| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Coleman B Calva, Habiba Fayyaz, Jim R Fade. Increased acetylcholine and glutamate efflux in the prefrontal cortex following intranasal orexin-A (hypocretin-1). Journal of neurochemistry. vol 145. issue 3. 2019-05-08. PMID:29250792. |
here, we use immunohistochemistry and in vivo microdialysis to define the effects of acute intranasal oxa administration on: (i) activation of neuronal populations in the cortex, basal forebrain, and brainstem and (ii) acetylcholine (ach) and glutamate efflux in the prefrontal cortex (pfc) of fischer 344/brown norway f1 rats. |
2019-05-08 |
2023-08-13 |
rat |
| Coleman B Calva, Habiba Fayyaz, Jim R Fade. Increased acetylcholine and glutamate efflux in the prefrontal cortex following intranasal orexin-A (hypocretin-1). Journal of neurochemistry. vol 145. issue 3. 2019-05-08. PMID:29250792. |
subsequently, we investigated the effects of acute intranasal oxa on neurotransmitter efflux in the pfc and found that intranasal oxa significantly increased both ach and glutamate efflux in this region. |
2019-05-08 |
2023-08-13 |
rat |
| Coleman B Calva, Habiba Fayyaz, Jim R Fade. Increased acetylcholine and glutamate efflux in the prefrontal cortex following intranasal orexin-A (hypocretin-1). Journal of neurochemistry. vol 145. issue 3. 2019-05-08. PMID:29250792. |
in total, these data indicate that intranasal oxa may enhance cognition through activation of distinct neuronal populations in the cortex and basal forebrain and through increased neurotransmission of ach and glutamate in the pfc. |
2019-05-08 |
2023-08-13 |
rat |
| Lu E Jin, Min Wang, Veronica C Galvin, Taber C Lightbourne, Peter Jeffrey Conn, Amy F T Arnsten, Constantinos D Paspala. mGluR2 versus mGluR3 Metabotropic Glutamate Receptors in Primate Dorsolateral Prefrontal Cortex: Postsynaptic mGluR3 Strengthen Working Memory Networks. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 3. 2019-05-07. PMID:28108498. |
mglur2 versus mglur3 metabotropic glutamate receptors in primate dorsolateral prefrontal cortex: postsynaptic mglur3 strengthen working memory networks. |
2019-05-07 |
2023-08-13 |
Not clear |
| Sarah N Isherwood, Trevor W Robbins, Jeffrey W Dalley, Anton Pekce. Bidirectional variation in glutamate efflux in the medial prefrontal cortex induced by selective positive and negative allosteric mGluR5 modulators. Journal of neurochemistry. vol 145. issue 2. 2019-04-26. PMID:29315577. |
although nmda receptors functionally interact with metabotropic glutamate receptor 5 (mglur5), the consequence of this interaction for glutamate release in the prefrontal cortex (pfc) remains unknown. |
2019-04-26 |
2023-08-13 |
rat |
| Sarah N Isherwood, Trevor W Robbins, Jeffrey W Dalley, Anton Pekce. Bidirectional variation in glutamate efflux in the medial prefrontal cortex induced by selective positive and negative allosteric mGluR5 modulators. Journal of neurochemistry. vol 145. issue 2. 2019-04-26. PMID:29315577. |
we therefore investigated the effects of positive and negative allosteric mglur5 modulation on changes in extracellular glutamate efflux in the medial pfc (mpfc) induced by systemic administration of the non-competitive nmda receptor antagonist dizocilpine (or mk801) in rats. |
2019-04-26 |
2023-08-13 |
rat |
| Ester Francija, Zorica Petrovic, Zeljka Brkic, Milos Mitic, Jelena Radulovic, Miroslav Adzi. Disruption of the NMDA receptor GluN2A subunit abolishes inflammation-induced depression. Behavioural brain research. vol 359. 2019-04-23. PMID:30296532. |
this was accompanied by unaltered levels of il-6 and significant changes in neuroplasticity markers and glutamate receptor subunits composition in pfc and hippocampus. |
2019-04-23 |
2023-08-13 |
mouse |
| Jose Ignacio Pena-Bravo, Rachel Penrod, Carmela M Reichel, Antonieta Lavi. Methamphetamine Self-Administration Elicits Sex-Related Changes in Postsynaptic Glutamate Transmission in the Prefrontal Cortex. eNeuro. vol 6. issue 1. 2019-04-18. PMID:30693312. |
methamphetamine self-administration elicits sex-related changes in postsynaptic glutamate transmission in the prefrontal cortex. |
2019-04-18 |
2023-08-13 |
rat |
| Chi-Hyeon Yoo, Kyu-Ho Song, Song-I Lim, Dong-Cheol Woo, Bo-Young Cho. Metabolic effects of light deprivation in the prefrontal cortex of rats with depression-like behavior: In vivo proton magnetic resonance spectroscopy at 7T. Brain research. vol 1687. 2019-04-09. PMID:29501652. |
the aim of this study was to investigate the effects of light deprivation (ld) in the prefrontal cortex (pfc) of animals with depression-like behavior, targeting the glutamate system, using in vivo proton magnetic resonance spectroscopy ( |
2019-04-09 |
2023-08-13 |
rat |
| José Luis Pérez-López, Rubén Contreras-López, Josué O Ramírez-Jarquín, Fatuel Tecuapetl. Direct Glutamatergic Signaling From Midbrain Dopaminergic Neurons Onto Pyramidal Prefrontal Cortex Neurons. Frontiers in neural circuits. vol 12. 2019-03-25. PMID:30210308. |
recently the ability to release glutamate from a subpopulation of the vta dopaminergic neurons has been shown to control the prefrontal cortex (pfc) excitation through the exclusive innervation of gabaergic fast spiking interneurons. |
2019-03-25 |
2023-08-13 |
Not clear |
| Yusuf Hussain, Sairam Krishnamurth. Piracetam attenuates binge eating disorder related symptoms in rats. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29654794. |
increased levels of plasma corticosterone (cort), glutamate in nucleus accumbens (nac), hypothalamus (hyp) and prefrontal cortex (pfc) indicate stress and excitotoxicity. |
2019-03-15 |
2023-08-13 |
rat |
| Ainhoa Bilbao, Claudia Falfán-Melgoza, Sarah Leixner, Robert Becker, Sathish Kumar Singaravelu, Markus Sack, Alexander Sartorius, Rainer Spanagel, Wolfgang Weber-Fah. Longitudinal Structural and Functional Brain Network Alterations in a Mouse Model of Neuropathic Pain. Neuroscience. vol 387. 2019-03-14. PMID:29694917. |
these changes in connectivity were accompanied by enhanced glutamate levels in the hippocampus, but not in the prefrontal cortex. |
2019-03-14 |
2023-08-13 |
mouse |
| Max E Joffe, Chiaki I Santiago, Branden J Stansley, James Maksymetz, Rocco G Gogliotti, Julie L Engers, Ferdinando Nicoletti, Craig W Lindsley, P Jeffrey Con. Mechanisms underlying prelimbic prefrontal cortex mGlu Neuropharmacology. vol 144. 2019-03-04. PMID:30326237. |
dysregulation of the prefrontal cortex (pfc) glutamate system may underlie these disruptions and restoring pfc glutamate signaling has emerged as a promising avenue for the treatment of stress disorders. |
2019-03-04 |
2023-08-13 |
Not clear |
| Yuko Hara, Johanna L Crimins, Rishi Puri, Athena C J Wang, Sarah E Motley, Frank Yuk, Tiffany M Ramos, William G M Janssen, Peter R Rapp, John H Morriso. Estrogen Alters the Synaptic Distribution of Phospho-GluN2B in the Dorsolateral Prefrontal Cortex While Promoting Working Memory in Aged Rhesus Monkeys. Neuroscience. vol 394. 2019-03-01. PMID:30482274. |
working memory is a cognitive function reliant on persistent firing of dorsolateral prefrontal cortex (dlpfc) neurons that requires the activation of glun2b-containing glutamate nmda receptors. |
2019-03-01 |
2023-08-13 |
monkey |
| Michael T Stefanik, Courtney Sakas, Dennis Lee, Marina E Wol. Ionotropic and metabotropic glutamate receptors regulate protein translation in co-cultured nucleus accumbens and prefrontal cortex neurons. Neuropharmacology. vol 140. 2019-02-20. PMID:30077883. |
ionotropic and metabotropic glutamate receptors regulate protein translation in co-cultured nucleus accumbens and prefrontal cortex neurons. |
2019-02-20 |
2023-08-13 |
Not clear |
| Ruth O'Gorman Tuura, Geoff Warnock, Simon Ametamey, Valerie Treyer, Ralph Noeske, Alfred Buck, Michael Sommeraue. Imaging glutamate redistribution after acute N-acetylcysteine administration: A simultaneous PET/MR study. NeuroImage. vol 184. 2019-02-04. PMID:30296554. |
glutamate (glu), glutamine (gln), and glutamate + glutamine (glx) levels were assessed from mrs data collected from the basal ganglia with press and from the left prefrontal cortex with press and megapress, and mglur5 binding (bp |
2019-02-04 |
2023-08-13 |
human |
| Yusuf S Althobaiti, Fahad S Alshehri, Alqassem Y Hakami, Alaa M Hammad, Youssef Sar. Effects of Clavulanic Acid Treatment on Reinstatement to Methamphetamine, Glial Glutamate Transporters, and mGluR 2/3 Expression in P Rats Exposed to Ethanol. Journal of molecular neuroscience : MN. vol 67. issue 1. 2019-01-31. PMID:30471010. |
in addition, we examined the expression of glt-1, xct, and glast as well as metabotropic glutamate receptor (mglur2/3) in the nucleus accumbens (nac) shell, nac core, and dorsomedial prefrontal cortex (dmpfc). |
2019-01-31 |
2023-08-13 |
rat |
| Caesar M Hernandez, Joseph A McQuail, Miranda R Schwabe, Sara N Burke, Barry Setlow, Jennifer L Bizo. Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory. eNeuro. vol 5. issue 3. 2019-01-25. PMID:29971246. |
glutamate signaling is essential for the persistent neural activity in prefrontal cortex (pfc) that enables working memory. |
2019-01-25 |
2023-08-13 |
rat |
| Jochen Bauer, Anne Werner, Waldemar Kohl, Harald Kugel, Anna Shushakova, Anya Pedersen, Patricia Ohrman. Hyperactivity and impulsivity in adult attention-deficit/hyperactivity disorder is related to glutamatergic dysfunction in the anterior cingulate cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 7. 2019-01-14. PMID:27973969. |
impulsivity, a core symptom in patients with adhd, has been repeatedly associated with glutamatergic neurotransmission, and pharmacological treatment of adhd has been shown to reduce glutamate levels in the prefrontal cortex. |
2019-01-14 |
2023-08-13 |
Not clear |
| Badrah Saeed Ali Alghamd. Possible prophylactic anti-excitotoxic and anti-oxidant effects of virgin coconut oil on aluminium chloride-induced Alzheimer's in rat models. Journal of integrative neuroscience. vol 17. issue 3-4. 2018-12-26. PMID:30010139. |
alzheimer was induced by intraperitoneal injections of aluminium chloride (alcl3) for 45 days (40 ml/kg per day), and our results showed that oral administration of vco (5 ml per day for 30 days) prior to the administration of alcl3 significantly reduced the glutamate level in both the hippocampus and prefrontal cortex compared to an vco non-administrated ad group. |
2018-12-26 |
2023-08-13 |
rat |