| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Gokdemir, C Cetinkaya, H Gumus, I Aksu, M Kiray, M Ates, A Kiray, B Baykara, B Baykara, A R Sisman, N Uysa. The effect of exercise on anxiety- and depression-like behavior of aged rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 95. issue 1. 2020-11-13. PMID:31264480. |
we assessed serum corticosterone levels; number of amygdala, hippocampus and prefrontal cortex cells; tissue serotonin and serotonin 1a (5-ht1a) levels. |
2020-11-13 |
2023-08-13 |
rat |
| Marta Bosia, Margherita Bechi, Adele Pirovano, Mariachiara Buonocore, Cristina Lorenzi, Federica Cocchi, Placido Bramanti, Enrico Smeraldi, Roberto Cavallar. COMT and 5-HT1A-receptor genotypes potentially affect executive functions improvement after cognitive remediation in schizophrenia. Health psychology and behavioral medicine. vol 2. issue 1. 2020-10-01. PMID:25750798. |
recent studies proved that serotonin 1a receptor (5-ht1a-r) regulates dopamine in the prefrontal cortex (pfc), and clinical works suggested a 5-ht1a-r role in cognition. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
elevated thyroid peroxidase antibody increases risk of post-partum depression by decreasing prefrontal cortex bdnf and 5-ht levels in mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
furthermore, in the prefrontal cortex, the mrna and protein expression levels of brain-derived neurotrophic factor (bdnf) were measured, serotonin (5-ht) levels were measured by ultra-high-performance liquid chromatography-tandem mass-spectrometry (uhplc-ms/ms), and total thyroxine (tt4) levels were determined by elisa. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
compared with the controls, the mice immunized with mtpo-ad displayed depressive behaviors, with a significantly lower sucrose preference (sp) at the 12-h time point and a longer immobility time in the fst and tst, which were accompanied by a lower expression of bdnf and 5-ht but no change in the tt4 concentration in the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
together, these findings suggest that elevated tpoab may increase the risk of subsequent ppd and decrease the concentration of bdnf and 5-ht in the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
mouse |
| Andrea Forero, Olga Rivero, Sina Wäldchen, Hsing-Ping Ku, Dominik P Kiser, Yvonne Gärtner, Laura S Pennington, Jonas Waider, Patricia Gaspar, Charline Jansch, Frank Edenhofer, Thérèse J Resink, Robert Blum, Markus Sauer, Klaus-Peter Lesc. Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:29018333. |
cadherin-13 deficiency increases dorsal raphe 5-ht neuron density and prefrontal cortex innervation in the mouse brain. |
2020-10-01 |
2023-08-13 |
mouse |
| Hao Ma, Weiping Wang, Shaofeng Xu, Ling Wang, Xiaoliang Wan. Potassium 2-(1-hydroxypentyl)-benzoate improves depressive-like behaviors in rat model. Acta pharmaceutica Sinica. B. vol 8. issue 6. 2020-10-01. PMID:30505657. |
in addition, phpb could reverse the reduced level of extracellular 5-ht and its metabolite 5-hiaa in prefrontal cortex (pfc) of depressed rats. |
2020-10-01 |
2023-08-13 |
rat |
| Zheng Gu, Liujie Chu, Yaqiong Ha. Therapeutic effect of resveratrol on mice with depression. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30936978. |
dopamine (da) and serotoni (5-ht) and the level of brain-derived nerve growth factor (bdnf) in the prefrontal cortex of each group were analyzed by elisa. |
2020-10-01 |
2023-08-13 |
mouse |
| Zheng Gu, Liujie Chu, Yaqiong Ha. Therapeutic effect of resveratrol on mice with depression. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30936978. |
compared with the model group, the levels of da and 5-ht in the prefrontal cortex of the low, medium and high dose groups were significantly increased, and showed a dose-dependent effect (p<0.05). |
2020-10-01 |
2023-08-13 |
mouse |
| Zheng Gu, Liujie Chu, Yaqiong Ha. Therapeutic effect of resveratrol on mice with depression. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30936978. |
resveratrol can significantly increase the levels of neurotransmitters da and 5-ht in the prefrontal cortex and increase the expression of npy in the brain, which can play an antagonistic role in depression. |
2020-10-01 |
2023-08-13 |
mouse |
| Arnauld Belmer, Kate Beecher, Angela Jacques, Omkar L Patkar, Florian Sicherre, Selena E Bartlet. Axonal Non-segregation of the Vesicular Glutamate Transporter VGLUT3 Within Serotonergic Projections in the Mouse Forebrain. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31133811. |
therefore, we combined immunohistochemistry, high resolution confocal imaging, and 3d-reconstruction techniques to map and quantify the distribution of vglut3 immunoreactive boutons within 5-ht vs. sert-positive axons in various regions of the mouse forebrain, including the prefrontal cortex, nucleus accumbens core and shell, bed nucleus of the stria terminalis, dorsal striatum, lateral septum, basolateral and central amygdala, and hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Hirotsugu Azechi, Kōsuke Hakamada, Takanobu Yamamot. A new inbred strain of Fawn-Hooded rats demonstrates mania-like behavioural and monoaminergic abnormalities. IBRO reports. vol 7. 2020-10-01. PMID:31763490. |
serotonin and noradrenaline levels were low in the prefrontal cortex and the hippocampus of fh/hamslc rats, but high serotonin turnover was observed in the prefrontal cortex, hippocampus, and striatum. |
2020-10-01 |
2023-08-13 |
rat |
| Yuan Hu, Yu-Nin Wang, Gang-Qiang Zhang, Xian-Zhe Dong, Wan-Wan Liu, Ping Li. Gan-Dan-Liang-Yi-Tang alleviates p-chlorophenylalanine-induced insomnia through modification of the serotonergic and immune system. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882122. |
gdlyt was also able to alleviate insomnia induced by pcpa in the rodent models, and increased 5-hydroxytryptamine levels in the prefrontal cortex, hippocampus, hypothalamus and corpus striatum of pcpa-treated rats. |
2020-09-30 |
2023-08-13 |
mouse |
| Claire N J Meunier, Pascal Chameau, Philippe M Fossie. Modulation of Synaptic Plasticity in the Cortex Needs to Understand All the Players. Frontiers in synaptic neuroscience. vol 9. 2020-09-30. PMID:28203201. |
we illustrate our purpose by recent findings that demonstrate that 5-ht and da cooperate to regulate the plasticity of excitatory and inhibitory synapses targeting layer 5 pyramidal neurons (l5pyns) of the pfc and to fine tune the e/i balance. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jianguo Li, Luwen Hou, Cui Wang, Xueyang Jia, Xuemei Qin, Changxin W. Short Term Intrarectal Administration of Sodium Propionate Induces Antidepressant-Like Effects in Rats Exposed to Chronic Unpredictable Mild Stress. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30319461. |
the antidepressant-like effects of nap were correlated with differential rescue of neurotransmitters in the prefrontal cortex, which may be achieved through the reduction of catabolism of noradrenaline, tryptophan and dopamine, rather than serotonin. |
2020-09-30 |
2023-08-13 |
human |
| Hui Li, Tong Wang, Cuige Shi, Yutao Yang, Xiaoxiao Li, Yan Wu, Zhi-Qing David X. Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30487761. |
inhibition of galr1 in pfc alleviates depressive-like behaviors in postpartum depression rat model by upregulating creb-bndf and 5-ht levels. |
2020-09-30 |
2023-08-13 |
rat |
| Hui Li, Tong Wang, Cuige Shi, Yutao Yang, Xiaoxiao Li, Yan Wu, Zhi-Qing David X. Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30487761. |
moreover, western blot and hplc assays demonstrated that the downregulation of creb-bdnf signaling and 5-ht levels in the pfc of ppd rats were reversed after galr1-sirna injection. |
2020-09-30 |
2023-08-13 |
rat |
| Hui Li, Tong Wang, Cuige Shi, Yutao Yang, Xiaoxiao Li, Yan Wu, Zhi-Qing David X. Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30487761. |
these comprehensive results suggest that the knock down of galr1 in pfc alleviates depressive-like behaviors and reverse downregulation of creb-bdnf and 5-ht levels in ppd rat model. |
2020-09-30 |
2023-08-13 |
rat |
| Héctor González-Pardo, Jorge L Arias, Eneritz Gómez-Lázaro, Isabel López Taboada, Nélida M Conej. Sex-Specific Effects of Early Life Stress on Brain Mitochondrial Function, Monoamine Levels and Neuroinflammation. Brain sciences. vol 10. issue 7. 2020-09-28. PMID:32674298. |
in addition, ms males had lower serotonin levels and increased serotonin turnover in the prefrontal cortex and the hippocampus. |
2020-09-28 |
2023-08-13 |
rat |