| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Sun, Xiao-Min Lin, Dan-Hua Lu, Meng Wang, Kun Li, Sheng-Rong Li, Zheng-Qiu Li, Cheng-Jun Zhu, Zhi-Min Zhang, Chang-Yu Yan, Ming-Hai Pan, Hai-Biao Gong, Jing-Cheng Feng, Yun-Feng Cao, Feng Huang, Wan-Yang Sun, Hiroshi Kurihara, Yi-Fang Li, Wen-Jun Duan, Gen-Long Jiao, Li Zhang, Rong-Rong H. Midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons. The Journal of clinical investigation. vol 133. issue 13. 2023-07-03. PMID:37395283. |
midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons. |
2023-07-03 |
2023-08-14 |
Not clear |
| Brandon A Toth, Katie S Chang, Christian R Burges. Striatal dopamine regulates sleep states and narcolepsy-cataplexy. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37397994. |
the dopamine (da) system is implicated in both sleep-wake states and cataplexy, but little is known about the function of da release in the striatum - a major output region of midbrain da neurons - and sleep disorders. |
2023-07-03 |
2023-08-14 |
Not clear |
| Ashwani Kumar, Abhilash Prabhat, Vinod Kumar, Sanjay Kumar Bhardwa. Artificial night illumination disrupts sleep, and attenuates mood and learning in diurnal animals: evidence from behavior and gene expression studies in zebra finches. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2023-06-17. PMID:37329435. |
further, compared to controls, there was reduced mrna expression level of genes involved in the neurogenesis, neural plasticity (bdnf, dcx and egr1) and motivation (th, drd2, taar1 and htr2c; dopamine synthesis and signaling genes) in the brain (hippocampus (hp), nidopallium caudolaterale (ncl), and midbrain) of birds under dlan. |
2023-06-17 |
2023-08-14 |
Not clear |
| Attilio Iemolo, Maria De Risi, Nadia Giordano, Giulia Torromino, Cristina Somma, Diletta Cavezza, Martina Colucci, Maria Mancini, Antonio de Iure, Rocco Granata, Barbara Picconi, Paolo Calabresi, Elvira De Leonibu. Synaptic mechanisms underlying onset and progression of memory deficits caused by hippocampal and midbrain synucleinopathy. NPJ Parkinson's disease. vol 9. issue 1. 2023-06-16. PMID:37328503. |
we report that overexpression of human α-syn in the murine mesencephalon leads to late onset memory impairment and sensorimotor deficits accompanied by reduced dopamine d1 expression in the hippocampus. |
2023-06-16 |
2023-08-14 |
human |
| S Jothi, S Anita, S Sivakuma. Modified Exigent Features Block in JAN Net for Analysing SPECT Scan Images to Diagnose Early-Stage Parkinson's Disease. Current medical imaging. 2023-06-07. PMID:37282573. |
the quantitative measure of dopamine transporter (dat) in the human midbrain is generally used as a biomarker for analyzing parkinson's disease (pd). |
2023-06-07 |
2023-08-14 |
human |
| Chihiro Sato Matsumoto, Yukihisa Matsumoto, Makoto Mizunam. Roles of octopamine neurons in the vertical lobe of the mushroom body for the execution of a conditioned response in cockroaches. Neurobiology of learning and memory. 2023-05-31. PMID:37257558. |
this is analogous to the fact that midbrain dopamine neurons govern execution of learned actions in mammals. |
2023-05-31 |
2023-08-14 |
Not clear |
| Utsav Gyawali, David A Martin, Fangmiao Sun, Yulong Li, Donna Cal. Dopamine in the dorsal bed nucleus of stria terminalis signals Pavlovian sign-tracking and reward violations. eLife. vol 12. 2023-05-26. PMID:37232554. |
midbrain and striatal dopamine signals have been extremely well characterized over the past several decades, yet novel dopamine signals and functions in reward learning and motivation continue to emerge. |
2023-05-26 |
2023-08-14 |
Not clear |
| David M Bortz, Catalina M Feistritzer, Anthony A Grac. Medial prefrontal cortex to medial septum pathway activation improves cognitive flexibility in rats. The international journal of neuropsychopharmacology. 2023-05-19. PMID:37207293. |
ms activation improves strategy switching, a common measure of cognitive flexibility, via its ability to regulate midbrain dopamine (da) neuron population activity. |
2023-05-19 |
2023-08-14 |
rat |
| David Pagliaccio, Kenneth Wengler, Katherine Durham, Martine Fontaine, Meryl Rueppel, Hannah Becker, Emily Bilek, Sarah Pieper, Caroline Risdon, Guillermo Horga, Kate D Fitzgerald, Rachel Mars. Probing midbrain dopamine function in pediatric obsessive-compulsive disorder via neuromelanin-sensitive magnetic resonance imaging. Molecular psychiatry. 2023-05-17. PMID:37198261. |
probing midbrain dopamine function in pediatric obsessive-compulsive disorder via neuromelanin-sensitive magnetic resonance imaging. |
2023-05-17 |
2023-08-14 |
Not clear |
| David Pagliaccio, Kenneth Wengler, Katherine Durham, Martine Fontaine, Meryl Rueppel, Hannah Becker, Emily Bilek, Sarah Pieper, Caroline Risdon, Guillermo Horga, Kate D Fitzgerald, Rachel Mars. Probing midbrain dopamine function in pediatric obsessive-compulsive disorder via neuromelanin-sensitive magnetic resonance imaging. Molecular psychiatry. 2023-05-17. PMID:37198261. |
current results provide the first demonstration of the utility of neuromelanin-mri in pediatric psychiatry, specifically highlighting in vivo evidence for midbrain dopamine alterations in treatment-seeking youth with ocd. |
2023-05-17 |
2023-08-14 |
Not clear |
| Jie Sun, Xiao-Min Lin, Dan-Hua Lu, Meng Wang, Kun Li, Sheng-Rong Li, Zheng-Qiu Li, Cheng-Jun Zhu, Zhi-Min Zhang, Chang-Yu Yan, Ming-Hai Pan, Hai-Biao Gong, Jing-Cheng Feng, Yun-Feng Cao, Feng Huang, Wan-Yang Sun, Hiroshi Kurihara, Yi-Fang Li, Wen-Jun Duan, Gen-Long Jiao, Li Zhang, Rong-Rong H. Midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons. The Journal of clinical investigation. vol 133. issue 10. 2023-05-15. PMID:37183824. |
midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons. |
2023-05-15 |
2023-08-14 |
mouse |
| Kurt M Fraser, Heather J Pribut, Patricia H Janak, Ronald Keifli. From Prediction to Action: Dissociable Roles of Ventral Tegmental Area and Substantia Nigra Dopamine Neurons in Instrumental Reinforcement. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-15. PMID:37185097. |
midbrain dopamine neurons are critical for reinforcement and their activation is sufficient for learning about cues, actions, and outcomes. |
2023-05-15 |
2023-08-14 |
rat |
| Valeria Parrales-Macias, Patrick P Michel, Aurore Tourville, Rita Raisman-Vozari, Stéphane Haïk, Stéphane Hunot, Nicolas Bizat, Annie Lannuze. The Pesticide Chlordecone Promotes Parkinsonism-like Neurodegeneration with Tau Lesions in Midbrain Cultures and Cells. vol 12. issue 9. 2023-05-14. PMID:37174736. |
for that, we used culture systems of mouse midbrain dopamine (da) neurons and glial cells, together with the nematode |
2023-05-14 |
2023-08-14 |
mouse |
| Benjamin D Hobson, Adrien T Stanley, Mark B De Los Santos, Bruce Culbertson, Eugene V Mosharov, Peter A Sims, David Sulze. Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain. Brain, behavior, and immunity. 2023-04-26. PMID:37100211. |
we find that ifn-γ induces transcription of mhc class i antigen processing and presentation machinery in all major parenchymal cell types in the ventral midbrain in vivo; however, neuronal responses are low amplitude and limited to a small set of genes, mhc class ii expression and cellular proliferation are restricted to microglia, and dopamine neuronal responses require cell autonomous expression of ifngr1. |
2023-04-26 |
2023-08-14 |
mouse |
| Malika S Datta, Yannan Chen, Shradha Chauhan, Jing Zhang, Estanislao Daniel De La Cruz, Cheng Gong, Raju Tome. Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system. bioRxiv : the preprint server for biology. 2023-04-24. PMID:37090584. |
here, we develop and utilize a high-resolution whole-brain phenotyping approach to show that repeated ketamine administration leads to a dosage-dependent decrease of dopamine (da) neurons in the behavior state-related midbrain regions and, conversely, an increase within the hypothalamus. |
2023-04-24 |
2023-08-14 |
Not clear |
| Hanna K Isotalus, Will J Carr, Jonathan Blackman, George G Averill, Oliver Radtke, James Selwood, Rachel Williams, Elizabeth Ford, Liz McCullagh, James McErlane, Cian O'Donnell, Claire Durant, Ullrich Bartsch, Matt W Jones, Carlos Muñoz-Neira, Alfie R Wearn, John P Grogan, Elizabeth J Coulthar. L-DOPA increases slow-wave sleep duration and selectively modulates memory persistence in older adults. Frontiers in behavioral neuroscience. vol 17. 2023-04-24. PMID:37091594. |
dopamine projections between the midbrain and hippocampus potentially support memory processes during slow wave sleep. |
2023-04-24 |
2023-08-14 |
Not clear |
| Ying S Chao, Jeffrey Parrilla-Carrero, Maya Eid, Oliver P Culver, Tyler B Jackson, Rachel Lipat, Makoto Taniguchi, Thomas C Jho. Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats. Cell reports. vol 42. issue 5. 2023-04-21. PMID:37083325. |
however, cocaine also blocks serotonin uptake, which we show drives, in rats, individually variable aversive effects that depend on serotonin 2c receptors (5-ht2crs) in the rostromedial tegmental nucleus (rmtg), a major gabaergic afferent to midbrain dopamine neurons. |
2023-04-21 |
2023-08-14 |
rat |
| Jyoti C Patel, Kenneth D Carr, Margaret E Ric. Actions and Consequences of Insulin in the Striatum. Biomolecules. vol 13. issue 3. 2023-03-29. PMID:36979453. |
in the brain, insulin has well-established actions in the hypothalamus, as well as at the level of mesolimbic dopamine neurons in the midbrain. |
2023-03-29 |
2023-08-14 |
Not clear |
| Matthew H Higgs, James A Jones, Charles J Wilson, Michael J Beckstea. SK and Kv4 channels limit spike timing perturbations in pacemaking dopamine neurons. eNeuro. 2023-03-27. PMID:36973012. |
midbrain dopamine (da) neurons are among the best characterized pacemaker neurons, having intrinsic, rhythmic firing activity even in the absence of synaptic input. |
2023-03-27 |
2023-08-14 |
mouse |
| Zheng-Xiong Xi, Briana Hempel, Madeline Crissman, Sruti Pari, Benjamin Klein, Guo-Hua Bi, Hannah Alto. PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice. Research square. 2023-03-13. PMID:36909477. |
pparα and pparγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice. |
2023-03-13 |
2023-08-14 |
mouse |