| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsuya Sakimura, Tatsuya Maekawa, Kazuo Sasagawa, Yukihito Ishii, Shin-Ichi Kume, Takeshi Oht. Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus. Clinical and experimental pharmacology & physiology. 2019-11-20. PMID:29757463. |
furthermore, there were significant changes in 5-ht concentrations in the prefrontal cortex, and in gaba and glutamate concentrations in the hippocampus in sdt fatty compared with controls. |
2019-11-20 |
2023-08-13 |
rat |
| Paula Sm Yamashita, Daiane S Rosa, Christopher A Lowry, Helio Zangross. Serotonin actions within the prelimbic cortex induce anxiolysis mediated by serotonin 1a receptors. Journal of psychopharmacology (Oxford, England). 2019-11-20. PMID:30565963. |
administration of serotonin or the serotonin 1a receptor agonist, (±)-8-hydroxy-2-(dipropylamino)tetralin (8-oh-dpat), into the prefrontal cortex, inhibits anxiety-like responses. |
2019-11-20 |
2023-08-13 |
Not clear |
| Kodai Hino, Tomoko Kimura, Jun Udagaw. Handling has an anxiolytic effect that is not affected by the inhibition of the protein kinase C pathway in adult prenatal undernourished male rat offspring. Congenital anomalies. 2019-11-20. PMID:30883939. |
conversely, the concentrations of dopamine, serotonin, norepinephrine, and their metabolites were not altered in the prefrontal cortex by prenatal undernutrition or daily handling after weaning. |
2019-11-20 |
2023-08-13 |
rat |
| Marcelo Gomes de Gomes, Leandro Cattelan Souza, André Rossito Goes, Lucian Del Fabbro, Carlos Borges Filho, Franciele Donato, Marina Prigol, Cristiane Luchese, Silvane Souza Roman, Robson Luiz Puntel, Silvana Peterini Boeira, Cristiano Ricardo Jess. Fish oil ameliorates sickness behavior induced by lipopolysaccharide in aged mice through the modulation of kynurenine pathway. The Journal of nutritional biochemistry. vol 58. 2019-10-28. PMID:29870875. |
moreover, we evaluated the ability of fo treatment on the regulation of neuroinflammation (levels of interleukin-1β, interleukin-6, tumor factor necrosis-α and interferon-γ), kp biomarkers (levels of tryptophan, kynurenine, kynurenic acid, 3-hydroxykynurenine and quinolinic acid and activities of indoleamine-2,3-dioxygenase, kynurenine monooxygenase and kynurenine aminotransferase) and serotonergic system (levels of serotonin and 5-hydroxyindoleactic acid) in the hippocampus, striatum and prefrontal cortex of lps-treated mice. |
2019-10-28 |
2023-08-13 |
mouse |
| Jia-Ning Xu, Li-Fang Chen, Jun Su, Zhi-Li Liu, Jie Chen, Qing-Fen Lin, Wei-Dong Mao, Dong She. The anxiolytic-like effects of ginsenoside Rg3 on chronic unpredictable stress in rats. Scientific reports. vol 8. issue 1. 2019-10-24. PMID:29773855. |
in addition, the decreased levels on progesterone, allopregnanolone, serotonin (5-ht) in the prefrontal cortex and hippocampus of chronic unpredictable stress (cus) were blocked by grg3 (20 and 40 mg/kg, i.g). |
2019-10-24 |
2023-08-13 |
rat |
| Amanda L Blaker, Bryan K Yamamot. Methamphetamine-Induced Brain Injury and Alcohol Drinking. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 13. issue 1. 2019-10-02. PMID:28856500. |
meth alone depleted dopamine and serotonin in the striatum, as well as serotonin in the prefrontal cortex when measured 1 week later. |
2019-10-02 |
2023-08-13 |
rat |
| Amanda L Blaker, Bryan K Yamamot. Methamphetamine-Induced Brain Injury and Alcohol Drinking. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 13. issue 1. 2019-10-02. PMID:28856500. |
in contrast, etoh drinking alone did not affect dopamine and serotonin content in the striatum and prefrontal cortex, but prior etoh drinking followed by injections of meth enhanced meth-induced depletions of dopamine, serotonin, as well as dopamine and serotonin transporter immunoreactivities in a manner that was correlated with the degree of etoh consumption. |
2019-10-02 |
2023-08-13 |
rat |
| E Moreton, P Baron, S Tiplady, S McCall, B Clifford, S C Langley-Evans, K C F Fone, J P Voig. Impact of early exposure to a cafeteria diet on prefrontal cortex monoamines and novel object recognition in adolescent rats. Behavioural brain research. vol 363. 2019-08-30. PMID:30735761. |
to this end, wistar rat dams were fed a high caloric cafeteria diet (cd) during lactation and resultant 24-26 day old offspring exposed to nor testing and simultaneous pfc dopamine and serotonin metabolism measurement. |
2019-08-30 |
2023-08-13 |
rat |
| E Moreton, P Baron, S Tiplady, S McCall, B Clifford, S C Langley-Evans, K C F Fone, J P Voig. Impact of early exposure to a cafeteria diet on prefrontal cortex monoamines and novel object recognition in adolescent rats. Behavioural brain research. vol 363. 2019-08-30. PMID:30735761. |
pfc dopamine metabolism was significantly reduced in the cd group (p < 0.001), whereas serotonin metabolism was increased (p < 0.001). |
2019-08-30 |
2023-08-13 |
rat |
| E Moreton, P Baron, S Tiplady, S McCall, B Clifford, S C Langley-Evans, K C F Fone, J P Voig. Impact of early exposure to a cafeteria diet on prefrontal cortex monoamines and novel object recognition in adolescent rats. Behavioural brain research. vol 363. 2019-08-30. PMID:30735761. |
these results suggest that an obesogenic lactational diet can have a detrimental impact on cognition in adolescent offspring associated with aberrant pfc serotonin and dopamine metabolism. |
2019-08-30 |
2023-08-13 |
rat |
| María-Aránzazu Martínez, Irma Ares, José-Luis Rodríguez, Marta Martínez, María-Rosa Martínez-Larrañaga, Arturo Anadó. Neurotransmitter changes in rat brain regions following glyphosate exposure. Environmental research. vol 161. 2019-08-28. PMID:29156344. |
moreover, glyphosate, dose-dependent, evoked a statistically significant increase in 5-ht turnover in striatum and hypothalamus and in da turnover in prefrontal cortex and hippocampus, and a statistically significant decrease in ne turnover in prefrontal cortex and hypothalamus. |
2019-08-28 |
2023-08-13 |
rat |
| Wei Hung Chang, I Hui Lee, Mei Hung Chi, Shih-Hsien Lin, Kao Chin Chen, Po See Chen, Nan Tsing Chiu, Wei Jen Yao, Yen Kuang Yan. Prefrontal cortex modulates the correlations between brain-derived neurotrophic factor level, serotonin, and the autonomic nervous system. Scientific reports. vol 8. issue 1. 2019-08-16. PMID:29416077. |
prefrontal cortex modulates the correlations between brain-derived neurotrophic factor level, serotonin, and the autonomic nervous system. |
2019-08-16 |
2023-08-13 |
human |
| Wei Hung Chang, I Hui Lee, Mei Hung Chi, Shih-Hsien Lin, Kao Chin Chen, Po See Chen, Nan Tsing Chiu, Wei Jen Yao, Yen Kuang Yan. Prefrontal cortex modulates the correlations between brain-derived neurotrophic factor level, serotonin, and the autonomic nervous system. Scientific reports. vol 8. issue 1. 2019-08-16. PMID:29416077. |
however, the way in which the pfc modulates downstream neuro-networks in terms of serotonin and the autonomic nervous system (ans) by variation in the level of brain-derived neurotrophic factor (bdnf) is still unclear. |
2019-08-16 |
2023-08-13 |
human |
| Laila Abdel-Hafiz, Andreas Müller-Schiffmann, Carsten Korth, Benedetta Fazari, Owen Y Chao, Susanne Nikolaus, Sandra Schäble, Arne Herring, Kathy Keyvani, Valéria Lamounier-Zepter, Joseph P Huston, Maria A de Souza Silv. Aβ dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease. Neurobiology of aging. vol 69. 2019-05-21. PMID:29803148. |
in 7- and 12-month-old mice, levels of acetylcholine, dopamine, and serotonin were measured in neostriatum, ventral striatum, prefrontal cortex, hippocampus, amygdala, and entorhinal cortex by high-performance liquid chromatography. |
2019-05-21 |
2023-08-13 |
mouse |
| Manjun Shen, Yi Yang, Ying Wu, Beibei Zhang, Haishan Wu, Lu Wang, Hui Tang, Jindong Che. L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress rat model via modulating the monoamine levels in limbic-cortical-striatal-pallidal-thalamic-circuit related brain regions. Phytotherapy research : PTR. vol 33. issue 2. 2019-05-21. PMID:30474152. |
the monoamine neurotransmitters that involve serotonin (5-ht), norepinephrine (ne), and dopamine (da) were measured in the limbic-cortical-striatal-pallidal-thalamic (lcspt)-circuit related brain regions, including the prefrontal cortex (pfc), nucleus accumbens (nac), striatum (st), amygdala, and hippocampus (hip). |
2019-05-21 |
2023-08-13 |
rat |
| Manjun Shen, Yi Yang, Ying Wu, Beibei Zhang, Haishan Wu, Lu Wang, Hui Tang, Jindong Che. L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress rat model via modulating the monoamine levels in limbic-cortical-striatal-pallidal-thalamic-circuit related brain regions. Phytotherapy research : PTR. vol 33. issue 2. 2019-05-21. PMID:30474152. |
in the pfc, nac, and hip, l-theanine administration significantly increased the levels of 5-ht, ne, and da. |
2019-05-21 |
2023-08-13 |
rat |
| Juan Facundo Morici, Magdalena Miranda, Francisco Tomás Gallo, Belén Zanoni, Pedro Bekinschtein, Noelia V Weisstau. 5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex. eLife. vol 7. 2019-05-15. PMID:29717980. |
in a contextual version of the object recognition task, we examined the effect of medial pfc (mpfc) serotonin 2a receptor (5-ht2ar) blockade during retrieval in reconsolidation of competing objects memories. |
2019-05-15 |
2023-08-13 |
rat |
| F Tollens, N Gass, R Becker, A J Schwarz, C Risterucci, B Künnecke, P Lebhardt, J Reinwald, M Sack, W Weber-Fahr, A Meyer-Lindenberg, A Sartoriu. The affinity of antipsychotic drugs to dopamine and serotonin 5-HT European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 9. 2019-05-03. PMID:30006253. |
therefore, we examined the relationship between the affinities of three second-generation antipsychotics (amisulpride, risperidone and olanzapine) to dopamine and serotonin receptors and fc patterns related to the prefrontal cortex (pfc) and striatum in sprague-dawley rats. |
2019-05-03 |
2023-08-13 |
rat |
| Matthew W Hale, Jodi L Lukkes, Kathleen F Dady, Kyle J Kelly, Evan D Paul, David G Smith, Jared D Heinze, Charles L Raison, Christopher A Lowr. Interactions between whole-body heating and citalopram on body temperature, antidepressant-like behaviour, and neurochemistry in adolescent male rats. Behavioural brain research. vol 359. 2019-04-23. PMID:30468787. |
in these experiments, we examined the effects of whole-body heating, either with or without treatment of a suprathreshold dose of citalopram (20 mg/kg, s.c.), on body temperature, antidepressant-like behavioural responses in the forced swim test, and tissue concentrations of serotonin and its metabolite, 5-hydoxyindoleacetic acid (5-hiaa), in the prefrontal cortex of adolescent male wistar rats. |
2019-04-23 |
2023-08-13 |
rat |
| Yosuke Hiraki, Ryota Araki, Hironori Fujiwara, Yukio Ago, Tatsunori Tanaka, Kazufumi Toume, Kinzo Matsumoto, Takeshi Yab. Kamiuntanto increases prefrontal extracellular serotonin levels and ameliorates depression-like behaviors in mice. Journal of pharmacological sciences. vol 139. issue 2. 2019-04-17. PMID:30545726. |
in vivo microdialysis showed that kut (1000 mg/kg) transiently increased the level of extracellular serotonin (5-ht) in the prefrontal cortex. |
2019-04-17 |
2023-08-13 |
mouse |