| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ki Chan Kim, Chang Soon Choi, Ji-Woon Kim, Seol-Heui Han, Jae Hoon Cheong, Jong Hoon Ryu, Chan Young Shi. MeCP2 Modulates Sex Differences in the Postsynaptic Development of the Valproate Animal Model of Autism. Molecular neurobiology. vol 53. issue 1. 2016-11-02. PMID:25404090. |
we found male-selective abnormalities in the kinetic profile of the excitatory glutamatergic synaptic protein expressions linked to n-methyl-d-aspartate receptor (nmdar), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampar) and metabotropic glutamate receptor 5 (mglur5) pathways in the prefrontal cortex of the vpa-exposed offspring at postnatal weeks 1, 2, and 4. |
2016-11-02 |
2023-08-13 |
rat |
| Lea M Hulka, Milan Scheidegger, Matthias Vonmoos, Katrin H Preller, Markus R Baumgartner, Marcus Herdener, Erich Seifritz, Anke Henning, Boris B Quedno. Glutamatergic and neurometabolic alterations in chronic cocaine users measured with (1) H-magnetic resonance spectroscopy. Addiction biology. vol 21. issue 1. 2016-11-01. PMID:25600822. |
therefore, we investigated potential differences of glutamate, glutamine and further metabolite levels in the pregenual anterior cingulate cortex (pgacc) and the right dorsolateral prefrontal cortex (rdlpfc) of chronic cocaine users and controls using the prior knowledge fitting 2.0 tool in combination with two-dimensional j-resolved single-voxel (1) h-magnetic resonance spectroscopy at 3t and voxel tissue composition and relaxation correction. |
2016-11-01 |
2023-08-13 |
Not clear |
| Marta González-Sepúlveda, Oscar J Pozo, Josep Marcos, Olga Valverd. Chronic pain causes a persistent anxiety state leading to increased ethanol intake in CD1 mice. Journal of psychopharmacology (Oxford, England). vol 30. issue 2. 2016-10-31. PMID:26681793. |
we analysed behavioural data, neuroinflammation reactions and changes in neurotransmitter (glutamate and serotonin) levels in the mouse prefrontal cortex. |
2016-10-31 |
2023-08-13 |
mouse |
| M N Locklear, A B Cohen, A Jone, M F Kritze. Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 2. 2016-10-11. PMID:25260707. |
sex differences distinguish intracortical glutamate receptor-mediated regulation of extracellular dopamine levels in the prefrontal cortex of adult rats. |
2016-10-11 |
2023-08-13 |
rat |
| Níall Lally, Li An, Dipavo Banerjee, Mark J Niciu, David A Luckenbaugh, Erica M Richards, Jonathan P Roiser, Jun Shen, Carlos A Zarate, Allison C Nugen. Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation. Journal of magnetic resonance imaging : JMRI. vol 43. issue 1. 2016-10-11. PMID:26059603. |
reliability of 7t (1) h-mrs measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized press sequence: a between- and within-sessions investigation. |
2016-10-11 |
2023-08-13 |
human |
| Christina B Shin, Michela M Serchia, John R Shahin, Micaela A Ruppert-Majer, Tod E Kippin, Karen K Szumlinsk. Incubation of cocaine-craving relates to glutamate over-flow within ventromedial prefrontal cortex. Neuropharmacology. vol 102. 2016-10-07. PMID:26522436. |
incubation of cocaine-craving relates to glutamate over-flow within ventromedial prefrontal cortex. |
2016-10-07 |
2023-08-13 |
human |
| Christina B Shin, Michela M Serchia, John R Shahin, Micaela A Ruppert-Majer, Tod E Kippin, Karen K Szumlinsk. Incubation of cocaine-craving relates to glutamate over-flow within ventromedial prefrontal cortex. Neuropharmacology. vol 102. 2016-10-07. PMID:26522436. |
herein, we employed a rat model of cue-elicited cocaine-craving to test the hypothesis that the time-dependent incubation of cue-elicited cocaine-craving is associated with adaptations in dopamine and glutamate neurotransmission within the ventromedial prefrontal cortex (vmpfc). |
2016-10-07 |
2023-08-13 |
human |
| Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Karolina Noworyta-Sokołowska, Paulina Misztak, Joanna Gołębiowska, Katarzyna Młyniec, Beata Ostachowicz, Mirosław Krośniak, Agnieszka Wojtanowska-Krośniak, Krystyna Gołembiowska, Marek Lankosz, Wojciech Piekoszewski, Gabriel Nowa. Alterations of Bio-elements, Oxidative, and Inflammatory Status in the Zinc Deficiency Model in Rats. Neurotoxicity research. vol 29. issue 1. 2016-10-05. PMID:26581375. |
although at 6 weeks zinc level in the pfc did not differ between the zna and znd rats, extracellular zinc concentration after 100 mm kcl stimulation was reduced in the pfc of the znd rats and was accompanied by increased extracellular iron and glutamate levels (as measured by the in vivo microdialysis). |
2016-10-05 |
2023-08-13 |
rat |
| Y Jing, P Liu, B Leitc. Region-specific changes in presynaptic agmatine and glutamate levels in the aged rat brain. Neuroscience. vol 312. 2016-09-29. PMID:26548412. |
this study, for the first time, demonstrates differential effects of aging on agmatine and glutamate in the presynaptic terminals of pfc and te. |
2016-09-29 |
2023-08-13 |
rat |
| Paul E Croarkin, Paul A Nakonezny, Christopher A Wall, Lauren L Murphy, Shirlene M Sampson, Mark A Frye, John D Por. Transcranial magnetic stimulation potentiates glutamatergic neurotransmission in depressed adolescents. Psychiatry research. Neuroimaging. vol 247. 2016-09-16. PMID:26651598. |
high-frequency repetitive transcranial magnetic stimulation applied to the left dorsolateral prefrontal cortex may modulate glutamate neurochemistry in depressed adolescents. |
2016-09-16 |
2023-08-13 |
Not clear |
| Pippa A Thomson, Barbara Duff, Douglas H R Blackwood, Liana Romaniuk, Andrew Watson, Heather C Whalley, Xiang Li, Maria R Dauvermann, T William J Moorhead, Catherine Bois, Niamh M Ryan, Holly Redpath, Lynsey Hall, Stewart W Morris, Edwin J R van Beek, Neil Roberts, David J Porteous, David St Clair, Brandon Whitcher, John Dunlop, Nicholas J Brandon, Zoë A Hughes, Jeremy Hall, Andrew McIntosh, Stephen M Lawri. Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. NPJ schizophrenia. vol 2. 2016-09-07. PMID:27602385. |
translocation carriers also showed significantly increased activation in the caudate nucleus on increasing verbal working memory load, as well as statistically significant reductions in the right dorsolateral prefrontal cortex glutamate concentrations. |
2016-09-07 |
2023-08-13 |
Not clear |
| Dominik Strzelecki, Michał Podgórski, Olga Kałużyńska, Ludomir Stefańczyk, Magdalena Kotlicka-Antczak, Agnieszka Gmitrowicz, Piotr Grzela. Adding Sarcosine to Antipsychotic Treatment in Patients with Stable Schizophrenia Changes the Concentrations of Neuronal and Glial Metabolites in the Left Dorsolateral Prefrontal Cortex. International journal of molecular sciences. vol 16. issue 10. 2016-07-22. PMID:26501260. |
the aim of the study was to evaluate the influence of a six-month course of sarcosine therapy on the concentration of metabolites (naa, n-acetylaspartate; glx, complex of glutamate, glutamine and γ-aminobutyric acid (gaba); mi, myo-inositol; cr, creatine; cho, choline) in the left dorso-lateral prefrontal cortex (dlpfc) in patients with stable schizophrenia. |
2016-07-22 |
2023-08-13 |
Not clear |
| Lewis A Opler, Mark G A Opler, Amy F T Arnste. Ameliorating treatment-refractory depression with intranasal ketamine: potential NMDA receptor actions in the pain circuitry representing mental anguish. CNS spectrums. vol 21. issue 1. 2016-07-19. PMID:25619798. |
this article reviews the antidepressant actions of ketamine, an n-methyl-d-aspartame glutamate receptor (nmdar) antagonist, and offers a potential neural mechanism for intranasal ketamine's ultra-rapid actions based on the key role of nmdar in the nonhuman primate prefrontal cortex (pfc). |
2016-07-19 |
2023-08-13 |
Not clear |
| Alan L Pehrson, Theepica Jeyarajah, Connie Sanche. Regional distribution of serotonergic receptors: a systems neuroscience perspective on the downstream effects of the multimodal-acting antidepressant vortioxetine on excitatory and inhibitory neurotransmission. CNS spectrums. vol 21. issue 2. 2016-07-19. PMID:26250622. |
previous work from this laboratory hypothesized that the multimodal antidepressant vortioxetine enhances cognitive function through a complex mechanism, using serotonergic (5-hydroxytryptamine, 5-ht) receptor actions to modulate gamma-butyric acid (gaba) and glutamate neurotransmission in key brain regions like the prefrontal cortex (pfc) and hippocampus. |
2016-07-19 |
2023-08-13 |
Not clear |
| Alan L Pehrson, Theepica Jeyarajah, Connie Sanche. Regional distribution of serotonergic receptors: a systems neuroscience perspective on the downstream effects of the multimodal-acting antidepressant vortioxetine on excitatory and inhibitory neurotransmission. CNS spectrums. vol 21. issue 2. 2016-07-19. PMID:26250622. |
in this article, we attempt to develop a conceptual framework in which the effects of 5-ht, selective serotonin reuptake inhibitors (ssris), and vortioxetine on gaba and glutamate neurotransmission can be understood in the pfc and striatum-2 regions with roles in cognition and substantially different 5-ht receptor expression patterns. |
2016-07-19 |
2023-08-13 |
Not clear |
| Alan L Pehrson, Theepica Jeyarajah, Connie Sanche. Regional distribution of serotonergic receptors: a systems neuroscience perspective on the downstream effects of the multimodal-acting antidepressant vortioxetine on excitatory and inhibitory neurotransmission. CNS spectrums. vol 21. issue 2. 2016-07-19. PMID:26250622. |
this analysis suggests that 5-ht and ssris will have markedly different effects within the pfc, where they will induce mixed effects on gaba and glutamate neurotransmission, compared to the striatum, where they will enhance gabaergic interneuron activity and drive down the activity of medium spiny neurons. |
2016-07-19 |
2023-08-13 |
Not clear |
| Jing Wei, Zhe Xiong, Janine B Lee, Jia Cheng, Lara J Duffney, Emmanuel Matas, Zhen Ya. Histone Modification of Nedd4 Ubiquitin Ligase Controls the Loss of AMPA Receptors and Cognitive Impairment Induced by Repeated Stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 7. 2016-06-29. PMID:26888924. |
we previously found that repeated stress caused an impairment of prefrontal cortex (pfc)-mediated cognitive functions by increasing the ubiquitination and degradation of ampa-type glutamate receptors via a mechanism depending on the e3 ubiquitin ligase nedd4. |
2016-06-29 |
2023-08-13 |
rat |
| Han-Fang Wu, Hsin-Ju Yen, Chi-Chen Huang, Yi-Chao Lee, Su-Zhen Wu, Tzong-Shyuan Lee, Hui-Ching Li. Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex. Journal of biomedical science. vol 22. 2016-06-20. PMID:26494028. |
whole cell and extracellular recording examined the miniature excitatory postsynaptic currents (mepscs) and field excitatory postsynaptic potentials (fepsps); western blotting determined the protein levels of glutamate receptors and erk phosphorylation in acute medial pfc slices. |
2016-06-20 |
2023-08-13 |
mouse |
| Pauline Luczynski, Luc Moquin, Alain Gratto. Chronic stress alters the dendritic morphology of callosal neurons and the acute glutamate stress response in the rat medial prefrontal cortex. Stress (Amsterdam, Netherlands). vol 18. issue 6. 2016-06-17. PMID:26364921. |
we have previously reported that interhemispheric regulation of medial prefrontal cortex (pfc)-mediated stress responses is subserved by glutamate (glu)- containing callosal neurons. |
2016-06-17 |
2023-08-13 |
rat |
| Crystle J Kelly, Mei Huang, Herbert Meltzer, Marco Martin. Reduced Glutamatergic Currents and Dendritic Branching of Layer 5 Pyramidal Cells Contribute to Medial Prefrontal Cortex Deactivation in a Rat Model of Neuropathic Pain. Frontiers in cellular neuroscience. vol 10. 2016-06-02. PMID:27252623. |
finally, we used in vivo microdialysis to compare the basal concentrations of glutamate and gaba in the pfc of sham and sni rats and found that ambient glutamate is decreased in sni rats. |
2016-06-02 |
2023-08-13 |
rat |