| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Betina Elfving, Heidi Kaastrup Müller, Ignasi Oliveras, Tina Becher Østerbøg, Cristobal Rio-Alamos, Ana Sanchez-Gonzalez, Adolf Tobeña, Alberto Fernandez-Teruel, Susana Azna. Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior. Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-28. PMID:31228641. |
the inbred roman high- (rha-i) and low- (rla-i) avoidance rat strains are a congenital neurobehavioral model, with the rha-i displaying schizophrenia-related behaviors and serotonin 2a (5-ht2a) and metabotropic glutamate 2 (mglu2) receptor alterations in the prefrontal cortex (pfc). |
2020-08-28 |
2023-08-13 |
rat |
| Ryuji Sakakibar. Editorial Comment to Serotonin in the rat prefrontal cortex controls the micturition reflex through 5-hydroxytryptamine 2A and 5-hydroxytryptamine 7 receptors. International journal of urology : official journal of the Japanese Urological Association. vol 27. issue 8. 2020-08-27. PMID:32533594. |
editorial comment to serotonin in the rat prefrontal cortex controls the micturition reflex through 5-hydroxytryptamine 2a and 5-hydroxytryptamine 7 receptors. |
2020-08-27 |
2023-08-13 |
rat |
| Qiaohui Lu, Akihiro Mouri, Yang Yang, Kazuo Kunisawa, Tomoaki Teshigawara, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Zou Libo, Toshitaka Nabeshima, Kuniaki Sait. Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression. Behavioural brain research. vol 372. 2020-08-19. PMID:31288060. |
the level of serotonin and protein levels of tryptophan hydroxylase (tph) and th were decreased by cums in the hippocampus (hpc) and prefrontal cortex (pfc). |
2020-08-19 |
2023-08-13 |
mouse |
| Chia-Li Wei, Sabrina Wang, Jui-Ting Yen, Yun-Fang Cheng, Chia-Li Liao, Chih-Chieh Hsu, Chien-Chen Wu, Ying-Chieh Tsa. Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms. Brain research. vol 1711. 2020-08-04. PMID:30684456. |
in addition, live ps23 also reverses corticosterone-reduced serotonin levels in hippocampus, prefrontal cortex and striatum; whereas heat-killed ps23 reverses corticosterone-reduced dopamine levels in hippocampus and prefrontal cortex. |
2020-08-04 |
2023-08-13 |
mouse |
| Jeane Cristina F Vieira, Taysa B Bassani, Ronise M Santiago, Gisele de O Guaita, Janaína M Zanoveli, Claudio da Cunha, Maria A B F Vita. Anxiety-like behavior induced by 6-OHDA animal model of Parkinson's disease may be related to a dysregulation of neurotransmitter systems in brain areas related to anxiety. Behavioural brain research. vol 371. 2020-06-23. PMID:31141725. |
in addition, while the serotonin levels were reduced in the striatum and prefrontal cortex, it was increased in the amygdala. |
2020-06-23 |
2023-08-13 |
rat |
| Derya Sargin, Ha-Seul Jeoung, Nathalie M Goodfellow, Evelyn K Lamb. Serotonin Regulation of the Prefrontal Cortex: Cognitive Relevance and the Impact of Developmental Perturbation. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:31259523. |
serotonin regulation of the prefrontal cortex: cognitive relevance and the impact of developmental perturbation. |
2020-06-11 |
2023-08-13 |
Not clear |
| Derya Sargin, Ha-Seul Jeoung, Nathalie M Goodfellow, Evelyn K Lamb. Serotonin Regulation of the Prefrontal Cortex: Cognitive Relevance and the Impact of Developmental Perturbation. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:31259523. |
this work is broadly consistent with ex vivo research investigating how 5-ht regulates prefrontal cortex and its output projections. |
2020-06-11 |
2023-08-13 |
Not clear |
| Coralie Berthoux, Alexander Barre, Joël Bockaert, Philippe Marin, Carine Bécame. Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 4. 2020-05-22. PMID:29917056. |
among the 5-ht receptors abundantly expressed in pfc, 5-ht2a receptors located in dendrites of layer v pyramidal neurons control neuronal excitability and mediate the psychotropic effects of psychedelic hallucinogens, but their impact on glutamatergic transmission and synaptic plasticity remains poorly characterized. |
2020-05-22 |
2023-08-13 |
mouse |
| Coralie Berthoux, Alexander Barre, Joël Bockaert, Philippe Marin, Carine Bécame. Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 4. 2020-05-22. PMID:29917056. |
here, we show that a 20-min exposure of mouse pfc slices to serotonin or the 5-ht2a receptor agonist 2,5-dimethoxy-4-iodoamphetamine (doi) produces a long-lasting depression of evoked ampa excitatory postsynaptic currents in layer v pyramidal neurons. |
2020-05-22 |
2023-08-13 |
mouse |
| Peijun Tian, Renying Zou, Linhong Song, Xu Zhang, Bin Jiang, Gang Wang, Yuan-Kun Lee, Jianxin Zhao, Hao Zhang, Wei Che. Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota. Food & function. vol 10. issue 11. 2020-04-16. PMID:31687714. |
administration of ccfm687 in mice significantly improved the scores in behavioral tests and increased the level of 5-htp and serotonin (5-ht) in the prefrontal cortex (pfc) of the brain. |
2020-04-16 |
2023-08-13 |
mouse |
| Jiao Yang, Qingyi Huang, Huan Liu, Xiong Zhou, Zhuoquan Huang, Quansheng Peng, Chunhong Li. 4-Nonylphenol and 4-tert-octylphenol induce anxiety-related behaviors through alternation of 5-HT receptors and transporters in the prefrontal cortex. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 230. 2020-04-06. PMID:31911191. |
4-nonylphenol and 4-tert-octylphenol induce anxiety-related behaviors through alternation of 5-ht receptors and transporters in the prefrontal cortex. |
2020-04-06 |
2023-08-13 |
human |
| Lisha Jin, Sisi Zhou, Shujie Zhu, Shaowei Lei, Weijuan Du, Huidi Jiang, Su Zeng, Hui Zho. Dehydrocorydaline induced antidepressant-like effect in a chronic unpredictable mild stress mouse model via inhibiting uptake-2 monoamine transporters. European journal of pharmacology. vol 864. 2020-03-25. PMID:31604070. |
we evaluated the mechanism of action of dehydrocorydaline by examining the levels of monoamine transmitters (5-ht, ne and da) in the prefrontal cortex in chronic unpredictable mild stress mice. |
2020-03-25 |
2023-08-13 |
mouse |
| Alexis Faure, Francesca Zoratto, Doriana Chirico, Emilia Romano, Rosanna Mancinelli, Luciano Saso, Jacques Callebert, Giovanni Laviola, Sylvie Granon, Walter Adrian. Reduced adolescent risk-assessment and lower nicotinic beta-2 expression in rats exposed to nicotine through lactation by forcedly drinking dams. Neuroscience. vol 413. 2020-03-09. PMID:31228592. |
brain analyses at adulthood suggest that, in prefrontal cortex, nicotine per se reduced serotonin, while the maternal overcare reduced chrn-b2 gene-expression. |
2020-03-09 |
2023-08-13 |
rat |
| M Soiza-Reilly, F J Meye, J Olusakin, L Telley, E Petit, X Chen, M Mameli, D Jabaudon, J-Y Sze, P Gaspa. SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior. Molecular psychiatry. vol 24. issue 5. 2020-03-03. PMID:30279456. |
complete or cortex-specific ablation of sert increases the number of functional pfc glutamate synapses on both 5-ht and gaba neurons in the drn. |
2020-03-03 |
2023-08-13 |
mouse |
| Shijia Li, Jun Tang, Yan Gao, Christiane M Thiel, Oliver T Wol. The serotonin transporter gene variants modulate acute stress-induced hippocampus and dorsomedial prefrontal cortex activity during memory retrieval. PsyCh journal. vol 8. issue 3. 2020-02-03. PMID:31264389. |
the serotonin transporter gene variants modulate acute stress-induced hippocampus and dorsomedial prefrontal cortex activity during memory retrieval. |
2020-02-03 |
2023-08-13 |
human |
| Debapriya Garabadu, Vivek Kuma. Celecoxib potentiates the antianxiety and anticompulsive-like activity of fluoxetine against chronic unpredictable mild stress in experimental animals. Behavioural pharmacology. vol 30. issue 2 and 3-Spec Issue. 2020-01-06. PMID:30724800. |
celecoxib significantly reversed the cums-induced decrease and increase in the levels of serotonin (5-ht) and its metabolite (5-hydroxyindole acetic acid) in the prefrontal cortex, and attenuated the cums-induced increase in the levels of inflammatory markers such as interleukin-6 and tumor necrosis factor-α, and apoptosis marker caspase-3 in the prefrontal cortex. |
2020-01-06 |
2023-08-13 |
mouse |
| Hadeer Emam, David C Steffens, Godfrey D Pearlson, Lihong Wan. Increased ventromedial prefrontal cortex activity and connectivity predict poor sertraline treatment outcome in late-life depression. International journal of geriatric psychiatry. vol 34. issue 5. 2019-12-20. PMID:30761621. |
previous studies of imaging predictors on acute treatment response in late-life depression (lld) demonstrated that poor response to selective serotonin reuptake inhibitors (ssris) is associated with pre-treatment low functional connectivity (fc) within executive control network and high fc within default-mode network including the ventromedial prefrontal cortex (vmpfc). |
2019-12-20 |
2023-08-13 |
Not clear |
| Hanna J Szkudlarek, Sagar J Desai, Justine Renard, Brian Pereira, Christopher Norris, Christina E L Jobson, Nagalingam Rajakumar, Brian L Allman, Steven R Laviolett. Δ-9-Tetrahydrocannabinol and Cannabidiol produce dissociable effects on prefrontal cortical executive function and regulation of affective behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30538288. |
interestingly, the effects of pfc thc vs. cbd were found to be mediated through dissociable cb1 vs. 5-ht |
2019-11-25 |
2023-08-13 |
rat |
| Paola Brivio, Judith R Homberg, Marco A Riva, Francesca Calabres. Alterations of Glutamatergic Markers in the Prefrontal Cortex of Serotonin Transporter Knockout Rats: A Developmental Timeline. Cellular and molecular neurobiology. vol 39. issue 5. 2019-11-22. PMID:30915622. |
alterations of glutamatergic markers in the prefrontal cortex of serotonin transporter knockout rats: a developmental timeline. |
2019-11-22 |
2023-08-13 |
rat |
| Pau Celada, M. Victoria Puig, Raúl Martín-Ruiz, Josep M. Casanovas, Francesc Artiga. Control of the serotonergic system by the medial prefrontal cortex: potential role in the etiology of PTSD and depressive disorders. Neurotoxicity research. vol 4. issue 5-6. 2019-11-20. PMID:12754155. |
serotonergic neurons of the midbrain rapbe nuclei innervate the prefrontal cortex and are the cellular target for drugs used to treat mood disorders such as the selective serotonin (5-ht) reuptake inhibitors. |
2019-11-20 |
2023-08-12 |
Not clear |