| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasmin Olsson, Helga Lidö, Karin Ademar, Davide Cadeddu, Mia Ericson, Bo Söderpal. The GlyT1-inhibitor Org 24598 facilitates the alcohol deprivation abolishing and dopamine elevating effects of bupropion + varenicline in rats. Journal of neural transmission (Vienna, Austria : 1996). 2023-09-29. PMID:37773223. |
also, direct and indirect glycine receptor (glyr) agonists raise basal da, attenuate alcohol-induced da release in the nucleus accumbens (nac) and reduce alcohol consumption in rats. |
2023-09-29 |
2023-10-07 |
rat |
| Kristyn N Borrelli, Kelly K Wingfield, Emily J Yao, Catalina A Zamorano, Katherine D Sena, Jacob A Beierle, Michelle A Roos, Huiping Zhang, Elisha M Wachman, Camron D Bryan. Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice. Neuropharmacology. 2023-09-29. PMID:37774943. |
we used a third trimester-approximate model in which neonatal outbred pups (carworth farms white; cfw) were administered once-daily morphine (15 mg/kg, s.c.) from postnatal day (p) day 1 through p14 and were then assessed for behavioral and transcriptomic adaptations within the nucleus accumbens (nac) on p15. |
2023-09-29 |
2023-10-07 |
mouse |
| Gavin C Jones, Christina A Small, Dallin Z Otteson, Caylor W Hafen, Jacob T Breinholt, Paul D Flora, Matthew D Burris, David W Sant, Tysum R Ruchti, Jordan T Yorgason, Scott C Steffensen, Kyle B Bill. Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762450. |
peripheral mechanoreceptor-based treatments such as acupuncture and chiropractic manipulation have shown success in modulating the mesolimbic dopamine (da) system originating in the ventral tegmental area (vta) of the midbrain and projecting to the nucleus accumbens (nac) of the striatum. |
2023-09-28 |
2023-10-07 |
rat |
| Sarah M Barry, Gabriella M Barry, Dalia Martinez, Rachel D Penrod, Christopher W Cowa. The activity-regulated cytoskeleton-associated protein, Arc, functions in the nucleus accumbens shell to limit multiple triggers of cocaine-seeking behaviour. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753560. |
the activity-regulated cytoskeleton-associated protein (arc) is induced by cocaine in the nucleus accumbens (nac), an important brain reward region, but arc's nac function in sud-related behaviour remains unclear. |
2023-09-27 |
2023-10-07 |
rat |
| Suchan Chang, Hyung Kyu Kim, Yeonhee Ryu, Han Byeol Jang, DanBi Ahn, Bong Hyo Lee, Dong-Ho Youn, Bae Hwan Lee, Hee Young Ki. Mediation of mPFC-LHb pathway in acupuncture inhibition of cocaine psychomotor activity. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753567. |
to explore whether an mpfc-lhb circuit mediates the inhibitory effects of acupuncture on addictive behaviours, we examined the projection from mpfc to lhb, excitation of mpfc neurons during acupuncture stimulation, the effects of optogenetic modulation of mpfc-lhb on ht7 inhibition of cocaine-induced locomotion and the effect of mpfc lesion on ht7 inhibition of nucleus accumbens (nac) dopamine release. |
2023-09-27 |
2023-10-07 |
rat |
| Anna E Ingebretson, Julia C Lemo. Corticotropin releasing factor alters the functional diversity of accumbal cholinergic interneurons. bioRxiv : the preprint server for biology. 2023-09-25. PMID:37745598. |
here, we investigated the spontaneous firing patterns of chis in the nucleus accumbens (nac) shell, a region of the ventral striatum. |
2023-09-25 |
2023-10-07 |
mouse |
| M I Airapetov, S O Eresko, S A Shamaeva, N M Matveev, E R Bychkov, A A Lebedev, P D Shabano. Prolonged alcohol consumption influences microRNA expression in the nucleus accumbens of the rat brain. Biomeditsinskaia khimiia. vol 69. issue 4. 2023-09-14. PMID:37705484. |
we have investigated the expression levels of mir-let7b, mir-96, mir-182, mir-155, and the mrna content of hmgb1, tlr3, tlr4 in the nucleus accumbens (nac) of the brain of rats exposed to long-term alcoholization. |
2023-09-14 |
2023-10-07 |
rat |
| Enzo Pérez-Valenzuela, Roger Hudson, Taygun Uzuneser, Marta De Felice, Hanna Szkudlarek, Walter Rushlow, Steven R Laviolett. Sex-Dependent Synergism of an Edible THC: CBD Formulation in Reducing Anxiety and Depressive-like Symptoms Following Chronic Stress. Current neuropharmacology. 2023-09-13. PMID:37702237. |
furthermore, western-blot experiments examined the expression of biomarkers associated with mood and anxiety disorders, including protein kinase b (akt), glycogen synthase kinase-3 (gsk-3), bdnf, mtor, d1, and d2 receptor in nucleus accumbens (nac) and pfc.edible thc:cbd produces significant anxiolytic and antidepressant effects only in stressed male rats. |
2023-09-13 |
2023-10-07 |
rat |
| Zachary W Hoisington, Alexandra Salvi, Sophie Laguesse, Yann Ehinger, Chhavi Shukla, Khanhky Phamluong, Dorit Ro. The small G-protein Rac1 in the dorsomedial striatum promotes alcohol-dependent structural plasticity and goal-directed learning in mice. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693512. |
actin is a major component of dendritic spines, and we previously found that alcohol alters actin composition and dendritic spine structure in the nucleus accumbens (nac) and the dorsomedial striatum (dms). |
2023-09-11 |
2023-10-07 |
mouse |
| Jing Jin, Xiu-Qin Wang, Xue Yang, Na Zhao, Zi-Jian Feng, Yu-Feng Zang, Li-Xia Yua. Abnormal individualized peak functional connectivity toward potential repetitive transcranial magnetic stimulation treatment of autism spectrum disorder. Human brain mapping. 2023-09-11. PMID:37694907. |
the nucleus accumbens (nac) was regarded as a promising effective region, which was used as a seed and individualized peak fc strength in the dlpfc was compared between asd and tdc. |
2023-09-11 |
2023-10-07 |
human |
| Su-Bin Hwang, Jae-Gyeong Lee, Youyoung Lee, Wun-A Kook, Seon-Kyung Kim, Audrey Lynn Donio, Hee-Won Min, Young-Jung Kim, Seok-Yong Lee, Choon-Gon Jan. Adinazolam, a Benzodiazepine-Type New Psychoactive Substance, Has Abuse Potential and Induces Withdrawal Symptoms in Rodents. ACS chemical neuroscience. 2023-09-11. PMID:37695876. |
after the ivsa test, an enzyme-linked immunosorbent assay (elisa) showed that adz administration significantly increased the dopamine contents in the thalamus, nucleus accumbens (nac), and ventral tegmental area (vta). |
2023-09-11 |
2023-10-07 |
mouse |
| Mary Ann Raghanti, Elaine N Miller, Danielle N Jones, Heather N Smith, Emily L Munger, Melissa K Edler, Kimberley A Phillips, William D Hopkins, Patrick R Hof, Chet C Sherwood, C Owen Lovejo. Hedonic eating, obesity, and addiction result from increased neuropeptide Y in the nucleus accumbens during human brain evolution. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 38. 2023-09-11. PMID:37695892. |
the nucleus accumbens (nac) is central to motivation and action, exhibiting one of the highest densities of neuropeptide y (npy) in the brain. |
2023-09-11 |
2023-10-07 |
human |
| Nora H Prior, Chelsea M Haakenson, Savannah Clough, Gregory F Ball, Benjamin A Sandka. Varied impacts of social relationships on neuroendocrine state. Hormones and behavior. vol 155. 2023-09-07. PMID:37678093. |
we defined neuroendocrine state by the expression of 22 genes related to 4 major signaling pathways (dopamine, steroid, nonapeptide, and opioid) in six brain regions associated with affiliation or communication [nucleus accumbens (nac), nucleus taeniae of the amygdala (tna), medial preoptic area (pom), and periaqueductal gray (pag), ventral tegmental area, and auditory cortex]. |
2023-09-07 |
2023-10-07 |
Not clear |
| Domingo Afonso-Oramas, Laura Santana-Cordón, Alejandro Lemus-Mesa, Silvia Teixidó-Trujillo, Ana Elena Rodríguez-Rodríguez, Ignacio Cruz-Muros, Miriam González-Gómez, Pedro Barroso-Chine. Drastic decline in vasoactive intestinal peptide expression in the suprachiasmatic nucleus in obese mice on a long-term high-fat diet. Brain research bulletin. 2023-09-07. PMID:37678442. |
this study aimed to elucidate the long-term effect of an obesogenic diet on the distribution and expression pattern of vip in the scn and nucleus accumbens (nac) of c57bl/6 mice. |
2023-09-07 |
2023-10-07 |
mouse |
| Stephanie Puig, Xiangning Xue, Ryan Salisbury, Micah A Shelton, Sam-Moon Kim, Mariah A Hildebrand, Jill R Glausier, Zachary Freyberg, George C Tseng, Anastasia K Yocum, David A Lewis, Marianne L Seney, Matthew L MacDonald, Ryan W Loga. Circadian rhythm disruptions associated with opioid use disorder in synaptic proteomes of human dorsolateral prefrontal cortex and nucleus accumbens. Molecular psychiatry. 2023-09-06. PMID:37674018. |
previous work indicated molecular rhythm disruptions in the human brain associated with oud, highlighting synaptic alterations in the dorsolateral prefrontal cortex (dlpfc) and nucleus accumbens (nac)-key brain regions involved in cognition and reward, and heavily implicated in the pathophysiology of oud. |
2023-09-06 |
2023-10-07 |
human |
| Yuki Moriya, Yoshiyuki Kasahara, Kana Ishihara, Frank Scott Hall, Yoko Hagino, René Hen, Kazutaka Ikeda, George R Uhl, Ichiro Sor. Heterozygous and homozygous gene knockout of the 5-HT1B receptor have different effects on methamphetamine-induced behavioral sensitization. Behavioural pharmacology. 2023-09-05. PMID:37668157. |
to clarify the action of meth in 5-ht1b ko mice the effects of meth on extracellular levels of da (daec) and 5-ht (5-htec) in the caudate putamen (cpu) and the nucleus accumbens (nac) were examined. |
2023-09-05 |
2023-09-07 |
mouse |
| Ashley K Crawley, Anirudh Sharma, Kevin R Coffey, Mark O West, David J Barke. Nucleus accumbens shell neurons' early sensitivity to cocaine is associated with future increases in drug intake. Addiction neuroscience. vol 8. 2023-09-04. PMID:37664219. |
we observed that the firing patterns of nucleus accumbens (nac) core and shell neurons exhibited increasing sensitivity to cocaine over the first 6 s-a sessions and maintained a strong negative correlation between drug intake and neuronal firing rates across chronic s-a. |
2023-09-04 |
2023-09-07 |
human |
| David J Estrin, Julianna M Kulik, Nicholas J Beacher, Anthony P Pawlak, Samuel D Klein, Mark O Wes. Acquired Alterations in Nucleus Accumbens Responsiveness to a Cocaine-Paired Discriminative Stimulus Preceding Rats' Daily Cocaine Consumption. Addiction neuroscience. vol 8. 2023-09-04. PMID:37664217. |
the nucleus accumbens (nac) is a key brain region which guides motivated behavior and is implicated in resumption. |
2023-09-04 |
2023-09-07 |
rat |
| Ssu-Ju Li, Yu-Chun Lo, Hsin-Yi Tseng, Sheng-Huang Lin, Chao-Hung Kuo, Ting-Chieh Chen, Ching-Wen Chang, Yao-Wen Liang, Yi-Chen Lin, Chih-Yu Wang, Tsai-Yu Cho, Mu-Hua Wang, Ching-Te Chen, You-Yin Che. Nucleus accumbens deep brain stimulation improves depressive-like behaviors through BDNF-mediated alterations in brain functional connectivity of dopaminergic pathway. Neurobiology of stress. vol 26. 2023-09-04. PMID:37664874. |
since anhedonia is a feature of depression and there is evidence of leading to metabolic disorder, deep brain stimulation (dbs) to the nucleus accumbens (nac) might be promising in modulating the dopaminergic pathway. |
2023-09-04 |
2023-09-07 |
mouse |
| Erin Gorman-Sandler, Breanna Robertson, Jesseca Crawford, Gabrielle Wood, Archana Ramesh, Olufunke O Arishe, R Clinton Webb, Fiona Holli. Gestational stress decreases postpartum mitochondrial respiration in the prefrontal cortex of female rats. Neurobiology of stress. vol 26. 2023-09-01. PMID:37654512. |
in the mid-postpartum, we measured mitochondrial function in the prefrontal cortex (pfc) and nucleus accumbens (nac) using high-resolution respirometry. |
2023-09-01 |
2023-09-07 |
rat |