| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiyoung S Kim, Kevin C Williams, Rebecca A Kirkland, Ruth Schade, Kimberly G Freeman, Carolina R Cawthon, Allison W Rautmann, Jessica M Smith, Gaylen L Edwards, Travis C Glenn, Philip V Holmes, Guillaume de Lartigue, Claire B de La Serr. The gut-brain axis mediates bacterial driven modulation of reward signaling. Molecular metabolism. 2023-06-28. PMID:37380023. |
convhf rats displayed lower feeding-induced extracellular dopac levels (a metabolite of dopamine) in the nucleus accumbens (nac) as well as reduced motivation for hf foods compared to convlf rats. |
2023-06-28 |
2023-08-14 |
rat |
| Laura Santana Cordón, Domingo Afonso-Oramas, Alejandro Lemus Mesa, Miriam González-Gómez, Pedro Barroso-Chine. Morphological study of neuropeptide Y expression in human and mouse anterior insular cortex: overexpression in the insular cortex and nucleus accumbens in obese mice on a long-term obesogenic diet. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2023-06-24. PMID:37355144. |
the anterior lobe of the insular cortex (ains) is a cortical region that has reciprocal connections with limbic centers such as the anterior cingulate cortex, prefrontal cortex, amygdala and nucleus accumbens (nac). |
2023-06-24 |
2023-08-14 |
mouse |
| Amanda M Catalfio, Tracy L Fetterly, Allison M Nieto, Terry E Robinson, Carrie R Ferrari. Cocaine-induced sensitization and glutamate plasticity in the nucleus accumbens core: effects of sex. Biology of sex differences. vol 14. issue 1. 2023-06-24. PMID:37355656. |
the development and persistence of addiction is mediated in part by drug-induced alterations in nucleus accumbens (nac) function. |
2023-06-24 |
2023-08-14 |
Not clear |
| Yafang Zhang, Jennifer Ben Nathan, Amanda Moreno, Riley Merkel, Michelle W Kahng, Matthew R Hayes, Benjamin C Reiner, Richard C Crist, Heath D Schmid. Calcitonin receptor signaling in nucleus accumbens D1R- and D2R-expressing medium spiny neurons bidirectionally alters opioid taking in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-24. PMID:37355732. |
here, we used single nuclei rna sequencing (snrna-seq), fluorescent in situ hybridization (fish), and immunohistochemistry (ihc) to characterize cell type-specific patterns of ctr expression in the nucleus accumbens (nac), a brain region that plays a critical role in voluntary drug taking. |
2023-06-24 |
2023-08-14 |
rat |
| Jing Yan, Bei-Ning Hang, Lin-Hui Ma, Jia-Tao Lin, Yue Zhou, Xin-Hao Jiao, Ying-Xuan Yuan, Ke-Jie Shao, Le-Meng Zhang, Qi Xue, Zi-Yi Li, Hong-Xing Zhang, Jun-Li Cao, Shuai Li, Hui Zheng, Yu-Qing W. GABAergic Neurons in the Nucleus Accumbens are Involved in the General Anesthesia Effect of Propofol. Molecular neurobiology. 2023-06-22. PMID:37349621. |
in essence, the nucleus accumbens (nac) is crucial for regulating wakefulness and may be directly engaged in the principle of general anesthesia. |
2023-06-22 |
2023-08-14 |
Not clear |
| Federica Lucantonio, Shuwen Li, Jaden Lu, Jacob Roeglin, Leonardo Bontempi, Brenda C Shields, Carlos A Zarate, Michael R Tadross, Marco Pignatell. Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333325. |
here, we show that the nucleus accumbens (nac), a major hub of the reward circuitry, is essential for ketamine's effect in rescuing anhedonia in mice subjected to chronic stress, a critical risk factor in the genesis of depression in humans. |
2023-06-19 |
2023-08-14 |
mouse |
| Liping Ma, He Liu, Ziyi Xu, Mengli Yang, Yinghua Zhan. Application of the WholeBrain Calculation Interactive Framework to Map Whole-Brain Neural Connectivity Networks. Journal of chemical neuroanatomy. 2023-06-18. PMID:37331669. |
wild-type c57bl/6j mice (n = 10) aged 8-10 weeks were injected with the cholera toxin subunit b (ctb) tracer in the anterior (nacca) and posterior (naccp) parts of the nucleus accumbens (nac) core and in the medial (nacsm) and lateral (nacsl) parts of the nac shell. |
2023-06-18 |
2023-08-14 |
mouse |
| Ali R Rezai, James J Mahoney, Manish Ranjan, Marc W Haut, Wanhong Zheng, Laura R Lander, James H Berry, Daniel L Farmer, Jennifer L Marton, Padma Tirumalai, Ashley Mears, Daisy G Y Thompson-Lake, Victor S Finomore, Pierre-François D'Haese, Will M Aklin, David T George, John D Corrigan, Sally L Hodde. Safety and feasibility clinical trial of nucleus accumbens deep brain stimulation for treatment-refractory opioid use disorder. Journal of neurosurgery. 2023-06-17. PMID:37329519. |
the objective of this study was to evaluate the safety and feasibility of deep brain stimulation (dbs) targeting the nucleus accumbens (nac)/ventral capsule (vc) and potential impact on outcomes in individuals with treatment-refractory oud. |
2023-06-17 |
2023-08-14 |
Not clear |
| David Levcik, Adam H Sugi, Marcelo Aguilar-Rivera, José A Pochapski, Gabriel Baltazar, Laura N Pulido, Cyrus Villas Boas, Romulo Fuentes-Flores, Saleem M Nicola, Claudio Da Cunh. Nucleus accumbens shell neurons encode the kinematics of reward approach locomotion. Neuroscience. 2023-06-17. PMID:37330195. |
the nucleus accumbens (nac) is considered an interface between motivation and action, with nac neurons playing an important role in promoting reward approach. |
2023-06-17 |
2023-08-14 |
rat |
| Kyle D Ketchesin, Darius D Becker-Krail, Xiangning Xue, Rashaun S Wilson, TuKiet T Lam, Kenneth R Williams, Angus C Nairn, George C Tseng, Ryan W Loga. Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. Journal of proteome research. 2023-06-13. PMID:37311105. |
repeated use of substances such as psychostimulants and opioids may lead to significant alterations in molecular rhythms in the nucleus accumbens (nac), a brain region central to reward and motivation. |
2023-06-13 |
2023-08-14 |
mouse |
| Ihsan Serhatlioglu, Mete Ozcan, Emine Kacar, Tuncay Kuloglu, Nalan Kaya Tektemur, Funda Gulcu Bulmus, Ozgur Bulmus, Fatih Tan, Zubeyde Ercan, Nazife Ulker Ertugrul, Ahmet Yardımcı, Gokhan Zorlu, Haluk Kelestımu. TRPM2 may be involved in high fructose corn syrup-induced anxiety-like behavior in adult male rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 3. 2023-06-11. PMID:37300693. |
trpm2 immunoreactivity significantly increased in the hippocampus, prefrontal cortex (pfc), nucleus accumbens (nac), and amygdala regions by hfcs and cis treatments. |
2023-06-11 |
2023-08-14 |
rat |
| Tracy L Fetterly, Amanda M Catalfio, Carrie R Ferrari. Effects of junk-food on food-motivated behavior and NAc glutamate plasticity; insights into the mechanism of NAc calcium-permeable AMPA receptor recruitment. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292760. |
in rats, eating obesogenic diets increase calcium-permeable ampa receptor (cp-ampar) transmission in the nucleus accumbens (nac) core, and enhances food-motivated behavior. |
2023-06-09 |
2023-08-14 |
rat |
| Madalyn Hafenbreidel, Sherri B Briggs, Meghana Arza, Shalakha Bonthu, Cadence Fisher, Annika Tiller, Alice B Hall, Shayna Reed, Natasha Mayorga, Li Lin, Susan Khan, Michael D Cameron, Gavin Rumbaugh, Courtney A Mille. Basolateral Amygdala Corticotrophin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292925. |
dorsal hippocampus [dphc], nucleus accumbens [nac]), nor does it interfere with associations for other aversive or appetitive stimuli, including cocaine (coc). |
2023-06-09 |
2023-08-14 |
Not clear |
| Ali Mohebi, Val L Collins, Joshua D Berk. Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation. eLife. vol 12. 2023-06-05. PMID:37272423. |
motivation to work for potential rewards is critically dependent on dopamine (da) in the nucleus accumbens (nac). |
2023-06-05 |
2023-08-14 |
rat |
| Zhaosong Chu, Lijin Yuan, Mengxin He, Yuqi Cheng, Yi Lu, Xiufeng Xu, Zonglin She. Atrophy of bilateral nucleus accumbens in melancholic depression. Neuroreport. vol 34. issue 10. 2023-06-04. PMID:37270840. |
evidence from previous literature suggests that the nucleus accumbens (nac), hippocampus, and amygdala play critical roles in the reward circuit. |
2023-06-04 |
2023-08-14 |
human |
| Alyse N Maksimoski, Sharon A Stevenson, Brandon J Polzin, Changjiu Zhao, Elsa M Luebke, Lauren V Riter. The motivation to flock correlates with vocal-social behaviors and dopamine-related gene expression in male European starlings. Hormones and behavior. vol 153. 2023-06-04. PMID:37271085. |
the nucleus accumbens (nac), medial preoptic area (pom), and ventral tegmental area (vta) are implicated in vocal-social behaviors in flocks, including singing. |
2023-06-04 |
2023-08-14 |
Not clear |
| Pengbo Jing, Qiang Sha. Exogenous oxytocin microinjection into the nucleus accumbens shell attenuates social dominance in group-housed male mice. Physiology & behavior. 2023-06-03. PMID:37270150. |
the nucleus accumbens (nac), a part of the brain's limbic system, is involved in a variety of brain functions, including reward motivation and social hierarchy. |
2023-06-03 |
2023-08-14 |
mouse |
| Hsiao-Ying Kuo, Ya-Hui Yang, Shih-Yun Chen, Tzu-Hsin Kuo, Wan-Ting Lin, Fu-Chin Li. Differential development of dendritic spines in striatal projection neurons of direct and indirect pathways in the caudoputamen and nucleus accumbens. eNeuro. 2023-05-30. PMID:37253589. |
here, we delineate the developmental trajectories of dendritic spines of dspns and ispns in the caudoputamen and nucleus accumbens (nac). |
2023-05-30 |
2023-08-14 |
mouse |
| Daniel R Garton, Giorgio Turconi, Vilma Iivanainen, Jaan-Olle Andresso. Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction. Biomolecules. vol 13. issue 5. 2023-05-27. PMID:37238631. |
similarly, after establishing cocaine-induced conditioned place preference, we studied the effect of conditionally reducing gdnf in the ventral striatum nucleus accumbens (nac), the target of mesolimbic dopaminergic innervation. |
2023-05-27 |
2023-08-14 |
Not clear |
| Vidhya Kumaresan, Yolpanhchana Lim, Poorva Juneja, Allison E Tipton, Giordano de Guglielmo, Lieselot L G Carrette, Marsida Kallupi, Lisa Maturin, Ying Liu, Olivier George, Huiping Zhan. Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37239038. |
small rna sequencing (srna-seq) was used to profile mirna transcriptomic changes in the cortico-accumbal pathway [infralimbic- and prelimbic-prefrontal cortex (il and pl) and nucleus accumbens (nac)] of rats with extended access to cocaine self-administration followed by an 18-h withdrawal or a 4-week abstinence. |
2023-05-27 |
2023-08-14 |
rat |