| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Botao Xiong, Bin Li, Rong Wen, Yuan Gao, Feilong Gong, Denghui Li, Yangyang Xu, Hao Deng, Linglong Xiao, Senlin Yin, Wei Zhang, Andres M Lozano, Wei Wan. Use of differential stimulation of the nucleus accumbens and anterior limb of the internal capsule to improve outcomes of obsessive-compulsive disorder. Journal of neurosurgery. 2023-05-27. PMID:37243560. |
therefore, a novel designed electrode and implantable pulse generator (ipg) that could achieve differential stimulation parameters for different contacts was implanted into the nucleus accumbens (nac) and anterior limb of the internal capsule (alic) of a cohort of patients with ocd. |
2023-05-27 |
2023-08-14 |
Not clear |
| Ruijie Jin, Shanbin Sun, Yang Hu, Hongfei Zhang, Xiangrong Su. Neuropeptides Modulate Feeding via the Dopamine Reward Pathway. Neurochemical research. 2023-05-26. PMID:37233918. |
the reward system comprises the ventral tegmental area (vta), nucleus accumbens (nac), hypothalamus, and limbic system. |
2023-05-26 |
2023-08-14 |
Not clear |
| Suthinee Attachaipanich, Takaaki Ozawa, Tom Macpherson, Takatoshi Hikid. Dual roles for nucleus accumbens core dopamine D1-expressing neurons projecting to the substantia nigra pars reticulata in limbic and motor control in male mice. eNeuro. 2023-05-26. PMID:37236787. |
the nucleus accumbens (nac) is a critical component of a limbic basal ganglia circuit that is thought to play an important role in decision-making and the processing of rewarding stimuli. |
2023-05-26 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
here, we use the fluorescent sensor grabda to record, with millisecond resolution, every single cocaine-evoked dopamine transient in the nucleus accumbens (nac) of freely moving mice during self-administration. |
2023-05-24 |
2023-08-14 |
mouse |
| Melina Matthiesen, Abdessattar Khlaifia, Carl Frank David Steininger, Maryam Dadabhoy, Unza Mumtaz, Maithe Arruda-Carvalh. Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder. Molecular brain. vol 16. issue 1. 2023-05-24. PMID:37226266. |
the nucleus accumbens (nac), a brain region extensively implicated in social behavior, undergoes synaptic, cellular and molecular alterations in early life, and is particularly affected in asd mouse models. |
2023-05-24 |
2023-08-14 |
mouse |
| Angélica Torres-Berrío, Molly Estill, Aarthi Ramakrishnan, Hope Kronman, Vishwendra Patel, Angélica Minier-Toribio, Orna Issler, Caleb J Browne, Eric M Parise, Yentl van der Zee, Deena Walker, Freddyson J Martínez-Rivera, Casey K Lardner, Romain Durand-de Cuttoli, Scott J Russo, Li Shen, Simone Sidoli, Eric J Nestle. Monomethylation of Lysine 27 at Histone 3 Confers Lifelong Susceptibility to Stress. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214877. |
specifically, mice exposed to early life stress (els) or to chronic social defeat stress (csds) in adulthood displayed increased enrichment of h3k27me1, and transient decreases in h3k27me2, in the nucleus accumbens (nac), a key brain-reward region. |
2023-05-23 |
2023-08-14 |
mouse |
| Julianna Cavallaro, Jenna Yeisley, Başak Akdoǧan, Ronald E Salazar, Joseph R Floeder, Peter D Balsam, Eduardo F Gall. Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-05-23. PMID:37221325. |
the neural mechanisms underlying impulsive choice are not well understood, but growing evidence implicates nucleus accumbens (nac) dopamine and its actions on dopamine d2 receptors (d2rs). |
2023-05-23 |
2023-08-14 |
mouse |
| Jie Zhang, Yiting Peng, Chengxi Liu, Yu Zhang, Xiaoli Liang, Chengdong Yuan, Wenyan Shi, Yi Zhan. Dopamine D1-receptor-expressing pathway from the nucleus accumbens to ventral pallidum-mediated sevoflurane anesthesia in mice. CNS neuroscience & therapeutics. 2023-05-20. PMID:37208941. |
studies in mice have shown that microinjection of dopamine receptor 1 (d1r) agonists into the nucleus accumbens (nac) promotes recovery from isoflurane anesthesia, while microinjection of d1r antagonists has the opposite effect. |
2023-05-20 |
2023-08-14 |
mouse |
| Julia M Kirkland, Erin L Edgar, Ishan Patel, Ashley M Kope. Impaired microglia-mediated synaptic pruning in the nucleus accumbens during adolescence results in persistent dysregulation of familiar, but not novel social interactions in sex-specific ways. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205324. |
the nucleus accumbens (nac) is an intermediate reward relay center that develops during adolescence and mediates both social behaviors and dopaminergic signaling. |
2023-05-19 |
2023-08-14 |
human |
| J M Kirkland, Ishan Patel, Monali S Ardeshna, Ashley M Kope. Microglial synaptic pruning in the nucleus accumbens during adolescence sex-specifically influences splenic immune outcomes. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205376. |
we published that microglia-mediated synaptic pruning occurs in the nucleus accumbens (nac) reward region during adolescence to mediate social development in male and female rats. |
2023-05-19 |
2023-08-14 |
rat |
| J M Kirkland, Ishan Patel, Ashley M Kope. Microglia-mediated synaptic pruning in the nucleus accumbens during adolescence: A preliminary study of the proteomic consequences and putative female-specific pruning target. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205455. |
we published that microglia-c3-mediated synaptic pruning also occurs in the nucleus accumbens (nac) reward region during adolescence to mediate social development in male and female rats. |
2023-05-19 |
2023-08-14 |
rat |
| Kevin M Manz, José C Zepeda, Zack Zurawski, Heidi E Hamm, Brad A Gruete. SNAP25 differentially contributes to G Frontiers in cellular neuroscience. vol 17. 2023-05-19. PMID:37206665. |
snap25 differentially contributes to g the nucleus accumbens (nac) guides reward-related motivated behavior implicated in pathological behavioral states, including addiction and depression. |
2023-05-19 |
2023-08-14 |
Not clear |
| Sam Z Bacharach, David A Martin, Cassie A Stapf, Fangmiao Sun, Yulong Li, Joseph F Cheer, Donna J Cal. Decreased ventral tegmental area CB1R signaling reduces sign-tracking and shifts cue-outcome dynamics in rat nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-19. PMID:37208179. |
cue-evoked dopamine in the nucleus accumbens (nac) is a neurobiological signature of sign-tracking behaviors. |
2023-05-19 |
2023-08-14 |
rat |
| Wei-Zhu Liu, Chun-Yan Wang, Yu Wang, Mei-Ting Cai, Wei-Xiang Zhong, Tian Liu, Zhi-Hao Wang, Han-Qing Pan, Wen-Hua Zhang, Bing-Xing Pa. Circuit- and laminar-specific regulation of medial prefrontal neurons by chronic stress. Cell & bioscience. vol 13. issue 1. 2023-05-19. PMID:37208769. |
the medial prefrontal cortex (mpfc) is a hub for controlling stress responses through communicating with multiple limbic structures, including the basolateral amygdala (bla) and nucleus accumbens (nac). |
2023-05-19 |
2023-08-14 |
Not clear |
| Caroline J Smith, Danielle N Rendina, Marcy A Kingsbury, Karen E Malacon, Dang M Nguyen, Jessica J Tran, Benjamin A Devlin, Ravikiran M Raju, Madeline J Clark, Lauren Burgett, Jason H Zhang, Murat Cetinbas, Ruslan I Sadreyev, Kevin Chen, Malvika S Iyer, Staci D Bilb. Microbial modulation via cross-fostering prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system. Molecular psychiatry. 2023-05-17. PMID:37198262. |
these behavioral deficits are accompanied by changes in microglial morphology and gene expression as well as decreased dopamine receptor expression and dopaminergic fiber input in the nucleus accumbens (nac). |
2023-05-17 |
2023-08-14 |
mouse |
| Jianjun Zhang, Zhuo Liu, Xiaodong Liu, Xiaoqian Wang, Longchuan Y. Intravenous Injection of GluR2-3Y Inhibits Repeated Morphine-Primed Reinstatement of Drug Seeking in Rats. Brain sciences. vol 13. issue 4. 2023-05-16. PMID:37190555. |
the long-term depression (ltd) in the nucleus accumbens (nac) shell was also assessed. |
2023-05-16 |
2023-08-14 |
rat |
| C A Favoretto, N B Bertagna, T Righi, B T Rodolpho, A Anjos-Santos, F B R Silva, P C Bianchi, F C Cru. Impacts of maternal separation stress on ethanol-related responses, anxiety- and depressive-like behaviors in adolescent mice. Neuroscience letters. 2023-05-14. PMID:37182574. |
our results demonstrated that ms increased ethanol intake only in an acute manner and did not impact ethanol-induced fos expression in the dorsal striatum and nucleus accumbens (nac) core and shell subregions. |
2023-05-14 |
2023-08-14 |
mouse |
| Sukanya G Gakare, Rajesh R Ugal. Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference. Behavioural pharmacology. vol 34. issue 4. 2023-05-12. PMID:37171461. |
in immunohistochemistry, we found that pdc administration significantly decreased, whereas lamotrigine treatment significantly increased tyrosine hydroxylase immunoreactivity (th-ir) in vta and nucleus accumbens (nac). |
2023-05-12 |
2023-08-14 |
Not clear |
| Cheng-Bo He, Yuan Jin, Yan Li, Qian Zhang, Bai Yang, Mang Xu, Juan Yang, Xi-Nan Yi, Yu-Lin Dong, Jian Wang, Yun-Qing L. Collateral projections from the ventral tegmental area/substantia nigra pars compacta to the nucleus accumbens and insular cortex in the rat. Anatomical science international. 2023-05-10. PMID:37160827. |
previous studies demonstrated that the vta/snc to nucleus accumbens (nac) pathway is critical in reward and motivation. |
2023-05-10 |
2023-08-14 |
rat |
| F Javier Rubio, Daniel E Olivares, Christopher Dunn, Shiliang Zhang, Elias M Hilaire, Akeem Henry, Carlos Mejias-Aponte, Carlos J Nogueras-Ortiz, Pooja V Selvam, Fabio C Cruz, Rajtarun Madangopal, Marisela Morales, Bruce T Hop. Flow cytometry of synaptoneurosomes (FCS) reveals increased ribosomal S6 and calcineurin proteins in activated medial prefrontal cortex to nucleus accumbens synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-09. PMID:37160369. |
after injecting yfp-expressing aav into medial prefrontal cortex (mpfc) to label terminals in nucleus accumbens (nac) of rats, we injected 20 mg/kg of cocaine in a novel context (cocaine+novelty) to activate synapses, and prepared nac synaptoneurosomes 0-60 min following injections. |
2023-05-09 |
2023-08-14 |
rat |