| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jessie Muir, Eshaan S Iyer, Yiu-Chung Tse, Julian Sorensen, Serena Wu, Rand S Eid, Vedrana Cvetkovska, Karen Wassef, Sarah Gostlin, Peter Vitaro, Nick J Spencer, Rosemary C Bago. Sex-biased neural encoding of threat discrimination in nucleus accumbens afferents drives suppression of reward behavior. Nature neuroscience. 2024-09-05. PMID:39237654. |
here, by recording neural activity in two nucleus accumbens (nac) glutamatergic afferents during aversive and neutral cues, we reveal sex-biased encoding of threat cue discrimination. |
2024-09-05 |
2024-09-08 |
mouse |
| Tao Wang, Ruiyang Li, Dongyan Chen, Mei Xie, Zhiqiang Li, Huan Mao, Yuting Ling, Xiaoyun Liang, Guojun Xu, Jianjun Zhan. Modulation of High-Frequency rTMS on Reward Circuitry in Individuals with Nicotine Dependence: A Preliminary fMRI Study. Neural plasticity. vol 2024. 2024-09-05. PMID:39234068. |
functional connectivity (fc) analysis was conducted with reward-related brain regions as seeds, including ventral tegmental area, bilateral nucleus accumbens (nac), bilateral dlpfc, and bilateral amygdala. |
2024-09-05 |
2024-09-08 |
human |
| Christian E Edvardsson, Jesper Vestlund, Mia Ericson, Elisabet Jerlha. The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius. Frontiers in pharmacology. vol 15. 2024-09-02. PMID:39221138. |
investigating ex4-induced neurochemical alterations in the nucleus accumbens (nac) would be valuable for understanding its impact on reward-related behaviors. |
2024-09-02 |
2024-09-04 |
rat |
| David Petersen, Ricardo Raudales, Ariadna Kim Silva, Christoph Kellendonk, Sarah Canett. Adolescent Thalamoprefrontal Inhibition Leads to Changes in Intrinsic Prefrontal Network Connectivity. eNeuro. vol 11. issue 8. 2024-08-29. PMID:39134414. |
here, we used chemogenetic tools to inhibit thalamoprefrontal projections in male/female mice from p20 to p35 and measured synaptic inputs to prefrontal pyramidal neurons by layer (either ii/iii or v/vi) and projection target (mediodorsal thalamus (md), nucleus accumbens (nac), or callosal prefrontal projections) 24 h later using slice physiology. |
2024-08-29 |
2024-09-01 |
mouse |
| Jordan E Elum, Eric R Szelenyi, Barbara Juarez, Alexandria D Murry, Grigory Loginov, Catalina A Zamorano, Pan Gao, Ginny Wu, Scott Ng-Evans, Joshua X Yee, Xiangmin Xu, Sam A Golden, Larry S Zweife. Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation. Cell reports. vol 43. issue 9. 2024-08-29. PMID:39207900. |
we find that the dopamine subpopulation that projects to the nucleus accumbens (nac) core preferentially encodes reward-predictive cues and prediction errors. |
2024-08-29 |
2024-09-04 |
mouse |
| Mohammed S Alasmari, Fawaz Alasmari, Shakir D Alsharari, Abdullah F Alasmari, Nemat Ali, Syed Rizwan Ahamad, Abdullah M Alghamdi, Aban A Kadi, Alaa M Hammad, Yousif S Mohamed Ali, Wayne E Childers, Magid Abou-Gharbia, Youssef Sar. Neuroinflammation and Neurometabolomic Profiling in Fentanyl Overdose Mouse Model Treated with Novel β-Lactam, MC-100093, and Ceftriaxone. Toxics. vol 12. issue 8. 2024-08-28. PMID:39195706. |
in the current study, we characterized the metabolomic profile of the nucleus accumbens (nac) in fentanyl-overdose mouse models, and we evaluated the protective effects of the functional enhancement of glt-1 using β-lactams, ceftriaxone, and mc-100093. |
2024-08-28 |
2024-08-30 |
mouse |
| Marcello Serra, Jacopo Marongiu, Nicola Simola, Giulia Cost. Emission of 50-kHz ultrasonic vocalizations stimulated by antiparkinsonian dopaminomimetic drugs in hemiparkinsonian rats is associated with neuronal activation in subcortical regions that regulate the affective state. Experimental neurology. 2024-08-27. PMID:39191345. |
modified the immunoreactivity for zif-268, a marker of neuronal activation, in the nucleus accumbens (nac), caudate-putamen (cpu) and medial prefrontal cortex (mpfc), which are brain regions that regulate emotional states and drugs' affective properties. |
2024-08-27 |
2024-08-30 |
rat |
| Ying Xu, Yingjie Lin, Ming Yu, Kuikui Zho. The nucleus accumbens in reward and aversion processing: insights and implications. Frontiers in behavioral neuroscience. vol 18. 2024-08-26. PMID:39184934. |
the nucleus accumbens (nac), a central component of the brain's reward circuitry, has been implicated in a wide range of behaviors and emotional states. |
2024-08-26 |
2024-08-28 |
Not clear |
| Sara L Mills-Huffnagle, Charles N Zawatsky, Gjhvona Bryant, Michael Ebert, Corinne M Augusto, Ann Sipe, Nelli Horvath, Jennifer E Nylan. Differences in withdrawal symptoms, microglia activity, and cognitive functioning in rats exposed to continuous low-dose heroin in-utero. Neurotoxicology and teratology. 2024-08-25. PMID:39182528. |
this study evaluated the effects of prenatal heroin exposure and subsequent precipitated withdrawal symptoms on microglial reactivity in the nucleus accumbens (nac), dorsal hippocampus (hc), and ventral tegmental area (vta) in rat neonates, as well as cognitive functioning at three developmental time points using the morris water maze (mwm) task. |
2024-08-25 |
2024-08-28 |
rat |
| Xiajie Feng, Ziyuan Ye, Kailai Xie, Shuqing Zhu, Xin Wu, Zhonghua Sun, Xiaohua Feng, Yingfen Mo, Jingwen Liang, Gang Shu, Songbo Wang, Canjun Zhu, Qingyan Jiang, Lina Wan. Effects of heat stress on the feeding preference of yellow-feathered broilers and its possible mechanism. Journal of thermal biology. vol 124. 2024-08-24. PMID:39180919. |
in the central nervous system, consistent with the change in feeding preference, decreased dopamine in the nucleus accumbens (nac) and increased mrna levels of mao-b in the ventral tegmental area (vta) and nac were found in yellow-feathered broilers (p < 0.05). |
2024-08-24 |
2024-08-28 |
Not clear |
| Elizabeth A Eckenwiler, Anna E Ingebretson, Jeffrey J Stolley, Maxine A Fusaro, Alyssa M Romportl, Jack M Ross, Christopher L Petersen, Eera M Kale, Michael S Clark, Selena S Schattauer, Larry S Zweifel, Julia C Lemo. CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning. Biological psychiatry. 2024-08-24. PMID:39181385. |
the nucleus accumbens (nac) mediates reward learning and motivation. |
2024-08-24 |
2024-08-28 |
Not clear |
| Seulgi Lee, Haemi Choi, Min-Hyeon Park, Bumhee Par. Differential role of negative and positive parenting styles on resting-state brain networks in middle-aged adolescents. Journal of affective disorders. 2024-08-22. PMID:39173921. |
the negative parenting style displayed connections with fc within the reward system, particularly in the left nucleus accumbens (nac), showcasing links to multiple frontal regions. |
2024-08-22 |
2024-08-25 |
Not clear |
| Daniel J Wood, Jessica L Huebschman, Dalia Martinez, Evgeny Tsvetkov, Kirsten Snyder, Raymond Tjhia, Jaswinder Kumar, Brandon W Hughes, Makoto Taniguchi, Laura N Smith, Christopher W Cowan, Rachel D Penro. The activity-regulated cytoskeleton-associated protein (Arc) functions in a cell type- and sex-specific manner in the adult nucleus accumbens to regulate non-contingent cocaine behaviors. Genes, brain, and behavior. vol 23. issue 4. 2024-08-21. PMID:39164860. |
in rodents, the activity-regulated cytoskeleton-associated protein (arc) can regulate glutamatergic synaptic transmission, and cocaine regulates arc expression and subcellular localization in multiple brain regions, including the nucleus accumbens (nac)-a brain region linked to cud-related behavior. |
2024-08-21 |
2024-08-23 |
mouse |
| Yurong Zou, Tong Yu, Liwen Zhu, Qing Xu, Yuhong Li, Juran Chen, Qianyi Luo, Hongjun Pen. Altered dynamic functional connectivity of nucleus accumbens subregions in major depressive disorder: The interactive of childhood trauma and diagnosis. Social cognitive and affective neuroscience. 2024-08-21. PMID:39167467. |
previous research has observed alterations in the reward circuitry centered around the nucleus accumbens (nac) in mdd patients. |
2024-08-21 |
2024-08-24 |
human |
| Paolo S D'Aquil. Licking microstructure in response to novel rewards, reward devaluation and dopamine antagonists: possible role of D1 and D2 medium spiny neurons in the nucleus accumbens. Neuroscience and biobehavioral reviews. 2024-08-19. PMID:39159734. |
evidence on the effect of dopamine d1 and d2-like antagonists and of manipulations of reward value on licking microstructure is reanalysed considering recent findings on the role of nucleus accumbens (nac) medium spiny neurons (msns) in the control of sugar intake. |
2024-08-19 |
2024-08-22 |
Not clear |
| Janay P Franklin, Anze Testen, Piotr A Mieczkowski, Austin Hepperla, Gogce Crynen, Jeremy M Simon, Jonathan D Wood, Eden V Harder, Tania J Bellinger, Emily A Witt, N LaShae Powell, Kathryn J Reissne. Investigating cocaine- and abstinence-induced effects on astrocyte gene expression in the nucleus accumbens. bioRxiv : the preprint server for biology. 2024-08-16. PMID:39149305. |
astrocytes are structurally altered following exposure to drugs of abuse; specifically, astrocytes within the nucleus accumbens (nac) exhibit significantly decreased surface area, volume, and synaptic colocalization after operant self-administration of cocaine and extinction or protracted abstinence (45 days). |
2024-08-16 |
2024-08-18 |
rat |
| Yiqiong Liu, Ying Wang, Zheng-Dong Zhao, Guoguang Xie, Chao Zhang, Renchao Chen, Yi Zhan. A subset of dopamine receptor-expressing neurons in the nucleus accumbens controls feeding and energy homeostasis. Nature metabolism. 2024-08-15. PMID:39147933. |
in addition to hypothalamus neuronal circuits, the nucleus accumbens (nac) also controls appetite and satiety. |
2024-08-15 |
2024-08-18 |
mouse |
| Nao Chuhma, Stephen Raypor. Regional heterogeneity in the membrane properties of mouse striatal neurons. Frontiers in cellular neuroscience. vol 18. 2024-08-15. PMID:39144155. |
all cell types in the nucleus accumbens (nac) shell had higher input impedance and increased excitability. |
2024-08-15 |
2024-08-17 |
mouse |
| Alina-Măriuca Marinescu, Marie A Labouess. The nucleus accumbens shell: a neural hub at the interface of homeostatic and hedonic feeding. Frontiers in neuroscience. vol 18. 2024-08-14. PMID:39139500. |
among the neural structures involved, the nucleus accumbens (nac) has emerged as a pivotal region at the interface of these two circuits. |
2024-08-14 |
2024-08-16 |
Not clear |
| Wenge Jia, Chenchen Li, Hongyun Chen, Xinyu Wang, Yuan Liu, Wanbing Shang, Bian Wang, Wenjing Meng, Yaxin Guo, Lijie Zhu, Dan Wang, Danya Zhou, Bin Zhao, Lai We. ISRIB ameliorates spatial learning and memory impairment induced by adolescent intermittent ethanol exposure in adult male rats. Neurochemistry international. 2024-08-14. PMID:39142353. |
here, we demonstrated that adolescent intermittent ethanol (aie) exposure caused spatial learning and memory impairment, combined with neuronal damage in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hip) in adult rats. |
2024-08-14 |
2024-08-17 |
rat |