| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana F Almeida-Santos, Fabricio A Moreira, Francisco S Guimaraes, Daniele C Aguia. 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. Journal of psychopharmacology (Oxford, England). vol 31. issue 6. 2018-03-22. PMID:28440729. |
moreover, immunofluorescence microscopy revealed co-expression of metabotropic glutamate receptor type 5 and diacylglycerol lipase-α in several neurons in slices from the ventromedial prefrontal cortex. |
2018-03-22 |
2023-08-13 |
rat |
| Branislava Ćurčić-Blake, Leonie Bais, Anita Sibeijn-Kuiper, Hendrika Maria Pijnenborg, Henderikus Knegtering, Edith Liemburg, André Alema. Glutamate in dorsolateral prefrontal cortex and auditory verbal hallucinations in patients with schizophrenia: A Progress in neuro-psychopharmacology & biological psychiatry. vol 78. 2018-03-09. PMID:28546056. |
glutamate in dorsolateral prefrontal cortex and auditory verbal hallucinations in patients with schizophrenia: a glutamatergic models of psychosis propose that dysfunction of n-methyl-d-aspartate (nmda) receptors, and associated excess of glutamate, may underlie psychotic experiences in people with schizophrenia. |
2018-03-09 |
2023-08-13 |
Not clear |
| Huiyan Shi, Chenzhi Hou, Liqiang Gu, Hang Xing, Meiyu Zhang, Longshan Zhao, Kaishun Bi, Xiaohui Che. Investigation of the protective effect of Paeonia lactiflora on Semen Strychni-induced neurotoxicity based on monitoring nine potential neurotoxicity biomarkers in rat serum and brain tissue. Metabolic brain disease. vol 32. issue 1. 2018-01-31. PMID:27521025. |
a sensitive liquid chromatography-tandem mass spectrometry method was developed and validated to monitor serotonin, tryptophan, dopamine, tyrosine and glutamate in serum and five brain regions (prefrontal cortex, hippocampus, striatum, cerebellum and hypothalamus). |
2018-01-31 |
2023-08-13 |
rat |
| Brandy L Schneider, Farhad Ghoddoussi, Jennifer L Charlton, Robert J Kohler, Matthew P Galloway, Shane A Perrine, Alana C Cont. Increased Cortical Gamma-Aminobutyric Acid Precedes Incomplete Extinction of Conditioned Fear and Increased Hippocampal Excitatory Tone in a Mouse Model of Mild Traumatic Brain Injury. Journal of neurotrauma. vol 33. issue 17. 2018-01-30. PMID:26529240. |
using proton magnetic resonance spectroscopy ex vivo, we examined pfc, amyg, and hc levels of gamma-aminobutyric acid (gaba) and glutamate as surrogate measures of inhibitory and excitatory neurotransmission, respectively. |
2018-01-30 |
2023-08-13 |
mouse |
| Fabrice Jollant, Stéphane Richard-Devantoy, Yang Ding, Gustavo Turecki, Antoine Bechara, Jamie Nea. Prefrontal inositol levels and implicit decision-making in healthy individuals and depressed patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 8. 2018-01-23. PMID:27342631. |
we used 3t proton magnetic resonance spectroscopy to measure in vivo glutamate, gaba, n-acetyl-aspartate (naa), and myo-inositol levels at rest in the right dorsal prefrontal cortex of 54 participants, comprising 24 unmedicated depressed patients and 30 healthy individuals. |
2018-01-23 |
2023-08-13 |
human |
| Christopher R Dorsett, Jennifer L McGuire, Tracy L Niedzielko, Erica A K DePasquale, Jaroslaw Meller, Candace L Floyd, Robert E McCullumsmit. Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression. Journal of neurotrauma. vol 34. issue 1. 2018-01-12. PMID:27312729. |
taken together, our data suggest diminished activity of glutamate transporters in the prefrontal cortex, with no changes in protein expression of the primary glutamate transporter glt-1, and global alterations in signaling networks that include serine-threonine kinases that are known modulators of glutamate transport activity. |
2018-01-12 |
2023-08-13 |
rat |
| Ya Bin Wei, Philippe A Melas, J Carlos Villaescusa, Jia Jia Liu, Ning Xu, Søren Hofman Christiansen, Heidi Elbrønd-Bek, David Paul Drucker Woldbye, Gregers Wegener, Aleksander A Mathé, Catharina Lavebrat. MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro. The international journal of neuropsychopharmacology. vol 19. issue 12. 2018-01-08. PMID:27507301. |
microrna 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter slc1a1 (eaat3) in vitro. |
2018-01-08 |
2023-08-13 |
Not clear |
| Marc J Dubin, Xiangling Mao, Samprit Banerjee, Zachary Goodman, Kyle A B Lapidus, Guoxin Kang, Conor Liston, Dikoma C Shung. Elevated prefrontal cortex GABA in patients with major depressive disorder after TMS treatment measured with proton magnetic resonance spectroscopy. Journal of psychiatry & neuroscience : JPN. vol 41. issue 3. 2018-01-04. PMID:26900793. |
we assessed the effect of 10-hz rtms over the left dorsolateral prefrontal cortex (dlpfc) of patients with major depressive disorder on the levels of medial prefrontal cortex (mpfc) γ-aminobutyric acid (gaba) and the combined resonance of glutamate and glutamine (glx) as assessed in vivo with proton magnetic resonance spectroscopy ((1)h mrs). |
2018-01-04 |
2023-08-13 |
Not clear |
| Isabella Panaccione, Luisa Iacovelli, Luigi di Nuzzo, Francesca Nardecchia, Gianluca Mauro, Delfina Janiri, Antonio De Blasi, Gabriele Sani, Ferdinando Nicoletti, Rosamaria Orland. Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. Pharmacological research. vol 117. 2017-12-27. PMID:27890550. |
sleep deprived rats showed a substantial reduction in type-2 metabotropic glutamate (mglu2) receptors mrna and protein levels in the hippocampus, but not in the prefrontal cortex or corpus striatum, as compared to both groups of control rats. |
2017-12-27 |
2023-08-13 |
rat |
| Giulia Treccani, Kristian Gaarn du Jardin, Gregers Wegener, Heidi Kaastrup Mülle. Differential expression of postsynaptic NMDA and AMPA receptor subunits in the hippocampus and prefrontal cortex of the flinders sensitive line rat model of depression. Synapse (New York, N.Y.). vol 70. issue 11. 2017-12-22. PMID:27262028. |
to gain insight into how signaling through glutamate receptors may be altered in the fsl rats, we investigated the expression and phosphorylation of ampa and nmda receptor subunits in an enriched postsynaptic fraction of the hippocampus and prefrontal cortex. |
2017-12-22 |
2023-08-13 |
rat |
| Chadi G Abdallah, Thomas G Adams, Benjamin Kelmendi, Irina Esterlis, Gerard Sanacora, John H Krysta. KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS. Depression and anxiety. vol 33. issue 8. 2017-12-20. PMID:27062302. |
animal and human research suggest that ketamine's antidepressant effects are mediated by a glutamate surge that leads to a cascade of events that result in synaptogenesis and reversal of the negative effects of chronic stress and depression, particularly within the prefrontal cortex (pfc). |
2017-12-20 |
2023-08-13 |
human |
| Mark A Frye, David J Hinton, Victor M Karpyak, Joanna M Biernacka, Lee J Gunderson, Jennifer Geske, Scott E Feeder, Doo-Sup Choi, John D Por. Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol. Alcoholism, clinical and experimental research. vol 40. issue 8. 2017-12-15. PMID:27439218. |
elevated glutamate levels in the left dorsolateral prefrontal cortex are associated with higher cravings for alcohol. |
2017-12-15 |
2023-08-13 |
Not clear |
| Mark A Frye, David J Hinton, Victor M Karpyak, Joanna M Biernacka, Lee J Gunderson, Jennifer Geske, Scott E Feeder, Doo-Sup Choi, John D Por. Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol. Alcoholism, clinical and experimental research. vol 40. issue 8. 2017-12-15. PMID:27439218. |
in an effort to identify biological correlates of craving, we used proton magnetic resonance spectroscopy (1h-mrs) to investigate the correlation between craving and glutamate levels in the left dorsolateral prefrontal cortex (ldlpfc) of patients with aud. |
2017-12-15 |
2023-08-13 |
Not clear |
| Derek Lupinsky, Luc Moquin, Alain Gratto. Interhemispheric regulation of the rat medial prefrontal cortical glutamate stress response: role of local GABA- and dopamine-sensitive mechanisms. Psychopharmacology. vol 234. issue 3. 2017-12-13. PMID:27822602. |
we previously reported that stressors increase medial prefrontal cortex (pfc) glutamate (glu) levels as a result of activating callosal neurons located in the opposite hemisphere and that this pfc glu stress response is regulated by glu-, dopamine- (da-), and gaba-sensitive mechanisms (lupinsky et al. |
2017-12-13 |
2023-08-13 |
rat |
| Alaa M Hammad, Fawaz Alasmari, Yusuf S Althobaiti, Youssef Sar. Modulatory effects of Ampicillin/Sulbactam on glial glutamate transporters and metabotropic glutamate receptor 1 as well as reinstatement to cocaine-seeking behavior. Behavioural brain research. vol 332. 2017-12-12. PMID:28624317. |
we also investigated the effects of amp/sul on the expression of glial glutamate transporters and metabotropic glutamate receptor 1 (mglur1) in the nucleus accumbens (nac) core and shell and the dorsomedial prefrontal cortex (dmpfc). |
2017-12-12 |
2023-08-13 |
rat |
| Francesca R Farina, Sean Commin. Differential expression of immediate early genes Zif268 and c-Fos in the hippocampus and prefrontal cortex following spatial learning and glutamate receptor antagonism. Behavioural brain research. vol 307. 2017-11-28. PMID:27071329. |
differential expression of immediate early genes zif268 and c-fos in the hippocampus and prefrontal cortex following spatial learning and glutamate receptor antagonism. |
2017-11-28 |
2023-08-13 |
rat |
| D Becker-Krail, A Q Farrand, H A Boger, A Lavi. Effects of fingolimod administration in a genetic model of cognitive deficits. Journal of neuroscience research. vol 95. issue 5. 2017-11-16. PMID:27439747. |
previously, we have shown that mutations in the dtnbp1 gene (encoding dystrobrevin-binding protein 1 [dysbindin-1]) lead to abnormalities in synaptic glutamate release in the prefrontal cortex (pfc) and hippocampus and to cognitive deficits; glutamatergic transmission is important for cortical recurrent excitation that allows information processing in the pfc. |
2017-11-16 |
2023-08-13 |
mouse |
| George F Koob, Nora D Volko. Neurobiology of addiction: a neurocircuitry analysis. The lancet. Psychiatry. vol 3. issue 8. 2017-11-09. PMID:27475769. |
the craving and deficits in executive function in the so-called preoccupation/anticipation stage involve the dysregulation of key afferent projections from the prefrontal cortex and insula, including glutamate, to the basal ganglia and extended amygdala. |
2017-11-09 |
2023-08-13 |
Not clear |
| Xinyu Zhou, Lanxiang Liu, Yuqing Zhang, Juncai Pu, Lining Yang, Chanjuan Zhou, Shuai Yuan, Hanping Zhang, Peng Xi. Metabolomics identifies perturbations in amino acid metabolism in the prefrontal cortex of the learned helplessness rat model of depression. Neuroscience. vol 343. 2017-11-08. PMID:27919695. |
amino acid metabolism, particularly glutamate metabolism, cysteine and methionine metabolism, arginine and proline metabolism, was significantly perturbed in the prefrontal cortex of lh rats. |
2017-11-08 |
2023-08-13 |
rat |
| L C Houtepen, R R Schür, J P Wijnen, V O Boer, M P M Boks, R S Kahn, M Joëls, D W Klomp, C H Vinker. Acute stress effects on GABA and glutamate levels in the prefrontal cortex: A 7T NeuroImage. Clinical. vol 14. 2017-11-07. PMID:28180078. |
acute stress effects on gaba and glutamate levels in the prefrontal cortex: a 7t there is ample evidence that the inhibitory gaba and the excitatory glutamate system are essential for an adequate response to stress. |
2017-11-07 |
2023-08-13 |
human |