| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yelena Gulchina, Song-Jun Xu, Melissa A Snyder, Felice Elefant, Wen-Jun Ga. Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia. Journal of neurochemistry. vol 143. issue 3. 2017-11-02. PMID:28628228. |
glutamate hypofunction has been a prominent hypothesis in the understanding of scz pathology; however, little attention has been given to the nmdar system in the developing pfc in models for scz. |
2017-11-02 |
2023-08-13 |
Not clear |
| Victoria A Mach. Neuro-immune interactions across development: A look at glutamate in the prefrontal cortex. Neuroscience and biobehavioral reviews. vol 71. 2017-10-17. PMID:27593444. |
neuro-immune interactions across development: a look at glutamate in the prefrontal cortex. |
2017-10-17 |
2023-08-13 |
Not clear |
| Brent Myers, Jessica M McKlveen, Rachel Morano, Yvonne M Ulrich-Lai, Matia B Solomon, Steven P Wilson, James P Herma. Vesicular Glutamate Transporter 1 Knockdown in Infralimbic Prefrontal Cortex Augments Neuroendocrine Responses to Chronic Stress in Male Rats. Endocrinology. vol 158. issue 10. 2017-10-16. PMID:28938481. |
vesicular glutamate transporter 1 knockdown in infralimbic prefrontal cortex augments neuroendocrine responses to chronic stress in male rats. |
2017-10-16 |
2023-08-13 |
rat |
| Ismaël Daher, Bérénice Le Dieu-Lugon, Nathalie Dourmap, Matthieu Lecuyer, Lauriane Ramet, Cathy Gomila, Jérôme Ausseil, Stéphane Marret, Philippe Leroux, Vincent Roy, Salah El Mestikawy, Stéphanie Daumas, Bruno Gonzalez, Isabelle Leroux-Nicollet, Carine Clere. Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice. Journal of neuropathology and experimental neurology. vol 76. issue 10. 2017-10-02. PMID:28922852. |
the lesion increased glutamate level at p10 in the prefrontal cortex, which was prevented by mgso4 in males. |
2017-10-02 |
2023-08-13 |
mouse |
| G M I Chowdhury, J Zhang, M Thomas, M Banasr, X Ma, B Pittman, L Bristow, E Schaeffer, R S Duman, D L Rothman, K L Behar, G Sanacor. Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects. Molecular psychiatry. vol 22. issue 1. 2017-09-29. PMID:27067013. |
transiently increased glutamate cycling in rat pfc is associated with rapid onset of antidepressant-like effects. |
2017-09-29 |
2023-08-13 |
rat |
| J Zhao, R W H Verwer, D J van Wamelen, X-R Qi, S-F Gao, P J Lucassen, D F Swaa. Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide. Journal of psychiatric research. vol 82. 2017-09-08. PMID:27450072. |
the expression of various components of the glutamate-glutamine cycle and the neuronal/glial glutamate transporters was determined by qpcr in postmortem prefrontal cortex. |
2017-09-08 |
2023-08-13 |
human |
| D M Bortz, H-Q Wu, R Schwarcz, J P Brun. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. vol 121. 2017-09-05. PMID:28419874. |
oral administration of a specific kynurenic acid synthesis (kat ii) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. |
2017-09-05 |
2023-08-13 |
rat |
| D M Bortz, H-Q Wu, R Schwarcz, J P Brun. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. vol 121. 2017-09-05. PMID:28419874. |
we determined, in adult wistar rats, if the orally available kat ii inhibitor bff816 a) prevents kyna elevations in prefrontal cortex (pfc) after a systemic kynurenine injection and b) reverses the kynurenine-induced attenuation of evoked prefrontal glutamate release caused by stimulation of the nucleus accumbens shell (nacsh). |
2017-09-05 |
2023-08-13 |
rat |
| D M Bortz, H-Q Wu, R Schwarcz, J P Brun. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. vol 121. 2017-09-05. PMID:28419874. |
the two doses of kynurenine reduced evoked glutamate release in pfc (by 43% and 94%, respectively, compared to nmda alone). |
2017-09-05 |
2023-08-13 |
rat |
| D M Bortz, H-Q Wu, R Schwarcz, J P Brun. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. vol 121. 2017-09-05. PMID:28419874. |
attenuated the neosynthesis of kyna and dose-dependently restored nmda-stimulated glutamate release in the pfc (16% and 69%, respectively). |
2017-09-05 |
2023-08-13 |
rat |
| D M Bortz, H-Q Wu, R Schwarcz, J P Brun. Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex. Neuropharmacology. vol 121. 2017-09-05. PMID:28419874. |
the ability to prevent kyna neosynthesis and to normalize evoked glutamate release in pfc justifies further development of kat ii inhibitors for the treatment of cognitive deficits in sz. |
2017-09-05 |
2023-08-13 |
rat |
| Mercedes Erburu, Irene Muñoz-Cobo, Teresa Diaz-Perdigon, Paolo Mellini, Takayoshi Suzuki, Elena Puerta, Rosa M Torder. SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action. Neuropharmacology. vol 117. 2017-08-29. PMID:28185898. |
sirt2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action. |
2017-08-29 |
2023-08-13 |
Not clear |
| Yusuf S Althobaiti, Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Youssef Sar. Effects of repeated high-dose methamphetamine and ceftriaxone post-treatments on tissue content of dopamine and serotonin as well as glutamate and glutamine. Neuroscience letters. vol 634. 2017-08-21. PMID:27702628. |
additionally, meth caused a significant decrease in glutamate and glutamine tissue content in pfc, and this effect was attenuated by cef post-treatment. |
2017-08-21 |
2023-08-13 |
rat |
| Katharina Gapp, Alberto Corcoba, Gretchen van Steenwyk, Isabelle M Mansuy, João Mn Duart. Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 37. issue 7. 2017-08-14. PMID:27604311. |
we found that, relative to controls, early life stress-exposed mice have metabolic alterations consistent with neuronal dysfunction, including reduced concentration of n-acetylaspartate, glutamate and γ-aminobutyrate, in the prefrontal cortex in basal conditions. |
2017-08-14 |
2023-08-13 |
mouse |
| Yan Li, Xin Chen, Rhonda Dzakpasu, Katherine Conan. Dopamine-dependent effects on basal and glutamate stimulated network dynamics in cultured hippocampal neurons. Journal of neurochemistry. vol 140. issue 4. 2017-07-13. PMID:27925199. |
published work suggests that dopamine, a potent modulator of learning and memory, acts on dopamine receptor 1-like dopamine receptors to influence the phosphorylation and trafficking of glutamate receptor subunits, along with long-term potentiation of excitatory synaptic transmission in striatum and prefrontal cortex. |
2017-07-13 |
2023-08-13 |
Not clear |
| D M Bortz, B A Upton, J D Mikkelsen, J P Brun. Positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats. Neuropharmacology. vol 111. 2017-07-11. PMID:27569994. |
positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats. |
2017-07-11 |
2023-08-13 |
rat |
| D M Bortz, B A Upton, J D Mikkelsen, J P Brun. Positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats. Neuropharmacology. vol 111. 2017-07-11. PMID:27569994. |
here we test the hypothesis that pams' potentiation of glutamate release in prefrontal cortex depends upon the level of endogenous cholinergic activity. |
2017-07-11 |
2023-08-13 |
rat |
| Laura Jiménez-Sánchez, Raquel Linge, Leticia Campa, Elsa M Valdizán, Ángel Pazos, Álvaro Díaz, Albert Adel. Behavioral, neurochemical and molecular changes after acute deep brain stimulation of the infralimbic prefrontal cortex. Neuropharmacology. vol 108. 2017-07-07. PMID:27108934. |
in the rat, we have demonstrated that dbs applied to infralimbic (il) cortex elevates the levels of glutamate and monoamines in the prefrontal cortex, and requires the stimulation of cortical α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) glutamate receptors for its antidepressant-like effects. |
2017-07-07 |
2023-08-13 |
rat |
| Robert A Sweet, Matthew L MacDonald, Caitlin M Kirkwood, Ying Ding, Tadhg Schempf, Jackie Jones-Laughner, Julia Kofler, Milos D Ikonomovic, Oscar L Lopez, Megan E Garver, Nicholas F Fitz, Radosveta Koldamova, Nathan A Yate. Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease. Molecular & cellular proteomics : MCP. vol 15. issue 7. 2017-06-20. PMID:27103636. |
apolipoprotein e*4 (apoe*4) genotype is associated with altered levels of glutamate signaling proteins and synaptic coexpression networks in the prefrontal cortex in mild to moderate alzheimer disease. |
2017-06-20 |
2023-08-13 |
human |
| Robert A Sweet, Matthew L MacDonald, Caitlin M Kirkwood, Ying Ding, Tadhg Schempf, Jackie Jones-Laughner, Julia Kofler, Milos D Ikonomovic, Oscar L Lopez, Megan E Garver, Nicholas F Fitz, Radosveta Koldamova, Nathan A Yate. Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease. Molecular & cellular proteomics : MCP. vol 15. issue 7. 2017-06-20. PMID:27103636. |
a subset of ad subjects had altered prefrontal cortex synaptic proteostasis for glutamate receptors and their signaling partners. |
2017-06-20 |
2023-08-13 |
human |