All Relations between prefrontal cortex and serotonin

Publication Sentence Publish Date Extraction Date Species
Cristina Miguelez, Sylvia Navailles, Claire Delaville, Loïse Marquis, Mélanie Lagière, Abdelhamid Benazzouz, Luisa Ugedo, Philippe De Deurwaerdèr. L-DOPA elicits non-vesicular releases of serotonin and dopamine in hemiparkinsonian rats in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 8. 2018-01-23. PMID:27234917. when focusing on serotonin release in the prefrontal cortex and the hippocampus, we found that l-dopa (12 or 100mg/kg) enhanced serotonin extracellular levels in both regions upon ca(2+) removal. 2018-01-23 2023-08-13 rat
Marie-Line Reynaert, Jordan Marrocco, Jérôme Mairesse, Luana Lionetto, Maurizio Simmaco, Lucie Deruyter, Delphine Allorge, Anna Moles, Anna Pittaluga, Stefania Maccari, Sara Morley-Fletcher, Gilles Van Camp, Ferdinando Nicolett. Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner. Addiction biology. vol 21. issue 6. 2018-01-16. PMID:26011513. male prs rats also show increases in plasma dihydrotestosterone (dht) levels and dopamine (da) levels in the nucleus accumbens (nac), and reductions in 5-hydroxytryptamine (5-ht) levels in the nac and prefrontal cortex (pfc). 2018-01-16 2023-08-13 rat
Qian Zhe, Wang Sulei, Tao Weiwei, Long Hongyan, Wang Jianwe. Effects of Jiaotaiwan on depressive-like behavior in mice after lipopolysaccharide administration. Metabolic brain disease. vol 32. issue 2. 2018-01-05. PMID:27796565. the 5-hydroxytryptamine (5-ht) and nor-epinephrine (ne) levels in prefrontal cortex were determined by uplc-ms. 2018-01-05 2023-08-13 mouse
Yurii A Zolotarev, Georgii I Kovalev, Natalya V Kost, Margarita E Voevodina, Oleg Y Sokolov, Alexander K Dadayan, Evgenii A Kondrakhin, Ekaterina V Vasileva, Anna P Bogachuk, Vyacheslav N Azev, Valery M Lipkin, Nikolai F Myasoedo. Anxiolytic activity of the neuroprotective peptide HLDF-6 and its effects on brain neurotransmitter systems in BALB/c and C57BL/6 mice. Journal of psychopharmacology (Oxford, England). vol 30. issue 9. 2018-01-04. PMID:27464742. the mechanism of the specific anxiolytic activity of hldf-6-amide may include its action on the nmda-glutamatergic receptor system of the hippocampus and on serotonin 5-ht2a-receptors in the prefrontal cortex. 2018-01-04 2023-08-13 mouse
A Chiavaroli, L Recinella, C Ferrante, S Martinotti, M Vacca, L Brunetti, G Orlando, S Leon. Effects of central fibroblast growth factor 21 and irisin in anxiety-like behavior. Journal of biological regulators and homeostatic agents. vol 31. issue 3. 2017-12-14. PMID:28890831. prefrontal cortex levels of norepinephrine (ne), dopamine (da) and serotonin (5-hydroxytryptamine, 5-ht) and the gene expression of catechol-o-methyltransferase (comt), dopamine transport (dat) and tyrosine hydroxylase (th), were measured by high performance liquid chromatography (hplc) analysis and real-time reverse transcription polymerase chain reaction (rt-pcr). 2017-12-14 2023-08-13 rat
Jon Stefansson, Andreas Chatzittofis, Peter Nordström, Stefan Arver, Marie Åsberg, Jussi Jokine. CSF and plasma testosterone in attempted suicide. Psychoneuroendocrinology. vol 74. 2017-12-08. PMID:27567115. dual-hormone serotonergic theory on human impulsive aggression implies high testosterone/cortisol ratio acting on the amygdala and low serotonin in the prefrontal cortex. 2017-12-08 2023-08-13 human
Ana Paula Pesarico, Gláubia Sartori, César A Brüning, Anderson C Mantovani, Thiago Duarte, Gilson Zeni, Cristina Wayne Nogueir. A novel isoquinoline compound abolishes chronic unpredictable mild stress-induced depressive-like behavior in mice. Behavioural brain research. vol 307. 2017-11-28. PMID:27036647. the synaptosomal [(3)h] serotonin (5-ht) uptake, nuclear factor (nf)-κb, tyrosine kinase receptor (trkb) and pro-brain-derived neurotrophic factor (bdnf) levels were determined in the mouse prefrontal cortex. 2017-11-28 2023-08-13 mouse
Alvaro L Garcia-Garcia, Qingyuan Meng, Sarah Canetta, Alain M Gardier, Bruno P Guiard, Christoph Kellendonk, Alex Dranovsky, E David Leonard. Serotonin Signaling through Prefrontal Cortex 5-HT Cell reports. vol 18. issue 5. 2017-11-28. PMID:28147271. serotonin signaling through prefrontal cortex 5-ht lifelong homeostatic setpoints for mood-related behaviors emerge during adolescence. 2017-11-28 2023-08-13 Not clear
Koji Masuda, Mari Nakanishi, Kana Okamoto, Chiwa Kawashima, Harumi Oshita, Ayako Inoue, Fuku Takita, Toshihiko Izumi, Yoshinobu Ishitobi, Haruka Higuma, Masayuki Kanehisa, Taiga Ninomiya, Yoshinori Tanaka, Jotaro Akiyosh. Different functioning of prefrontal cortex predicts treatment response after a selective serotonin reuptake inhibitor treatment in patients with major depression. Journal of affective disorders. vol 214. 2017-11-27. PMID:28266320. different functioning of prefrontal cortex predicts treatment response after a selective serotonin reuptake inhibitor treatment in patients with major depression. 2017-11-27 2023-08-13 Not clear
Marina A Gruden, Tatiana V Davydova, Chao Wang, Victor B Narkevich, Valentina G Fomina, Vladimir S Kudrin, Ludmilla A Morozova-Roche, Robert D E Sewel. The misfolded pro-inflammatory protein S100A9 disrupts memory via neurochemical remodelling instigating an Alzheimer's disease-like cognitive deficit. Behavioural brain research. vol 306. 2017-11-17. PMID:26965570. native s100a9 did not modify memory task performance even though it generated a general and consistent decrease in monoamine levels (da, 5-ht and na) and increased metabolic marker ratios of da and 5-ht turnover (dopac/da, hva/da and 5-hiaa) in the prefrontal cortex. 2017-11-17 2023-08-13 mouse
T Cardozo, E Shmelkov, K Felsovalyi, J Swetnam, T Butler, D Malaspina, S V Shmelko. Chemistry-based molecular signature underlying the atypia of clozapine. Translational psychiatry. vol 7. issue 2. 2017-11-16. PMID:28221369. our results implicate dopamine d4 receptors in the pineal gland and muscarinic acetylcholine m1 (chrm1) and m3 (chrm3) receptors in the prefrontal cortex (pfc) as significant and unique to clozapine, whereas serotonin receptors 5-ht 2017-11-16 2023-08-13 Not clear
Francesca Zoratto, Emilia Romano, Esterina Pascale, Mariangela Pucci, Anastasia Falconi, Bernardo Dell'Osso, Mauro Maccarrone, Giovanni Laviola, Claudio D'Addario, Walter Adrian. Down-regulation of serotonin and dopamine transporter genes in individual rats expressing a gambling-prone profile: A possible role for epigenetic mechanisms. Neuroscience. vol 340. 2017-11-06. PMID:27789384. a selective down-regulation of i) serotonin transporter in prefrontal cortex, ii) tyrosine hydroxylase in ventral striatum, iii) dopamine transporter in lymphocytes was evidenced in "gambler" vs "non-gambler" rats. 2017-11-06 2023-08-13 rat
Francesca Zoratto, Emilia Romano, Esterina Pascale, Mariangela Pucci, Anastasia Falconi, Bernardo Dell'Osso, Mauro Maccarrone, Giovanni Laviola, Claudio D'Addario, Walter Adrian. Down-regulation of serotonin and dopamine transporter genes in individual rats expressing a gambling-prone profile: A possible role for epigenetic mechanisms. Neuroscience. vol 340. 2017-11-06. PMID:27789384. a consistent increase of dna methylation, in one specific cpg site at serotonin transporter gene, was evident in prefrontal cortex of "gambler" rats. 2017-11-06 2023-08-13 rat
Hariom Kumar, Bhupesh Sharm. Memantine ameliorates autistic behavior, biochemistry & blood brain barrier impairments in rats. Brain research bulletin. vol 124. 2017-10-26. PMID:27034117. animals with prenatal valproic acid have shown the reduction in social interaction (three-chamber social behavior apparatus), spontaneous alternation (y-maze), exploratory activity (hole board test), intestinal motility, serotonin levels (both in prefrontal cortex and ileum) and prefrontal cortex mitochondrial complex activity (complex i, ii, iv). 2017-10-26 2023-08-13 rat
Hariom Kumar, Bhupesh Sharm. Memantine ameliorates autistic behavior, biochemistry & blood brain barrier impairments in rats. Brain research bulletin. vol 124. 2017-10-26. PMID:27034117. treatment with memantine has significantly attenuated prenatal valproic acid-induced reduction in social interaction, spontaneous alteration, exploratory activity intestinal motility, serotonin levels and prefrontal cortex mitochondrial complex activity. 2017-10-26 2023-08-13 rat
Michael K Tian, Eric F Schmidt, Evelyn K Lamb. Serotonergic Suppression of Mouse Prefrontal Circuits Implicated in Task Attention. eNeuro. vol 3. issue 5. 2017-10-26. PMID:27844060. layer 6 (l6) pyramidal neurons of prefrontal cortex play an important role in attention and express 5-ht receptors, but the serotonergic modulation of this layer and its excitatory output is not known. 2017-10-26 2023-08-13 mouse
Sarah A Jablonski, Devon L Graham, Charles V Vorhees, Michael T William. Effects of Neonatal Methamphetamine and Stress on Brain Monoamines and Corticosterone in Preweanling Rats. Neurotoxicity research. vol 31. issue 2. 2017-10-10. PMID:27817108. separate litters were assessed at p15 or p20 for organ weights (adrenals, spleen, thymus); corticosterone; and monoamine assessments (dopamine, serotonin, norepinephrine) and their metabolites within the neostriatum, hippocampus, and prefrontal cortex. 2017-10-10 2023-08-13 rat
Stefan Fritze, Rainer Spanagel, Hamid R Noor. Adaptive dynamics of the 5-HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta-analysis. Journal of neurochemistry. vol 142. issue 5. 2017-09-21. PMID:28653748. however, in hippocampus, prefrontal cortex, nucleus accumbens, and ventral tegmental area we found increased 5-ht levels within the first 3 days of ssri administration. 2017-09-21 2023-08-13 rat
Mary Gemmel, Ine Rayen, Eva van Donkelaar, Tiffany Loftus, Harry W Steinbusch, Nikolaos Kokras, Christina Dalla, Jodi L Pawlusk. Gestational stress and fluoxetine treatment differentially affect plasticity, methylation and serotonin levels in the PFC and hippocampus of rat dams. Neuroscience. vol 327. 2017-08-31. PMID:27060483. gestational stress and fluoxetine treatment differentially affect plasticity, methylation and serotonin levels in the pfc and hippocampus of rat dams. 2017-08-31 2023-08-13 rat
Christoffer Bundgaard, Liliana P Montezinho, Neil Anderson, Christian Thomsen, Arne Mør. Selegiline induces a wake promoting effect in rats which is related to formation of its active metabolites. Pharmacology, biochemistry, and behavior. vol 150-151. 2017-08-31. PMID:27984094. furthermore, selegiline (5mg/kg) caused a significant increase of extracellular levels of da (250%) and na (200%), but not of 5-ht, in the rat prefrontal cortex. 2017-08-31 2023-08-13 rat