| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neda Valian, Marziyeh Sorayya, Sareh Asadi, Fatemeh Sherafati, Ali Ershad, Sara Savaheli, Abolhassan Ahmadian. Preconditioning by ultra-low dose of tramadol reduces the severity of tramadol-induced seizure: Contribution of glutamate receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33249277. |
the expression of norbin (as a regulator of metabotropic glutamate receptor 5), calponin3 (as a regulator of excitatory synaptic markers), nr1 (nmda receptor subunit 1) and glur1 (ampa receptor subunit 1) was measured in hippocampus, prefrontal cortex (pfc) and amygdala. |
2021-02-24 |
2023-08-13 |
rat |
| Filip S Polli, Malthe B Scharff, Theis H Ipsen, Susana Aznar, Kristi A Kohlmeier, Jesper T Andrease. Prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor associated-genes in the prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 195. 2021-02-08. PMID:32439454. |
prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor associated-genes in the prefrontal cortex. |
2021-02-08 |
2023-08-13 |
mouse |
| Filip S Polli, Malthe B Scharff, Theis H Ipsen, Susana Aznar, Kristi A Kohlmeier, Jesper T Andrease. Prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor associated-genes in the prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 195. 2021-02-08. PMID:32439454. |
in this study, we assessed sex-dependent effects of pne on adhd-related behaviors and on the levels of mrna coding for glutamate receptor subunits within the prefrontal cortex in the outbred nmri mice exposed to nicotine via maternal drinking water during gestation. |
2021-02-08 |
2023-08-13 |
mouse |
| Filip S Polli, Malthe B Scharff, Theis H Ipsen, Susana Aznar, Kristi A Kohlmeier, Jesper T Andrease. Prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor associated-genes in the prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 195. 2021-02-08. PMID:32439454. |
expression of mrna coding for different glutamate receptors subunits within the prefrontal cortex (pfc) was measured using rt-qpcr. |
2021-02-08 |
2023-08-13 |
mouse |
| Filip S Polli, Malthe B Scharff, Theis H Ipsen, Susana Aznar, Kristi A Kohlmeier, Jesper T Andrease. Prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor associated-genes in the prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 195. 2021-02-08. PMID:32439454. |
alterations detected in pfc mrna glutamate receptor proteins could contribute to the abnormal behavioral responses observed, but other signaling pathways or brain regions are likely involved in the behavioral susceptibility of pne individuals. |
2021-02-08 |
2023-08-13 |
mouse |
| Takayoshi Mamiya, Shota Tanase, Shino Takeuchi, Shunsuke Kato, Ai Ito, Masayuki Hiramatsu, Toshitaka Nabeshim. Galantamine improves enhanced impulsivity, impairments of attention and long-term potentiation induced by prenatal nicotine exposure to mice. Biochemical pharmacology. vol 180. 2021-01-11. PMID:32652142. |
decrease of long-term potentiation (ltp) and extracellular glutamate levels were observed in the prefrontal cortex of pne mice. |
2021-01-11 |
2023-08-13 |
mouse |
| Takayoshi Mamiya, Shota Tanase, Shino Takeuchi, Shunsuke Kato, Ai Ito, Masayuki Hiramatsu, Toshitaka Nabeshim. Galantamine improves enhanced impulsivity, impairments of attention and long-term potentiation induced by prenatal nicotine exposure to mice. Biochemical pharmacology. vol 180. 2021-01-11. PMID:32652142. |
further, gal reversed the impairment of ltp induced by pne in the prefrontal cortex of mice, although it failed to attenuate the decrease of extracellular glutamate levels. |
2021-01-11 |
2023-08-13 |
mouse |
| Jakob Kaminski, Tobias Gleich, Yu Fukuda, Teresa Katthagen, Jürgen Gallinat, Andreas Heinz, Florian Schlagenhau. Association of Cortical Glutamate and Working Memory Activation in Patients With Schizophrenia: A Multimodal Proton Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study. Biological psychiatry. vol 87. issue 3. 2021-01-06. PMID:31521336. |
we tested in vivo for group differences in activation of the dorsolateral prefrontal cortex (dlpfc) during wm performance and the association with glutamate concentration in dlpfc depending on medication status. |
2021-01-06 |
2023-08-13 |
Not clear |
| Tina Becher Østerbøg, Doan Minh On, Ignasi Oliveras, Cristóbal Río-Álamos, Ana Sanchez-Gonzalez, Carles Tapias-Espinosa, Adolf Tobeña, Javier González-Maeso, Alberto Fernández-Teruel, Susana Azna. Metabotropic Glutamate Receptor 2 and Dopamine Receptor 2 Gene Expression Predict Sensorimotor Gating Response in the Genetically Heterogeneous NIH-HS Rat Strain. Molecular neurobiology. vol 57. issue 3. 2020-12-04. PMID:31782106. |
expression levels of glutamate metabotropic receptor 2 (grm2), dopamine receptor d2 (drd2), dopamine receptor d1 (drd1), serotonin receptor 1a (htr1a), serotonin receptor 2a (htr2a) and homer scaffolding protein 1 (homer1) were investigated in prefrontal cortex (pfc) and striatum (str). |
2020-12-04 |
2023-08-13 |
rat |
| Nicolaas A Puts, Matthew Ryan, Georg Oeltzschner, Alena Horska, Richard A E Edden, E Mark Mahon. Reduced striatal GABA in unmedicated children with ADHD at 7T. Psychiatry research. Neuroimaging. vol 301. 2020-11-30. PMID:32438277. |
gaba and glutamate were measured in dorsolateral prefrontal cortex (dlpfc), anterior cingulate cortex (acc), premotor cortex (pmc), and striatum, and estimated using lcmodel. |
2020-11-30 |
2023-08-13 |
human |
| Jian-Neng Li, Xi-Long Liu, Long L. Prefrontal GABA and glutamate levels correlate with impulsivity and cognitive function of prescription opioid addicts: A Psychiatry and clinical neurosciences. vol 74. issue 1. 2020-11-23. PMID:31599080. |
this study aimed to quantify γ-aminobutyric acid (gaba) and glutamate (glu) levels in the prefrontal cortex (pfc) of poa patients using proton magnetic resonance spectroscopy ( |
2020-11-23 |
2023-08-13 |
human |
| Fariba Khodagholi, Ali Maleki, Fereshteh Motamedi, Maryam Alsadat Mousavi, Shahrbanoo Rafiei, Mehdi Moslem. Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2. Cellular and molecular neurobiology. 2020-11-17. PMID:33201416. |
anxiety- and depression-like behaviors as well as the levels of oxytocin receptor (oxtr), metabotropic glutamate receptor (mglur) 2, mglur5, and glutathione (gsh) were measured in striatum, hippocampus, prefrontal cortex, and amygdala. |
2020-11-17 |
2023-08-13 |
rat |
| Kristina Becanovic, Maria Vittoria de Donno, Vasco C Sousa, Joakim Tedroff, Per Svenningsso. Effects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and Neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 374. issue 1. 2020-11-12. PMID:32358047. |
irl790 increased pro-brain-derived neurotrophic factor protein levels and phosphorylation at ser1303 of the n-methyl-d-aspartate (nmda) subtype 2b glutamate receptor (nr2b) in prefrontal cortex. |
2020-11-12 |
2023-08-13 |
mouse |
| Danielle M Gerhard, Santosh Pothula, Rong-Jian Liu, Min Wu, Xiao-Yuan Li, Matthew J Girgenti, Seth R Taylor, Catharine H Duman, Eric Delpire, Marina Picciotto, Eric S Wohleb, Ronald S Duma. GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions. The Journal of clinical investigation. vol 130. issue 3. 2020-11-03. PMID:31743111. |
ketamine produces a rapid increase in extracellular glutamate and synaptic formation in the prefrontal cortex, but the initial cellular trigger that initiates this increase and ketamine's behavioral actions has not been identified. |
2020-11-03 |
2023-08-13 |
Not clear |
| Mengxin Shen, Dan Lv, Shuting Li, Yanhua Zhang, Zhen Wang, Chiyu Zhao, Xuejie Chen, Chuang Wan. Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30566581. |
in addition, knock down of vesicular glutamate transporter 1 (vglut1) in the pfc of mice induced depression-like behaviors, whereas treatment with pf-4778574 was sufficient to alleviate it, indicating a presynaptic vglut1 independent effect. |
2020-10-13 |
2023-08-13 |
mouse |
| Shuhei Ueda, Minae Niwa, Hiroyuki Hioki, Jaerin Sohn, Takeshi Kaneko, Akira Sawa, Takeshi Sakura. Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex. Molecular neuropsychiatry. vol 1. issue 2. 2020-10-01. PMID:26457295. |
furthermore, evaluation of the circuitry maturation by measuring extracellular glutamate in pfc revealed that sensitivity to an nmda antagonist became adult-like pattern at p56, suggesting that some of maturation processes continue till p56. |
2020-10-01 |
2023-08-13 |
mouse |
| Tianyi Chen, Yingchan Wang, Jianye Zhang, Zuowei Wang, Jiale Xu, Yao Li, Zhilei Yang, Dengtang Li. Abnormal Concentration of GABA and Glutamate in The Prefrontal Cortex in Schizophrenia.-An in Vivo 1H-MRS Study. Shanghai archives of psychiatry. vol 29. issue 5. 2020-10-01. PMID:29276351. |
abnormal concentration of gaba and glutamate in the prefrontal cortex in schizophrenia.-an in vivo 1h-mrs study. |
2020-10-01 |
2023-08-13 |
Not clear |
| Tianyi Chen, Yingchan Wang, Jianye Zhang, Zuowei Wang, Jiale Xu, Yao Li, Zhilei Yang, Dengtang Li. Abnormal Concentration of GABA and Glutamate in The Prefrontal Cortex in Schizophrenia.-An in Vivo 1H-MRS Study. Shanghai archives of psychiatry. vol 29. issue 5. 2020-10-01. PMID:29276351. |
magnetic resonance spectroscopy (mrs) show glutamate level increases in the ventromedial prefrontal cortex (vmpfc) including the anterior cingulated cortex (acc) in those with schizophrenia. |
2020-10-01 |
2023-08-13 |
Not clear |
| S Hossein Fatemi, Dean F Wong, James R Brašić, Hiroto Kuwabara, Anil Mathur, Timothy D Folsom, Suma Jacob, George M Realmuto, José V Pardo, Susanne Le. Metabotropic glutamate receptor 5 tracer [ Cerebellum & ataxias. vol 5. 2020-10-01. PMID:29449954. |
postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mglur5) in cerebellar vermis and prefrontal cortex of individuals with autism. |
2020-10-01 |
2023-08-13 |
Not clear |
| Eric A Woodcock, Chaitali Anand, Dalal Khatib, Vaibhav A Diwadkar, Jeffrey A Stanle. Working Memory Modulates Glutamate Levels in the Dorsolateral Prefrontal Cortex during Frontiers in psychiatry. vol 9. 2020-10-01. PMID:29559930. |
working memory modulates glutamate levels in the dorsolateral prefrontal cortex during glutamate is involved in excitatory neurotransmission and metabolic processes related to brain function. |
2020-10-01 |
2023-08-13 |
Not clear |