| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Csaba Vadasz, Beatrix M Gyetva. Genetic association of nucleus accumbens 5-hydroxyindoleacetic acid level and alcohol preference drinking in a quasi-congenic male mice: Potential modulation by Drug and alcohol dependence reports. vol 2. 2023-02-27. PMID:36845900. |
genetic association of nucleus accumbens 5-hydroxyindoleacetic acid level and alcohol preference drinking in a quasi-congenic male mice: potential modulation by to test the hypothesis that predisposition to high alcohol drinking behavior is genetically associated with hypoactive serotonergic function in the nucleus accumbens (nac). |
2023-02-27 |
2023-08-14 |
mouse |
| Eric Y Choi, Daniela Franco, Catherine A Stapf, Madeleine Gordin, Amanda Chow, Kara K Cover, Ramesh Chandra, Mary Kay Lob. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-02-27. PMID:36849419. |
the nucleus accumbens (nac) is a major brain hub mediating reward behavior. |
2023-02-27 |
2023-08-14 |
Not clear |
| Matthew T Birnie, Annabel K Short, Gregory B de Carvalho, Lara Taniguchi, Benjamin G Gunn, Aidan L Pham, Christy A Itoga, Xiangmin Xu, Lulu Y Chen, Stephen V Mahler, Yuncai Chen, Tallie Z Bara. Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice. Nature communications. vol 14. issue 1. 2023-02-25. PMID:36841826. |
we characterize a stress-sensitive projection connecting basolateral amygdala (bla) and nucleus accumbens (nac) that co-expresses gaba and the stress-reactive neuropeptide corticotropin-releasing hormone (crh). |
2023-02-25 |
2023-08-14 |
mouse |
| Sara Guarino, Christopher Hagen, Quynh Nguyen, Mauricio R Papin. Frustrative nonreward and the basal ganglia: Chemogenetic inhibition and excitation of the nucleus accumbens and globus pallidus externus during reward downshift. Neurobiology of learning and memory. 2023-02-23. PMID:36822464. |
these experiments explored the role of the basal ganglia in crd using inhibitory and excitatory dreadds (designer receptors exclusively activated by designer drugs) infused in either the nucleus accumbens (nac) or one of its downstream targets, the globus pallidus externus (gpe). |
2023-02-23 |
2023-08-14 |
Not clear |
| Diana M Cortés-Patiño, Hans Ballesteros-Acosta, Valentyna Martin Neira, David Rikardo Pérez Contreras, Marisol R Lampre. Post-weaning social isolation increases the incentive value of nicotine-related contexts and decreases the accumulation of ΔFosB in nucleus accumbens in adolescent rats. Pharmacology, biochemistry, and behavior. 2023-02-22. PMID:36805863. |
the current study evaluated the effects of differential rearing conditions during adolescence (isolation or group rearing) on (1) conditioned place preference induced by low nicotine doses (0.1 or 0.3 mg/kg) and (2) sensitization to the locomotor effects of nicotine after sub-chronic administration (3) and accumulation of Δfosb in nucleus accumbens (nac). |
2023-02-22 |
2023-08-14 |
rat |
| Matthew R Irwin, Carlos M Curay, Shinbe Choi, Eugene A Kiyatki. Basic metabolic and vascular effects of ketamine and its interaction with fentanyl. Neuropharmacology. 2023-02-21. PMID:36801400. |
by using multi-site thermorecording in freely-moving rats, we showed that intravenous ketamine at a range of human relevant doses (3, 9, 27 mg/kg) dose-dependently increases locomotor activity and brain temperature, as assessed in the nucleus accumbens (nac). |
2023-02-21 |
2023-08-14 |
human |
| Tyson R Baird, Kimberly N Karin, Samuel A Marsh, F Ivy Carroll, J M L Medina-Contreras, S Stevens Negus, Jose M Elti. Rate of onset of dopamine transporter inhibitors assessed with intracranial self-stimulation and in vivo dopamine photometry in rats. Psychopharmacology. 2023-02-21. PMID:36802016. |
additionally, in vivo photometry using the fluorescent da sensor dlight1.1 targeted to the nucleus accumbens (nac) was used to assess the time course of extracellular da levels as a neurochemical correlate of behavioral effects. |
2023-02-21 |
2023-08-14 |
rat |
| Hillary A Wadsworth, Elizabeth Q Anderson, Benjamin M Williams, Joakim W Ronström, Janna K Moen, Anna M Lee, J Michael McIntosh, Jie Wu, Jordan T Yorgason, Scott C Steffense. Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. Molecular neurobiology. 2023-02-21. PMID:36802012. |
the prevailing view is that enhancement of dopamine (da) transmission in the mesolimbic system, consisting of da neurons in the ventral tegmental area (vta) that project to the nucleus accumbens (nac), underlies the reward properties of ethanol (etoh) and nicotine (nic). |
2023-02-21 |
2023-08-14 |
mouse |
| Staci Bilbo, Caroline Smith, Danielle Rendina, Marcy Kingsbury, Karen Malacon, Dang Nguyen, Jessica Tran, Benjamin Devlin, Ravikiran Raju, Madeline Clark, Lauren Burgett, Jason Zhang, Murat Cetinbas, Ruslan Sadreyev, Kevin Chen, Malvika Iye. Microbial modulation prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system. Research square. 2023-02-17. PMID:36798238. |
these behavioral deficits are accompanied by changes in microglial morphology and gene expression as well as decreased dopamine receptor expression and dopaminergic fiber input in the nucleus accumbens (nac). |
2023-02-17 |
2023-08-14 |
mouse |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
cocaine's addictive properties stem from its capacity to increase tonic extracellular dopamine levels in the nucleus accumbens (nac). |
2023-02-16 |
2023-08-14 |
rat |
| Maik Derksen, Birte Zuidinga, Marijke van der Veer, Valerie Rhemrev, Linda Jolink, Liesbeth Reneman, Aart Nederveen, Birte Forstmann, Matthijs Feenstra, Ingo Willuhn, Damiaan Deny. A comparison of how deep brain stimulation in two targets with anti-compulsive efficacy modulates brain activity using fMRI in awake rats. Psychiatry research. Neuroimaging. vol 330. 2023-02-16. PMID:36796237. |
bold-signal intensity was measured in five regions of interest (rois): medial and orbital prefrontal cortex, nucleus accumbens (nac), ic area, and mediodorsal thalamus. |
2023-02-16 |
2023-08-14 |
rat |
| Jonathan R Funke, Eun-Kyung Hwang, Amanda M Wunsch, Raines Baker, Kimberley A Engeln, Conor H Murray, Mike Milovanovic, Aaron J Caccamise, Marina E Wol. Persistent neuroadaptations in the nucleus accumbens core accompany incubation of methamphetamine craving in male and female rats. eNeuro. 2023-02-15. PMID:36792361. |
second, using whole-cell patch-clamp recordings in medium spiny neurons (msns) of the nucleus accumbens (nac) core, we assessed synaptic levels of calcium-permeable ampa receptors (cp-ampars), as their elevation is required for expression of incubation in males. |
2023-02-15 |
2023-08-14 |
rat |
| Scott Russo, Flurin Cathomas, Hsiao-Yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip Swirski, Eric Nestler, Li Shen, Miriam Merad, James Murroug. Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research square. 2023-02-13. PMID:36778505. |
in mice, we show that this increase leads to alterations in extracellular space and neurophysiological changes in the nucleus accumbens (nac), thereby altering social behaviour. |
2023-02-13 |
2023-08-14 |
mouse |
| Alexis N Jameson, Justin K Siemann, James Melchior, Erin S Calipari, Douglas G McMahon, Brad A Gruete. Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics. eNeuro. 2023-02-13. PMID:36781229. |
mesolimbic dopamine input to the nucleus accumbens (nac) contributes to the regulation of affective state and behaviors. |
2023-02-13 |
2023-08-14 |
mouse |
| Shigetaka Kawashima, Fan Lou, Ikue Kusumoto-Yoshida, Liying Hao, Tomoyuki Kuwak. Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice. Scientific reports. vol 13. issue 1. 2023-02-13. PMID:36781929. |
in our previous study using chemogenetic techniques in narcoleptic mice (orexin neuron-ablated mice), we found that the rostral nucleus accumbens (nac) shell is needed for chocolate-induced cataplexy. |
2023-02-13 |
2023-08-14 |
mouse |
| Qing Zhai, Ariful Islam, Bin Chen, Hengsen Zhang, Do Huu Chi, Md Al Mamun, Yutaka Takahashi, Noriko Sato, Hidenori Yamasue, Yoshiki Nakajima, Yu Nagashima, Fumito Sano, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Seto. Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. Cells. vol 12. issue 3. 2023-02-11. PMID:36766735. |
however, the detailed spatial distribution of 2-ag and its changes by crs in stress processing-related anatomical structures such as the anterior cingulate cortex (acc), caudate putamen (cp), nucleus accumbens (nac), and piriform cortex (pir) are still unclear. |
2023-02-11 |
2023-08-14 |
mouse |
| Austin Ganaway, Yoshinori Sunaga, Yasumi Ohta, Jun Ohta, Metin Akay, Yasemin M Aka. Investigating the Modulation of the VTA Neurons in Nicotine-Exposed Pups during Early Maturation Using Optogenetics. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768606. |
this ends in the release of da into the extracellular space of the nucleus accumbens (nac), which is directly modulated by the uptake of da. |
2023-02-11 |
2023-08-14 |
rat |
| Yuki Kurauchi, Yuki Ohta, Keigo Matsuda, Wakana Sanematsu, Hari Prasad Devkota, Takahiro Seki, Hiroshi Katsuk. Matcha Tea Powder's Antidepressant-like Effect through the Activation of the Dopaminergic System in Mice Is Dependent on Social Isolation Stress. Nutrients. vol 15. issue 3. 2023-02-11. PMID:36771286. |
matcha tea powder also increased the number of c-fos-positive cells in the prefrontal cortex (pfc) region and the nucleus accumbens (nac) region in c57bl/6j mice, but not in balb/c mice. |
2023-02-11 |
2023-08-14 |
mouse |
| Chen Yin Ou, Ying Hao Yu, Chi-Wen Wu, Anna Kozłowska, Bai-Chung Shyu, Andrew Chih Wei Huan. Neuronal activity of the medial prefrontal cortex, nucleus accumbens, and basolateral amygdala in conditioned taste aversion and conditioned place preference induced by different doses of morphine administrations in rats. Frontiers in pharmacology. vol 14. 2023-02-10. PMID:36762112. |
to re-examine the paradoxical effect hypothesis of abused drugs, the present study concerned whether different doses of morphine disparately affect neuronal activity and associations among the subareas of the medial prefrontal cortex (mpfc: cingulate cortex 1-cg1, prelimbic cortex-prl, infralimbic cortex-il), the subregions of the nucleus accumbens (nac; both core and shell), and the basolateral amygdala (bla) following conditioned taste aversion (cta) and conditioned place preference (cpp). |
2023-02-10 |
2023-08-14 |
rat |
| Anna L S Beeson, John Meitze. Estrous cycle impacts on dendritic spine plasticity in rat nucleus accumbens core and shell and caudate-putamen. The Journal of comparative neurology. 2023-02-09. PMID:36756791. |
considering the striatal brain regions, the nucleus accumbens (nac) core, nac shell, and caudate-putamen (cpu), the estrous cycle has previously been shown to impact relevant behaviors and disorders, neuromodulator action, and medium spiny neuron (msn) electrophysiology. |
2023-02-09 |
2023-08-14 |
human |