotonergic system in locomotor recovery after spinal cord injury. Frontiers in neural circuits. vol 8. 2015-07-30. PMID:25709569. |
another approach has been to employ cell therapeutics to replace the loss of descending serotonergic input to the cpg, either through transplanted fetal brainstem 5-ht neurons at the site of injury that can supply 5-ht to below the level of the lesion or by other cell types to provide a substrate at the injury site for encouraging serotonergic axon regrowth across the lesion to the caudal spinal cord for restoring locomotion. |
2015-07-30 |
2023-08-13 |
Not clear |
| Caroline P Klein, Nathalia D M Sperotto, Izaque S Maciel, Carlos E Leite, Alessandra H Souza, Maria M Campo. Effects of D-series resolvins on behavioral and neurochemical changes in a fibromyalgia-like model in mice. Neuropharmacology. vol 86. 2015-07-14. PMID:24929111. |
the induction of fibromyalgia by reserpine triggered a marked decrease of dopamine and serotonin (5-ht) levels, as examined in total brain, spinal cord, cortex and thalamus. |
2015-07-14 |
2023-08-13 |
mouse |
| Caroline P Klein, Nathalia D M Sperotto, Izaque S Maciel, Carlos E Leite, Alessandra H Souza, Maria M Campo. Effects of D-series resolvins on behavioral and neurochemical changes in a fibromyalgia-like model in mice. Neuropharmacology. vol 86. 2015-07-14. PMID:24929111. |
chronic treatment with rvd2 prevented 5-ht reduction in total brain, and reversed the glutamate increases in total brain and spinal cord. |
2015-07-14 |
2023-08-13 |
mouse |
| Seiko Yasuda, Mitsuhiro Yoshida, Hirotaka Yamagata, Yasutake Iwanaga, Hiromi Suenaga, Kozo Ishikawa, Masako Nakano, Satoshi Okuyama, Yoshiko Furukawa, Shoei Furukawa, Toshizo Ishikaw. Imipramine ameliorates pain-related negative emotion via induction of brain-derived neurotrophic factor. Cellular and molecular neurobiology. vol 34. issue 8. 2015-06-10. PMID:25156823. |
changes in perk1/2 (immunohistochemistry), 5-ht and bdnf (elisa), and bdnf mrna (rt-pcr) were measured in the anterior cingulate cortex (acc), rostral ventromedial medulla (rvm), and spinal cord. |
2015-06-10 |
2023-08-13 |
rat |
| Florian Gackière, Laurent Vina. Serotonergic modulation of post-synaptic inhibition and locomotor alternating pattern in the spinal cord. Frontiers in neural circuits. vol 8. 2015-05-15. PMID:25221477. |
experiments aimed at either reducing the endogenous level of serotonin in the spinal cord or blocking the activation of 5-ht2 receptors. |
2015-05-15 |
2023-08-13 |
rat |
| Alexander Drobyshevsky, Silvia Honda Takada, Kehuan Luo, Matthew Derrick, Lei Yu, Katharina A Quinlan, Jeannette Vasquez-Vivar, Maria Inês Nogueira, Sidhartha Ta. Elevated spinal monoamine neurotransmitters after antenatal hypoxia-ischemia in rabbit cerebral palsy model. Journal of neurochemistry. vol 132. issue 4. 2015-04-17. PMID:25421613. |
following prenatal hypoxia-ischemia, newborn rabbits exhibit elevated levels of serotonin in the spinal cord that were linked to muscle hypertonia. |
2015-04-17 |
2023-08-13 |
rabbit |
| Urszula Sławińska, Krzysztof Miazga, Larry M Jorda. The role of serotonin in the control of locomotor movements and strategies for restoring locomotion after spinal cord injury. Acta neurobiologiae experimentalis. vol 74. issue 2. 2015-04-06. PMID:24993627. |
the role of serotonin in the control of locomotor movements and strategies for restoring locomotion after spinal cord injury. |
2015-04-06 |
2023-08-13 |
rat |
| Urszula Sławińska, Krzysztof Miazga, Larry M Jorda. The role of serotonin in the control of locomotor movements and strategies for restoring locomotion after spinal cord injury. Acta neurobiologiae experimentalis. vol 74. issue 2. 2015-04-06. PMID:24993627. |
the other possibility to encourage the remaining spinal cord circuitry below the total transection to control recovery of plantar hindlimb stepping is restoration of serotonergic innervation by intraspinal grafting of embryonic 5-ht neurons. |
2015-04-06 |
2023-08-13 |
rat |
| Misty M Strain, Sierra D Kauer, Tina Kao, Michele R Brumle. Inter- and intralimb adaptations to a sensory perturbation during activation of the serotonin system after a low spinal cord transection in neonatal rats. Frontiers in neural circuits. vol 8. 2015-03-30. PMID:25071461. |
this study demonstrates the sensitivity of the isolated spinal cord to sensory feedback in conjunction with serotonin modulation. |
2015-03-30 |
2023-08-13 |
human |
| Urszula Sławińska, Krzysztof Miazga, Larry M Jorda. 5-HT₂ and 5-HT₇ receptor agonists facilitate plantar stepping in chronic spinal rats through actions on different populations of spinal neurons. Frontiers in neural circuits. vol 8. 2015-03-30. PMID:25191231. |
these receptors are involved in control of locomotor movements, but it is not clear how they are implicated in the responses to 5-ht agonists observed after spinal cord injury. |
2015-03-30 |
2023-08-13 |
mouse |
| Hajime Hoshino, Hideaki Obata, Kunie Nakajima, Rie Mieda, Shigeru Sait. The antihyperalgesic effects of intrathecal bupropion, a dopamine and noradrenaline reuptake inhibitor, in a rat model of neuropathic pain. Anesthesia and analgesia. vol 120. issue 2. 2015-03-18. PMID:25427287. |
antidepressants are often used for the treatment of neuropathic pain, and their analgesic effects rely on increased noradrenaline and serotonin levels in the spinal cord. |
2015-03-18 |
2023-08-13 |
rat |
| Di Wang, Sten Grillner, Peter Wallé. Endogenous release of 5-HT modulates the plateau phase of NMDA-induced membrane potential oscillations in lamprey spinal neurons. Journal of neurophysiology. vol 112. issue 1. 2015-02-23. PMID:24740857. |
here, we characterize these two types of membrane potential oscillations and show that they depend on the level of endogenous release of 5-ht in the spinal cord preparations. |
2015-02-23 |
2023-08-13 |
Not clear |
| Antonio Rodríguez-Gaztelumendi, María Luisa Rojo, Angel Pazos, Alvaro Día. An altered spinal serotonergic system contributes to increased thermal nociception in an animal model of depression. Experimental brain research. vol 232. issue 6. 2015-01-26. PMID:24584836. |
autoradiographic studies demonstrated down-regulation of 5-ht transporters ([(3)h]citalopram binding) and decreased functionality of 5-ht1a receptors (8-oh-dpat-stimulated [(35)s]gtpγs binding) in the dorsal horn of the lumbar spinal cord in ob rats. |
2015-01-26 |
2023-08-12 |
rat |
| Antonio Rodríguez-Gaztelumendi, María Luisa Rojo, Angel Pazos, Alvaro Día. An altered spinal serotonergic system contributes to increased thermal nociception in an animal model of depression. Experimental brain research. vol 232. issue 6. 2015-01-26. PMID:24584836. |
in these animals, autoradiographic studies revealed further down-regulation of 5-ht transporters and normalization in the functionality of 5-ht1a receptors on the spinal cord. |
2015-01-26 |
2023-08-12 |
rat |
| Chuan-Xiang Xu, Hong-Tao Liu, Jing Wan. Changes of 5-hydroxytryptamine and tryptophan hydroxylase expression in the ventral horn of spinal cord. Neuroscience bulletin. vol 24. issue 1. 2014-12-14. PMID:18273073. |
changes of 5-hydroxytryptamine and tryptophan hydroxylase expression in the ventral horn of spinal cord. |
2014-12-14 |
2023-08-12 |
Not clear |
| Chuan-Xiang Xu, Hong-Tao Liu, Jing Wan. Changes of 5-hydroxytryptamine and tryptophan hydroxylase expression in the ventral horn of spinal cord. Neuroscience bulletin. vol 24. issue 1. 2014-12-14. PMID:18273073. |
to investigate changes of 5-hydroxytryptamine (5-ht) and its synthesis rate-limiting enzyme tryptophan hydroxylase (tph) in the ventral horn of spinal cord after exercise-induced fatigue, and to further discuss the mechanism of exercise-induced central fatigue at spinal level. |
2014-12-14 |
2023-08-12 |
Not clear |