| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanli Zhang, Kai Fan, Yanna Liu, Gang Liu, Xiaohan Yang, Jianmei M. Cathepsin C Aggravates Neuroinflammation Involved in Disturbances of Behaviour and Neurochemistry in Acute and Chronic Stress-Induced Murine Model of Depression. Neurochemical research. vol 43. issue 1. 2018-08-16. PMID:28623605. |
the results showed that cat c overexpression (cat c oe) promoted peripheral and central inflammatory response with significantly increased tnfα, il-1β and il-6 in serum, hippocampus and prefrontal cortex, and resultant upregulation of ido and downregulation of 5ht expression in brain, and thereby aggravated depression-like behaviours accessed by open field test, forced swim test and tail suspension test. |
2018-08-16 |
2023-08-13 |
mouse |
| Mary Gemmel, Nikolaos Kokras, Christina Dalla, Jodi L Pawlusk. Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring. Neuropharmacology. vol 128. 2018-07-13. PMID:29024676. |
perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-ht in the pfc, but maternal stress has enduring effects on mpfc synaptic structure in offspring. |
2018-07-13 |
2023-08-13 |
rat |
| Mary Gemmel, Nikolaos Kokras, Christina Dalla, Jodi L Pawlusk. Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring. Neuropharmacology. vol 128. 2018-07-13. PMID:29024676. |
perinatal fluoxetine prevented the effects of maternal stress on 5-ht levels and 5-ht turnover ratio in the pfc of pre-adolescent offspring, particularly in females. |
2018-07-13 |
2023-08-13 |
rat |
| N Kokras, N Pastromas, D Papasava, C de Bournonville, C A Cornil, C Dall. Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats. Psychoneuroendocrinology. vol 87. 2018-07-13. PMID:29054014. |
the hippocampus and prefrontal cortex (pfc) were analyzed for monoamine (noradrenaline, dopamine and serotonin), as well as amino acid (gaba, glutamate, glycine, taurine, alanine and histidine) levels. |
2018-07-13 |
2023-08-13 |
human |
| Zheng-Wu Peng, Fen Xue, Cui-Hong Zhou, Rui-Guo Zhang, Ying Wang, Ling Liu, Han-Fei Sang, Hua-Ning Wang, Qing-Rong Ta. Repetitive transcranial magnetic stimulation inhibits Sirt1/MAO-A signaling in the prefrontal cortex in a rat model of depression and cortex-derived astrocytes. Molecular and cellular biochemistry. vol 442. issue 1-2. 2018-07-12. PMID:28948423. |
here, we aimed to assess the effect of rtms with different parameters (1/5/10 hz, 0.84/1.26 t) on the depressive-like behaviors, 5-hydroxytryptamine (5-ht), 5-hiaa (5-hydroxyindoleacetic acid) and da and ne levels, and monoamine oxidase a (mao-a) activity in chronic unpredictable stress-treated rats, along with the expression of sirtuin 1 (sirt1) and mao-a in the prefrontal cortex (pfc) and cortex-derived astrocytes from new-born rats. |
2018-07-12 |
2023-08-13 |
rat |
| Zheng-Wu Peng, Fen Xue, Cui-Hong Zhou, Rui-Guo Zhang, Ying Wang, Ling Liu, Han-Fei Sang, Hua-Ning Wang, Qing-Rong Ta. Repetitive transcranial magnetic stimulation inhibits Sirt1/MAO-A signaling in the prefrontal cortex in a rat model of depression and cortex-derived astrocytes. Molecular and cellular biochemistry. vol 442. issue 1-2. 2018-07-12. PMID:28948423. |
we found that rtms treatment (5/10 hz, 0.84/1.26 t) ameliorated depressive-like behaviors, increased 5-ht, da and ne levels, decreased the 5-hiaa level and sirt1 and mao-a expression, and reduced mao-a activity in the pfc. |
2018-07-12 |
2023-08-13 |
rat |
| Yuan Liu, Dexiang Liu, Jingjing Xu, Hong Jiang, Fang Pa. Early adolescent stress-induced changes in prefrontal cortex miRNA-135a and hippocampal miRNA-16 in male rats. Developmental psychobiology. vol 59. issue 8. 2018-07-02. PMID:28944448. |
mirna-135a in the prefrontal cortex (pfc) and mirna-16 in the hippocampus (hip) are closely related to the 5-ht neurotransmitter system. |
2018-07-02 |
2023-08-13 |
rat |
| Patrícia P Silveira, Irina Pokhvisneva, Carine Parent, Shirong Cai, Anu Sathyan Sathyapalan Rema, Birit F P Broekman, Anne Rifkin-Graboi, Michael Pluess, Kieran J O'Donnell, Michael J Meane. Cumulative prenatal exposure to adversity reveals associations with a broad range of neurodevelopmental outcomes that are moderated by a novel, biologically informed polygenetic score based on the serotonin transporter solute carrier family C6, member 4 (SLC6A4) gene expression. Development and psychopathology. vol 29. issue 5. 2018-06-06. PMID:29162172. |
a genetic score based on genes coexpressed with the serotonin transporter in the amygdala, hippocampus, and prefrontal cortex during prenatal life was constructed with an emphasis on functionally relevant single nucleotide polymorphisms, that is, expression quantitative trait loci. |
2018-06-06 |
2023-08-13 |
Not clear |
| Grazyna Rajkowska, Gouri Mahajan, Beata Legutko, Lavanya Challagundla, Michael Griswold, Paul R Albert, Mireille Daigle, Jose J Miguel-Hidalgo, Mark C Austin, Randy D Blakely, David C Steffens, Craig A Stockmeie. Length of axons expressing the serotonin transporter in orbitofrontal cortex is lower with age in depression. Neuroscience. vol 359. 2018-04-30. PMID:28711621. |
studies of major depressive disorder (mdd) in postmortem brain tissue report enhanced binding to inhibitory serotonin-1a autoreceptors in midbrain dorsal raphe and reductions in length of axons expressing the serotonin transporter (sert) in dorsolateral prefrontal cortex. |
2018-04-30 |
2023-08-13 |
human |
| Yuan Du, Haiyue Liang, Leiming Zhang, Fenghua F. Administration of Huperzine A exerts antidepressant-like activity in a rat model of post-stroke depression. Pharmacology, biochemistry, and behavior. vol 158. 2018-03-26. PMID:28583576. |
levels of norepinephrine (ne), dopamine (da), and 5-hydroxytryptamine (5-ht) in the hippocampus and prefrontal cortex were assayed by high performance liquid chromatography. |
2018-03-26 |
2023-08-13 |
rat |
| Noemí Santana, Francesc Artiga. Expression of Serotonin2C Receptors in Pyramidal and GABAergic Neurons of Rat Prefrontal Cortex: A Comparison with Striatum. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 6. 2018-03-19. PMID:27252352. |
the prefrontal cortex (pfc) is enriched in several serotonin receptors, including 5-ht1a-r, 5-ht2a-r, and 5-ht3-r. |
2018-03-19 |
2023-08-13 |
rat |
| Sofia Raitsin, Junchao Tong, Stephen Kish, Xin Xu, Lilia Magomedova, Carolyn Cummins, Ana C Andreazza, Gustavo Scola, Glen Baker, Jeffrey H Meye. Subchronic glucocorticoids, glutathione depletion and a postpartum model elevate monoamine oxidase a activity in the prefrontal cortex of rats. Brain research. vol 1666. 2018-03-13. PMID:28435083. |
young adult rats exposed chronically to the synthetic glucocorticoid dexamethasone at 0, 0.05, 0.5, and 2.0mg/kg/day (osmotic minipumps) for eight days showed significant dose-dependent increases in activities of mao-a in pfc (+17%, p<0.001) and acc (+9%, p<0.01) and mao-b in pfc (+14%, p<0.001) and increased serotonin turnover in the pfc (+31%, p<0.01), not accounted for by dexamethasone-induced changes in serotonin levels, since neither serotonin depletion nor supplementation affected mao-a activity. |
2018-03-13 |
2023-08-13 |
human |
| Patrick Eisner, Martin Klasen, Dhana Wolf, Klaus Zerres, Thomas Eggermann, Albrecht Eisert, Mikhail Zvyagintsev, Pegah Sarkheil, Krystyna A Mathiak, Florian Zepf, Klaus Mathia. Cortico-limbic connectivity in MAOA-L carriers is vulnerable to acute tryptophan depletion. Human brain mapping. vol 38. issue 3. 2018-02-13. PMID:27935229. |
a cortico-limbic circuit involving the prefrontal cortex (pfc) and the amygdala is central to the suppression of aggressive impulses and is modulated by serotonin (5-ht). |
2018-02-13 |
2023-08-13 |
Not clear |
| Ernest Dallé, Willie M U Daniels, Musa V Mabandl. Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory. Brain research bulletin. vol 132. 2018-02-09. PMID:28549887. |
in the present study, we looked at whether exposure to early life stress reduces da and serotonin (5-ht) concentration in the pfc thus leading to enhanced cognitive impairment in a parkinsonian rat model. |
2018-02-09 |
2023-08-13 |
rat |
| Ernest Dallé, Willie M U Daniels, Musa V Mabandl. Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory. Brain research bulletin. vol 132. 2018-02-09. PMID:28549887. |
a 6-ohda lesion effect was evidenced by impairment in the cylinder test as well as decreased da and 5-ht concentration in the pfc. |
2018-02-09 |
2023-08-13 |
rat |
| Ernest Dallé, Willie M U Daniels, Musa V Mabandl. Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory. Brain research bulletin. vol 132. 2018-02-09. PMID:28549887. |
this study suggests that da and 5-ht signaling in the pfc are responsive to fm and may reduce stress-induced cognitive impairment in pd. |
2018-02-09 |
2023-08-13 |
rat |
| Matheus Teixeira Rossignoli, Cleiton Lopes-Aguiar, Rafael Naime Ruggiero, Raquel Araujo Do Val da Silva, Lezio Soares Bueno-Junior, Ludmyla Kandratavicius, José Eduardo Peixoto-Santos, José Alexandre Crippa, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, Raphael Escorsim Szawka, Janete Anselmo-Franci, João Pereira Leite, Rodrigo Neves Romcy-Pereir. Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits. Neuroscience. vol 350. 2018-02-06. PMID:28344069. |
neurochemical and cellular correlates of the cbd treatment were evaluated by the quantification of extracellular levels of dopamine (da), serotonin, and their metabolites in the pfc and by measuring the cellular expression of activity-dependent transcription factors in cortical and limbic regions. |
2018-02-06 |
2023-08-13 |
Not clear |
| Huiyan Shi, Chenzhi Hou, Liqiang Gu, Hang Xing, Meiyu Zhang, Longshan Zhao, Kaishun Bi, Xiaohui Che. Investigation of the protective effect of Paeonia lactiflora on Semen Strychni-induced neurotoxicity based on monitoring nine potential neurotoxicity biomarkers in rat serum and brain tissue. Metabolic brain disease. vol 32. issue 1. 2018-01-31. PMID:27521025. |
a sensitive liquid chromatography-tandem mass spectrometry method was developed and validated to monitor serotonin, tryptophan, dopamine, tyrosine and glutamate in serum and five brain regions (prefrontal cortex, hippocampus, striatum, cerebellum and hypothalamus). |
2018-01-31 |
2023-08-13 |
rat |
| Helen de Morais, Camila P de Souza, Luisa M da Silva, Daniele M Ferreira, Cristiane Hatsuko Baggio, Ana Carolina Vanvossen, Milene Cristina de Carvalho, José Eduardo da Silva-Santos, Leandro José Bertoglio, Joice M Cunha, Janaina M Zanovel. Anandamide reverses depressive-like behavior, neurochemical abnormalities and oxidative-stress parameters in streptozotocin-diabetic rats: Role of CB1 receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 10. 2018-01-29. PMID:27544303. |
oxidative stress parameters, cb1 receptor expression and serotonin (5-ht) and noradrenaline levels in the hippocampus (hip) and prefrontal cortex (pfc) were also performed. |
2018-01-29 |
2023-08-13 |
rat |
| Cristina Miguelez, Sylvia Navailles, Claire Delaville, Loïse Marquis, Mélanie Lagière, Abdelhamid Benazzouz, Luisa Ugedo, Philippe De Deurwaerdèr. L-DOPA elicits non-vesicular releases of serotonin and dopamine in hemiparkinsonian rats in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 8. 2018-01-23. PMID:27234917. |
non-homogeneously decreased extracellular serotonin levels in the striatum, substantia nigra pars reticulata, hippocampus and prefrontal cortex and homogenously serotonin tissue content in the striatum, cortex and cerebellum. |
2018-01-23 |
2023-08-13 |
rat |