| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yukihiko Shirayama, Michio Takahashi, Fumio Osone, Akira Hara, Toshiyuki Okub. Myo-inositol, Glutamate, and Glutamine in the Prefrontal Cortex, Hippocampus, and Amygdala in Major Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 2. issue 2. 2018-12-19. PMID:29560915. |
myo-inositol, glutamate, and glutamine in the prefrontal cortex, hippocampus, and amygdala in major depression. |
2018-12-19 |
2023-08-13 |
Not clear |
| Silvia Rigucci, Lijing Xin, Paul Klauser, Philipp S Baumann, Luis Alameda, Martine Cleusix, Raoul Jenni, Carina Ferrari, Maurizio Pompili, Rolf Gruetter, Kim Q Do, Philippe Conu. Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29075884. |
cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex. |
2018-12-11 |
2023-08-13 |
Not clear |
| Silvia Sacchi, Vito De Novellis, Giovanna Paolone, Tommaso Nuzzo, Monica Iannotta, Carmela Belardo, Marta Squillace, Paolo Bolognesi, Elena Rosini, Zoraide Motta, Martina Frassineti, Alessandro Bertolino, Loredano Pollegioni, Michele Morari, Sabatino Maione, Francesco Errico, Alessandro Usiell. Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity. Scientific reports. vol 7. 2018-11-27. PMID:28393897. |
olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting d-aspartate oxidase activity. |
2018-11-27 |
2023-08-13 |
mouse |
| Benneth Ben-Azu, Adegbuyi Oladele Aderibigbe, Aya-Ebi Okubo Eneni, Abayomi Mayowa Ajayi, Solomon Umukoro, Ezekiel O Iwalew. Morin Attenuates Neurochemical Changes and Increased Oxidative/Nitrergic Stress in Brains of Mice Exposed to Ketamine: Prevention and Reversal of Schizophrenia-Like Symptoms. Neurochemical research. vol 43. issue 9. 2018-11-21. PMID:29956036. |
thereafter, the brain levels of dopamine, glutamate, 5-hydroxytryptamine and acetyl-cholinesterase, as well as biomarkers of oxidative/nitrergic stress were measured in the striatum, prefrontal-cortex (pfc) and hippocampus (hc). |
2018-11-21 |
2023-08-13 |
mouse |
| Chunhua Liu, Shuang Hao, Minghui Zhu, Yingxuan Wang, Tao Zhang, Zhuo Yan. Maternal Separation Induces Different Autophagic Responses in the Hippocampus and Prefrontal Cortex of Adult Rats. Neuroscience. vol 374. 2018-11-20. PMID:29391188. |
compared with the con group, the glutamate level was obviously increased in the hippocampus (hp) and prefrontal cortex (pfc) of rats in the ms group. |
2018-11-20 |
2023-08-13 |
rat |
| Ike C Dela Peña, Guofang Shen, Wei-Xing Sh. Methylphenidate significantly alters the functional coupling between the prefrontal cortex and dopamine neurons in the ventral tegmental area. Neuropharmacology. vol 131. 2018-11-19. PMID:29339293. |
however, the shift in pfc-da cell functional coupling from negative to positive may significantly alter the relative timing between da and glutamate release from da and pfc terminals and thus the synaptic plasticity that depends on da-glutamate interaction. |
2018-11-19 |
2023-08-13 |
Not clear |
| Hanjie Yu, Mengmeng Li, Dongsheng Zhou, Dan Lv, Qi Liao, Zhongze Lou, Mengxin Shen, Zhen Wang, Ming Li, Xiao Xiao, Yanhua Zhang, Chuang Wan. Vesicular glutamate transporter 1 (VGLUT1)-mediated glutamate release and membrane GluA1 activation is involved in the rapid antidepressant-like effects of scopolamine in mice. Neuropharmacology. vol 131. 2018-11-13. PMID:29274366. |
however, little research has addressed the direct mechanisms of scopolamine on ampar activation or vesicular glutamate transporter 1 (vglut1)-mediated glutamate release in the prefrontal cortex (pfc) of mice. |
2018-11-13 |
2023-08-13 |
mouse |
| Hanjie Yu, Mengmeng Li, Dongsheng Zhou, Dan Lv, Qi Liao, Zhongze Lou, Mengxin Shen, Zhen Wang, Ming Li, Xiao Xiao, Yanhua Zhang, Chuang Wan. Vesicular glutamate transporter 1 (VGLUT1)-mediated glutamate release and membrane GluA1 activation is involved in the rapid antidepressant-like effects of scopolamine in mice. Neuropharmacology. vol 131. 2018-11-13. PMID:29274366. |
in addition, knock down of vglut1 by lentiviral-mediated rna interference in the pfc of mice was sufficient to induce depression-like phenotype, to decrease extracellular glutamate accumulation and to cause similar molecular changes with cus in mice. |
2018-11-13 |
2023-08-13 |
mouse |
| K K Szumlinski, C B Shi. Kinase interest you in treating incubated cocaine-craving? A hypothetical model for treatment intervention during protracted withdrawal from cocaine. Genes, brain, and behavior. vol 17. issue 3. 2018-10-01. PMID:29152855. |
rodent models of cocaine addiction indicate that a history of excessive cocaine-taking impacts excitatory glutamate signaling within the prefrontal cortex to drive drug-seeking behavior during protracted withdrawal. |
2018-10-01 |
2023-08-13 |
rat |
| Maria Bove, Kevin Ike, Adriaan Eldering, Bauke Buwalda, Sietse F de Boer, Maria Grazia Morgese, Stefania Schiavone, Vincenzo Cuomo, Luigia Trabace, Martien J H Ka. The Visible Burrow System: A behavioral paradigm to assess sociability and social withdrawal in BTBR and C57BL/6J mice strains. Behavioural brain research. vol 344. 2018-09-04. PMID:29425919. |
neurobiologically, the decreased sociability of btbr was accompanied by reduced gaba and increased glutamate concentrations in brain prefrontal cortex (pfc) and amygdala regions. |
2018-09-04 |
2023-08-13 |
mouse |
| Christina B Shin, Taylor J Templeton, Alvin S Chiu, Jennifer Kim, Ellen S Gable, Philip A Vieira, Tod E Kippin, Karen K Szumlinsk. Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats. Neuropharmacology. vol 128. 2018-07-17. PMID:29061508. |
the incubation of cue-reinforced cocaine-seeking coincides with increased extracellular glutamate within the ventromedial prefrontal cortex (vmpfc). |
2018-07-17 |
2023-08-13 |
rat |
| N Kokras, N Pastromas, D Papasava, C de Bournonville, C A Cornil, C Dall. Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats. Psychoneuroendocrinology. vol 87. 2018-07-13. PMID:29054014. |
the hippocampus and prefrontal cortex (pfc) were analyzed for monoamine (noradrenaline, dopamine and serotonin), as well as amino acid (gaba, glutamate, glycine, taurine, alanine and histidine) levels. |
2018-07-13 |
2023-08-13 |
human |
| Ali Siahposht-Khachaki, Somayeh Ezzatpanah, Yasaman Razavi, Abbas Haghparas. NMDA receptor dependent changes in c-fos and p-CREB signaling following extinction and reinstatement of morphine place preference. Neuroscience letters. vol 662. 2018-06-29. PMID:29054430. |
therefore, in the present study, we tried to evaluate the effect of antagonism of nmda glutamate receptors on the p-creb/creb ratio and c-fos expression in the nac, pfc and hip during these two phases of morphine-cpp in male adult albino wistar rats. |
2018-06-29 |
2023-08-13 |
rat |
| Fengguo Liu, Jingjing Wu, Yu Gong, Peng Wang, Lei Zhu, Lijuan Tong, Xiangfan Chen, Yong Ling, Chao Huan. Harmine produces antidepressant-like effects via restoration of astrocytic functions. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt B. 2018-06-12. PMID:28625859. |
in addition, harmine treatment (20mg/kg) increased the protein expression levels of glutamate transporter 1 (glt-1) and prevented the cus-induced decreases in glial fibrillary acidic protein (gfap) protein expressions in the prefrontal cortex and hippocampus, suggesting that restoration of astrocytic functions may be a potential mechanism underlying the antidepressant-like effects of harmine. |
2018-06-12 |
2023-08-13 |
mouse |
| Ana C Pereira, Xiangling Mao, Caroline S Jiang, Guoxin Kang, Sara Milrad, Bruce S McEwen, Ana C Krieger, Dikoma C Shung. Dorsolateral prefrontal cortex GABA deficit in older adults with sleep-disordered breathing. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 38. 2018-06-08. PMID:28874569. |
levels of gaba and those of the combined resonances of glutamate and glutamine (glx), were measured by 1h mrs in the left dorsolateral prefrontal cortex (l-dlpfc) and bilateral hippocampal regions of 19 older adults (age ± sd: 66.1 ± 1.9 years) with moderate to severe sdb, defined as having an apnea-hypopnea index (ahi) greater than 15 as assessed by polysomnography, and in 14 older adults (age ± sd: 62.3 ± 1.3 years) without sdb (ahi < 5). |
2018-06-08 |
2023-08-13 |
human |
| Robert K McNamara, Ruth H Asch, Jennifer D Schurdak, Diana M Lindquis. Glutamate homeostasis in the adult rat prefrontal cortex is altered by cortical docosahexaenoic acid accrual during adolescence: An in vivo Psychiatry research. Neuroimaging. vol 270. 2018-05-17. PMID:29049903. |
glutamate homeostasis in the adult rat prefrontal cortex is altered by cortical docosahexaenoic acid accrual during adolescence: an in vivo major psychiatric disorders are associated with dysregulated glutamate homeostasis and deficits in the omega-3 fatty acid docosahexaenoic acid (dha). |
2018-05-17 |
2023-08-13 |
rat |
| Aarron Phensy, Christopher Driskill, Karen Lindquist, Lan Guo, Vivek Jeevakumar, Bryan Fowler, Heng Du, Sven Kroene. Antioxidant Treatment in Male Mice Prevents Mitochondrial and Synaptic Changes in an NMDA Receptor Dysfunction Model of Schizophrenia. eNeuro. vol 4. issue 4. 2018-05-03. PMID:28819639. |
glutamate theories of schizophrenia suggest that the disease is associated with a loss of nmda receptors, specifically on gabaergic parvalbumin-expressing interneurons (pvis), leading to changes in the excitation-inhibition balance in the prefrontal cortex (pfc). |
2018-05-03 |
2023-08-13 |
mouse |
| Ding Luo, Rui Ma, Yanan Wu, Xuechun Zhang, Yue Liu, Lin Wang, Wenbin F. Mechanism Underlying Acupuncture-Ameliorated Depressive Behaviors by Enhancing Glial Glutamate Transporter in Chronic Unpredictable Mild Stress (CUMS) Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-26. PMID:28644824. |
the amelioration of depressive behavioral actions was consistent with increasing number of positive cells, protein, and mrna expression of glial glutamate transporter eaat2 in the hippocampus and pfc. |
2018-03-26 |
2023-08-13 |
rat |
| Ding Luo, Rui Ma, Yanan Wu, Xuechun Zhang, Yue Liu, Lin Wang, Wenbin F. Mechanism Underlying Acupuncture-Ameliorated Depressive Behaviors by Enhancing Glial Glutamate Transporter in Chronic Unpredictable Mild Stress (CUMS) Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-26. PMID:28644824. |
enhance glial glutamate transporter eaat2 in the hippocampus and pfc is a mechanism underlying the antidepressant effect of acupuncture. |
2018-03-26 |
2023-08-13 |
rat |
| Ana F Almeida-Santos, Fabricio A Moreira, Francisco S Guimaraes, Daniele C Aguia. 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. Journal of psychopharmacology (Oxford, England). vol 31. issue 6. 2018-03-22. PMID:28440729. |
2-arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. |
2018-03-22 |
2023-08-13 |
rat |