| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin Lv, Yuhan Wang, Yingying Zhang, Shuo Ma, Jie Liu, Kuanghao Ye, Yunhao Wu, Valerie Voon, Bomin Su. Auditory entrainment coordinates cortical-BNST-NAc triple time locking to alleviate the depressive disorder. Cell reports. 2024-08-10. PMID:39127041. |
in this study on patients with depression, we used auditory entrainment to evaluate intracranial recordings in the bed nucleus of the stria terminalis (bnst) and nucleus accumbens (nac), along with temporal scalp electroencephalogram (eeg). |
2024-08-10 |
2024-08-13 |
Not clear |
| Chenfeng Zhang, Redas Dulinskas, Christian Ineichen, Alexandra Greter, Hannes Sigrist, Yulong Li, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R Pryc. Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically. Communications biology. vol 7. issue 1. 2024-08-09. PMID:39123076. |
imaging studies in human reward pathology indicate attenuated bold activity in nucleus accumbens (nac) coincident with reward anticipation but not reinforcement; potentially, this is dopamine (da) related. |
2024-08-09 |
2024-08-13 |
mouse |
| Naotaka Izuo, Daiki Ikejima, Kyosuke Uno, Takashi Asano, Shin-Ichi Muramatsu, Atsumi Nitt. Hippocampus-specific knockdown of Shati/Nat8l impairs cognitive function and electrophysiological response in mice. Biochemical and biophysical research communications. vol 736. 2024-08-08. PMID:39116682. |
shati/nat8l was identified as an upregulated molecule in the nucleus accumbens (nac) of mice following repeated methamphetamine administration. |
2024-08-08 |
2024-08-12 |
mouse |
| Brandon W Hughes, Jessica L Huebschman, Evgeny Tsvetkov, Benjamin M Siemsen, Kirsten K Snyder, Rose Marie Akiki, Daniel J Wood, Rachel D Penrod, Michael D Scofield, Stefano Berto, Makoto Taniguchi, Christopher W Cowa. NPAS4 supports cocaine-conditioned cues in rodents by controlling the cell type-specific activation balance in the nucleus accumbens. Nature communications. vol 15. issue 1. 2024-08-08. PMID:39117647. |
drug-associated contexts and cues activate ensembles of nucleus accumbens (nac) neurons, including d1-class medium spiny neurons (msns) that typically promote, and d2-class msns that typically oppose, drug seeking. |
2024-08-08 |
2024-08-12 |
mouse |
| Junseop Lee, Jeongrak Park, Minseok Jeong, Seo-Jin Oh, Jong-Hyuk Yoon, Yong-Seok O. Anatomical topology of extrahippocampal projections from dorsoventral CA pyramidal neurons in mice. Frontiers in neuroanatomy. vol 18. 2024-08-07. PMID:39108929. |
our findings demonstrate that ca1 pns predominantly form unilateral projections to the frontal cortex (pfc), amygdala (amy), nucleus accumbens (nac), and lateral septum (ls), unlike ca2 and ca3 pns making bilateral innervation to the ls only. |
2024-08-07 |
2024-08-09 |
mouse |
| Anna E Ingebretson, Yanaira Alonso-Caraballo, John A Razidlo, Julia C Lemo. Corticotropin releasing factor alters the functional diversity of accumbal cholinergic interneurons. Journal of neurophysiology. vol 132. issue 2. 2024-08-06. PMID:39106208. |
here, we investigated the spontaneous firing patterns of chis in the nucleus accumbens (nac) shell, a region of the ventral striatum. |
2024-08-06 |
2024-08-09 |
Not clear |
| Benjamin C Reiner, Samar N Chehimi, Riley Merkel, Sylvanus Toikumo, Wade H Berrettini, Henry R Kranzler, Sandra Sanchez-Roige, Rachel L Kember, Heath D Schmidt, Richard C Cris. A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens. Scientific reports. vol 14. issue 1. 2024-08-06. PMID:39107568. |
neural processing of rewarding stimuli involves several distinct regions, including the nucleus accumbens (nac). |
2024-08-06 |
2024-08-09 |
mouse |
| María C Gutiérrez, María C Perondi, Gisella L Tortoni, Andrea B Cragnolini, Gabriel R Cuadra, Analía Valdomer. Early protein restriction in rats induces anhedonia in adult offspring: a key role of BDNF-TrkB signaling in the nucleus accumbens shell. Neuropharmacology. 2024-08-04. PMID:39098656. |
to investigate neurobiological substrates linked to early protein undernutrition-facilitated depressive-like behavior, we assessed the levels of brain-derived neurotrophic factor (bdnf) and its receptor trkb in the nucleus accumbens (nac), and evaluated the reversal of anhedonic-like behavior by infusing ana-12. |
2024-08-04 |
2024-08-07 |
rat |
| Javier Cuitavi, Yolanda Campos-Jurado, Jesús D Lorente, Paula Andrés-Herrera, Víctor Ferrís-Vilar, Ana Polache, Lucía Hipólit. Age- and sex-driven alterations in alcohol consumption patterns: Role of brain ethanol metabolism and the opioidergic system in the nucleus accumbens. Pharmacology, biochemistry, and behavior. 2024-08-04. PMID:39098730. |
additionally, to advance in the study of the neurobiological alterations induced by ethanol intake in the mesocorticolimbic system (mcls) that may participate in its reinforcing properties and the maintenance of alcohol drinking behavior, we measured catalase activity-an enzyme involved in alcohol metabolism and related to ethanol reinforcement-in the nucleus accumbens (nac) of these animals. |
2024-08-04 |
2024-08-07 |
rat |
| Xiaoyu Zhong, Jisui Li, Xiaohong X. Adolescent exposure to bisphenol-a antagonizes androgen regulation of social behavior in male mice. Neurotoxicology and teratology. 2024-08-03. PMID:39097242. |
bpa eliminated the reversal effects of tp on gdx-induced decrease in the number of immunoreactive to arginine vasopressin (avp-ir) neurons in the medial amygdala (mea) and the levels of avp receptor 1a (v1ar) in the mea and the nucleus accumbens (nac). |
2024-08-03 |
2024-08-06 |
mouse |
| Ziqian Cheng, Fangyi Zhao, Jingjing Piao, Wei Yang, Ranji Cui, Bingjin L. Rasd2 regulates depression-like behaviors via DRD2 neurons in the prelimbic cortex afferent to nucleus accumbens core circuit. Molecular psychiatry. 2024-08-03. PMID:39097664. |
here, we show that 5-day unpredictable mild stress (5-d ums) exposure reduces rasd2 expression in both the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of mice, while overexpression (but not knock-down) of rasd2 in the nac core (nacc) alleviates 5-d ums-induced depression-like behaviors and activates the drd2-camp-pka-darpp-32 signaling pathway. |
2024-08-03 |
2024-08-06 |
mouse |
| E A Cross, J M Borland, E K Shaughnessy, S D Lee, V Vu, E A Sambor, K L Huhman, H E Alber. Distinct subcircuits within the mesolimbic dopamine system encode the salience and valence of social stimuli. bioRxiv : the preprint server for biology. 2024-08-02. PMID:39091886. |
here, we test the novel hypothesis that projections from the medial ventral tegmental area (vta) to the nucleus accumbens (nac) |
2024-08-02 |
2024-08-05 |
Not clear |
| Irina Balan, Adelina Grusca, Samantha Lucenell Chéry, Baylee R Materia, Todd K O'Buckley, A Leslie Morro. Neurosteroid [3α,5α]-3-Hydroxy-pregnan-20-one Enhances the CX3CL1-CX3CR1 Pathway in the Brain of Alcohol-Preferring Rats with Sex-Specificity. Life (Basel, Switzerland). vol 14. issue 7. 2024-07-27. PMID:39063614. |
this study investigates the impact of allopregnanolone ([3α,5α]3-hydroxypregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-thp); 10 mg/kg, ip) on fractalkine/cx3-c motif chemokine ligand 1 (cx3cl1) levels, associated signaling components, and markers for microglial and astrocytic cells in the nucleus accumbens (nac) of male and female alcohol-preferring (p) rats. |
2024-07-27 |
2024-07-29 |
rat |
| Sydney P Weiner, Kenneth D Car. Behavioral Tests of the Insulin-Cholinergic-Dopamine Link in Nucleus Accumbens and Inhibition by High Fat-High Sugar Diet in Male and Female Rats. Physiology & behavior. 2024-07-27. PMID:39067780. |
the effect of insulin on da release was blocked either by maintaining rats on a high sugar-high fat (hs-hf) diet that induced hyperinsulinemia and nucleus accumbens (nac) insulin receptor insensitivity, or applying the α4β2 antagonist dhβe. |
2024-07-27 |
2024-08-02 |
rat |
| Christina A Nelson, James N Brundage, Benjamin M Williams, Jared K Baldridge, Alyssa L Stockard, Charlton H Bassett, Brandon J Burger, Bridger T Gunter, Andrew J Payne, Jordan T Yorgason, Scott C Steffensen, Kyle B Bill. Voluntary Exercise Ameliorates Chronic Ethanol Withdrawal-Induced Adaptations of Opioid Receptor Expression in the Nucleus Accumbens, Dopamine Release, and Ethanol Consumption. Biomedicines. vol 12. issue 7. 2024-07-27. PMID:39062166. |
chronic ethanol (etoh) exposure has been shown to upregulate and sensitize kappa opioid receptors (kors) in the nucleus accumbens (nac), which is innervated by dopamine (da) neurons in the midbrain ventral tegmental area (vta), which may contribute to aud-related behaviors. |
2024-07-27 |
2024-07-29 |
mouse |
| Stuart J McDougall, Zhi Yi Ong, Rosa Heller, Anna Horton, Kimberly K Thek, Eun A Choi, Gavan P McNally, Andrew J Lawrenc. Viscerosensory signalling to the nucleus accumbens via the solitary tract nucleus. Journal of neurochemistry. 2024-07-20. PMID:39032068. |
a subpopulation of nts neurons project to the nucleus accumbens (nac); however, the function of this nts-nac pathway remains unknown. |
2024-07-20 |
2024-07-24 |
mouse |
| Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Ágota Ádám, András Csilla. Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of neonatal mice. Frontiers in neuroanatomy. vol 18. 2024-07-19. PMID:39026519. |
previous quantitative morphometric studies from our laboratory showed a marked reduction and defasciculation of the mesotelencephalic dopaminergic pathway of vpa treated mice, along with a decrease in tissue dopamine in the nucleus accumbens (nac), but not in the caudatoputamen (cpu). |
2024-07-19 |
2024-07-21 |
mouse |
| Freddyson J Martínez-Rivera, Yun Young Yim, Arthur Godino, Angélica Minier-Toribio, Solange Tofani, Leanne M Holt, Angélica Torres-Berrío, Rita Futamura, Caleb J Browne, Tamara Markovic, Peter J Hamilton, Rachael L Neve, Eric J Nestle. Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026727. |
these neurobiological processes in brain reward regions, such as the nucleus accumbens (nac), are orchestrated in large part by transcriptional regulation. |
2024-07-19 |
2024-07-21 |
mouse |
| Alejandro Dorado, Juan Lorenzo Terrasa, Marian van der Meulen, Pedro Montoya, Ana María González-Roldá. Altered endogenous pain inhibitory function in older adults with chronic pain is associated with disruptions in functional connectivity during resting state. The journal of pain. 2024-07-19. PMID:39029880. |
older adults with chronic pain displayed higher connectivity between primary somatosensory cortex and nucleus accumbens (nac) than pain-free older adults. |
2024-07-19 |
2024-07-22 |
human |
| Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L Jackson, Lynn E Dobrunz, Peter H King, Lori L McMaho. In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat. Brain, behavior, & immunity - health. vol 39. 2024-07-18. PMID:39022628. |
we also assessed whether markers of inflammation or ad-like pathology in the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), basolateral amygdala (bla), or nucleus accumbens (nac), all structures that directly support the aforementioned behaviors, were predictive of behavioral deficits. |
2024-07-18 |
2024-07-20 |
rat |