| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gaowei Chen, Shishi Lai, Guo Bao, Jincan Ke, Xiaogao Meng, Shanshan Lu, Xiaocong Wu, Hua Xu, Fengyi Wu, Yu Xu, Fang Xu, Guo-Qiang Bi, Guangdun Peng, Kuikui Zhou, Yingjie Zh. Distinct reward processing by subregions of the nucleus accumbens. Cell reports. vol 42. issue 2. 2023-02-08. PMID:36753418. |
the nucleus accumbens (nac) plays an important role in motivation and reward processing. |
2023-02-08 |
2023-08-14 |
Not clear |
| Valeria Violante-Soria, Silvia L Cruz, Gabriela Rodríguez-Manz. Sexual satiety modifies methamphetamine-induced locomotor and rewarding effects and dopamine-related protein levels in the striatum of male rats. Psychopharmacology. 2023-02-06. PMID:36745226. |
both methamphetamine (meth) and copulation to satiety importantly increase dopamine (da) release in the nucleus accumbens (nac), but with differences in magnitude. |
2023-02-06 |
2023-08-14 |
rat |
| Ethan M Anderson, Evgeny Tsvetkov, Allison Galante, Derek DeVries, Lauren M McCue, Daniel Wood, Sarah Barry, Stefano Berto, Antonieta Lavin, Makoto Taniguchi, Christopher W Cowa. Epigenetic function during heroin self-administration controls future relapse-associated behavior in a cell type-specific manner. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 7. 2023-02-06. PMID:36745812. |
we examined the effects of nucleus accumbens (nac) hdac5 on both heroin- and sucrose-seeking behaviors using operant self-administration paradigms. |
2023-02-06 |
2023-08-14 |
Not clear |
| Seyed Mohammadmisagh Moteshakereh, Mohammad Nikoohemmat, Danial Farmani, Elahe Khosrowabadi, Sakineh Salehi, Abbas Haghparas. The stress-induced antinociceptive responses to the persistent inflammatory pain involve the orexin receptors in the nucleus accumbens. Neuropeptides. vol 98. 2023-02-03. PMID:36736068. |
the contribution of the orexinergic system within the nucleus accumbens (nac) in the modulation of antinociception induced by forced swim stress (fss) remains unclear. |
2023-02-03 |
2023-08-14 |
rat |
| Qiang Lyu, Hecun Zou, Li Luo, Wei Liu, Xiang He, Fei-Fei Shan. The Role of eIF5A1 in LPS-Induced Neuronal Remodeling of the Nucleus Accumbens in the Depression. Journal of integrative neuroscience. vol 22. issue 1. 2023-02-01. PMID:36722231. |
the nucleus accumbens (nac) is a key region in the brain that integrates reward signals. |
2023-02-01 |
2023-08-14 |
Not clear |
| Julianna Cavallaro, Jenna Yeisley, Başak Akdoǧan, Joseph Floeder, Peter D Balsam, Eduardo F Gall. Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711450. |
the neural mechanisms underlying impulsive choice are not well understood, but growing evidence implicates nucleus accumbens (nac) dopamine and its actions on dopamine d2 receptors (d2rs). |
2023-01-30 |
2023-08-14 |
mouse |
| Robert A Phillips, Jennifer J Tuscher, N Dalton Fitzgerald, Ethan Wan, Morgan E Zipperly, Corey G Duke, Lara Ianov, Jeremy J Da. Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711527. |
drugs of abuse increase extracellular concentrations of dopamine in the nucleus accumbens (nac), resulting in transcriptional alterations that drive long-lasting cellular and behavioral adaptations. |
2023-01-30 |
2023-08-14 |
rat |
| Yoshifumi Mizuno, Weidong Cai, Kaustubh Supekar, Kai Makita, Shinichiro Takiguchi, Timothy J Silk, Akemi Tomoda, Vinod Meno. Methylphenidate Enhances Spontaneous Fluctuations in Reward and Cognitive Control Networks in Children With Attention-Deficit/Hyperactivity Disorder. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2023-01-30. PMID:36717325. |
methylphenidate, a first-line treatment for attention-deficit/hyperactivity disorder (adhd), is thought to influence dopaminergic neurotransmission in the nucleus accumbens (nac) and its associated brain circuitry, but this hypothesis has yet to be systematically tested. |
2023-01-30 |
2023-08-14 |
Not clear |
| Min Woo Kim, Jonathan Kipni. Picking a (neuroimmune) fight against fragile regulation of addiction. Cell. 2023-01-24. PMID:36693375. |
regulatory t cell (treg)-derived ifn-γ signaling translates into synaptic weakening in the nucleus accumbens (nac) to impart withdrawal-induced behavioral dysfunction. |
2023-01-24 |
2023-08-14 |
Not clear |
| Yifeng Shi, Mengqi Wang, Linglong Xiao, Luolan Gui, Wen Zheng, Lin Bai, Bo Su, Bin Li, Yangyang Xu, Wei Pan, Jie Zhang, Wei Wan. Potential therapeutic mechanism of deep brain stimulation of the nucleus accumbens in obsessive-compulsive disorder. Frontiers in cellular neuroscience. vol 16. 2023-01-23. PMID:36687525. |
deep brain stimulation (dbs) of the nucleus accumbens (nac) (nac-dbs) is an effective solution to refractory obsessive-compulsive disorder (ocd). |
2023-01-23 |
2023-08-14 |
rat |
| Joseph S Blythe, Alessandra C Mansueto, Sascha B Duken, Henk R Cremer. The generalization of behavioral control over physical threats to social stressors in humans: A pilot fMRI study. Psychiatry research. Neuroimaging. vol 329. 2023-01-21. PMID:36680844. |
the ventromedial prefrontal cortex (vmpfc) may detect the presence of behavioral control over a stressor and communicate this to subcortical regions involved in stress responses, such as the nucleus accumbens (nac). |
2023-01-21 |
2023-08-14 |
Not clear |
| Junhua Yang, Jianan Chen, Yongqing Liu, Kevin Hong Chen, Jay M Baraban, Zhaozhu Qi. Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA. Neuron. 2023-01-21. PMID:36681074. |
repeated cocaine exposure potentiates astrocytic tonic gaba release through volume-regulated anion channels (vracs) and augments tonic inhibition of vta gaba neurons, thus downregulating their activities and disinhibiting nucleus accumbens (nac) projecting da neurons. |
2023-01-21 |
2023-08-14 |
mouse |
| Yongsheng Zhu, Peng Yan, Rui Wang, Jianghua Lai, Hua Tang, Xu Xiao, Rongshan Yu, Xiaorui Bao, Feng Zhu, Kena Wang, Ye Lu, Jie Dang, Chao Zhu, Rui Zhang, Wei Dang, Bao Zhang, Quanze Fu, Qian Zhang, Chongao Kang, Yujie Chen, Xiaoyu Chen, Qing Liang, Kejia Wan. Opioid-induced fragile-like regulatory T cells contribute to withdrawal. Cell. 2023-01-20. PMID:36669483. |
ifn-γ signaling reshaped synaptic morphology in nucleus accumbens (nac) neurons, modulating subsequent withdrawal symptoms. |
2023-01-20 |
2023-08-14 |
mouse |
| Xiao-Bo Wu, Qian Zhu, Ming-Hui Gao, Sheng-Xiang Yan, Pan-Yang Gu, Peng-Fei Zhang, Meng-Lin Xu, Yong-Jing Ga. Excitatory projections from the prefrontal cortex to nucleus accumbens core D1-MSNs and kappa opioid receptor modulate itch-related scratching behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-01-18. PMID:36653189. |
the nucleus accumbens (nac) activity is important in driving sensation, motivation, and emotion. |
2023-01-18 |
2023-08-14 |
mouse |
| J Daniel Obray, Justine D Landin, Dylan T Vaughan, Michael D Scofield, L Judson Chandle. Adolescent alcohol exposure reduces dopamine 1 receptor modulation of prelimbic neurons projecting to the nucleus accumbens and basolateral amygdala. Addiction neuroscience. vol 4. 2023-01-16. PMID:36643604. |
lastly, confocal imaging of proximal and apical dendritic tufts of viral-labelled prl neurons that projected to the nucleus accumbens (nac) revealed aie did not alter the density of dendritic spines. |
2023-01-16 |
2023-08-14 |
rat |
| William B Foster, Katherine F Beach, Paige F Carson, Kagan C Harris, Brandon L Alonso, Leo T Costa, Roy C Simamora, Jaclyn E Corbin, Keegan F Hoag, Sophia I Mercado, Anya G Bernhard, Cary H Leung, Eric J Nestler, Laura E Bee. Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases ∆FosB in D1 and D2 neurons in the nucleus accumbens core in mice. Hormones and behavior. vol 149. 2023-01-16. PMID:36645923. |
these behavioral changes were accompanied by changes in the expression of ∆fosb, a transcription factor correlated with stable long-term plasticity, in the nucleus accumbens (nac). |
2023-01-16 |
2023-08-14 |
mouse |
| Ann M Iturra-Mena, Brian D Kangas, Oanh T Luc, David Potter, Diego A Pizzagall. Electrophysiological signatures of reward learning in the rodent touchscreen-based Probabilistic Reward Task. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-01-16. PMID:36646816. |
we trained 11 rats (5 females and 6 males) on the rodent touchscreen-based prt and subsequently implanted them with deep electrodes in the anterior cingulate cortex (acc) and nucleus accumbens (nac) for local field potentials recordings during the prt. |
2023-01-16 |
2023-08-14 |
rat |
| Allison E Carney, Caitlin Clarke, Wayne E Prat. Administration of Neuropeptide Y into the rat nucleus accumbens shell, but not core, attenuates the motivational impairment from systemic dopamine receptor antagonism by α-flupenthixol. Neuroscience letters. 2023-01-14. PMID:36641044. |
npy and dopamine both modulate appetitive motivation towards food through direct actions in the nucleus accumbens (nac), although how they interact in this region to promote motivation is presently unclear. |
2023-01-14 |
2023-08-14 |
rat |
| Grace E Anderson, Alexandra Sharp, Wayne E Prat. Stimulation of nucleus accumbens 5-HT6 receptors increases both appetitive and consummatory motivation in an effort-based choice task. Neuroreport. vol 34. issue 2. 2023-01-06. PMID:36608167. |
the nucleus accumbens (nac) is a key region involved in motivational processes and has been implicated in the neural mechanisms underlying anhedonia. |
2023-01-06 |
2023-08-14 |
rat |
| Jenya Kolpakova, Vincent van der Vinne, Pablo Gimenez-Gomez, Timmy Le, Gilles E Marti. Binge alcohol drinking alters the differential control of cholinergic interneurons over nucleus accumbens D1 and D2 medium spiny neurons. Frontiers in cellular neuroscience. vol 16. 2023-01-02. PMID:36589290. |
in the nucleus accumbens (nac), a brain region that mediates rewarding properties of substance abuse, acetylcholine regulates glutamatergic, dopaminergic, and gabaergic neurotransmission in naïve mice. |
2023-01-02 |
2023-08-14 |
mouse |